Drosophila melanogaster

66 known processes

cathD (Dmel_CG1548)

CG1548 gene product from transcript CG1548-RA

(Aliases: CT3996,CathD,CATH,T17,Dmel\CG1548,CG1548)

cathD biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
programmed cell deathGO:00125012570.533
cell deathGO:00082192790.511
tissue deathGO:00162711020.479
autophagyGO:00069141080.376
Rat
regulation of cell deathGO:00109411730.337
defense responseGO:00069523000.321
proteolysisGO:00065081920.293
Human Mouse Rat
male gamete generationGO:00482322010.264
response to mechanical stimulusGO:0009612280.256
cell proliferationGO:00082832990.252
histolysisGO:00075591020.249
exocrine system developmentGO:00352721620.222
negative regulation of signalingGO:00230572190.218
developmental programmed cell deathGO:00106231380.204
immune system processGO:00023763470.202
organic substance transportGO:00717022570.197
gland morphogenesisGO:00226121450.194
regulation of endopeptidase activityGO:0052548360.191
deathGO:00162652840.171
protein maturationGO:0051604710.168
Human Mouse
negative regulation of gene expressionGO:00106293870.152
salivary gland histolysisGO:0035070880.152
positive regulation of cell deathGO:0010942690.151
regulation of hydrolase activityGO:0051336970.149
dorsal ventral pattern formationGO:00099531330.148
cellular response to external stimulusGO:0071496660.139
salivary gland developmentGO:00074311620.137
response to abiotic stimulusGO:00096283410.135
salivary gland morphogenesisGO:00074351450.134
innate immune responseGO:00450871440.127
salivary gland cell autophagic cell deathGO:0035071830.127
macroautophagyGO:0016236420.127
rna localizationGO:00064031150.126
regulation of cell cycleGO:00517262910.122
catabolic processGO:00090564090.120
Rat
determination of adult lifespanGO:00083401370.117
cellular response to extracellular stimulusGO:0031668640.117
cellular response to mechanical stimulusGO:007126020.106
cellular ketone metabolic processGO:0042180240.103
protein complex biogenesisGO:00702712010.103
growthGO:00400073590.099
protein complex assemblyGO:00064612000.099
regulation of programmed cell deathGO:00430671520.098
positive regulation of multicellular organismal processGO:00512401430.098
gland developmentGO:00487321910.093
multicellular organismal agingGO:00102591400.093
response to other organismGO:00517072930.088
regulation of peptidase activityGO:0052547390.086
cellular response to nutrient levelsGO:0031669620.085
negative regulation of cell deathGO:0060548810.085
regulation of apoptotic processGO:00429811300.084
peptide metabolic processGO:0006518800.081
Human Mouse
apoptotic processGO:00069151590.081
transcription from rna polymerase ii promoterGO:00063663680.080
response to organic substanceGO:00100332840.080
Mouse
spermatogenesisGO:00072832000.079
response to organic cyclic compoundGO:0014070890.078
positive regulation of macromolecule metabolic processGO:00106044050.077
response to glucoseGO:000974920.075
regulation of protein metabolic processGO:00512462560.073
Human Mouse
intracellular signal transductionGO:00355563000.069
Human
larval developmentGO:00021641040.066
positive regulation of nucleobase containing compound metabolic processGO:00459353320.066
response to hexoseGO:000974630.065
regulation of response to nutrient levelsGO:0032107180.065
cellular catabolic processGO:00442483720.064
Rat
response to bacteriumGO:00096171980.061
ectopic germ cell programmed cell deathGO:003523480.060
regulation of response to stressGO:00801342000.060
positive regulation of biosynthetic processGO:00098913160.060
response to monosaccharideGO:003428440.057
regulation of cell proliferationGO:00421271630.057
secretion by cellGO:00329401010.056
establishment of localization in cellGO:00516494020.056
agingGO:00075681430.055
lateral inhibitionGO:00463312060.055
positive regulation of cellular catabolic processGO:0031331950.055
regulation of response to external stimulusGO:00321011150.054
zymogen activationGO:0031638200.053
regulation of cysteine type endopeptidase activityGO:2000116270.052
organonitrogen compound metabolic processGO:19015643180.052
Human Mouse
negative regulation of cell cycle phase transitionGO:19019881030.051
