IMP: Integrative Multi-species Prediction

Drosophila melanogaster

150 known processes

zfh1 (Dmel_CG1322)

Zn finger homeodomain 1

(Aliases: zfl-1,Zfh-1,Zfh1,Zfh1a,CG1322,zfh-1,ZFH-1,Dmel\CG1322,l(3)00865,ZFH1)

Entrez: 43650
FLYBASE: FBgn0004606
UniProtKB: P28166

Process Predictions
Disease Predictions

zfh1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
tube development	GO:0035295	244	0.988	Zebrafish Mouse
embryonic organ development	GO:0048568	50	0.917	Mouse
regulation of multicellular organismal development	GO:2000026	414	0.908	Zebrafish Mouse
localization of cell	GO:0051674	257	0.889
muscle structure development	GO:0061061	224	0.887	Mouse
regulation of neurogenesis	GO:0050767	158	0.869	Mouse
axon development	GO:0061564	297	0.849
cell motility	GO:0048870	251	0.837
heart development	GO:0007507	82	0.820
regulation of cell differentiation	GO:0045595	302	0.801	Mouse
eye morphogenesis	GO:0048592	260	0.792	Mouse
muscle cell differentiation	GO:0042692	103	0.772	Mouse
cardiac cell fate commitment	GO:0060911	17	0.770
neuron projection guidance	GO:0097485	241	0.758
regulation of nervous system development	GO:0051960	248	0.708	Mouse
circulatory system development	GO:0072359	82	0.705
motor neuron axon guidance	GO:0008045	58	0.688
mesoderm development	GO:0007498	78	0.683
myoblast fusion	GO:0007520	43	0.682
cardioblast differentiation	GO:0010002	20	0.667
embryonic heart tube development	GO:0035050	22	0.658
eye development	GO:0001654	323	0.606	Mouse
cell migration	GO:0016477	238	0.554
cardiovascular system development	GO:0072358	82	0.543
salivary gland development	GO:0007431	162	0.515
cardiocyte differentiation	GO:0035051	29	0.497
respiratory system development	GO:0060541	213	0.483
positive regulation of multicellular organismal process	GO:0051240	143	0.476	Mouse
lateral inhibition	GO:0046331	206	0.474
regulation of muscle cell differentiation	GO:0051147	8	0.470	Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.458
germ cell migration	GO:0008354	43	0.454
gland development	GO:0048732	191	0.443
negative regulation of transcription dna templated	GO:0045892	237	0.435
stem cell differentiation	GO:0048863	117	0.434	Zebrafish Mouse
regulation of neuron differentiation	GO:0045664	103	0.421	Mouse
gland morphogenesis	GO:0022612	145	0.418
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.417
substrate dependent cell migration	GO:0006929	3	0.413
glial cell migration	GO:0008347	31	0.395
sensory organ morphogenesis	GO:0090596	260	0.393	Mouse
positive regulation of cell differentiation	GO:0045597	64	0.393	Mouse
cellular response to dna damage stimulus	GO:0006974	223	0.391
axon guidance	GO:0007411	233	0.389
negative regulation of cellular metabolic process	GO:0031324	382	0.386
multi organism behavior	GO:0051705	175	0.382
myotube differentiation	GO:0014902	46	0.380
epithelial cell migration open tracheal system	GO:0007427	32	0.379
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.379	Zebrafish
male gamete generation	GO:0048232	201	0.367
cardioblast cell fate commitment	GO:0042684	14	0.354
immune system development	GO:0002520	57	0.345
nephrocyte differentiation	GO:0061319	12	0.341
positive regulation of cell projection organization	GO:0031346	29	0.339
regulation of immune system process	GO:0002682	176	0.321	Mouse
hematopoietic or lymphoid organ development	GO:0048534	57	0.302
cellular amino acid metabolic process	GO:0006520	61	0.300
syncytium formation	GO:0006949	43	0.295
organonitrogen compound metabolic process	GO:1901564	318	0.293
cell projection assembly	GO:0030031	94	0.290
salivary gland morphogenesis	GO:0007435	145	0.289
positive regulation of response to stimulus	GO:0048584	323	0.285	Mouse
immune response	GO:0006955	246	0.282
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.278
mesenchyme development	GO:0060485	9	0.278	Zebrafish Mouse
axon midline choice point recognition	GO:0016199	26	0.276
positive regulation of developmental process	GO:0051094	143	0.276	Mouse
neurological system process	GO:0050877	358	0.274
reproductive structure development	GO:0048608	74	0.271
