IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG10154 (Dmel_CG10154)

CG10154 gene product from transcript CG10154-RA

(Aliases: Dmel\CG10154)

Entrez: 39509
FLYBASE: FBgn0036361
UniProtKB: Q9VU72

Process Predictions
Disease Predictions

CG10154 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
exocrine system development	GO:0035272	162	0.198
gland development	GO:0048732	191	0.150
cellular catabolic process	GO:0044248	372	0.118
death	GO:0016265	284	0.116
histolysis	GO:0007559	102	0.092
salivary gland morphogenesis	GO:0007435	145	0.087
cell death	GO:0008219	279	0.085
regionalization	GO:0003002	416	0.083
salivary gland development	GO:0007431	162	0.076
transcription from rna polymerase ii promoter	GO:0006366	368	0.065
male gamete generation	GO:0048232	201	0.064
proteolysis	GO:0006508	192	0.064
small molecule metabolic process	GO:0044281	305	0.063
segmentation	GO:0035282	207	0.061
organonitrogen compound metabolic process	GO:1901564	318	0.056
blastoderm segmentation	GO:0007350	159	0.055
developmental programmed cell death	GO:0010623	138	0.055
embryonic pattern specification	GO:0009880	174	0.055
organelle fission	GO:0048285	340	0.054
digestive tract development	GO:0048565	149	0.053
programmed cell death	GO:0012501	257	0.053
anterior posterior axis specification	GO:0009948	109	0.051
single organism behavior	GO:0044708	391	0.051
spermatogenesis	GO:0007283	200	0.050
embryonic axis specification	GO:0000578	107	0.048
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.046
regulation of programmed cell death	GO:0043067	152	0.046
single organism catabolic process	GO:0044712	228	0.045
chaeta development	GO:0022416	97	0.045
negative regulation of developmental process	GO:0051093	201	0.044
organic substance catabolic process	GO:1901575	308	0.042
gland morphogenesis	GO:0022612	145	0.042
salivary gland histolysis	GO:0035070	88	0.041
mitotic cell cycle phase transition	GO:0044772	138	0.040
negative regulation of gene expression	GO:0010629	387	0.040
organic acid metabolic process	GO:0006082	103	0.039
regulation of cell differentiation	GO:0045595	302	0.039
cell proliferation	GO:0008283	299	0.039
muscle organ development	GO:0007517	127	0.039
salivary gland cell autophagic cell death	GO:0035071	83	0.039
regulation of cell cycle process	GO:0010564	181	0.038
tube morphogenesis	GO:0035239	191	0.037
digestive tract morphogenesis	GO:0048546	127	0.037
negative regulation of cell cycle	GO:0045786	116	0.036
tube development	GO:0035295	244	0.036
catabolic process	GO:0009056	409	0.036
embryonic morphogenesis	GO:0048598	206	0.036
protein maturation	GO:0051604	71	0.036
adult behavior	GO:0030534	137	0.035
negative regulation of multicellular organismal process	GO:0051241	142	0.035
purine nucleotide catabolic process	GO:0006195	109	0.035
regulation of mitotic cell cycle	GO:0007346	190	0.035
camera type eye development	GO:0043010	4	0.035
mesoderm development	GO:0007498	78	0.035
digestive system development	GO:0055123	149	0.034
regulation of cell death	GO:0010941	173	0.033
regulation of multicellular organismal development	GO:2000026	414	0.033
autophagic cell death	GO:0048102	83	0.033
heterocycle catabolic process	GO:0046700	166	0.032
tissue morphogenesis	GO:0048729	297	0.032
anterior posterior axis specification embryo	GO:0008595	103	0.032
apoptotic process	GO:0006915	159	0.030
axis specification	GO:0009798	167	0.030
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.029
protein complex assembly	GO:0006461	200	0.029
regulation of apoptotic process	GO:0042981	130	0.028
aromatic compound catabolic process	GO:0019439	166	0.028
tripartite regional subdivision	GO:0007351	103	0.028
positive regulation of programmed cell death	GO:0043068	62	0.027
epithelial cell differentiation	GO:0030855	322	0.027
mitotic nuclear division	GO:0007067	213	0.026
