IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

RpLP0 (Dmel_CG7490)

Ribosomal protein LP0

(Aliases: Ap3,p0,P0,l(3)01544,CG7490,AP3,l(3)0154,Rplp0,RPL P0,RpPO,LP0,RpP0,Dmel\CG7490,RLA0,P35,PO,Ape)

FLYBASE: FBgn0000100
Entrez: 40451
UniProtKB: P19889
UniProtKB: M9PG76

Process Predictions
Disease Predictions

RpLP0 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic spindle elongation	GO:0000022	81	0.960
spindle elongation	GO:0051231	83	0.953
mitotic spindle organization	GO:0007052	220	0.845
spindle organization	GO:0007051	253	0.770
negative regulation of gene expression	GO:0010629	387	0.319
centrosome organization	GO:0051297	163	0.260
centrosome cycle	GO:0007098	137	0.247
programmed cell death	GO:0012501	257	0.237	Worm
death	GO:0016265	284	0.164	Worm
microtubule organizing center organization	GO:0031023	168	0.151
endocytosis	GO:0006897	310	0.136
apoptotic process	GO:0006915	159	0.134	Worm
larval development	GO:0002164	104	0.129	Worm
ribosomal large subunit biogenesis	GO:0042273	1	0.125	Yeast
vesicle mediated transport	GO:0016192	381	0.119
regulation of cell cycle	GO:0051726	291	0.116
cell death	GO:0008219	279	0.116	Worm
embryo development ending in birth or egg hatching	GO:0009792	152	0.105	Worm
gene silencing	GO:0016458	138	0.104
centrosome duplication	GO:0051298	121	0.089
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.088
determination of adult lifespan	GO:0008340	137	0.088
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.079
molting cycle	GO:0042303	56	0.077
translation	GO:0006412	69	0.074	Yeast
mitotic nuclear division	GO:0007067	213	0.074
regulation of gene expression epigenetic	GO:0040029	128	0.071
rrna processing	GO:0006364	3	0.071
negative regulation of biosynthetic process	GO:0009890	277	0.069
catabolic process	GO:0009056	409	0.069
regulation of protein metabolic process	GO:0051246	256	0.065
positive regulation of macromolecule metabolic process	GO:0010604	405	0.060
purine ribonucleoside metabolic process	GO:0046128	127	0.060
negative regulation of cellular metabolic process	GO:0031324	382	0.060
cell proliferation	GO:0008283	299	0.057
cellular catabolic process	GO:0044248	372	0.056
positive regulation of cellular biosynthetic process	GO:0031328	316	0.055
positive regulation of protein metabolic process	GO:0051247	128	0.053
cytoplasmic translation	GO:0002181	0	0.052	Yeast
positive regulation of multicellular organismal process	GO:0051240	143	0.051
maintenance of location	GO:0051235	73	0.050
protein complex assembly	GO:0006461	200	0.050
negative regulation of cellular biosynthetic process	GO:0031327	277	0.050
regulation of cellular component biogenesis	GO:0044087	201	0.048
phagocytosis	GO:0006909	215	0.048
regulation of cellular protein metabolic process	GO:0032268	243	0.046
negative regulation of signal transduction	GO:0009968	206	0.043
organelle assembly	GO:0070925	198	0.042	Yeast
phosphorylation	GO:0016310	294	0.040
protein maturation	GO:0051604	71	0.039
positive regulation of biosynthetic process	GO:0009891	316	0.038
taxis	GO:0042330	304	0.038
purine nucleoside catabolic process	GO:0006152	112	0.038
regulation of phosphorylation	GO:0042325	147	0.036
body morphogenesis	GO:0010171	2	0.035
translational elongation	GO:0006414	4	0.035
rna localization	GO:0006403	115	0.034
organic substance catabolic process	GO:1901575	308	0.034
regulation of phosphate metabolic process	GO:0019220	210	0.034
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.033
negative regulation of transcription dna templated	GO:0045892	237	0.033
meiotic cell cycle process	GO:1903046	132	0.033
proteolysis	GO:0006508	192	0.032
multicellular organismal aging	GO:0010259	140	0.032
oxoacid metabolic process	GO:0043436	103	0.031
purine ribonucleotide metabolic process	GO:0009150	145	0.031
protein modification process	GO:0036211	438	0.030
positive regulation of gene expression	GO:0010628	290	0.030
lipid localization	GO:0010876	54	0.030
