Drosophila melanogaster

160 known processes

sima (Dmel_CG7951)

similar

(Aliases: HIF-1,Sima,DMU43090,CG7951,Dmel\CG7951,bHLHe56,SIMA,Hif-1A,HIF-1alpha,dHIF-alpha,7951,l(3)j11B7,HIF-alpha/sima)

sima biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
localization of cellGO:00516742570.880
border follicle cell migrationGO:00072981130.815
ovarian follicle cell migrationGO:00072971210.782
ovarian follicle cell developmentGO:00307072480.730
ameboidal type cell migrationGO:00016671510.667
Mouse
epithelial cell migrationGO:00106311480.588
Mouse
columnar cuboidal epithelial cell developmentGO:00020662490.512
Mouse
tissue migrationGO:00901301550.509
Mouse
epithelial cell developmentGO:00020642740.490
Mouse
negative regulation of transcription dna templatedGO:00458922370.470
Rat
cell motilityGO:00488702510.437
columnar cuboidal epithelial cell differentiationGO:00020652560.421
Mouse
epithelial cell differentiationGO:00308553220.382
Mouse
transcription from rna polymerase ii promoterGO:00063663680.359
positive regulation of nucleoside metabolic processGO:0045979470.328
negative regulation of cellular biosynthetic processGO:00313272770.323
Human Rat
cell migrationGO:00164772380.299
cellular response to dna damage stimulusGO:00069742230.286
intracellular transportGO:00469072280.273
Human
negative regulation of macromolecule biosynthetic processGO:00105582700.272
Human Rat
epithelium migrationGO:00901321480.257
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071080.255
establishment of localization in cellGO:00516494020.255
Human Mouse
negative regulation of nitrogen compound metabolic processGO:00511722650.248
Human Rat
single organism intracellular transportGO:19025822070.233
Human
positive regulation of transcription dna templatedGO:00458932660.232
regulation of organelle organizationGO:00330431960.224
regulation of cellular catabolic processGO:00313291570.221
positive regulation of gtpase activityGO:0043547430.212
nucleobase containing small molecule metabolic processGO:00550861740.194
positive regulation of macromolecule metabolic processGO:00106044050.191
cell projection assemblyGO:0030031940.188
positive regulation of ras gtpase activityGO:0032320360.187
regulation of anatomical structure morphogenesisGO:00226032420.187
tube morphogenesisGO:00352391910.184
Mouse
response to oxygen containing compoundGO:19017002000.177
negative regulation of nucleobase containing compound metabolic processGO:00459342610.172
Human Rat
positive regulation of cellular catabolic processGO:0031331950.170
respiratory system developmentGO:00605412130.169
negative regulation of rna metabolic processGO:00512532510.157
Human Rat
negative regulation of rna biosynthetic processGO:19026792400.157
Human Rat
purine ribonucleoside triphosphate metabolic processGO:00092051190.154
positive regulation of molecular functionGO:00440931360.153
purine containing compound metabolic processGO:00725211550.152
open tracheal system developmentGO:00074242040.150
regulation of transcription from rna polymerase ii promoterGO:00063573780.149
negative regulation of peptidyl tyrosine phosphorylationGO:005073260.148
purine ribonucleoside metabolic processGO:00461281270.145
vesicle mediated transportGO:00161923810.139
organonitrogen compound metabolic processGO:19015643180.136
Mouse
regulation of mitotic cell cycleGO:00073461900.135
positive regulation of phosphorus metabolic processGO:00105621390.130
acylglycerol biosynthetic processGO:004646320.128
purine ribonucleotide catabolic processGO:00091541090.126
negative regulation of cellular component organizationGO:00511291080.125
positive regulation of catabolic processGO:00098961050.125
nucleoside catabolic processGO:00091641120.124
gtp catabolic processGO:0006184720.123
small molecule metabolic processGO:00442813050.119
Mouse
