Drosophila melanogaster

72 known processes

sca (Dmel_CG17579)

scabrous

(Aliases: mAb sca1,clone 38,Sca,Sca1b,anon-EST:Liang-38,CG17579,Dmel\CG17579,FBpp0086968,FBpp0086969)

sca biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ morphogenesisGO:00905962600.947
cell fate specificationGO:0001708710.923
compound eye morphogenesisGO:00017452490.893
organ formationGO:0048645390.891
brain developmentGO:00074201200.845
morphogenesis of a polarized epitheliumGO:0001738930.822
formation of anatomical boundaryGO:0048859370.814
notch signaling pathwayGO:00072191200.801
central nervous system developmentGO:00074172010.792
sensory organ precursor cell fate determinationGO:0016360190.790
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.765
negative regulation of nucleic acid templated transcriptionGO:19035072400.762
epithelial tube morphogenesisGO:0060562880.757
establishment of ommatidial planar polarityGO:0042067490.753
compound eye developmentGO:00487493070.739
compound eye cone cell fate commitmentGO:004267650.734
single organism behaviorGO:00447083910.724
negative regulation of biosynthetic processGO:00098902770.721
eye photoreceptor cell differentiationGO:00017541450.720
eye developmentGO:00016543230.708
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.702
regionalizationGO:00030024160.699
tissue morphogenesisGO:00487292970.681
establishment of planar polarityGO:0001736870.667
forebrain developmentGO:003090020.648
imaginal disc derived appendage morphogenesisGO:00351143950.619
stem cell maintenanceGO:0019827670.614
stem cell differentiationGO:00488631170.607
eye morphogenesisGO:00485922600.600
neurological system processGO:00508773580.566
negative regulation of cellular biosynthetic processGO:00313272770.565
olfactory behaviorGO:0042048970.558
cell fate determinationGO:0001709910.554
formation of organ boundaryGO:0010160300.549
appendage morphogenesisGO:00351073970.543
negative regulation of nitrogen compound metabolic processGO:00511722650.535
positive regulation of nucleobase containing compound metabolic processGO:00459353320.532
tube developmentGO:00352952440.529
neuroblast differentiationGO:0014016290.523
stem cell fate commitmentGO:0048865250.513
sensory organ boundary specificationGO:0008052220.512
photoreceptor cell differentiationGO:00465301700.508
organelle fissionGO:00482853400.478
negative regulation of transcription dna templatedGO:00458922370.476
epithelial cell differentiationGO:00308553220.461
positive regulation of biosynthetic processGO:00098913160.435
compound eye photoreceptor fate commitmentGO:0001752360.401
cell fate determination involved in pattern specificationGO:0060582190.399
stem cell developmentGO:0048864790.392
neuron fate determinationGO:004866410.388
retina morphogenesis in camera type eyeGO:006004220.384
negative regulation of macromolecule biosynthetic processGO:00105582700.383
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.376
dendrite morphogenesisGO:00488131990.369
positive regulation of nitrogen compound metabolic processGO:00511733540.369
head developmentGO:00603221350.361
positive regulation of transcription dna templatedGO:00458932660.361
negative regulation of rna metabolic processGO:00512532510.359
dendrite developmentGO:00163582040.356
regulation of cell fate commitmentGO:0010453290.348
establishment of tissue polarityGO:0007164870.327
negative regulation of gene expressionGO:00106293870.327
cell fate commitment involved in pattern specificationGO:0060581310.326
intracellular signal transductionGO:00355563000.321
regulation of cell cycle processGO:00105641810.317
r7 cell differentiationGO:0045466430.316
regulation of transcription from rna polymerase ii promoterGO:00063573780.305
imaginal disc derived appendage developmentGO:00487373990.299
imaginal disc derived wing vein specificationGO:0007474480.298
compound eye photoreceptor cell differentiationGO:00017511400.296
morphogenesis of an epitheliumGO:00020092760.295
appendage developmentGO:00487364010.291
positive regulation of rna biosynthetic processGO:19026802660.277
