Drosophila melanogaster

74 known processes

tna (Dmel_CG7958)

tonalli

(Aliases: l(3)S058302,l(3)rI075,CG7958,Dmel\CG7958,anon-WO0118547.590,0583/02,l(3)L6731)

tna biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin mediated maintenance of transcriptionGO:004809670.652
regulation of gene expression epigeneticGO:00400291280.356
male courtship behavior veined wing vibrationGO:0016545210.322
male courtship behavior veined wing generated song productionGO:0045433200.230
autophagyGO:00069141080.218
cell cell signaling involved in cell fate commitmentGO:00451682100.213
positive regulation of gene expressionGO:00106282900.205
chromatin remodelingGO:0006338720.165
appendage developmentGO:00487364010.154
lateral inhibitionGO:00463312060.143
single organism behaviorGO:00447083910.138
positive regulation of macromolecule metabolic processGO:00106044050.136
single organism cellular localizationGO:19025801800.125
negative regulation of gene expressionGO:00106293870.118
imaginal disc derived appendage developmentGO:00487373990.115
antimicrobial humoral responseGO:0019730990.112
regionalizationGO:00030024160.106
negative regulation of macromolecule biosynthetic processGO:00105582700.103
cell proliferationGO:00082832990.100
Mouse
negative regulation of nitrogen compound metabolic processGO:00511722650.100
positive regulation of biosynthetic processGO:00098913160.099
imaginal disc derived appendage morphogenesisGO:00351143950.096
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.094
establishment of localization in cellGO:00516494020.093
regulation of response to stressGO:00801342000.092
muscle structure developmentGO:00610612240.092
negative regulation of transcription dna templatedGO:00458922370.091
regulation of multi organism processGO:00439001310.090
positive regulation of transcription dna templatedGO:00458932660.090
sensory organ morphogenesisGO:00905962600.089
response to organic substanceGO:00100332840.088
skeletal muscle adaptationGO:004350110.085
positive regulation of nucleobase containing compound metabolic processGO:00459353320.083
compound eye morphogenesisGO:00017452490.082
chromatin silencingGO:0006342760.081
wing disc morphogenesisGO:00074723440.081
protein modification by small protein conjugation or removalGO:00706471060.081
post embryonic appendage morphogenesisGO:00351203850.079
vesicle mediated transportGO:00161923810.079
compound eye developmentGO:00487493070.079
regulation of cellular component biogenesisGO:00440872010.077
positive regulation of macromolecule biosynthetic processGO:00105572830.077
chemotaxisGO:00069352490.076
protein modification by small protein removalGO:0070646280.075
appendage morphogenesisGO:00351073970.071
positive regulation of gene expression epigeneticGO:0045815160.070
positive regulation of defense response to bacteriumGO:1900426230.070
muscle tissue developmentGO:0060537300.066
cytoskeleton dependent cytokinesisGO:0061640810.065
male courtship behavior veined wing extensionGO:0048065220.064
response to other organismGO:00517072930.064
regulation of rna splicingGO:0043484690.063
negative regulation of rna biosynthetic processGO:19026792400.063
response to external biotic stimulusGO:00432072930.061
intracellular signal transductionGO:00355563000.060
positive regulation of response to external stimulusGO:0032103440.059
myotube differentiationGO:0014902460.058
regulation of cell cycle phase transitionGO:19019871300.058
regulation of defense responseGO:00313471020.058
locomotory behaviorGO:00076261760.057
neurological system processGO:00508773580.056
negative regulation of rna metabolic processGO:00512532510.056
regulation of production of molecular mediator of immune responseGO:0002700440.056
eye morphogenesisGO:00485922600.054
positive regulation of rna metabolic processGO:00512542710.054
response to bacteriumGO:00096171980.053
regulation of antimicrobial humoral responseGO:0002759500.052
programmed cell deathGO:00125012570.051
negative regulation of nucleobase containing compound metabolic processGO:00459342610.051
gene silencing by rnaGO:0031047570.050
stem cell differentiationGO:00488631170.050
regulation of molecular functionGO:00650092170.050
developmental programmed cell deathGO:00106231380.049
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.048