ribonucleoside triphosphate catabolic processGO:00092031080.117
carbohydrate derivative catabolic processGO:19011361180.116
purine nucleoside catabolic processGO:00061521120.114
positive regulation of cellular biosynthetic processGO:00313283160.113
positive regulation of gtp catabolic processGO:0033126430.111
nucleoside phosphate metabolic processGO:00067531620.111
positive regulation of phosphate metabolic processGO:00459371390.107
mitotic spindle organizationGO:00070522200.107
positive regulation of nitrogen compound metabolic processGO:00511733540.107
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.106
Rat
nucleotide metabolic processGO:00091171610.103
regulation of localizationGO:00328792750.103
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.101
secretionGO:00469031090.100
Mouse
ras protein signal transductionGO:0007265880.100
mitotic nuclear divisionGO:00070672130.097
organic substance catabolic processGO:19015753080.096
Mouse
negative regulation of biosynthetic processGO:00098902770.095
Human Rat
purine nucleotide catabolic processGO:00061951090.094
regulation of cellular component biogenesisGO:00440872010.092
regulation of cellular amino acid metabolic processGO:000652100.092
positive regulation of catalytic activityGO:00430851180.091
ribonucleoside catabolic processGO:00424541120.091
positive regulation of nucleobase containing compound metabolic processGO:00459353320.091
nucleotide catabolic processGO:00091661090.090
regulation of molecular functionGO:00650092170.088
Mouse
cellular response to chemical stimulusGO:00708871990.087
organophosphate metabolic processGO:00196371950.087
purine ribonucleotide metabolic processGO:00091501450.087
regulation of cellular ketone metabolic processGO:001056530.087
positive regulation of rna biosynthetic processGO:19026802660.086
glycosyl compound metabolic processGO:19016571270.086
purine nucleoside triphosphate metabolic processGO:00091441190.084
regulation of catalytic activityGO:00507901850.082
Mouse
regulation of response to stressGO:00801342000.082
Human Rat
regulation of gtpase activityGO:0043087440.078
chemical homeostasisGO:0048878920.078
Human Mouse Rat
gliogenesisGO:0042063800.077
cytoplasmic transport nurse cell to oocyteGO:0007303120.076
cellular nitrogen compound catabolic processGO:00442701650.075
positive regulation of nucleic acid templated transcriptionGO:19035082660.075
positive regulation of rna metabolic processGO:00512542710.074
small gtpase mediated signal transductionGO:0007264880.074
chromatin silencingGO:0006342760.073
regulation of growthGO:00400082330.072
regulation of tube architecture open tracheal systemGO:0035152680.072
single organism catabolic processGO:00447122280.071
Mouse
regulation of phosphate metabolic processGO:00192202100.071
negative regulation of developmental processGO:00510932010.069
Mouse
positive regulation of purine nucleotide catabolic processGO:0033123460.069
nucleoside phosphate catabolic processGO:19012921100.068
endocytosisGO:00068973100.068
cellular ketone metabolic processGO:0042180240.067
positive regulation of hydrolase activityGO:0051345780.066
response to alcoholGO:0097305950.066
Rat
positive regulation of lipid metabolic processGO:004583440.065
ribonucleoside metabolic processGO:00091191270.065
purine containing compound catabolic processGO:00725231120.065
regulation of ras gtpase activityGO:0032318380.064
positive regulation of nucleotide metabolic processGO:0045981550.064
regulation of cell projection organizationGO:0031344920.062
purine ribonucleoside catabolic processGO:00461301120.062
purine nucleoside triphosphate catabolic processGO:00091461080.062
protein localizationGO:00081042840.062
epithelial tube morphogenesisGO:0060562880.061
Mouse
cellular component assembly involved in morphogenesisGO:00109271510.060