macromolecular complex assemblyGO:00650032560.050
regulation of defense responseGO:00313471020.050
positive regulation of peptidase activityGO:0010952290.049
intracellular transportGO:00469072280.048
positive regulation of cellular biosynthetic processGO:00313283160.047
regulation of proteolysisGO:0030162870.046
regulation of immune system processGO:00026821760.045
apoptotic signaling pathwayGO:0097190270.045
positive regulation of cell communicationGO:00106472500.043
activation of cysteine type endopeptidase activityGO:0097202170.043
positive regulation of response to stimulusGO:00485843230.043
enzyme linked receptor protein signaling pathwayGO:00071671790.042
columnar cuboidal epithelial cell developmentGO:00020662490.042
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.041
negative regulation of nitrogen compound metabolic processGO:00511722650.041
positive regulation of apoptotic processGO:0043065470.040
response to alcoholGO:0097305950.040
macromolecule catabolic processGO:00090571610.040
regulation of cellular protein metabolic processGO:00322682430.039
epithelial cell differentiationGO:00308553220.039
Fly
brain developmentGO:00074201200.039
immune responseGO:00069552460.038
regulation of cellular catabolic processGO:00313291570.037
response to oxygen containing compoundGO:19017002000.037
regulation of autophagyGO:0010506620.037
developmental growthGO:00485892800.037
protein processingGO:0016485680.037
Human Mouse
protein modification processGO:00362114380.036
positive regulation of protein metabolic processGO:00512471280.036
regulation of molecular functionGO:00650092170.036
negative regulation of cell cycleGO:00457861160.036
protein localizationGO:00081042840.036
autophagic cell deathGO:0048102830.035
response to nutrient levelsGO:00316671140.035
positive regulation of programmed cell deathGO:0043068620.035
lipid metabolic processGO:00066291210.034
regulation of catabolic processGO:00098941700.034
response to hypoxiaGO:0001666530.034
membrane organizationGO:00610241120.034
secretionGO:00469031090.033
response to extracellular stimulusGO:00099911160.033
positive regulation of endopeptidase activityGO:0010950260.033
cellular response to starvationGO:0009267610.033
protein transportGO:00150311550.033
imaginal disc derived wing morphogenesisGO:00074763370.032
Fly
chromosome organizationGO:00512763600.032
vesicle mediated transportGO:00161923810.031
response to endogenous stimulusGO:00097191190.031
Mouse
negative regulation of cellular metabolic processGO:00313243820.031
imaginal disc derived appendage developmentGO:00487373990.031
Fly
humoral immune responseGO:00069591170.030
cellular cation homeostasisGO:0030003380.030
cellular transition metal ion homeostasisGO:004691690.030
negative regulation of cell proliferationGO:0008285690.029
cellular amide metabolic processGO:0043603800.029
Human Mouse
central nervous system developmentGO:00074172010.029
small molecule metabolic processGO:00442813050.029
nitrogen compound transportGO:0071705850.029
response to metal ionGO:0010038230.028
spermatid developmentGO:0007286980.028
multicellular organismal homeostasisGO:0048871410.028
Human
cellular modified amino acid metabolic processGO:0006575450.028
negative regulation of cell communicationGO:00106482230.028
regulation of cell differentiationGO:00455953020.027
positive regulation of proteolysisGO:0045862520.027
positive regulation of nitrogen compound metabolic processGO:00511733540.027
anatomical structure homeostasisGO:0060249970.027
Human
carbohydrate metabolic processGO:0005975820.027
regulation of dna metabolic processGO:0051052340.027
sperm individualizationGO:0007291480.027
columnar cuboidal epithelial cell differentiationGO:00020652560.026
Fly
response to starvationGO:0042594970.026
homeostatic processGO:00425921990.026
Human
nucleobase containing compound transportGO:0015931560.026
posttranscriptional regulation of gene expressionGO:00106081450.025
regionalizationGO:00030024160.025
regulation of cellular ketone metabolic processGO:001056530.025
negative regulation of programmed cell deathGO:0043069720.025
regulation of transportGO:00510491810.025
