Drosophila melanogaster

76 known processes

E(Pc) (Dmel_CG7776)

Enhancer of Polycomb

(Aliases: Dmel\CG7776,E(PC),GH05739,l(2)28-28-12,anon-48Ac,e(Pc),GH14582,CG7776,III)

E(Pc) biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron projection guidanceGO:00974852410.287
taxisGO:00423303040.249
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.237
negative regulation of gene expressionGO:00106293870.227
negative regulation of cellular biosynthetic processGO:00313272770.206
negative regulation of rna biosynthetic processGO:19026792400.200
positive regulation of nitrogen compound metabolic processGO:00511733540.198
axon developmentGO:00615642970.160
axonogenesisGO:00074092900.149
central nervous system developmentGO:00074172010.146
negative regulation of biosynthetic processGO:00098902770.139
negative regulation of rna metabolic processGO:00512532510.136
transcription from rna polymerase ii promoterGO:00063663680.129
response to organic substanceGO:00100332840.122
negative regulation of cellular metabolic processGO:00313243820.122
regulation of cell differentiationGO:00455953020.118
chromatin silencingGO:0006342760.114
immune system processGO:00023763470.113
brain developmentGO:00074201200.110
regulation of gene expression epigeneticGO:00400291280.109
chemotaxisGO:00069352490.105
single organism behaviorGO:00447083910.102
dendrite developmentGO:00163582040.099
response to abiotic stimulusGO:00096283410.094
negative regulation of transcription dna templatedGO:00458922370.094
negative regulation of macromolecule biosynthetic processGO:00105582700.092
positive regulation of response to stimulusGO:00485843230.089
positive regulation of gene expressionGO:00106282900.088
response to external biotic stimulusGO:00432072930.087
camera type eye developmentGO:004301040.083
neuromuscular junction developmentGO:00075281490.082
negative regulation of nucleobase containing compound metabolic processGO:00459342610.080
dendrite morphogenesisGO:00488131990.080
positive regulation of macromolecule biosynthetic processGO:00105572830.078
positive regulation of cellular biosynthetic processGO:00313283160.075
positive regulation of nucleobase containing compound metabolic processGO:00459353320.075
axon guidanceGO:00074112330.069
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.069
imaginal disc derived wing morphogenesisGO:00074763370.068
negative regulation of gene expression epigeneticGO:0045814770.068
positive regulation of nervous system developmentGO:0051962690.067
dendrite guidanceGO:0070983210.064
positive regulation of rna biosynthetic processGO:19026802660.064
gene silencingGO:00164581380.063
positive regulation of signal transductionGO:00099672230.059
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.058
positive regulation of rna metabolic processGO:00512542710.058
organonitrogen compound metabolic processGO:19015643180.058
positive regulation of nucleic acid templated transcriptionGO:19035082660.058
regulation of nervous system developmentGO:00519602480.058
developmental programmed cell deathGO:00106231380.057
retina development in camera type eyeGO:006004140.057
regulation of anatomical structure sizeGO:00900661630.056
hindbrain developmentGO:003090220.056
negative regulation of signal transductionGO:00099682060.055
detection of stimulusGO:00516061560.055
positive regulation of cell communicationGO:00106472500.055
chromatin remodelingGO:0006338720.055
chromosome organizationGO:00512763600.053
epithelial cell differentiationGO:00308553220.053
regulation of transcription from rna polymerase ii promoterGO:00063573780.051
negative regulation of response to stimulusGO:00485852580.051
tissue morphogenesisGO:00487292970.051
positive regulation of biosynthetic processGO:00098913160.050
negative regulation of nucleic acid templated transcriptionGO:19035072400.050
cell deathGO:00082192790.050
cellular protein modification processGO:00064644380.050
forebrain developmentGO:003090020.047
appendage morphogenesisGO:00351073970.044
regulation of response to stressGO:00801342000.044
programmed cell deathGO:00125012570.043