gtp metabolic processGO:0046039720.060
guanosine containing compound catabolic processGO:1901069740.060
negative regulation of growthGO:0045926840.059
regulation of cellular amine metabolic processGO:003323830.059
regulation of tube size open tracheal systemGO:0035151430.059
catabolic processGO:00090564090.058
nucleoside triphosphate catabolic processGO:00091431080.058
regulation of proteolysisGO:0030162870.058
chromosome organizationGO:00512763600.058
regulation of rab protein signal transductionGO:003248370.057
organic substance transportGO:00717022570.057
Mouse
apoptotic processGO:00069151590.056
Human Zebrafish Mouse Rat
positive regulation of purine nucleotide metabolic processGO:1900544550.056
glycosyl compound catabolic processGO:19016581120.055
cell growthGO:00160491080.055
cellular amine metabolic processGO:0044106120.053
nuclear divisionGO:00002803320.053
secretion by cellGO:00329401010.052
Mouse
glycerolipid metabolic processGO:0046486340.052
regulation of ras protein signal transductionGO:0046578930.051
positive regulation of rab gtpase activityGO:003285170.051
ribonucleoside triphosphate metabolic processGO:00091991190.050
regulation of cell projection assemblyGO:0060491300.050
negative regulation of response to stimulusGO:00485852580.048
Human Mouse
neutral lipid biosynthetic processGO:004646020.048
ribonucleotide metabolic processGO:00092591450.047
regulation of nucleotide catabolic processGO:0030811480.047
negative regulation of cellular metabolic processGO:00313243820.047
Human Rat
regulation of rab gtpase activityGO:003231370.047
negative regulation of gene expressionGO:00106293870.046
Rat
regulation of phosphorus metabolic processGO:00511742100.046
regulation of small gtpase mediated signal transductionGO:0051056930.045
nucleobase containing compound catabolic processGO:00346551650.045
response to abiotic stimulusGO:00096283410.045
digestive tract developmentGO:00485651490.045
Mouse
actomyosin structure organizationGO:0031032560.045
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.044
Rat
chromatin organizationGO:00063252070.044
phagocytosisGO:00069092150.043
negative regulation of nucleic acid templated transcriptionGO:19035072400.043
Human Rat
ribonucleotide catabolic processGO:00092611090.043
response to glucoseGO:000974920.043
Zebrafish Mouse Rat
positive regulation of cellular component biogenesisGO:0044089800.043
sister chromatid segregationGO:0000819920.042
thioester metabolic processGO:003538330.042
heterocycle catabolic processGO:00467001660.042
g protein coupled receptor signaling pathwayGO:00071861360.041
nucleoside metabolic processGO:00091161270.041
triglyceride biosynthetic processGO:001943220.041
lipid localizationGO:0010876540.041
renal tubule morphogenesisGO:0061333440.041
response to monosaccharideGO:003428440.041
Zebrafish Mouse Rat
positive regulation of macromolecule biosynthetic processGO:00105572830.040
positive regulation of nucleotide catabolic processGO:0030813460.040
regulation of embryonic developmentGO:0045995680.040
regulation of transportGO:00510491810.040
Mouse
positive regulation of cell migrationGO:003033520.040
Mouse
organonitrogen compound catabolic processGO:19015651280.039
regulation of cell cycleGO:00517262910.039
cytoplasmic transportGO:00164821300.039
regulation of gtp catabolic processGO:0033124440.039
negative regulation of organelle organizationGO:0010639560.039
ribose phosphate metabolic processGO:00196931450.039
regulation of chromosome organizationGO:0033044640.038
regulation of intracellular signal transductionGO:19025312360.038
Human Mouse
triglyceride catabolic processGO:001943330.038
regulation of cell motilityGO:2000145230.038
sensory perceptionGO:00076001960.038
Mouse
spindle organizationGO:00070512530.038
gastrulationGO:0007369700.038
