IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG6454 (Dmel_CG6454)

CG6454 gene product from transcript CG6454-RC

(Aliases: Dmel\CG6454)

FLYBASE: FBgn0039187
Entrez: 42904
UniProtKB: Q9VC89
UniProtKB: Q8IMW9

Process Predictions
Disease Predictions

CG6454 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of intracellular signal transduction	GO:1902531	236	0.233
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.163
intracellular signal transduction	GO:0035556	300	0.149
regulation of phosphorus metabolic process	GO:0051174	210	0.140
positive regulation of phosphorus metabolic process	GO:0010562	139	0.128
positive regulation of phosphate metabolic process	GO:0045937	139	0.127
purine nucleoside catabolic process	GO:0006152	112	0.110
phosphorylation	GO:0016310	294	0.094
regulation of phosphate metabolic process	GO:0019220	210	0.089
small gtpase mediated signal transduction	GO:0007264	88	0.083
regulation of protein metabolic process	GO:0051246	256	0.082
carbohydrate derivative catabolic process	GO:1901136	118	0.078
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.073
positive regulation of response to stimulus	GO:0048584	323	0.072	Mouse
male gamete generation	GO:0048232	201	0.067
positive regulation of macromolecule metabolic process	GO:0010604	405	0.064
protein phosphorylation	GO:0006468	169	0.062
regulation of catalytic activity	GO:0050790	185	0.058
vesicle mediated transport	GO:0016192	381	0.056	Human Mouse
regulation of cellular protein metabolic process	GO:0032268	243	0.056
protein modification process	GO:0036211	438	0.056
positive regulation of nucleoside metabolic process	GO:0045979	47	0.054
ras protein signal transduction	GO:0007265	88	0.053
ion transport	GO:0006811	145	0.053
cellular amino acid metabolic process	GO:0006520	61	0.052
endocytosis	GO:0006897	310	0.049
oxoacid metabolic process	GO:0043436	103	0.048
positive regulation of cellular catabolic process	GO:0031331	95	0.048
regulation of cellular amine metabolic process	GO:0033238	3	0.047
aromatic compound catabolic process	GO:0019439	166	0.047
organic substance catabolic process	GO:1901575	308	0.046
cellular protein modification process	GO:0006464	438	0.046
regulation of nucleotide catabolic process	GO:0030811	48	0.044
heterocycle catabolic process	GO:0046700	166	0.044
positive regulation of protein metabolic process	GO:0051247	128	0.044
regulation of protein modification process	GO:0031399	112	0.044
regulation of molecular function	GO:0065009	217	0.043
positive regulation of catalytic activity	GO:0043085	118	0.042
organonitrogen compound metabolic process	GO:1901564	318	0.042
positive regulation of hydrolase activity	GO:0051345	78	0.042
purine nucleoside metabolic process	GO:0042278	127	0.042
small molecule metabolic process	GO:0044281	305	0.041
positive regulation of catabolic process	GO:0009896	105	0.041
organic acid metabolic process	GO:0006082	103	0.041
ribonucleotide catabolic process	GO:0009261	109	0.041
regulation of cell cycle process	GO:0010564	181	0.041
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.040
regulation of mapk cascade	GO:0043408	92	0.039
segmentation	GO:0035282	207	0.038
positive regulation of biosynthetic process	GO:0009891	316	0.038
monocarboxylic acid transport	GO:0015718	3	0.037
cellular protein complex assembly	GO:0043623	71	0.037
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.036
nucleoside triphosphate catabolic process	GO:0009143	108	0.036
nucleoside phosphate metabolic process	GO:0006753	162	0.036
cytokinesis	GO:0000910	90	0.035
nucleobase containing compound catabolic process	GO:0034655	165	0.035
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.034
macromolecular complex assembly	GO:0065003	256	0.034
nucleoside catabolic process	GO:0009164	112	0.034
carboxylic acid metabolic process	GO:0019752	92	0.033
glycosyl compound catabolic process	GO:1901658	112	0.032
positive regulation of molecular function	GO:0044093	136	0.032
regulation of hydrolase activity	GO:0051336	97	0.032
cellular nitrogen compound catabolic process	GO:0044270	165	0.031
nucleoside phosphate catabolic process	GO:1901292	110	0.030
regulation of protein complex assembly	GO:0043254	42	0.029
positive regulation of nucleotide catabolic process	GO:0030813	46	0.028
purine nucleotide catabolic process	GO:0006195	109	0.028
purine ribonucleoside metabolic process	GO:0046128	127	0.028
nucleobase containing small molecule metabolic process	GO:0055086	174	0.028
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.027
cellular catabolic process	GO:0044248	372	0.027
organic cyclic compound catabolic process	GO:1901361	168	0.027
purine ribonucleotide metabolic process	GO:0009150	145	0.027
anterior posterior axis specification	GO:0009948	109	0.026
positive regulation of cellular biosynthetic process	GO:0031328	316	0.026
purine ribonucleoside catabolic process	GO:0046130	112	0.026
ribonucleotide metabolic process	GO:0009259	145	0.026
purine ribonucleotide catabolic process	GO:0009154	109	0.025
purine containing compound catabolic process	GO:0072523	112	0.025
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.025
cellular macromolecular complex assembly	GO:0034622	153	0.024
guanosine containing compound catabolic process	GO:1901069	74	0.024
signal transduction by phosphorylation	GO:0023014	107	0.023
nucleoside triphosphate metabolic process	GO:0009141	120	0.023
positive regulation of cell communication	GO:0010647	250	0.023
mapk cascade	GO:0000165	107	0.023
positive regulation of signaling	GO:0023056	243	0.023
catabolic process	GO:0009056	409	0.022
cellular amine metabolic process	GO:0044106	12	0.022