muscle tissue development	GO:0060537	30	0.259
epithelial tube morphogenesis	GO:0060562	88	0.258	Mouse
cell division	GO:0051301	248	0.254
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.249	Mouse
positive regulation of molecular function	GO:0044093	136	0.245	Mouse
regulation of anatomical structure morphogenesis	GO:0022603	242	0.241	Zebrafish
malpighian tubule development	GO:0072002	64	0.240
positive regulation of cell migration	GO:0030335	2	0.239
negative regulation of signaling	GO:0023057	219	0.238	Zebrafish
reproductive system development	GO:0061458	74	0.237
syncytium formation by plasma membrane fusion	GO:0000768	43	0.230
morphogenesis of a polarized epithelium	GO:0001738	93	0.229
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.226	Zebrafish Mouse
sex differentiation	GO:0007548	81	0.216
kidney epithelium development	GO:0072073	3	0.214
exocrine system development	GO:0035272	162	0.210
cell fate specification	GO:0001708	71	0.210
pericardial nephrocyte differentiation	GO:0061320	9	0.209
regulation of protein kinase activity	GO:0045859	51	0.205	Mouse
negative regulation of biosynthetic process	GO:0009890	277	0.205
single organism behavior	GO:0044708	391	0.199
axonogenesis	GO:0007409	290	0.198
compound eye development	GO:0048749	307	0.197
hemocyte differentiation	GO:0042386	38	0.197
negative regulation of rna metabolic process	GO:0051253	251	0.196
establishment of localization in cell	GO:0051649	402	0.193
purine nucleoside metabolic process	GO:0042278	127	0.192
nucleoside metabolic process	GO:0009116	127	0.191
regulation of organ morphogenesis	GO:2000027	78	0.189
kidney development	GO:0001822	3	0.187
urogenital system development	GO:0001655	72	0.186
gonad development	GO:0008406	50	0.182
regulation of cell proliferation	GO:0042127	163	0.180	Mouse
death	GO:0016265	284	0.180
endocytosis	GO:0006897	310	0.179
cardiac cell fate specification	GO:0060912	10	0.179
positive regulation of cell motility	GO:2000147	3	0.179
regulation of cell fate commitment	GO:0010453	29	0.178
regulation of cellular amine metabolic process	GO:0033238	3	0.176
spermatogenesis	GO:0007283	200	0.173
small molecule metabolic process	GO:0044281	305	0.173
morphogenesis of an epithelium	GO:0002009	276	0.172	Zebrafish Mouse
positive regulation of cell communication	GO:0010647	250	0.171	Mouse
actin cytoskeleton organization	GO:0030036	206	0.169
border follicle cell migration	GO:0007298	113	0.167
positive regulation of signal transduction	GO:0009967	223	0.165	Mouse
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.165
extracellular matrix organization	GO:0030198	32	0.162
hindgut development	GO:0061525	58	0.162
central nervous system development	GO:0007417	201	0.158	Mouse Rat
forebrain development	GO:0030900	2	0.158	Mouse Rat
gliogenesis	GO:0042063	80	0.158
positive regulation of cellular component biogenesis	GO:0044089	80	0.157
positive regulation of cell development	GO:0010720	61	0.157	Mouse
lymph gland development	GO:0048542	28	0.157
regulation of cardioblast differentiation	GO:0051890	9	0.156
cellular protein modification process	GO:0006464	438	0.155	Mouse
renal tubule development	GO:0061326	64	0.155
positive regulation of signaling	GO:0023056	243	0.155	Mouse
response to biotic stimulus	GO:0009607	294	0.154
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.154
amine metabolic process	GO:0009308	12	0.154
nucleobase containing small molecule metabolic process	GO:0055086	174	0.154
regulation of myotube differentiation	GO:0010830	6	0.152
camera type eye development	GO:0043010	4	0.152	Mouse
hemopoiesis	GO:0030097	46	0.151	Mouse
purine ribonucleotide metabolic process	GO:0009150	145	0.150
purine ribonucleotide catabolic process	GO:0009154	109	0.150
negative regulation of gene expression	GO:0010629	387	0.147
cell proliferation	GO:0008283	299	0.143	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.143
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.142
malpighian tubule morphogenesis	GO:0007443	44	0.142
organophosphate metabolic process	GO:0019637	195	0.140