protein complex assemblyGO:00064612000.037
regulation of purine nucleotide catabolic processGO:0033121480.037
digestive system developmentGO:00551231490.037
Mouse
regulation of catabolic processGO:00098941700.037
actin filament based processGO:00300292200.036
intracellular signal transductionGO:00355563000.036
Human Mouse
regulation of nucleoside metabolic processGO:0009118500.036
regulation of locomotionGO:0040012420.036
renal tubule developmentGO:0061326640.035
guanosine containing compound metabolic processGO:1901068740.035
aromatic compound catabolic processGO:00194391660.035
regulation of cell cycle processGO:00105641810.035
signal releaseGO:0023061490.035
Mouse
homeostatic processGO:00425921990.035
Human Mouse Rat
stem cell differentiationGO:00488631170.035
Mouse
regulation of protein depolymerizationGO:1901879270.035
kidney developmentGO:000182230.033
branching morphogenesis of an epithelial tubeGO:0048754450.033
chromatin modificationGO:00165681470.033
organic acid metabolic processGO:00060821030.033
Mouse
purine nucleoside metabolic processGO:00422781270.033
regulation of nuclear divisionGO:0051783580.033
cholesterol homeostasisGO:004263230.032
regulation of cellular component movementGO:0051270420.032
oxoacid metabolic processGO:00434361030.032
Mouse
pseudocleavage involved in syncytial blastoderm formationGO:003058990.031
establishment of organelle localizationGO:00516561220.031
regulation of purine nucleotide metabolic processGO:1900542620.030
dna metabolic processGO:00062592270.030
positive regulation of biosynthetic processGO:00098913160.030
cellular component disassemblyGO:0022411460.030
mitotic spindle elongationGO:0000022810.030
mitotic cell cycle phase transitionGO:00447721380.029
organic cyclic compound catabolic processGO:19013611680.029
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.029
hemocyte migrationGO:0035099190.029
exocrine system developmentGO:00352721620.029
macromolecular complex assemblyGO:00650032560.029
regulation of gene expression epigeneticGO:00400291280.029
organelle assemblyGO:00709251980.029
regulation of hydrolase activityGO:0051336970.028
cell cycle phase transitionGO:00447701400.028
adult behaviorGO:00305341370.028
Fly
cellular protein complex disassemblyGO:0043624350.028
phospholipid homeostasisGO:005509110.028
digestive tract morphogenesisGO:00485461270.028
Mouse
organelle fissionGO:00482853400.027
tube developmentGO:00352952440.027
Mouse
response to hexoseGO:000974630.027
Zebrafish Mouse Rat
negative regulation of cell proliferationGO:0008285690.027
cellular response to hormone stimulusGO:0032870440.027
gene silencingGO:00164581380.027
carbohydrate derivative metabolic processGO:19011352170.027
Mouse
nucleoside triphosphate metabolic processGO:00091411200.027
peptidyl proline hydroxylationGO:001951110.027
embryonic hemopoiesisGO:0035162260.027
Mouse
negative regulation of intracellular signal transductionGO:1902532570.027
Human Mouse
photoreceptor cell developmentGO:0042461960.027
organelle localizationGO:00516401480.027
salivary gland morphogenesisGO:00074351450.026
peptidyl tyrosine modificationGO:0018212240.026
heart developmentGO:0007507820.026
Mouse
axon guidanceGO:00074112330.026
Fly
positive regulation of cellular amino acid metabolic processGO:004576400.025
protein complex biogenesisGO:00702712010.025
nitrogen compound transportGO:0071705850.025
Mouse
regulation of protein metabolic processGO:00512462560.025
response to radiationGO:00093141550.025
Mouse Rat
body morphogenesisGO:001017120.025
purine nucleotide metabolic processGO:00061631460.025
cardiovascular system developmentGO:0072358820.025
Mouse
regulation of microtubule polymerization or depolymerizationGO:0031110270.024
cell recognitionGO:00080371020.024
developmental growthGO:00485892800.024
organophosphate catabolic processGO:00464341120.024