purine ribonucleotide catabolic process	GO:0009154	109	0.026
positive regulation of multicellular organismal process	GO:0051240	143	0.026
cellular protein modification process	GO:0006464	438	0.026
response to abiotic stimulus	GO:0009628	341	0.026
purine nucleotide metabolic process	GO:0006163	146	0.026
macromolecular complex assembly	GO:0065003	256	0.026
phosphorylation	GO:0016310	294	0.026
regulation of cell proliferation	GO:0042127	163	0.026
cell cycle phase transition	GO:0044770	140	0.026
positive regulation of biosynthetic process	GO:0009891	316	0.026
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.025
chromosome segregation	GO:0007059	157	0.025
response to lipopolysaccharide	GO:0032496	4	0.025
purine ribonucleoside metabolic process	GO:0046128	127	0.025
ribonucleotide metabolic process	GO:0009259	145	0.025
nuclear division	GO:0000280	332	0.024
small gtpase mediated signal transduction	GO:0007264	88	0.024
intracellular signal transduction	GO:0035556	300	0.024
regulation of cell cycle	GO:0051726	291	0.024
regulation of catabolic process	GO:0009894	170	0.023
spermatid differentiation	GO:0048515	114	0.023
body morphogenesis	GO:0010171	2	0.023
positive regulation of transcription dna templated	GO:0045893	266	0.023
forebrain development	GO:0030900	2	0.023
regulation of cell cycle phase transition	GO:1901987	130	0.022
oxoacid metabolic process	GO:0043436	103	0.022
carboxylic acid metabolic process	GO:0019752	92	0.022
negative regulation of cellular component organization	GO:0051129	108	0.022
ras protein signal transduction	GO:0007265	88	0.022
carbohydrate derivative metabolic process	GO:1901135	217	0.021
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.021
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.021
response to starvation	GO:0042594	97	0.021
morphogenesis of an epithelium	GO:0002009	276	0.021
ribonucleotide catabolic process	GO:0009261	109	0.020
ribonucleoside metabolic process	GO:0009119	127	0.020
organonitrogen compound catabolic process	GO:1901565	128	0.020
positive regulation of rna metabolic process	GO:0051254	271	0.020
nucleoside metabolic process	GO:0009116	127	0.020
purine containing compound catabolic process	GO:0072523	112	0.020
cellular nitrogen compound catabolic process	GO:0044270	165	0.020
anterior posterior pattern specification	GO:0009952	136	0.020
establishment of localization in cell	GO:0051649	402	0.020
protein complex biogenesis	GO:0070271	201	0.020
locomotory behavior	GO:0007626	176	0.020
retina morphogenesis in camera type eye	GO:0060042	2	0.020
ethanolamine containing compound metabolic process	GO:0042439	4	0.019
gene silencing by rna	GO:0031047	57	0.019
pigment metabolic process	GO:0042440	84	0.019
renal tubule morphogenesis	GO:0061333	44	0.019
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.019
epithelial tube morphogenesis	GO:0060562	88	0.019
nucleoside phosphate catabolic process	GO:1901292	110	0.019
ribonucleoside catabolic process	GO:0042454	112	0.019
homeostatic process	GO:0042592	199	0.019
nucleobase containing compound catabolic process	GO:0034655	165	0.019
signal transduction by phosphorylation	GO:0023014	107	0.019
kidney epithelium development	GO:0072073	3	0.019
outflow tract morphogenesis	GO:0003151	4	0.018
nucleoside phosphate metabolic process	GO:0006753	162	0.018
nephron epithelium development	GO:0072009	3	0.018
single organism cellular localization	GO:1902580	180	0.018
post embryonic appendage morphogenesis	GO:0035120	385	0.018
gastrulation	GO:0007369	70	0.018
kidney development	GO:0001822	3	0.018
aging	GO:0007568	143	0.018
steroid catabolic process	GO:0006706	1	0.018
mapk cascade	GO:0000165	107	0.018
response to monosaccharide	GO:0034284	4	0.018
regulation of epithelial cell differentiation	GO:0030856	4	0.018
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.018
regulation of intracellular signal transduction	GO:1902531	236	0.018