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.025
positive regulation of catabolic processGO:00098961050.025
endomembrane system organizationGO:00102561190.024
execution phase of apoptosisGO:009719470.024
male sex differentiationGO:0046661250.023
Mouse
regulation of catalytic activityGO:00507901850.023
negative regulation of protein metabolic processGO:0051248850.023
organelle membrane fusionGO:0090174160.023
striated muscle tissue developmentGO:0014706270.023
negative regulation of nucleobase containing compound metabolic processGO:00459342610.023
positive regulation of cysteine type endopeptidase activityGO:2001056240.023
positive regulation of rna metabolic processGO:00512542710.023
cellular homeostasisGO:0019725800.023
regulation of phosphorus metabolic processGO:00511742100.023
Human
metal ion homeostasisGO:0055065440.022
positive regulation of apoptotic signaling pathwayGO:200123540.022
positive regulation of hydrolase activityGO:0051345780.022
membrane fusionGO:0061025420.022
digestive system developmentGO:00551231490.022
reproductive structure developmentGO:0048608740.022
Mouse
response to biotic stimulusGO:00096072940.022
negative regulation of apoptotic processGO:0043066630.021
positive regulation of autophagyGO:0010508210.021
phagocytosisGO:00069092150.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.021
negative regulation of cellular protein metabolic processGO:0032269850.021
cellularizationGO:0007349900.021
positive regulation of nucleic acid templated transcriptionGO:19035082660.021
defense response to other organismGO:00985422250.021
immune response regulating signaling pathwayGO:000276420.021
circulatory system developmentGO:0072359820.020
positive regulation of rna biosynthetic processGO:19026802660.020
positive regulation of signal transductionGO:00099672230.020
locomotory behaviorGO:00076261760.020
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.020
negative regulation of cell cycle processGO:00109481090.020
organelle assemblyGO:00709251980.020
regulation of transcription from rna polymerase ii promoterGO:00063573780.020
post embryonic appendage morphogenesisGO:00351203850.020
Fly
regulation of mitotic cell cycle phase transitionGO:19019901300.019
immune response activating signal transductionGO:000275720.019
negative regulation of signal transductionGO:00099682060.019
endocytosisGO:00068973100.019
cell cell signaling involved in cell fate commitmentGO:00451682100.019
protein secretionGO:0009306450.019
positive regulation of signalingGO:00230562430.019
regulation of innate immune responseGO:0045088710.019
positive regulation of transportGO:0051050920.018
response to temperature stimulusGO:00092661060.018
positive regulation of defense responseGO:0031349590.018
response to ionizing radiationGO:0010212320.018
regulation of gene expression epigeneticGO:00400291280.018
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.018
mitotic cell cycle phase transitionGO:00447721380.018
cellular response to abiotic stimulusGO:0071214580.018
spermatid differentiationGO:00485151140.018
response to radiationGO:00093141550.018
cellular amino acid metabolic processGO:0006520610.017
establishment of protein localizationGO:00451841630.017
regulation of cellular response to stressGO:0080135890.017
negative regulation of mitotic cell cycle phase transitionGO:19019911030.017
development of primary male sexual characteristicsGO:004654690.017
Mouse
negative regulation of cellular biosynthetic processGO:00313272770.017
positive regulation of transcription dna templatedGO:00458932660.017
regulation of multi organism processGO:00439001310.017
regulation of cellular localizationGO:00603411360.017
positive regulation of molecular functionGO:00440931360.017
response to nitrogen compoundGO:1901698900.017
cellular response to dna damage stimulusGO:00069742230.017
cellular protein catabolic processGO:0044257830.016
mitochondrion organizationGO:0007005650.016
mitotic dna damage checkpointGO:0044773740.016
gliogenesisGO:0042063800.016
dna metabolic processGO:00062592270.016
single organism intracellular transportGO:19025822070.016
rna transportGO:0050658460.016