hindgut developmentGO:0061525580.024
response to organic substanceGO:00100332840.024
regulation of cell sizeGO:0008361630.024
Rat
proteolysisGO:00065081920.024
septate junction assemblyGO:0019991260.023
regulation of behaviorGO:0050795750.023
regulation of secretionGO:0051046440.023
Mouse
glial cell differentiationGO:0010001350.023
positive regulation of phosphorylationGO:0042327870.023
embryonic morphogenesisGO:00485982060.023
Mouse
epithelial cell proliferation involved in malpighian tubule morphogenesisGO:0061331110.023
positive regulation of cell communicationGO:00106472500.023
Mouse
positive regulation of reactive oxygen species metabolic processGO:200037900.023
carboxylic acid metabolic processGO:0019752920.022
Mouse
malpighian tubule developmentGO:0072002640.022
biological adhesionGO:00226101380.022
chromosome separationGO:0051304420.022
regulation of cell migrationGO:0030334220.022
retrograde transport endosome to golgiGO:004214730.022
dorsal ventral pattern formation imaginal discGO:0007450510.022
regulation of cell differentiationGO:00455953020.022
Mouse
intercellular bridge organizationGO:0043063140.021
regulation of chromatin modificationGO:1903308280.021
response to organophosphorusGO:004668320.021
sterol homeostasisGO:005509240.021
axonogenesisGO:00074092900.021
Fly
cell cell junction organizationGO:0045216550.021
detection of stimulus involved in sensory perceptionGO:0050906920.021
cell cell junction assemblyGO:0007043380.021
cell divisionGO:00513012480.021
regulation of sequestering of triglycerideGO:001088930.021
organ growthGO:0035265560.020
regulation of apoptotic processGO:00429811300.020
Human Zebrafish Mouse Rat
regulation of meiosisGO:004002030.020
mesoderm developmentGO:0007498780.020
eye photoreceptor cell developmentGO:0042462810.020
multi multicellular organism processGO:00447061230.020
Rat
negative regulation of gene expression epigeneticGO:0045814770.020
cell proliferationGO:00082832990.020
Mouse Rat
regulation of endopeptidase activityGO:0052548360.019
cellular protein modification processGO:00064644380.019
striated muscle cell differentiationGO:0051146900.019
carbohydrate homeostasisGO:0033500120.019
Mouse Rat
ovarian nurse cell to oocyte transportGO:0007300270.019
muscle system processGO:0003012210.019
lateral inhibitionGO:00463312060.019
forebrain developmentGO:003090020.019
Mouse
cellular lipid metabolic processGO:0044255830.019
multicellular organismal agingGO:00102591400.018
positive regulation of nervous system developmentGO:0051962690.018
Mouse
endomembrane system organizationGO:00102561190.018
cellular macromolecule localizationGO:00707272200.018
amine metabolic processGO:0009308120.018
mitotic sister chromatid segregationGO:0000070870.018
chromatin remodelingGO:0006338720.018
positive regulation of response to stimulusGO:00485843230.018
Mouse
optokinetic behaviorGO:000763430.018
macromolecular complex disassemblyGO:0032984370.018
regulation of microtubule depolymerizationGO:0031114240.017
cellular response to monosaccharide stimulusGO:007132620.017
Mouse Rat
protein localization to nucleusGO:0034504550.017
somatic muscle developmentGO:0007525660.017
rab protein signal transductionGO:003248260.017
embryonic hindgut morphogenesisGO:0048619480.017
branching involved in open tracheal system developmentGO:0060446450.017
regulation of cellular response to stressGO:0080135890.017
Human Rat
multi organism reproductive behaviorGO:00447051210.017
nuclear importGO:0051170510.017
associative learningGO:0008306650.017
Mouse
regulation of protein localizationGO:0032880760.017
regulation of embryonic pattern specificationGO:1902875270.017
acyl coa metabolic processGO:000663730.017
cytokinetic processGO:0032506270.017
morphogenesis of a branching structureGO:0001763450.017