response to organophosphorus	GO:0046683	2	0.018
positive regulation of gene expression	GO:0010628	290	0.018
nucleobase containing small molecule metabolic process	GO:0055086	174	0.018
negative regulation of transcription dna templated	GO:0045892	237	0.018
negative regulation of response to stimulus	GO:0048585	258	0.017
appendage development	GO:0048736	401	0.017
cellular amino acid metabolic process	GO:0006520	61	0.017
negative regulation of cell differentiation	GO:0045596	143	0.017
negative regulation of apoptotic process	GO:0043066	63	0.017
organophosphate catabolic process	GO:0046434	112	0.017
purine ribonucleotide metabolic process	GO:0009150	145	0.017
positive regulation of cell communication	GO:0010647	250	0.017
regulation of cellular amine metabolic process	GO:0033238	3	0.017
nucleotide metabolic process	GO:0009117	161	0.017
organophosphate metabolic process	GO:0019637	195	0.017
amine metabolic process	GO:0009308	12	0.017
secondary metabolic process	GO:0019748	75	0.017
nucleoside catabolic process	GO:0009164	112	0.017
cell adhesion	GO:0007155	136	0.017
regulation of endopeptidase activity	GO:0052548	36	0.017
nucleoside triphosphate catabolic process	GO:0009143	108	0.016
phagocytosis	GO:0006909	215	0.016
intracellular transport	GO:0046907	228	0.016
muscle structure development	GO:0061061	224	0.016
regulation of anatomical structure morphogenesis	GO:0022603	242	0.016
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.016
cellular amine metabolic process	GO:0044106	12	0.016
response to alcohol	GO:0097305	95	0.016
purine nucleoside catabolic process	GO:0006152	112	0.016
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.016
organic cyclic compound catabolic process	GO:1901361	168	0.016
developmental maturation	GO:0021700	172	0.016
nucleoside triphosphate metabolic process	GO:0009141	120	0.016
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.016
cellular ketone metabolic process	GO:0042180	24	0.016
dendrite development	GO:0016358	204	0.016
ribose phosphate metabolic process	GO:0019693	145	0.016
connective tissue development	GO:0061448	3	0.016
photoreceptor cell differentiation	GO:0046530	170	0.016
neurological system process	GO:0050877	358	0.016
response to wounding	GO:0009611	94	0.016
positive regulation of signaling	GO:0023056	243	0.016
rna processing	GO:0006396	147	0.016
vesicle mediated transport	GO:0016192	381	0.015
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.015
regulation of phosphate metabolic process	GO:0019220	210	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.015
renal tubule development	GO:0061326	64	0.015
dendrite morphogenesis	GO:0048813	199	0.015
epidermis development	GO:0008544	65	0.015
convergent extension	GO:0060026	2	0.015
acetylcholine metabolic process	GO:0008291	2	0.015
spermatid development	GO:0007286	98	0.015
androgen metabolic process	GO:0008209	1	0.015
mitotic g2 m transition checkpoint	GO:0044818	70	0.015
regulation of protein metabolic process	GO:0051246	256	0.015
regulation of cellular amino acid metabolic process	GO:0006521	0	0.015
positive regulation of cell death	GO:0010942	69	0.015
cellular homeostasis	GO:0019725	80	0.015
regulation of molecular function	GO:0065009	217	0.015
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.015
polyol biosynthetic process	GO:0046173	3	0.015
protein localization	GO:0008104	284	0.015
regulation of ras protein signal transduction	GO:0046578	93	0.015
medium chain fatty acid metabolic process	GO:0051791	1	0.015
sensory organ morphogenesis	GO:0090596	260	0.015
cellular macromolecular complex assembly	GO:0034622	153	0.015
positive regulation of catalytic activity	GO:0043085	118	0.015
terminal region determination	GO:0007362	25	0.015
negative regulation of nervous system development	GO:0051961	92	0.014