renal tubule developmentGO:0061326640.268
establishment or maintenance of cell polarityGO:00071631670.268
neuroblast proliferationGO:0007405740.267
adult behaviorGO:00305341370.262
eye photoreceptor cell fate commitmentGO:0042706370.261
positive regulation of rna metabolic processGO:00512542710.258
cell proliferationGO:00082832990.248
segmentationGO:00352822070.229
positive regulation of response to stimulusGO:00485843230.227
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.218
negative regulation of cellular metabolic processGO:00313243820.215
cell divisionGO:00513012480.207
organonitrogen compound metabolic processGO:19015643180.207
chemosensory behaviorGO:00076351060.198
neural precursor cell proliferationGO:0061351750.195
cranial nerve developmentGO:002154510.186
open tracheal system developmentGO:00074242040.184
regulation of neural precursor cell proliferationGO:2000177350.183
r1 r6 cell differentiationGO:004805240.177
mating behaviorGO:00076171060.173
epithelial cell developmentGO:00020642740.172
morphogenesis of embryonic epitheliumGO:0016331940.172
embryonic organ developmentGO:0048568500.170
imaginal disc derived wing vein morphogenesisGO:0008586440.169
branching morphogenesis of an epithelial tubeGO:0048754450.162
gland developmentGO:00487321910.162
regulation of cell fate specificationGO:0042659270.157
salivary gland developmentGO:00074311620.157
peripheral nervous system developmentGO:0007422520.154
regulation of notch signaling pathwayGO:00085931000.152
dorsal appendage formationGO:0046843470.149
camera type eye developmentGO:004301040.145
positive regulation of nucleic acid templated transcriptionGO:19035082660.142
regulation of multicellular organismal developmentGO:20000264140.138
transcription from rna polymerase ii promoterGO:00063663680.137
compound eye cone cell differentiationGO:0042675130.137
equator specificationGO:004531740.131
negative regulation of nucleobase containing compound metabolic processGO:00459342610.131
positive regulation of gene expressionGO:00106282900.130
hindbrain developmentGO:003090220.130
nuclear divisionGO:00002803320.129
regulation of cell cycleGO:00517262910.128
camera type eye photoreceptor cell differentiationGO:006021920.128
negative regulation of cell differentiationGO:00455961430.124
imaginal disc derived wing morphogenesisGO:00074763370.124
positive regulation of cellular biosynthetic processGO:00313283160.121
gastrulation with mouth forming firstGO:0001703360.121
establishment of localization in cellGO:00516494020.120
respiratory system developmentGO:00605412130.119
fusion cell fate specificationGO:003515640.118
renal system developmentGO:0072001720.116
chorion containing eggshell formationGO:00073041050.115
brain morphogenesisGO:0048854160.109
embryonic morphogenesisGO:00485982060.109
regulation of dendrite morphogenesisGO:0048814280.105
positive regulation of macromolecule biosynthetic processGO:00105572830.104
branch fusion open tracheal systemGO:0035147170.100
kidney morphogenesisGO:006099330.097
regulation of cell differentiationGO:00455953020.097
cell cell signaling involved in cell fate commitmentGO:00451682100.093
detection of stimulusGO:00516061560.092
lateral inhibitionGO:00463312060.090
tube morphogenesisGO:00352391910.090
negative regulation of multicellular organismal processGO:00512411420.089
regulation of organelle organizationGO:00330431960.087
locomotory behaviorGO:00076261760.086
endocytosisGO:00068973100.084
regulation of nervous system developmentGO:00519602480.084
negative regulation of developmental processGO:00510932010.084
branching involved in open tracheal system developmentGO:0060446450.083
regulation of neuron differentiationGO:00456641030.083
nephron epithelium developmentGO:007200930.083
negative regulation of response to stimulusGO:00485852580.082
mitotic nuclear divisionGO:00070672130.080
retina development in camera type eyeGO:006004140.079
regulation of cell proliferationGO:00421271630.078
epithelial cell proliferation involved in malpighian tubule morphogenesisGO:0061331110.077