regulation of epithelial cell migration open tracheal system	GO:2000274	11	0.138
compound eye photoreceptor cell differentiation	GO:0001751	140	0.136
heart process	GO:0003015	37	0.136
response to abiotic stimulus	GO:0009628	341	0.135
dendrite development	GO:0016358	204	0.135
regulation of response to external stimulus	GO:0032101	115	0.134
renal system process	GO:0003014	12	0.133
immune system process	GO:0002376	347	0.133
extracellular structure organization	GO:0043062	46	0.131
positive regulation of neurogenesis	GO:0050769	41	0.130	Mouse
regulation of cell shape	GO:0008360	113	0.129
semaphorin plexin signaling pathway	GO:0071526	4	0.128
response to organic substance	GO:0010033	284	0.127	Zebrafish Mouse Rat
regulation of notch signaling pathway	GO:0008593	100	0.127
brain development	GO:0007420	120	0.127	Mouse Rat
regulation of cell division	GO:0051302	72	0.126
striated muscle cell differentiation	GO:0051146	90	0.126
regulation of cellular ketone metabolic process	GO:0010565	3	0.126
regulation of lipid kinase activity	GO:0043550	2	0.125
purine nucleoside catabolic process	GO:0006152	112	0.125
negative regulation of cellular biosynthetic process	GO:0031327	277	0.125
morphogenesis of embryonic epithelium	GO:0016331	94	0.124	Mouse
regulation of response to wounding	GO:1903034	19	0.122
mapk cascade	GO:0000165	107	0.121	Mouse
regulation of cellular component biogenesis	GO:0044087	201	0.120
negative regulation of cell communication	GO:0010648	223	0.119	Zebrafish
positive regulation of nervous system development	GO:0051962	69	0.117	Mouse
open tracheal system development	GO:0007424	204	0.117
embryonic pattern specification	GO:0009880	174	0.116
nucleoside triphosphate metabolic process	GO:0009141	120	0.116
positive regulation of phosphorylation	GO:0042327	87	0.115	Mouse
positive regulation of endopeptidase activity	GO:0010950	26	0.114
regulation of cell cycle process	GO:0010564	181	0.113
spermatid development	GO:0007286	98	0.112
nephron epithelium development	GO:0072009	3	0.111
regulation of stem cell differentiation	GO:2000736	14	0.111
photoreceptor cell differentiation	GO:0046530	170	0.110
peptidyl lysine acetylation	GO:0018394	39	0.108
neuroblast fate determination	GO:0007400	12	0.107
negative regulation of signal transduction	GO:0009968	206	0.107	Zebrafish
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.107
muscle organ development	GO:0007517	127	0.105
myotube cell development	GO:0014904	3	0.105
cellular response to chemical stimulus	GO:0070887	199	0.104	Zebrafish Mouse Rat
embryonic organ morphogenesis	GO:0048562	5	0.104	Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.104
regulation of cell cycle	GO:0051726	291	0.104
development of primary sexual characteristics	GO:0045137	50	0.103
regulation of developmental growth	GO:0048638	174	0.102
ribose phosphate metabolic process	GO:0019693	145	0.101
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.101
purine containing compound metabolic process	GO:0072521	155	0.101
cardioblast cell fate determination	GO:0007510	3	0.099
regulation of cellular amino acid metabolic process	GO:0006521	0	0.099
regulation of secretion	GO:0051046	44	0.099
male courtship behavior veined wing extension	GO:0048065	22	0.097
ribonucleotide metabolic process	GO:0009259	145	0.096
regulation of epithelial cell migration	GO:0010632	12	0.093
immune response regulating signaling pathway	GO:0002764	2	0.093
regulation of immune response	GO:0050776	118	0.093
purine nucleotide catabolic process	GO:0006195	109	0.092
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.092
regulation of cell projection organization	GO:0031344	92	0.090
regulation of catalytic activity	GO:0050790	185	0.090	Mouse
regulation of muscle organ development	GO:0048634	13	0.089
response to wounding	GO:0009611	94	0.088
filopodium assembly	GO:0046847	33	0.088
negative regulation of cell proliferation	GO:0008285	69	0.088	Mouse
heterocycle catabolic process	GO:0046700	166	0.088
regulation of cell development	GO:0060284	215	0.087	Mouse
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.085
taxis	GO:0042330	304	0.085