filopodium assemblyGO:0046847330.016
embryo development ending in birth or egg hatchingGO:00097921520.016
Mouse
positive regulation of cellular protein metabolic processGO:00322701180.016
single organism behaviorGO:00447083910.016
Mouse Fly
dna geometric changeGO:0032392160.016
sulfur compound metabolic processGO:0006790590.016
regulation of cellular localizationGO:00603411360.016
Mouse
regulation of protein localization to nucleusGO:1900180290.016
regulation of mitosisGO:0007088560.016
dna repairGO:0006281540.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
peptidyl tyrosine phosphorylationGO:0018108240.016
negative regulation of cell communicationGO:00106482230.016
Human Mouse
wing disc morphogenesisGO:00074723440.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.015
protein modification processGO:00362114380.015
cellular amino acid metabolic processGO:0006520610.015
response to osmotic stressGO:0006970140.015
Rat
negative regulation of signalingGO:00230572190.015
Human Mouse
response to woundingGO:0009611940.015
Mouse
determination of adult lifespanGO:00083401370.015
regulation of mapk cascadeGO:0043408920.015
ribonucleoside monophosphate catabolic processGO:0009158390.015
actin cytoskeleton organizationGO:00300362060.015
protein heterooligomerizationGO:005129140.015
response to salt stressGO:0009651110.015
Rat
purine nucleoside monophosphate metabolic processGO:0009126500.015
cell fate determinationGO:0001709910.015
positive regulation of intracellular signal transductionGO:19025331160.014
trachea developmentGO:0060438290.014
spiracle morphogenesis open tracheal systemGO:0035277220.014
imaginal disc derived appendage morphogenesisGO:00351143950.014
kidney epithelium developmentGO:007207330.014
hindbrain developmentGO:003090220.014
regulation of tyrosine phosphorylation of stat proteinGO:004250910.014
regulation of developmental growthGO:00486381740.014
regulation of chromatin organizationGO:1902275320.014
cell junction assemblyGO:0034329420.014
taxisGO:00423303040.014
Fly
neuron projection guidanceGO:00974852410.014
Fly
regulation of immune responseGO:00507761180.014
establishment of rna localizationGO:0051236470.014
regulation of sequence specific dna binding transcription factor activityGO:0051090120.014
stress activated mapk cascadeGO:0051403520.014
regulation of cell divisionGO:0051302720.014
regulation of nucleotide metabolic processGO:0006140620.014
hindgut morphogenesisGO:0007442580.014
retina development in camera type eyeGO:006004140.014
Mouse
adult locomotory behaviorGO:0008344760.013
Fly
negative regulation of mitotic cell cycleGO:00459301090.013
cilium organizationGO:0044782410.013
response to organic cyclic compoundGO:0014070890.013
Rat
heart contractionGO:0060047260.013
Mouse
regulation of peptidyl tyrosine phosphorylationGO:0050730100.013
myofibril assemblyGO:0030239360.013
negative regulation of protein metabolic processGO:0051248850.013
phosphorylationGO:00163102940.013
monocarboxylic acid transportGO:001571830.013
protein depolymerizationGO:0051261310.013
regulation of mitotic sister chromatid separationGO:0010965280.013
nephron developmentGO:007200630.013
positive regulation of cell motilityGO:200014730.013
Mouse
protein importGO:0017038550.013
cell migration involved in gastrulationGO:004207490.013
regulation of protein complex disassemblyGO:0043244290.013
lipid homeostasisGO:0055088330.013
positive regulation of signal transductionGO:00099672230.013
Mouse
muscle tissue morphogenesisGO:006041520.013
regulation of peptidase activityGO:0052547390.013
regulation of cell morphogenesisGO:00226041630.013
cellular response to nitrogen compoundGO:1901699510.013
humoral immune responseGO:00069591170.013
synaptic vesicle localizationGO:0097479530.013
exocytosisGO:0006887280.013
sensory organ morphogenesisGO:00905962600.013