nephron tubule morphogenesisGO:007207830.077
regulation of mitotic cell cycleGO:00073461900.076
neural retina developmentGO:000340740.074
urogenital system developmentGO:0001655720.074
epithelial cell migration open tracheal systemGO:0007427320.074
telencephalon developmentGO:002153720.073
kidney developmentGO:000182230.072
photoreceptor cell fate commitmentGO:0046552410.071
imaginal disc pattern formationGO:0007447910.069
cell cell adhesion mediated by cadherinGO:004433160.067
regulation of organ morphogenesisGO:2000027780.066
mesoderm developmentGO:0007498780.066
nephron morphogenesisGO:007202830.065
positive regulation of signal transductionGO:00099672230.065
negative regulation of neurogenesisGO:0050768530.065
negative regulation of cell developmentGO:0010721620.065
reproductive behaviorGO:00190981220.064
regulation of intracellular signal transductionGO:19025312360.064
limb developmentGO:006017310.063
positive regulation of phosphorus metabolic processGO:00105621390.063
male courtship behavior veined wing extensionGO:0048065220.062
neuron fate commitmentGO:0048663500.062
chaeta developmentGO:0022416970.062
enzyme linked receptor protein signaling pathwayGO:00071671790.061
digestive system developmentGO:00551231490.060
regulation of mitosisGO:0007088560.060
male gamete generationGO:00482322010.060
camera type eye morphogenesisGO:004859320.059
nephron developmentGO:007200630.059
malpighian tubule developmentGO:0072002640.058
anterior posterior pattern specificationGO:00099521360.057
developmental growthGO:00485892800.056
morphogenesis of a branching epitheliumGO:0061138450.056
kidney epithelium developmentGO:007207330.056
carbohydrate derivative metabolic processGO:19011352170.056
retinal cone cell differentiationGO:004267020.056
positive regulation of phosphate metabolic processGO:00459371390.055
regulation of cell morphogenesisGO:00226041630.055
positive regulation of macromolecule metabolic processGO:00106044050.055
regulation of localizationGO:00328792750.054
proteolysisGO:00065081920.054
ommatidial rotationGO:0016318200.053
morphogenesis of a branching structureGO:0001763450.053
sensory perceptionGO:00076001960.052
regulation of circadian rhythmGO:0042752490.051
negative regulation of cell cycleGO:00457861160.051
protein localization to nucleusGO:0034504550.051
antimicrobial peptide productionGO:0002775460.051
negative regulation of notch signaling pathwayGO:0045746410.050
positive regulation of proteolysisGO:0045862520.050
renal tubule morphogenesisGO:0061333440.049
tube fusionGO:0035146170.049
biological adhesionGO:00226101380.049
protein localizationGO:00081042840.049
nerve developmentGO:002167560.048
regulation of catalytic activityGO:00507901850.047
negative regulation of rna biosynthetic processGO:19026792400.046
negative regulation of nervous system developmentGO:0051961920.046
glial cell fate commitmentGO:002178130.045
gastrulation involving germ band extensionGO:0010004360.045
regulation of immune system processGO:00026821760.044
neuron recognitionGO:00080381010.044
neuron projection guidanceGO:00974852410.043
compound eye photoreceptor developmentGO:0042051780.043
adult chitin based cuticle developmentGO:000836520.043
circulatory system developmentGO:0072359820.043
regulation of phosphate metabolic processGO:00192202100.042
positive regulation of cell communicationGO:00106472500.042
epithelial cell proliferation involved in renal tubule morphogenesisGO:2001013110.042
regulation of phosphorus metabolic processGO:00511742100.042
regulation of tube architecture open tracheal systemGO:0035152680.041
post embryonic appendage morphogenesisGO:00351203850.041
positive regulation of notch signaling pathwayGO:0045747340.041
smoothened signaling pathwayGO:0007224490.040
reproductive system developmentGO:0061458740.040
protein complex assemblyGO:00064612000.040
regulation of compound eye cone cell fate specificationGO:004268240.039
axon guidanceGO:00074112330.039
growthGO:00400073590.039
axonogenesisGO:00074092900.038
nephron tubule developmentGO:007208030.037