negative regulation of cell communicationGO:00106482230.043
establishment of localization in cellGO:00516494020.043
immune responseGO:00069552460.043
developmental growthGO:00485892800.043
deathGO:00162652840.040
response to oxygen containing compoundGO:19017002000.039
negative regulation of nitrogen compound metabolic processGO:00511722650.039
positive regulation of signalingGO:00230562430.039
intracellular signal transductionGO:00355563000.038
tissue deathGO:00162711020.038
muscle structure developmentGO:00610612240.037
regulation of multi organism processGO:00439001310.037
vesicle mediated transportGO:00161923810.037
cellular response to dna damage stimulusGO:00069742230.037
regulation of multicellular organismal developmentGO:20000264140.037
positive regulation of macromolecule metabolic processGO:00106044050.037
apoptotic processGO:00069151590.037
post embryonic appendage morphogenesisGO:00351203850.036
synaptic growth at neuromuscular junctionGO:00511241190.036
response to other organismGO:00517072930.036
determination of adult lifespanGO:00083401370.035
intracellular transportGO:00469072280.035
endocytosisGO:00068973100.035
motor neuron axon guidanceGO:0008045580.034
enzyme linked receptor protein signaling pathwayGO:00071671790.034
developmental cell growthGO:0048588520.034
response to oxidative stressGO:0006979860.034
dna metabolic processGO:00062592270.034
response to organic cyclic compoundGO:0014070890.034
negative regulation of signalingGO:00230572190.034
gland morphogenesisGO:00226121450.032
regulation of anatomical structure morphogenesisGO:00226032420.032
regulation of cell deathGO:00109411730.031
regulation of programmed cell deathGO:00430671520.031
muscle organ developmentGO:00075171270.031
neurological system processGO:00508773580.030
locomotory behaviorGO:00076261760.030
positive regulation of developmental processGO:00510941430.030
detection of chemical stimulus involved in sensory perceptionGO:0050907750.029
salivary gland histolysisGO:0035070880.029
regulation of cellular component biogenesisGO:00440872010.029
positive regulation of cellular component organizationGO:00511301560.029
positive regulation of transcription dna templatedGO:00458932660.028
humoral immune responseGO:00069591170.028
appendage developmentGO:00487364010.028
regulation of apoptotic processGO:00429811300.028
signal transduction by phosphorylationGO:00230141070.028
growthGO:00400073590.028
chromatin assembly or disassemblyGO:0006333520.028
positive regulation of cell differentiationGO:0045597640.028
chromatin organizationGO:00063252070.027
histolysisGO:00075591020.027
multicellular organismal reproductive behaviorGO:00330571100.027
sensory perception of chemical stimulusGO:00076061160.027
wnt signaling pathwayGO:0016055980.027
cell cell signaling involved in cell fate commitmentGO:00451682100.027
cellular response to external stimulusGO:0071496660.027
response to alkaloidGO:0043279260.027
carbohydrate derivative biosynthetic processGO:1901137850.026
phosphorylationGO:00163102940.026
exocrine system developmentGO:00352721620.026
regulation of localizationGO:00328792750.025
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.025
regulation of cell proliferationGO:00421271630.025
mapk cascadeGO:00001651070.025
g protein coupled receptor signaling pathwayGO:00071861360.025
organonitrogen compound biosynthetic processGO:19015661170.024
telencephalon developmentGO:002153720.024
courtship behaviorGO:0007619680.024
eye developmentGO:00016543230.024
regulation of cell shapeGO:00083601130.024
regulation of tube sizeGO:0035150460.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.023
multi multicellular organism processGO:00447061230.023
cell motilityGO:00488702510.023
response to woundingGO:0009611940.023
neural retina developmentGO:000340740.023
regulation of lipid storageGO:0010883220.023
positive regulation of phosphorus metabolic processGO:00105621390.023
regulation of immune system processGO:00026821760.022
single organism intracellular transportGO:19025822070.022
adult locomotory behaviorGO:0008344760.022