regulation of catalytic activity	GO:0050790	185	0.014
adult locomotory behavior	GO:0008344	76	0.014
neurotransmitter metabolic process	GO:0042133	2	0.014
regulation of cellular ketone metabolic process	GO:0010565	3	0.014
response to other organism	GO:0051707	293	0.014
nephron development	GO:0072006	3	0.014
cell cycle checkpoint	GO:0000075	95	0.014
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.014
positive regulation of macromolecule metabolic process	GO:0010604	405	0.014
epithelial cell migration	GO:0010631	148	0.014
regulation of localization	GO:0032879	275	0.014
protein processing	GO:0016485	68	0.014
protein modification process	GO:0036211	438	0.014
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.014
protein modification by small protein conjugation or removal	GO:0070647	106	0.014
secondary metabolite catabolic process	GO:0090487	1	0.014
wound healing	GO:0042060	75	0.014
positive regulation of cellular biosynthetic process	GO:0031328	316	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.014
response to heat	GO:0009408	63	0.014
nephron tubule morphogenesis	GO:0072078	3	0.014
response to oxygen containing compound	GO:1901700	200	0.014
nucleotide catabolic process	GO:0009166	109	0.014
response to organic substance	GO:0010033	284	0.014
cellular response to ethanol	GO:0071361	4	0.014
mitotic g2 dna damage checkpoint	GO:0007095	69	0.014
negative regulation of cell cycle phase transition	GO:1901988	103	0.014
cellular macromolecule catabolic process	GO:0044265	136	0.013
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.013
positive regulation of rna biosynthetic process	GO:1902680	266	0.013
urogenital system development	GO:0001655	72	0.013
positive regulation of cell migration	GO:0030335	2	0.013
negative regulation of cell communication	GO:0010648	223	0.013
peripheral nervous system development	GO:0007422	52	0.013
mesenchymal cell differentiation	GO:0048762	1	0.013
neuron projection guidance	GO:0097485	241	0.013
endocytosis	GO:0006897	310	0.013
cell fate determination	GO:0001709	91	0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.013
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.013
positive regulation of cellular amine metabolic process	GO:0033240	0	0.013
response to temperature stimulus	GO:0009266	106	0.013
negative regulation of mitotic cell cycle	GO:0045930	109	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.013
negative regulation of programmed cell death	GO:0043069	72	0.013
negative regulation of cell death	GO:0060548	81	0.013
extracellular structure organization	GO:0043062	46	0.013
purine containing compound metabolic process	GO:0072521	155	0.013
regulation of lipid transport	GO:0032368	3	0.012
biological adhesion	GO:0022610	138	0.012
negative regulation of cell proliferation	GO:0008285	69	0.012
camera type eye morphogenesis	GO:0048593	2	0.012
regulation of growth	GO:0040008	233	0.012
meiotic cell cycle	GO:0051321	171	0.012
regulation of proteolysis	GO:0030162	87	0.012
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
single organism cell adhesion	GO:0098602	47	0.012
carbohydrate derivative catabolic process	GO:1901136	118	0.012
glycosyl compound metabolic process	GO:1901657	127	0.012
regulation of cell substrate adhesion	GO:0010810	2	0.012
g2 dna damage checkpoint	GO:0031572	69	0.012
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.012
defense response	GO:0006952	300	0.012
maintenance of location	GO:0051235	73	0.012
purine nucleoside metabolic process	GO:0042278	127	0.012
cellular response to chemical stimulus	GO:0070887	199	0.012
regulation of embryonic development	GO:0045995	68	0.012
axon guidance	GO:0007411	233	0.012
female meiotic division	GO:0007143	70	0.012
hindbrain development	GO:0030902	2	0.012
toxin catabolic process	GO:0009407	1	0.012
regulation of hydrolase activity	GO:0051336	97	0.012