regulation of cellular ketone metabolic processGO:001056530.037
chemotaxisGO:00069352490.037
spermatogenesisGO:00072832000.036
organic substance catabolic processGO:19015753080.036
negative regulation of fusion cell fate specificationGO:003515720.036
regulation of cell divisionGO:0051302720.036
nuclear importGO:0051170510.036
cardiac cell fate commitmentGO:0060911170.036
immune effector processGO:0002252980.036
positive regulation of protein metabolic processGO:00512471280.036
response to alcoholGO:0097305950.035
neuron fate specificationGO:0048665120.035
cellular protein localizationGO:00346131600.035
regulation of epithelial cell differentiationGO:003085640.035
bolwig s organ morphogenesisGO:000174680.034
negative regulation of mitotic cell cycleGO:00459301090.034
regulation of proteolysisGO:0030162870.034
negative regulation of cell fate specificationGO:0009996150.034
regulation of dendrite developmentGO:0050773370.034
eggshell formationGO:00307031050.034
multi organism behaviorGO:00517051750.033
muscle cell differentiationGO:00426921030.033
regulation of cellular amine metabolic processGO:003323830.033
eye photoreceptor cell developmentGO:0042462810.032
negative regulation of programmed cell deathGO:0043069720.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.032
regulation of retinal cell programmed cell deathGO:0046668180.031
segment specificationGO:0007379330.031
r3 r4 cell differentiationGO:0048056120.031
limb morphogenesisGO:003510810.031
wing disc pattern formationGO:0035222660.031
multi organism reproductive behaviorGO:00447051210.030
regulation of peptidase activityGO:0052547390.030
mushroom body developmentGO:0016319700.030
gland morphogenesisGO:00226121450.030
axon developmentGO:00615642970.030
adult chitin based cuticle pattern formationGO:003501810.030
positive regulation of molecular functionGO:00440931360.030
negative regulation of cell communicationGO:00106482230.029
nephron tubule formationGO:007207930.029
somatic stem cell maintenanceGO:0035019140.029
detection of stimulus involved in sensory perceptionGO:0050906920.029
nephron epithelium morphogenesisGO:007208830.029
regulation of neurogenesisGO:00507671580.028
positive regulation of nervous system developmentGO:0051962690.028
cell recognitionGO:00080371020.028
phosphorylationGO:00163102940.027
positive regulation of catalytic activityGO:00430851180.026
regulation of cellular protein metabolic processGO:00322682430.026
response to abiotic stimulusGO:00096283410.026
epithelial cell type specification open tracheal systemGO:0035153110.026
axon ensheathment in central nervous systemGO:003229130.026
hematopoietic or lymphoid organ developmentGO:0048534570.025
response to organic substanceGO:00100332840.025
negative regulation of stem cell differentiationGO:200073780.025
regulation of anatomical structure morphogenesisGO:00226032420.025
regulation of phosphorylationGO:00423251470.025
asymmetric protein localizationGO:0008105330.024
epidermal growth factor receptor signaling pathwayGO:0007173580.024
ocellus developmentGO:000805640.024
vesicle mediated transportGO:00161923810.024
protein modification processGO:00362114380.023
single organism cell adhesionGO:0098602470.023
cuticle pattern formationGO:0035017270.023
oenocyte developmentGO:000743880.023
notch receptor processingGO:0007220130.022
multi multicellular organism processGO:00447061230.022
r8 cell fate commitmentGO:000746060.022
immune system developmentGO:0002520570.022
positive regulation of neurogenesisGO:0050769410.022
regulation of cellular component sizeGO:0032535980.022
regulation of protein localizationGO:0032880760.022
gastrulationGO:0007369700.021
regulation of cellular amide metabolic processGO:0034248390.021
epithelial cell proliferationGO:0050673150.021
nephrocyte diaphragm assemblyGO:003605930.021
aggressive behaviorGO:0002118630.021
neuromuscular processGO:0050905210.021
immune system processGO:00023763470.021
establishment of mitotic spindle orientationGO:0000132130.021
neuroblast fate commitmentGO:0014017190.021
amide biosynthetic processGO:0043604420.021