carbohydrate derivative metabolic processGO:19011352170.022
response to biotic stimulusGO:00096072940.022
phagocytosisGO:00069092150.022
gland developmentGO:00487321910.021
salivary gland morphogenesisGO:00074351450.021
organic substance transportGO:00717022570.021
atp dependent chromatin remodelingGO:0043044220.021
male mating behaviorGO:0060179700.021
maintenance of locationGO:0051235730.021
peptidyl lysine acetylationGO:0018394390.021
imaginal disc derived appendage morphogenesisGO:00351143950.021
antimicrobial humoral responseGO:0019730990.021
nucleobase containing small molecule metabolic processGO:00550861740.020
glycoprotein metabolic processGO:0009100410.020
positive regulation of nucleotide metabolic processGO:0045981550.020
protein modification processGO:00362114380.020
detection of abiotic stimulusGO:0009582660.020
regulation of cellular response to stressGO:0080135890.020
response to temperature stimulusGO:00092661060.020
regulation of immune responseGO:00507761180.020
salivary gland cell autophagic cell deathGO:0035071830.020
positive regulation of immune system processGO:0002684680.020
defense responseGO:00069523000.020
negative regulation of apoptotic processGO:0043066630.020
cellular response to chemical stimulusGO:00708871990.019
regulation of defense responseGO:00313471020.019
protein complex disassemblyGO:0043241360.019
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.019
single organism biosynthetic processGO:00447112060.019
embryo development ending in birth or egg hatchingGO:00097921520.019
synaptic transmissionGO:00072682880.019
cytoplasmic transportGO:00164821300.019
intracellular protein transportGO:00068861040.019
imaginal disc derived appendage developmentGO:00487373990.018
cell migrationGO:00164772380.018
cell recognitionGO:00080371020.018
open tracheal system developmentGO:00074242040.018
organic acid metabolic processGO:00060821030.018
body morphogenesisGO:001017120.018
cellular macromolecule localizationGO:00707272200.018
negative regulation of nervous system developmentGO:0051961920.018
regulation of molecular functionGO:00650092170.018
positive regulation of catalytic activityGO:00430851180.018
gene silencing by rnaGO:0031047570.018
sensory perception of smellGO:0007608800.018
carboxylic acid metabolic processGO:0019752920.018
response to reactive oxygen speciesGO:0000302240.018
cellular protein localizationGO:00346131600.018
positive regulation of phosphate metabolic processGO:00459371390.018
regulation of cellular amine metabolic processGO:003323830.018
regulation of cell projection organizationGO:0031344920.018
rna processingGO:00063961470.018
mitotic cell cycle embryonicGO:0045448380.018
response to extracellular stimulusGO:00099911160.017
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.017
regulation of synapse structure and activityGO:00508031280.017
detection of external stimulusGO:0009581660.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.017
defense response to bacteriumGO:00427421780.017
chromatin modificationGO:00165681470.017
wound healingGO:0042060750.017
cellular amino acid metabolic processGO:0006520610.017
macromolecular complex assemblyGO:00650032560.017
regulation of cyclic nucleotide biosynthetic processGO:0030802130.017
regulation of neurogenesisGO:00507671580.017
negative regulation of cell differentiationGO:00455961430.017
protein transportGO:00150311550.017
sleepGO:0030431490.017
hematopoietic or lymphoid organ developmentGO:0048534570.017
cellular catabolic processGO:00442483720.017
positive regulation of response to biotic stimulusGO:0002833310.016
positive regulation of lipid storageGO:001088440.016
response to radiationGO:00093141550.016
spinal cord developmentGO:002151010.016
peptidyl amino acid modificationGO:00181931050.016
regulation of cell developmentGO:00602842150.016
amine metabolic processGO:0009308120.016
regulation of neurotransmitter levelsGO:0001505380.016
connective tissue developmentGO:006144830.016
regulation of dendrite morphogenesisGO:0048814280.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