transcription from rna polymerase ii promoterGO:00063663680.047
Human Mouse
cell deathGO:00082192790.047
response to nutrient levelsGO:00316671140.047
organonitrogen compound biosynthetic processGO:19015661170.046
response to biotic stimulusGO:00096072940.046
negative regulation of cell proliferationGO:0008285690.045
positive regulation of nitrogen compound metabolic processGO:00511733540.045
establishment or maintenance of cell polarityGO:00071631670.045
taxisGO:00423303040.044
response to alcoholGO:0097305950.044
regulation of immune effector processGO:0002697520.043
negative regulation of response to stimulusGO:00485852580.043
negative regulation of cell communicationGO:00106482230.043
striated muscle adaptationGO:001488810.042
posttranscriptional regulation of gene expressionGO:00106081450.042
gene silencingGO:00164581380.041
sensory perception of mechanical stimulusGO:0050954720.041
adult behaviorGO:00305341370.041
cellular catabolic processGO:00442483720.041
regulation of immune system processGO:00026821760.040
myotube cell developmentGO:001490430.040
embryonic axis specificationGO:00005781070.039
eye photoreceptor cell differentiationGO:00017541450.038
positive regulation of endopeptidase activityGO:0010950260.037
negative regulation of cell cycle processGO:00109481090.037
regulation of nf kappab import into nucleusGO:004234510.037
deathGO:00162652840.037
negative regulation of developmental processGO:00510932010.037
dendrite developmentGO:00163582040.037
negative regulation of cellular biosynthetic processGO:00313272770.037
retina development in camera type eyeGO:006004140.036
negative regulation of stem cell proliferationGO:2000647300.036
regulation of multicellular organismal developmentGO:20000264140.035
positive regulation of immune effector processGO:0002699280.035
cellular response to chemical stimulusGO:00708871990.035
skeletal muscle fiber developmentGO:004874130.035
response to mechanical stimulusGO:0009612280.034
protein dna complex assemblyGO:0065004630.034
negative regulation of nucleic acid templated transcriptionGO:19035072400.034
response to ketoneGO:1901654340.034
regulation of synapse assemblyGO:0051963940.033
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.033
positive regulation of nf kappab import into nucleusGO:004234610.033
regulation of humoral immune responseGO:0002920510.033
regulation of cell proliferationGO:00421271630.032
Mouse
protein modification processGO:00362114380.032
regulation of erbb signaling pathwayGO:1901184420.032
regulation of immune responseGO:00507761180.032
histolysisGO:00075591020.032
protein localizationGO:00081042840.031
nf kappab import into nucleusGO:004234810.031
autophagic cell deathGO:0048102830.031
immune responseGO:00069552460.031
endocytosisGO:00068973100.030
antimicrobial peptide productionGO:0002775460.030
cytokinesisGO:0000910900.030
cellular response to dna damage stimulusGO:00069742230.030
sex differentiationGO:0007548810.030
mitotic cytokinesisGO:0000281500.029
necrotic cell deathGO:007026510.029
innate immune responseGO:00450871440.029
tripartite regional subdivisionGO:00073511030.029
positive regulation of cellular biosynthetic processGO:00313283160.029
establishment of protein localizationGO:00451841630.029
regulation of gene silencingGO:0060968630.029
compound eye cone cell differentiationGO:0042675130.028
regulation of chromatin silencingGO:0031935360.028
eye developmentGO:00016543230.028
cell cycle phase transitionGO:00447701400.028
muscle organ developmentGO:00075171270.028
axon developmentGO:00615642970.028
positive regulation of immune responseGO:0050778630.028
skeletal muscle organ developmentGO:0060538480.027
cellular protein modification processGO:00064644380.027
male gamete generationGO:00482322010.027
mesenchymal cell developmentGO:001403110.027
negative regulation of chromatin silencingGO:003193690.027
regulation of defense response to bacteriumGO:1900424300.027
induction of programmed cell death by hormonesGO:0035081120.027
protein deubiquitinationGO:0016579170.026
negative regulation of biosynthetic processGO:00098902770.026
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.026
positive regulation of nucleic acid templated transcriptionGO:19035082660.026
synapse assemblyGO:00074161430.026