cell division	GO:0051301	248	0.022
purine containing compound metabolic process	GO:0072521	155	0.022
regulation of nucleoside metabolic process	GO:0009118	50	0.022
proteolysis	GO:0006508	192	0.021
regulation of purine nucleotide metabolic process	GO:1900542	62	0.021
body morphogenesis	GO:0010171	2	0.021
positive regulation of proteolysis involved in cellular protein catabolic process	GO:1903052	24	0.021
amine metabolic process	GO:0009308	12	0.021
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.021
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.021
protein polymerization	GO:0051258	42	0.021
organonitrogen compound catabolic process	GO:1901565	128	0.020
regulation of ras protein signal transduction	GO:0046578	93	0.020
regulation of catabolic process	GO:0009894	170	0.019
cell motility	GO:0048870	251	0.019
response to bacterium	GO:0009617	198	0.019
protein complex assembly	GO:0006461	200	0.019
regulation of cellular component size	GO:0032535	98	0.019
positive regulation of cellular protein metabolic process	GO:0032270	118	0.018
purine nucleotide metabolic process	GO:0006163	146	0.018
regulation of cellular response to stress	GO:0080135	89	0.018
positive regulation of signal transduction	GO:0009967	223	0.018
organophosphate metabolic process	GO:0019637	195	0.018
regulation of anatomical structure size	GO:0090066	163	0.018
carbohydrate derivative metabolic process	GO:1901135	217	0.018
gtp metabolic process	GO:0046039	72	0.018
organophosphate catabolic process	GO:0046434	112	0.017
positive regulation of axonogenesis	GO:0050772	2	0.017
cellular response to endogenous stimulus	GO:0071495	80	0.017	Human Mouse
regulation of cellular catabolic process	GO:0031329	157	0.017
negative regulation of signal transduction	GO:0009968	206	0.017
regulation of cell cycle	GO:0051726	291	0.017
nucleotide metabolic process	GO:0009117	161	0.016
cell migration	GO:0016477	238	0.016
ribonucleoside catabolic process	GO:0042454	112	0.016
regulation of phosphorylation	GO:0042325	147	0.016
positive regulation of intracellular signal transduction	GO:1902533	116	0.016
embryonic pattern specification	GO:0009880	174	0.016
regulation of localization	GO:0032879	275	0.016	Human Mouse
positive regulation of proteolysis	GO:0045862	52	0.016
positive regulation of cellular component organization	GO:0051130	156	0.016	Human Mouse
positive regulation of cellular amine metabolic process	GO:0033240	0	0.016
regulation of cellular component biogenesis	GO:0044087	201	0.015
nucleotide catabolic process	GO:0009166	109	0.015
response to organic substance	GO:0010033	284	0.015	Human Mouse
regulation of cellular ketone metabolic process	GO:0010565	3	0.015
protein maturation	GO:0051604	71	0.015
homeostatic process	GO:0042592	199	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
oxidation reduction process	GO:0055114	123	0.014
negative regulation of molecular function	GO:0044092	51	0.014
establishment of protein localization	GO:0045184	163	0.014	Human
spermatogenesis	GO:0007283	200	0.014
guanosine containing compound metabolic process	GO:1901068	74	0.014
regulation of organelle organization	GO:0033043	196	0.014	Human Mouse
regulation of purine nucleotide catabolic process	GO:0033121	48	0.014
regulation of proteolysis	GO:0030162	87	0.014
glycosyl compound metabolic process	GO:1901657	127	0.013
single organism cellular localization	GO:1902580	180	0.013	Human Mouse
regulation of cellular amino acid metabolic process	GO:0006521	0	0.013
cellular response to chemical stimulus	GO:0070887	199	0.013	Human Mouse
phagocytosis	GO:0006909	215	0.013
regulation of response to external stimulus	GO:0032101	115	0.013
positive regulation of rab gtpase activity	GO:0032851	7	0.013
organelle fission	GO:0048285	340	0.013
organic substance transport	GO:0071702	257	0.013	Human Mouse
tripartite regional subdivision	GO:0007351	103	0.013
protein localization	GO:0008104	284	0.013	Human Mouse
regulation of response to stress	GO:0080134	200	0.012
positive regulation of gtpase activity	GO:0043547	43	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.012
protein complex biogenesis	GO:0070271	201	0.012
negative regulation of cell communication	GO:0010648	223	0.012
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.012
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.012
positive regulation of protein modification process	GO:0031401	58	0.012
response to biotic stimulus	GO:0009607	294	0.012
negative regulation of signaling	GO:0023057	219	0.012
single organism catabolic process	GO:0044712	228	0.012
single organism membrane organization	GO:0044802	93	0.012	Human Mouse
regulation of gtpase activity	GO:0043087	44	0.012
cellular macromolecule localization	GO:0070727	220	0.011	Human Mouse
nucleoside metabolic process	GO:0009116	127	0.011
response to abiotic stimulus	GO:0009628	341	0.011
response to peptide	GO:1901652	29	0.011	Human Mouse
regulation of transport	GO:0051049	181	0.011	Human Mouse
response to endogenous stimulus	GO:0009719	119	0.011	Human Mouse
compound eye development	GO:0048749	307	0.011
single organism behavior	GO:0044708	391	0.011
macromolecule catabolic process	GO:0009057	161	0.010
protein ubiquitination	GO:0016567	70	0.010
compound eye photoreceptor cell differentiation	GO:0001751	140	0.010
carbohydrate metabolic process	GO:0005975	82	0.010

CG6454 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.025
disease of metabolism	DOID:0014667	0.021
inherited metabolic disorder	DOID:655	0.015
nervous system disease	DOID:863	0.014
central nervous system disease	DOID:331	0.012

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