cellular amide metabolic processGO:0043603800.016
lymph gland developmentGO:0048542280.016
response to endogenous stimulusGO:00097191190.016
neuron recognitionGO:00080381010.016
embryonic morphogenesisGO:00485982060.016
cellular component assembly involved in morphogenesisGO:00109271510.016
chemosensory behaviorGO:00076351060.016
wing disc morphogenesisGO:00074723440.016
regulation of antimicrobial peptide productionGO:0002784440.015
positive regulation of cell migrationGO:003033520.015
head developmentGO:00603221350.015
regulation of response to external stimulusGO:00321011150.015
carbohydrate metabolic processGO:0005975820.015
regulation of cell cycleGO:00517262910.015
negative regulation of developmental processGO:00510932010.015
regulation of response to biotic stimulusGO:0002831630.015
negative regulation of neurogenesisGO:0050768530.015
regulation of neuron differentiationGO:00456641030.015
organic substance catabolic processGO:19015753080.015
posttranscriptional regulation of gene expressionGO:00106081450.015
camera type eye morphogenesisGO:004859320.015
regulation of i kappab kinase nf kappab signalingGO:004312220.015
developmental growth involved in morphogenesisGO:0060560650.015
immune effector processGO:0002252980.015
cellular macromolecule catabolic processGO:00442651360.015
homeostatic processGO:00425921990.014
regulation of cellular amino acid metabolic processGO:000652100.014
macromolecule catabolic processGO:00090571610.014
regulation of wnt signaling pathwayGO:0030111680.014
mrna processingGO:00063971040.014
leg disc morphogenesisGO:0007478800.014
positive regulation of cellular component biogenesisGO:0044089800.014
positive regulation of molecular functionGO:00440931360.014
catabolic processGO:00090564090.014
negative regulation of cellular component organizationGO:00511291080.014
negative regulation of cell developmentGO:0010721620.014
cellular macromolecular complex assemblyGO:00346221530.014
covalent chromatin modificationGO:00165691060.014
localization of cellGO:00516742570.014
regionalizationGO:00030024160.014
olfactory behaviorGO:0042048970.014
cell proliferationGO:00082832990.014
negative regulation of multicellular organismal processGO:00512411420.014
positive regulation of immune responseGO:0050778630.014
protein complex biogenesisGO:00702712010.014
circadian behaviorGO:0048512760.014
protein localizationGO:00081042840.013
synapse organizationGO:00508081960.013
imaginal disc derived wing margin morphogenesisGO:0008587410.013
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.013
gene silencing by mirnaGO:0035195220.013
segmentationGO:00352822070.013
response to starvationGO:0042594970.013
purine nucleoside metabolic processGO:00422781270.013
cellular amine metabolic processGO:0044106120.013
regulation of growthGO:00400082330.013
negative regulation of cell deathGO:0060548810.013
respiratory system developmentGO:00605412130.013
regulation of alternative mrna splicing via spliceosomeGO:0000381600.013
positive regulation of cell motilityGO:200014730.013
sex differentiationGO:0007548810.013
reproductive behaviorGO:00190981220.013
response to sterolGO:0036314340.013
erbb signaling pathwayGO:0038127580.013
cellular response to starvationGO:0009267610.013
mitotic g2 m transition checkpointGO:0044818700.013
response to alcoholGO:0097305950.013
anatomical structure homeostasisGO:0060249970.013
stem cell developmentGO:0048864790.013
ribonucleoprotein complex biogenesisGO:0022613310.013
protein n linked glycosylationGO:000648790.013
establishment of protein localizationGO:00451841630.013
oxoacid metabolic processGO:00434361030.013
salivary gland developmentGO:00074311620.013
protein phosphorylationGO:00064681690.013
epithelial cell developmentGO:00020642740.012
cellular response to biotic stimulusGO:007121640.012
regulation of mrna processingGO:0050684710.012
regulation of behaviorGO:0050795750.012
regulation of circadian sleep wake cycle sleepGO:0045187210.012
chromatin assemblyGO:0031497480.012
regulation of blood circulationGO:1903522210.012