regulation of cysteine type endopeptidase activityGO:2000116270.013
gland developmentGO:00487321910.013
Mouse
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.013
negative regulation of protein complex disassemblyGO:0043242230.013
nucleocytoplasmic transportGO:0006913720.013
cell deathGO:00082192790.012
Human Zebrafish Mouse Rat
establishment of protein localization to organelleGO:0072594620.012
larval somatic muscle developmentGO:0007526190.012
morphogenesis of a branching epitheliumGO:0061138450.012
mapk cascadeGO:00001651070.012
dna packagingGO:0006323910.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of response to dna damage stimulusGO:2001020230.012
agingGO:00075681430.012
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.012
protein complex disassemblyGO:0043241360.012
negative regulation of actin filament depolymerizationGO:003083520.012
muscle cell developmentGO:0055001500.012
positive regulation of defense responseGO:0031349590.012
synaptic transmissionGO:00072682880.012
single organism cell adhesionGO:0098602470.012
maintenance of locationGO:0051235730.012
negative regulation of cellular protein metabolic processGO:0032269850.012
regulation of cell growthGO:0001558430.012
cellular response to organic substanceGO:00713101320.012
l amino acid importGO:004309220.012
regulation of synapse structure and activityGO:00508031280.012
anatomical structure homeostasisGO:0060249970.012
Mouse
establishment of synaptic vesicle localizationGO:0097480500.012
tube formationGO:0035148210.012
Mouse
regulation of epithelial cell proliferationGO:005067840.012
regulation of protein kinase activityGO:0045859510.012
programmed cell deathGO:00125012570.012
Human Zebrafish Mouse Rat
eye developmentGO:00016543230.012
Mouse
oxidation reduction processGO:00551141230.012
cellular homeostasisGO:0019725800.012
Mouse Rat
nucleus localizationGO:0051647340.012
g1 s transition of mitotic cell cycleGO:0000082310.012
reactive oxygen species metabolic processGO:0072593220.012
protein acylationGO:0043543420.012
rna localizationGO:00064031150.012
malpighian tubule morphogenesisGO:0007443440.012
negative regulation of apoptotic processGO:0043066630.012
Human Mouse Rat
cell junction organizationGO:0034330570.011
neuroblast proliferationGO:0007405740.011
Mouse
positive regulation of protein metabolic processGO:00512471280.011
striated muscle cell developmentGO:0055002500.011
positive regulation of multicellular organismal processGO:00512401430.011
Human Mouse
regulation of synapse organizationGO:00508071100.011
spinal cord developmentGO:002151010.011
cellular catabolic processGO:00442483720.011
positive regulation of calcium ion transportGO:005192840.011
negative regulation of protein depolymerizationGO:1901880230.011
positive regulation of cell sizeGO:0045793210.011
Rat
defense response to gram negative bacteriumGO:0050829940.011
regulation of epithelial cell differentiationGO:003085640.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
regulation of synaptic activityGO:006002590.011
imaginal disc derived wing hair organizationGO:0035317450.011
response to starvationGO:0042594970.011
regulation of immune system processGO:00026821760.011
Mouse

sima disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.093
disease of metabolismDOID:001466700.083
acquired metabolic diseaseDOID:006015800.083
nervous system diseaseDOID:86300.046
glucose metabolism diseaseDOID:419400.043
carbohydrate metabolism diseaseDOID:005001300.043
diabetes mellitusDOID:935100.023
type 2 diabetes mellitusDOID:935200.022
sensory system diseaseDOID:005015500.014
eye and adnexa diseaseDOID:149200.014
urinary system diseaseDOID:1800.014
central nervous system diseaseDOID:33100.013
organ system cancerDOID:005068600.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011