male courtship behavior veined wing generated song productionGO:0045433200.020
response to extracellular stimulusGO:00099911160.020
anterior malpighian tubule developmentGO:0061327120.020
cytokinesisGO:0000910900.020
cellular amino acid metabolic processGO:0006520610.020
amine metabolic processGO:0009308120.020
regulation of response to stressGO:00801342000.020
tube formationGO:0035148210.020
organonitrogen compound biosynthetic processGO:19015661170.019
ovarian follicle cell developmentGO:00307072480.019
glial cell developmentGO:0021782270.019
regulation of neuron projection developmentGO:0010975690.019
glandular epithelial cell differentiationGO:000206710.019
r8 cell differentiationGO:0045465130.019
positive regulation of intracellular signal transductionGO:19025331160.019
leg disc developmentGO:0035218920.019
glial cell differentiationGO:0010001350.019
imaginal disc derived leg morphogenesisGO:0007480800.019
positive regulation of cell proliferationGO:0008284470.019
cellular response to organic substanceGO:00713101320.019
courtship behaviorGO:0007619680.018
response to oxygen containing compoundGO:19017002000.018
skin developmentGO:0043588650.018
regulation of glial cell differentiationGO:004568510.018
central nervous system neuron differentiationGO:002195380.018
establishment of spindle localizationGO:0051293220.018
regulation of protein phosphorylationGO:0001932640.018
regulation of growthGO:00400082330.018
intracellular protein transportGO:00068861040.018
spermatid developmentGO:0007286980.018
intracellular transportGO:00469072280.017
cytoskeleton dependent cytokinesisGO:0061640810.017
actin filament based processGO:00300292200.017
ras protein signal transductionGO:0007265880.017
embryonic hindgut morphogenesisGO:0048619480.017
regulation of cytoskeleton organizationGO:0051493890.017
regulation of protein metabolic processGO:00512462560.017
regulation of apoptotic processGO:00429811300.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
organic substance transportGO:00717022570.017
deathGO:00162652840.017
proximal distal pattern formationGO:0009954150.017
negative regulation of apoptotic processGO:0043066630.017
hair cell differentiationGO:0035315470.017
columnar cuboidal epithelial cell developmentGO:00020662490.017
positive regulation of cellular protein metabolic processGO:00322701180.017
cell adhesionGO:00071551360.017
regulation of endopeptidase activityGO:0052548360.016
single organism nuclear importGO:1902593510.016
regulation of molecular functionGO:00650092170.016
reproductive structure developmentGO:0048608740.016
regulation of protein modification processGO:00313991120.016
negative regulation of neuron differentiationGO:0045665160.016
embryonic heart tube developmentGO:0035050220.016
regulation of developmental pigmentationGO:0048070240.016
negative regulation of cell deathGO:0060548810.016
circulatory system processGO:0003013370.016
stem cell proliferationGO:0072089880.016
antennal developmentGO:0007469250.016
heterocycle catabolic processGO:00467001660.016
mitotic cytokinesisGO:0000281500.015
carbohydrate derivative biosynthetic processGO:1901137850.015
positive regulation of developmental processGO:00510941430.015
regulation of response to biotic stimulusGO:0002831630.015
regulation of cell deathGO:00109411730.015
organic acid metabolic processGO:00060821030.015
stem cell fate determinationGO:0048867150.015
photoreceptor cell developmentGO:0042461960.015
cellular response to dna damage stimulusGO:00069742230.015
macromolecular complex assemblyGO:00650032560.015
positive regulation of cell developmentGO:0010720610.015
muscle cell fate commitmentGO:0042693140.015
cellular response to carbohydrate stimulusGO:007132240.015
body morphogenesisGO:001017120.015
eggshell chorion assemblyGO:0007306660.015
regulation of hemocyte proliferationGO:0035206370.015
myotube cell developmentGO:001490430.014
eye antennal disc developmentGO:0035214600.014
somatic muscle developmentGO:0007525660.014
response to oxygen levelsGO:0070482590.014
negative regulation of cell cycle processGO:00109481090.014