gland development	GO:0048732	191	0.029
regulation of cell death	GO:0010941	173	0.029
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.029
regulation of catalytic activity	GO:0050790	185	0.028
organic acid metabolic process	GO:0006082	103	0.028
negative regulation of rna metabolic process	GO:0051253	251	0.027
cellular protein modification process	GO:0006464	438	0.027
single organism biosynthetic process	GO:0044711	206	0.027
macromolecular complex assembly	GO:0065003	256	0.026	Yeast
response to abiotic stimulus	GO:0009628	341	0.026
ribonucleoside catabolic process	GO:0042454	112	0.025
developmental growth	GO:0048589	280	0.025
response to light stimulus	GO:0009416	124	0.024
ribonucleoprotein complex biogenesis	GO:0022613	31	0.024	Yeast
response to other organism	GO:0051707	293	0.024
chromosome segregation	GO:0007059	157	0.024
purine nucleotide metabolic process	GO:0006163	146	0.024
chromatin silencing	GO:0006342	76	0.024
purine nucleoside metabolic process	GO:0042278	127	0.023
purine containing compound metabolic process	GO:0072521	155	0.023
nucleoside metabolic process	GO:0009116	127	0.023
ribonucleoside metabolic process	GO:0009119	127	0.023
dendrite development	GO:0016358	204	0.023
organonitrogen compound metabolic process	GO:1901564	318	0.023
purine ribonucleotide catabolic process	GO:0009154	109	0.022
neuron recognition	GO:0008038	101	0.022
meiotic cell cycle	GO:0051321	171	0.022
dendrite morphogenesis	GO:0048813	199	0.022
negative regulation of cell communication	GO:0010648	223	0.022
signal transduction by phosphorylation	GO:0023014	107	0.021
positive regulation of catalytic activity	GO:0043085	118	0.021
positive regulation of cellular protein metabolic process	GO:0032270	118	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.021	Yeast
ribonucleoprotein complex assembly	GO:0022618	23	0.021	Yeast
regulation of apoptotic process	GO:0042981	130	0.021
cellular response to chemical stimulus	GO:0070887	199	0.021	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	174	0.021
protein processing	GO:0016485	68	0.021
regulation of translation	GO:0006417	56	0.021
ion homeostasis	GO:0050801	55	0.021
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.020
eye development	GO:0001654	323	0.020
cell recognition	GO:0008037	102	0.020
ncrna metabolic process	GO:0034660	43	0.020
regulation of cellular amine metabolic process	GO:0033238	3	0.020
negative regulation of translation	GO:0017148	28	0.020
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.020
aging	GO:0007568	143	0.019
intracellular transport	GO:0046907	228	0.019
regulation of phosphorus metabolic process	GO:0051174	210	0.019
positive regulation of cell motility	GO:2000147	3	0.019
regulation of anatomical structure size	GO:0090066	163	0.019
posttranscriptional regulation of gene expression	GO:0010608	145	0.019
regulation of molecular function	GO:0065009	217	0.019
purine ribonucleoside catabolic process	GO:0046130	112	0.018
regulation of proteolysis	GO:0030162	87	0.018
macromolecule catabolic process	GO:0009057	161	0.018
homeostatic process	GO:0042592	199	0.018
regulation of multicellular organismal development	GO:2000026	414	0.018
fatty acid oxidation	GO:0019395	6	0.017
single organism catabolic process	GO:0044712	228	0.017
response to radiation	GO:0009314	155	0.017
single organism intracellular transport	GO:1902582	207	0.017
wnt signaling pathway	GO:0016055	98	0.017
immune system process	GO:0002376	347	0.017
chemical homeostasis	GO:0048878	92	0.017
negative regulation of cell death	GO:0060548	81	0.017
nuclear division	GO:0000280	332	0.017
establishment of rna localization	GO:0051236	47	0.017
response to endogenous stimulus	GO:0009719	119	0.016
negative regulation of nucleotide catabolic process	GO:0030812	1	0.016
positive regulation of phosphorylation	GO:0042327	87	0.016
aromatic compound catabolic process	GO:0019439	166	0.016
negative regulation of rna biosynthetic process	GO:1902679	240	0.016