alternative mrna splicing via spliceosomeGO:0000380600.025
cell divisionGO:00513012480.025
positive regulation of production of molecular mediator of immune responseGO:0002702280.025
regulation of programmed cell deathGO:00430671520.025
regulation of cellular localizationGO:00603411360.025
positive regulation of cellular component organizationGO:00511301560.025
induction of programmed cell death by ecdysoneGO:0035078120.025
salivary gland cell autophagic cell deathGO:0035071830.025
regulation of mrna metabolic processGO:1903311720.024
imaginal disc derived wing vein morphogenesisGO:0008586440.024
response to ecdysoneGO:0035075340.024
positive regulation of multicellular organismal processGO:00512401430.024
localization of cellGO:00516742570.024
positive regulation of multi organism processGO:0043902400.024
mesenchymal cell differentiationGO:004876210.024
axonogenesisGO:00074092900.024
wnt signaling pathwayGO:0016055980.024
photoreceptor cell differentiationGO:00465301700.024
striated muscle cell differentiationGO:0051146900.024
regulation of intracellular transportGO:0032386640.024
cellular response to ketoneGO:1901655170.023
negative regulation of signalingGO:00230572190.023
negative regulation of mitotic cell cycle phase transitionGO:19019911030.023
production of molecular mediator of immune responseGO:0002440460.023
positive regulation of response to stimulusGO:00485843230.023
cellular response to organic substanceGO:00713101320.023
positive regulation of response to biotic stimulusGO:0002833310.023
chromosome organizationGO:00512763600.023
imaginal disc derived wing morphogenesisGO:00074763370.022
response to radiationGO:00093141550.022
skeletal muscle tissue developmentGO:0007519130.022
stem cell developmentGO:0048864790.022
positive regulation of antimicrobial peptide productionGO:0002225280.022
antimicrobial peptide biosynthetic processGO:0002777380.022
gonad developmentGO:0008406500.022
defense response to other organismGO:00985422250.022
negative regulation of epithelial cell proliferationGO:005068040.022
sensory perceptionGO:00076001960.022
regulation of phosphorus metabolic processGO:00511742100.022
tissue deathGO:00162711020.022
regulation of cellular protein metabolic processGO:00322682430.021
regulation of localizationGO:00328792750.021
salivary gland histolysisGO:0035070880.021
matingGO:00076181200.021
negative regulation of signal transductionGO:00099682060.021
posttranscriptional gene silencing by rnaGO:0035194450.021
cellular response to radiationGO:0071478520.021
macromolecular complex assemblyGO:00650032560.021
compound eye photoreceptor cell differentiationGO:00017511400.021
neuroblast differentiationGO:0014016290.021
phagocytosisGO:00069092150.021
hindbrain developmentGO:003090220.021
larval developmentGO:00021641040.021
positive regulation of humoral immune responseGO:0002922280.021
negative regulation of nervous system developmentGO:0051961920.021
syncytium formationGO:0006949430.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.020
development of primary sexual characteristicsGO:0045137500.020
regulation of r7 cell differentiationGO:0045676150.020
cellular response to oxygen containing compoundGO:1901701790.020
response to gravityGO:0009629260.019
chemosensory behaviorGO:00076351060.019
reproductive structure developmentGO:0048608740.019
cognitionGO:00508901410.019
defense response to bacteriumGO:00427421780.019
protein complex localizationGO:003150340.019
open tracheal system developmentGO:00074242040.019
dna templated transcriptional preinitiation complex assemblyGO:0070897200.019
regulation of nervous system developmentGO:00519602480.019
regulation of transportGO:00510491810.019
cellular macromolecular complex assemblyGO:00346221530.019
protein modification by small protein conjugationGO:0032446790.019
epithelial cell developmentGO:00020642740.018
translationGO:0006412690.018
apoptotic processGO:00069151590.018
protein complex biogenesisGO:00702712010.018
humoral immune responseGO:00069591170.018
cation transmembrane transportGO:0098655880.018
camera type eye developmentGO:004301040.018
regulation of phosphorylationGO:00423251470.018
cell migrationGO:00164772380.018
dendrite morphogenesisGO:00488131990.018
detection of external stimulusGO:0009581660.018