cellular component assembly involved in morphogenesisGO:00109271510.014
peripheral nervous system neuron differentiationGO:004893480.014
positive regulation of peptidase activityGO:0010952290.014
stem cell fate specificationGO:004886620.014
hindgut morphogenesisGO:0007442580.014
negative regulation of organelle organizationGO:0010639560.014
cardiovascular system developmentGO:0072358820.014
establishment of body hair or bristle planar orientationGO:004810460.014
epidermis developmentGO:0008544650.014
single organismal cell cell adhesionGO:0016337450.014
organophosphate metabolic processGO:00196371950.014
regulation of gene expression epigeneticGO:00400291280.014
protein transportGO:00150311550.013
germ line stem cell maintenanceGO:0030718500.013
regulation of tyrosine phosphorylation of stat proteinGO:004250910.013
antennal joint developmentGO:004809850.013
male courtship behavior veined wing vibrationGO:0016545210.013
sensory perception of smellGO:0007608800.013
oxoacid metabolic processGO:00434361030.013
catabolic processGO:00090564090.013
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715780.013
regulation of r7 cell differentiationGO:0045676150.013
startle responseGO:0001964160.013
regulation of tube sizeGO:0035150460.013
larval locomotory behaviorGO:0008345270.013
oenocyte differentiationGO:000174280.013
organ growthGO:0035265560.013
peripheral nervous system neuron developmentGO:004893580.013
regulation of humoral immune responseGO:0002920510.013
spindle organizationGO:00070512530.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
regulation of antimicrobial peptide biosynthetic processGO:0002805380.013
positive regulation of cell cell adhesionGO:002240990.012
sensory neuron axon guidanceGO:009737420.012
regulation of organ growthGO:0046620420.012
secretionGO:00469031090.012
protein processingGO:0016485680.012
r7 cell developmentGO:0045467140.012
chromosome segregationGO:00070591570.012
neuronal stem cell divisionGO:0036445350.012
r3 r4 cell fate commitmentGO:0007464100.012
regulation of actin filament based processGO:0032970420.012
regulation of actin cytoskeleton organizationGO:0032956420.012
regulation of multi organism processGO:00439001310.012
regulation of immune effector processGO:0002697520.012
sex differentiationGO:0007548810.012
medulla oblongata developmentGO:002155020.012
cell cell adhesionGO:0098609260.012
central nervous system neuron developmentGO:002195480.011
associative learningGO:0008306650.011
positive regulation of phosphorylationGO:0042327870.011
inter male aggressive behaviorGO:0002121600.011
regulation of eye photoreceptor cell developmentGO:0042478130.011
positive regulation of signalingGO:00230562430.011
actin filament bundle assemblyGO:0051017260.011
protein maturationGO:0051604710.011
dorsal ventral pattern formation imaginal discGO:0007450510.011
digestive tract morphogenesisGO:00485461270.011
garland nephrocyte differentiationGO:006132130.011
regulation of stem cell proliferationGO:0072091400.011
regulation of phosphatase activityGO:001092130.011
regulation of cellular response to stressGO:0080135890.011
digestive tract developmentGO:00485651490.011
protein catabolic processGO:00301631010.011
response to nutrient levelsGO:00316671140.011
developmental programmed cell deathGO:00106231380.011
regulation of transportGO:00510491810.010
exocrine system developmentGO:00352721620.010
antennal morphogenesisGO:0048800140.010
cellular amine metabolic processGO:0044106120.010
malpighian tubule morphogenesisGO:0007443440.010
protein import into nucleusGO:0006606510.010
mapk cascadeGO:00001651070.010
regulation of epidermal cell differentiationGO:004560430.010
asymmetric stem cell divisionGO:0098722490.010

sca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
dysostosisDOID:193400.032
musculoskeletal system diseaseDOID:1700.032
spondylocostal dysostosisDOID:005056800.032
bone diseaseDOID:008000100.032
connective tissue diseaseDOID:6500.032
bone development diseaseDOID:008000600.032
cardiovascular system diseaseDOID:128700.017