somatic muscle development	GO:0007525	66	0.012
kidney morphogenesis	GO:0060993	3	0.012
response to hexose	GO:0009746	3	0.012
nephron tubule development	GO:0072080	3	0.012
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.011
hindgut development	GO:0061525	58	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
positive regulation of response to stimulus	GO:0048584	323	0.011
xenobiotic catabolic process	GO:0042178	1	0.011
actin filament based process	GO:0030029	220	0.011
lipid localization	GO:0010876	54	0.011
mrna processing	GO:0006397	104	0.011
single organism biosynthetic process	GO:0044711	206	0.011
positive regulation of molecular function	GO:0044093	136	0.011
epithelial cell development	GO:0002064	274	0.011
meiotic cell cycle process	GO:1903046	132	0.011
fat soluble vitamin biosynthetic process	GO:0042362	1	0.011
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.011
mesenchymal cell development	GO:0014031	1	0.011
meiotic chromosome segregation	GO:0045132	59	0.011
regulation of sequestering of calcium ion	GO:0051282	3	0.011
nephron epithelium morphogenesis	GO:0072088	3	0.011
regulation of organelle organization	GO:0033043	196	0.011
synaptic transmission	GO:0007268	288	0.011
regulation of cellular catabolic process	GO:0031329	157	0.011
dna metabolic process	GO:0006259	227	0.011
intracellular protein transport	GO:0006886	104	0.011
positive regulation of neuron apoptotic process	GO:0043525	1	0.011
cellular response to organic substance	GO:0071310	132	0.011
organic hydroxy compound catabolic process	GO:1901616	4	0.011
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.011
regulation of cellular amide metabolic process	GO:0034248	39	0.011
regulation of heart morphogenesis	GO:2000826	3	0.011
carbohydrate metabolic process	GO:0005975	82	0.011
negative regulation of cellular response to oxidative stress	GO:1900408	1	0.011
single organism intracellular transport	GO:1902582	207	0.011
chromosome separation	GO:0051304	42	0.011
negative regulation of cell development	GO:0010721	62	0.011
nucleoside monophosphate metabolic process	GO:0009123	52	0.011
response to insulin	GO:0032868	29	0.011
cell division	GO:0051301	248	0.011
positive regulation of peptidase activity	GO:0010952	29	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
negative regulation of cell cycle process	GO:0010948	109	0.010
response to external biotic stimulus	GO:0043207	293	0.010
protein catabolic process	GO:0030163	101	0.010
acetate ester metabolic process	GO:1900619	2	0.010
monocarboxylic acid transport	GO:0015718	3	0.010
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.010
respiratory system development	GO:0060541	213	0.010
eye development	GO:0001654	323	0.010
organelle fusion	GO:0048284	46	0.010
regulation of response to oxidative stress	GO:1902882	4	0.010
negative regulation of rna metabolic process	GO:0051253	251	0.010
mrna metabolic process	GO:0016071	124	0.010
regulation of phosphorus metabolic process	GO:0051174	210	0.010
torso signaling pathway	GO:0008293	21	0.010
establishment or maintenance of cell polarity	GO:0007163	167	0.010
cell recognition	GO:0008037	102	0.010
mitotic sister chromatid segregation	GO:0000070	87	0.010
regulation of cell maturation	GO:1903429	27	0.010
synapse organization	GO:0050808	196	0.010

CG10154 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.045
nervous system disease	DOID:863	0.021
eye disease	DOID:5614	0.021
eye and adnexa disease	DOID:1492	0.021
sensory system disease	DOID:0050155	0.021
acquired metabolic disease	DOID:0060158	0.015
disease of metabolism	DOID:0014667	0.015
hypertension	DOID:10763	0.014
essential hypertension	DOID:10825	0.014
artery disease	DOID:0050828	0.014
cardiovascular system disease	DOID:1287	0.014
vascular disease	DOID:178	0.014
urinary system disease	DOID:18	0.010

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