nucleoside catabolic process	GO:0009164	112	0.016
regulation of programmed cell death	GO:0043067	152	0.015
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.014
cellular nitrogen compound catabolic process	GO:0044270	165	0.014
central nervous system development	GO:0007417	201	0.014
compound eye development	GO:0048749	307	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
negative regulation of apoptotic process	GO:0043066	63	0.014
modification dependent protein catabolic process	GO:0019941	78	0.014
male gamete generation	GO:0048232	201	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.013
response to external biotic stimulus	GO:0043207	293	0.013
lipid storage	GO:0019915	38	0.013
positive regulation of phosphorus metabolic process	GO:0010562	139	0.013
regulation of cell proliferation	GO:0042127	163	0.013
organic substance transport	GO:0071702	257	0.013
nucleotide metabolic process	GO:0009117	161	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.013
response to biotic stimulus	GO:0009607	294	0.013
regulation of localization	GO:0032879	275	0.013
regulation of hydrolase activity	GO:0051336	97	0.013
negative regulation of signaling	GO:0023057	219	0.013
spermatogenesis	GO:0007283	200	0.013
nuclear transport	GO:0051169	72	0.012
positive regulation of molecular function	GO:0044093	136	0.012
defense response to other organism	GO:0098542	225	0.012
developmental programmed cell death	GO:0010623	138	0.012
response to temperature stimulus	GO:0009266	106	0.012
salivary gland morphogenesis	GO:0007435	145	0.012
glycosyl compound metabolic process	GO:1901657	127	0.012
nucleosome mobilization	GO:0042766	9	0.012
cellular response to organic substance	GO:0071310	132	0.012	Mouse
biological adhesion	GO:0022610	138	0.012
positive regulation of cell communication	GO:0010647	250	0.012
chemotaxis	GO:0006935	249	0.012
cellular macromolecule catabolic process	GO:0044265	136	0.012
establishment or maintenance of cell polarity	GO:0007163	167	0.011
negative regulation of cellular protein metabolic process	GO:0032269	85	0.011
small molecule metabolic process	GO:0044281	305	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
regulation of intracellular signal transduction	GO:1902531	236	0.011
receptor mediated endocytosis	GO:0006898	21	0.011
heterocycle catabolic process	GO:0046700	166	0.011
positive regulation of cell migration	GO:0030335	2	0.011
histolysis	GO:0007559	102	0.011
positive regulation of signaling	GO:0023056	243	0.011
mapk cascade	GO:0000165	107	0.011
chromatin silencing at centromere	GO:0030702	3	0.011
negative regulation of response to stimulus	GO:0048585	258	0.011
glycosyl compound catabolic process	GO:1901658	112	0.011
hemopoiesis	GO:0030097	46	0.011
gene silencing by rna	GO:0031047	57	0.011
positive regulation of response to stimulus	GO:0048584	323	0.011
rna processing	GO:0006396	147	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.011
negative regulation of mrna processing	GO:0050686	5	0.010
tissue death	GO:0016271	102	0.010
ribonucleotide metabolic process	GO:0009259	145	0.010
ribose phosphate metabolic process	GO:0019693	145	0.010
spermatid differentiation	GO:0048515	114	0.010
regulation of multicellular organism growth	GO:0040014	40	0.010
positive regulation of developmental process	GO:0051094	143	0.010
negative regulation of programmed cell death	GO:0043069	72	0.010
regulation of mapk cascade	GO:0043408	92	0.010
protein catabolic process	GO:0030163	101	0.010
protein phosphorylation	GO:0006468	169	0.010
negative regulation of cellular component organization	GO:0051129	108	0.010

RpLP0 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.029
aplastic anemia	DOID:12449	0.021
bone marrow disease	DOID:4961	0.021
diamond blackfan anemia	DOID:1339	0.021
congenital hypoplastic anemia	DOID:1342	0.021
anemia	DOID:2355	0.021
hematopoietic system disease	DOID:74	0.021
immune system disease	DOID:2914	0.021

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