immune system processGO:00023763470.018
imaginal disc growthGO:0007446370.018
gene silencing by mirnaGO:0035195220.018
circulatory system developmentGO:0072359820.017
Mouse
response to organic cyclic compoundGO:0014070890.017
protein importGO:0017038550.017
positive regulation of developmental processGO:00510941430.017
regulation of cell fate commitmentGO:0010453290.017
regulation of alternative mrna splicing via spliceosomeGO:0000381600.017
dna methylationGO:000630640.016
sensory perception of soundGO:0007605560.016
amide biosynthetic processGO:0043604420.016
catabolic processGO:00090564090.016
positive regulation of protein import into nucleusGO:0042307210.016
regulation of protein localization to nucleusGO:1900180290.016
positive regulation of immune system processGO:0002684680.016
neuroblast fate commitmentGO:0014017190.016
gravitaxisGO:0042332260.016
cellular amide metabolic processGO:0043603800.016
cellular response to ethanolGO:007136140.016
axon guidanceGO:00074112330.016
posttranscriptional gene silencingGO:0016441460.016
protein localization to nucleusGO:0034504550.016
mrna processingGO:00063971040.016
rna splicingGO:0008380830.016
muscle fiber developmentGO:0048747120.016
eye photoreceptor cell developmentGO:0042462810.016
organic substance transportGO:00717022570.016
regulation of protein localizationGO:0032880760.015
protein complex assemblyGO:00064612000.015
positive regulation of protein localization to nucleusGO:1900182210.015
activation of cysteine type endopeptidase activityGO:0097202170.015
synaptic growth at neuromuscular junctionGO:00511241190.015
negative regulation of multicellular organismal processGO:00512411420.015
response to sterolGO:0036314340.015
positive regulation of cell deathGO:0010942690.015
negative regulation of cellular protein metabolic processGO:0032269850.015
neuron remodelingGO:0016322290.015
response to oxygen containing compoundGO:19017002000.015
oocyte dorsal ventral axis specificationGO:0007310340.015
cellular response to abiotic stimulusGO:0071214580.015
positive regulation of molecular functionGO:00440931360.015
regulation of cell deathGO:00109411730.015
nuclear importGO:0051170510.015
mrna metabolic processGO:00160711240.014
protein import into nucleusGO:0006606510.014
establishment of ommatidial planar polarityGO:0042067490.014
neuron fate commitmentGO:0048663500.014
oocyte constructionGO:00073081120.014
negative regulation of cell differentiationGO:00455961430.014
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.014
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.014
phosphorylationGO:00163102940.014
regulation of epithelial cell proliferationGO:005067840.014
immune effector processGO:0002252980.014
regulation of photoreceptor cell differentiationGO:0046532340.014
cellular response to endogenous stimulusGO:0071495800.014
negative regulation of wnt signaling pathwayGO:0030178280.014
cell junction assemblyGO:0034329420.014
axis specificationGO:00097981670.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.014
embryonic pattern specificationGO:00098801740.014
regulation of antimicrobial peptide biosynthetic processGO:0002805380.014
regulation of protein import into nucleusGO:0042306280.014
detection of stimulus involved in sensory perceptionGO:0050906920.014
regulation of i kappab kinase nf kappab signalingGO:004312220.014
response to endogenous stimulusGO:00097191190.014
negative regulation of cell developmentGO:0010721620.014
rrna processingGO:000636430.014
dna alkylationGO:000630540.014
positive regulation of cellular amide metabolic processGO:0034250260.013
connective tissue developmentGO:006144830.013
syncytium formation by plasma membrane fusionGO:0000768430.013
cell recognitionGO:00080371020.013
oocyte differentiationGO:00099941450.013
negative regulation of immune system processGO:0002683500.013
cellular protein localizationGO:00346131600.013
positive regulation of calcium ion transportGO:005192840.013
negative regulation of protein metabolic processGO:0051248850.013
neuroblast fate determinationGO:0007400120.013
negative regulation of cell cycle phase transitionGO:19019881030.013
response to growth factorGO:0070848310.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
Human Mouse
positive regulation of rna biosynthetic processGO:19026802660.013