cellular ketone metabolic processGO:0042180240.012
nucleotide metabolic processGO:00091171610.012
small molecule metabolic processGO:00442813050.012
stem cell maintenanceGO:0019827670.012
regulation of cellular ketone metabolic processGO:001056530.012
response to ecdysoneGO:0035075340.012
morphogenesis of embryonic epitheliumGO:0016331940.012
rhythmic behaviorGO:0007622760.012
positive regulation of phosphorylationGO:0042327870.012
mrna metabolic processGO:00160711240.012
eye antennal disc developmentGO:0035214600.012
purine nucleotide metabolic processGO:00061631460.012
ras protein signal transductionGO:0007265880.012
nucleoside catabolic processGO:00091641120.011
cell divisionGO:00513012480.011
ribonucleoprotein complex subunit organizationGO:0071826280.011
regulation of chromatin silencingGO:0031935360.011
columnar cuboidal epithelial cell developmentGO:00020662490.011
purine containing compound metabolic processGO:00725211550.011
regulation of organelle organizationGO:00330431960.011
larval developmentGO:00021641040.011
regulation of mrna metabolic processGO:1903311720.011
histone modificationGO:00165701060.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.011
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.011
male gamete generationGO:00482322010.011
protein targetingGO:0006605640.011
multicellular organismal agingGO:00102591400.011
cell growthGO:00160491080.011
interspecies interaction between organismsGO:0044419160.011
digestive system developmentGO:00551231490.011
embryonic development via the syncytial blastodermGO:00017001480.011
intracellular receptor signaling pathwayGO:0030522190.011
ribonucleoprotein complex assemblyGO:0022618230.011
positive regulation of multicellular organismal processGO:00512401430.011
synaptic target recognitionGO:0008039450.011
regulation of cell morphogenesis involved in differentiationGO:0010769610.011
stem cell differentiationGO:00488631170.011
biological adhesionGO:00226101380.011
multi organism reproductive behaviorGO:00447051210.011
cellular response to endogenous stimulusGO:0071495800.011
circadian sleep wake cycleGO:0042745280.011
negative chemotaxisGO:0050919150.011
small gtpase mediated signal transductionGO:0007264880.011
regulation of phosphate metabolic processGO:00192202100.011
cellular response to abiotic stimulusGO:0071214580.011
regulation of developmental growthGO:00486381740.011
regulation of gene silencingGO:0060968630.011
response to decreased oxygen levelsGO:0036293580.011
positive regulation of cell developmentGO:0010720610.010
response to lipopolysaccharideGO:003249640.010
nucleobase containing compound catabolic processGO:00346551650.010
columnar cuboidal epithelial cell differentiationGO:00020652560.010
defense response to other organismGO:00985422250.010
cellular component disassemblyGO:0022411460.010
positive regulation of neurogenesisGO:0050769410.010
response to bacteriumGO:00096171980.010
cellular response to molecule of bacterial originGO:007121930.010
retina morphogenesis in camera type eyeGO:006004220.010
phenol containing compound metabolic processGO:0018958570.010
cellular response to nutrient levelsGO:0031669620.010
notch signaling pathwayGO:00072191200.010
tube developmentGO:00352952440.010
neurotransmitter secretionGO:0007269350.010
negative regulation of neuron deathGO:1901215180.010
peptidyl lysine modificationGO:0018205570.010
positive regulation of response to external stimulusGO:0032103440.010
glycoprotein biosynthetic processGO:0009101410.010
histone acetylationGO:0016573380.010
positive regulation of cellular protein metabolic processGO:00322701180.010
morphogenesis of an epitheliumGO:00020092760.010
production of molecular mediator of immune responseGO:0002440460.010
ribonucleoside metabolic processGO:00091191270.010
mrna splicing via spliceosomeGO:0000398730.010

E(Pc) disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
cardiovascular system diseaseDOID:128700.036
vascular diseaseDOID:17800.036
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
nervous system diseaseDOID:86300.014
artery diseaseDOID:005082800.012