cellular macromolecular complex assemblyGO:00346221530.016
negative regulation of response to stimulusGO:00485852580.016
mitotic spindle organizationGO:00070522200.016
forebrain developmentGO:003090020.016
organic substance catabolic processGO:19015753080.015
muscle structure developmentGO:00610612240.015
Zebrafish
chromatin modificationGO:00165681470.015
muscle tissue developmentGO:0060537300.015
tissue homeostasisGO:0001894360.015
Human
regulation of protein transportGO:0051223570.015
intrinsic apoptotic signaling pathwayGO:0097193160.015
response to external biotic stimulusGO:00432072930.015
positive regulation of macromolecule biosynthetic processGO:00105572830.015
chemical homeostasisGO:0048878920.014
Human
regulation of protein localizationGO:0032880760.014
single organism membrane organizationGO:0044802930.014
negative regulation of biosynthetic processGO:00098902770.014
cellular macromolecule catabolic processGO:00442651360.014
negative regulation of nucleic acid templated transcriptionGO:19035072400.014
regulation of cell cycle phase transitionGO:19019871300.014
wound healingGO:0042060750.014
positive regulation of macroautophagyGO:001623980.014
chromatin organizationGO:00063252070.014
appendage developmentGO:00487364010.013
Fly
positive regulation of canonical wnt signaling pathwayGO:009026370.013
mesenchymal cell developmentGO:001403110.013
organonitrogen compound biosynthetic processGO:19015661170.013
regulation of establishment of protein localizationGO:0070201610.013
positive regulation of gene expressionGO:00106282900.013
iron ion homeostasisGO:005507250.013
muscle organ developmentGO:00075171270.013
negative regulation of mitotic cell cycleGO:00459301090.013
oxoacid metabolic processGO:00434361030.013
single organism catabolic processGO:00447122280.013
regulation of phosphorylationGO:00423251470.013
Human
negative regulation of developmental processGO:00510932010.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.013
aromatic compound catabolic processGO:00194391660.012
centrosome cycleGO:00070981370.012
neuron deathGO:0070997270.012
energy derivation by oxidation of organic compoundsGO:0015980320.012
single organism cell adhesionGO:0098602470.012
positive regulation of i kappab kinase nf kappab signalingGO:004312310.012
response to copper ionGO:004668840.012
instar larval developmentGO:0002168550.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
regulation of cellular amine metabolic processGO:003323830.012
carboxylic acid metabolic processGO:0019752920.012
response to virusGO:0009615280.011
positive regulation of cellular protein metabolic processGO:00322701180.011
regulation of cell cycle processGO:00105641810.011
translationGO:0006412690.011
response to ethanolGO:0045471590.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.011
negative regulation of protein processingGO:0010955310.011
regulation of epithelial cell proliferationGO:005067840.011
sensory organ morphogenesisGO:00905962600.011
regulation of intracellular transportGO:0032386640.011
ameboidal type cell migrationGO:00016671510.011
cellular response to organic substanceGO:00713101320.011
Mouse
positive regulation of catalytic activityGO:00430851180.011
extrinsic apoptotic signaling pathwayGO:009719110.011
establishment of rna localizationGO:0051236470.011
cation transportGO:00068121100.011
response to woundingGO:0009611940.011
immune effector processGO:0002252980.011
regulation of developmental growthGO:00486381740.010
respiratory system developmentGO:00605412130.010
stem cell proliferationGO:0072089880.010
regulation of gtpase activityGO:0043087440.010
positive regulation of cell cycleGO:0045787430.010
body morphogenesisGO:001017120.010
biological adhesionGO:00226101380.010
regulation of retinal cell programmed cell deathGO:0046668180.010
positive regulation of phosphorus metabolic processGO:00105621390.010
negative regulation of rna metabolic processGO:00512532510.010

cathD disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.062
Human
nervous system diseaseDOID:86300.020
central nervous system diseaseDOID:33100.011
neurodegenerative diseaseDOID:128900.010