regulation of antimicrobial peptide productionGO:0002784440.013
syncytial blastoderm mitotic cell cycleGO:0035186210.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
cytoplasmic transportGO:00164821300.013
regulation of intracellular signal transductionGO:19025312360.013
development of primary female sexual characteristicsGO:0046545120.013
regulation of anatomical structure sizeGO:00900661630.013
regulation of mitotic cell cycleGO:00073461900.013
cell cycle comprising mitosis without cytokinesisGO:0033301250.013
synapse organizationGO:00508081960.012
single organism intracellular transportGO:19025822070.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
jak stat cascadeGO:0007259490.012
feeding behaviorGO:0007631500.012
oocyte axis specificationGO:00073091080.012
negative regulation of cellular catabolic processGO:0031330340.012
regulation of proteolysisGO:0030162870.012
response to light stimulusGO:00094161240.012
gland morphogenesisGO:00226121450.012
intracellular protein transportGO:00068861040.012
intrinsic apoptotic signaling pathwayGO:0097193160.012
defense responseGO:00069523000.012
mushroom body developmentGO:0016319700.012
associative learningGO:0008306650.012
negative regulation of erk1 and erk2 cascadeGO:007037330.012
regulation of cell shapeGO:00083601130.012
neuron projection guidanceGO:00974852410.012
induction of programmed cell deathGO:0012502120.012
positive regulation of peptidase activityGO:0010952290.012
morphogenesis of follicular epitheliumGO:0016333360.012
macromolecule catabolic processGO:00090571610.012
peptide biosynthetic processGO:0043043420.012
mapk cascadeGO:00001651070.012
positive regulation of programmed cell deathGO:0043068620.011
negative regulation of erbb signaling pathwayGO:1901185290.011
negative regulation of molecular functionGO:0044092510.011
neural precursor cell proliferationGO:0061351750.011
antibacterial humoral responseGO:0019731440.011
neuromuscular synaptic transmissionGO:0007274670.011
antibacterial peptide productionGO:0002778220.011
rna processingGO:00063961470.011
regulation of mrna processingGO:0050684710.011
extrinsic apoptotic signaling pathwayGO:009719110.011
circadian rhythmGO:00076231050.011
regulation of mapk cascadeGO:0043408920.011
anterior head developmentGO:009706530.011
regulation of cell cycle processGO:00105641810.011
photoreceptor cell developmentGO:0042461960.011
proteolysisGO:00065081920.011
intracellular transportGO:00469072280.011
tissue migrationGO:00901301550.011
regulation of neurogenesisGO:00507671580.011
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.011
regulation of endopeptidase activityGO:0052548360.011
nuclear transportGO:0051169720.011
compound eye photoreceptor developmentGO:0042051780.011
single organism carbohydrate metabolic processGO:0044723720.011
mitotic cell cycle embryonicGO:0045448380.011
muscle contractionGO:0006936130.011
positive regulation of apoptotic processGO:0043065470.010
membrane depolarizationGO:005189940.010
spermatogenesisGO:00072832000.010
muscle adaptationGO:004350010.010
regulation of apoptotic processGO:00429811300.010
nucleocytoplasmic transportGO:0006913720.010
signal transduction in response to dna damageGO:004277030.010
cellular macromolecule localizationGO:00707272200.010
wing disc pattern formationGO:0035222660.010
positive regulation of cell cycle g2 m phase transitionGO:190275120.010
regulation of cellular amide metabolic processGO:0034248390.010
cell motilityGO:00488702510.010
reproductive system developmentGO:0061458740.010
chromatin modificationGO:00165681470.010
positive regulation of phosphorus metabolic processGO:00105621390.010
negative regulation of chromosome organizationGO:2001251190.010
embryonic hemopoiesisGO:0035162260.010
g2 m transition of mitotic cell cycleGO:0000086190.010
response to nitrogen compoundGO:1901698900.010

tna disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.151
heart conduction diseaseDOID:1027300.151
disease of anatomical entityDOID:700.151
diabetes mellitusDOID:935100.020
glucose metabolism diseaseDOID:419400.020
carbohydrate metabolism diseaseDOID:005001300.020
disease of metabolismDOID:001466700.020
acquired metabolic diseaseDOID:006015800.020
type 2 diabetes mellitusDOID:935200.014
nervous system diseaseDOID:86300.011