digestive tract development	GO:0048565	149	0.085	Zebrafish
ameboidal type cell migration	GO:0001667	151	0.085	Zebrafish Mouse
camera type eye morphogenesis	GO:0048593	2	0.083	Mouse
larval somatic muscle development	GO:0007526	19	0.083
blastoderm segmentation	GO:0007350	159	0.083
peptidyl amino acid modification	GO:0018193	105	0.082
regulation of hydrolase activity	GO:0051336	97	0.082
humoral immune response	GO:0006959	117	0.081
negative regulation of cell differentiation	GO:0045596	143	0.081	Mouse
response to other organism	GO:0051707	293	0.081
extrinsic apoptotic signaling pathway	GO:0097191	1	0.080
post embryonic hemopoiesis	GO:0035166	17	0.080
endodermal cell differentiation	GO:0035987	3	0.080
compound eye morphogenesis	GO:0001745	249	0.079
secretion	GO:0046903	109	0.079
regulation of cell motility	GO:2000145	23	0.079	Zebrafish
erbb signaling pathway	GO:0038127	58	0.079
skeletal muscle fiber development	GO:0048741	3	0.079
negative regulation of rna biosynthetic process	GO:1902679	240	0.077
mesodermal cell differentiation	GO:0048333	7	0.077
cellular amine metabolic process	GO:0044106	12	0.077
regulation of protein phosphorylation	GO:0001932	64	0.077	Mouse
renal system development	GO:0072001	72	0.076
secretion by cell	GO:0032940	101	0.076
hindgut morphogenesis	GO:0007442	58	0.075
male courtship behavior	GO:0008049	63	0.075
regulation of cellular component movement	GO:0051270	42	0.074	Zebrafish
mesodermal cell fate commitment	GO:0001710	7	0.072
negative regulation of protein phosphorylation	GO:0001933	17	0.072
carbohydrate derivative metabolic process	GO:1901135	217	0.072
response to external biotic stimulus	GO:0043207	293	0.072
positive regulation of cellular amine metabolic process	GO:0033240	0	0.072
somatic muscle development	GO:0007525	66	0.071
regulation of intracellular signal transduction	GO:1902531	236	0.071	Mouse
regulation of epithelial cell proliferation	GO:0050678	4	0.071
retinal ganglion cell axon guidance	GO:0031290	12	0.071
positive regulation of hydrolase activity	GO:0051345	78	0.070
positive regulation of synapse assembly	GO:0051965	29	0.070
nucleotide metabolic process	GO:0009117	161	0.069
bmp signaling pathway	GO:0030509	27	0.069
sensory perception of mechanical stimulus	GO:0050954	72	0.069
regulation of phosphatidylinositol 3 kinase activity	GO:0043551	2	0.069
protein acylation	GO:0043543	42	0.069
regulation of molecular function	GO:0065009	217	0.068	Mouse
positive regulation of lipid metabolic process	GO:0045834	4	0.068
glycosyl compound catabolic process	GO:1901658	112	0.068
organic acid metabolic process	GO:0006082	103	0.068
small gtpase mediated signal transduction	GO:0007264	88	0.068
glycosyl compound metabolic process	GO:1901657	127	0.067
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.067
multicellular organismal reproductive behavior	GO:0033057	110	0.066
purine ribonucleoside metabolic process	GO:0046128	127	0.066
regulation of cellular protein metabolic process	GO:0032268	243	0.065	Mouse
positive regulation of cellular biosynthetic process	GO:0031328	316	0.065	Human Mouse Rat
phagocytosis	GO:0006909	215	0.065
positive regulation of transcription dna templated	GO:0045893	266	0.065	Human Mouse Rat
male courtship behavior veined wing generated song production	GO:0045433	20	0.064
mesodermal cell fate specification	GO:0007501	2	0.064
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.064
cortical actin cytoskeleton organization	GO:0030866	24	0.063
endodermal cell fate commitment	GO:0001711	3	0.063
gonadal mesoderm development	GO:0007506	8	0.062
negative regulation of cell fate specification	GO:0009996	15	0.061
cardioblast cell fate specification	GO:0042685	9	0.061
nucleoside phosphate catabolic process	GO:1901292	110	0.061
endoderm formation	GO:0001706	3	0.061
negative regulation of developmental process	GO:0051093	201	0.061	Mouse
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.061
visceral muscle development	GO:0007522	14	0.061
integrin mediated signaling pathway	GO:0007229	3	0.060
embryonic hindgut morphogenesis	GO:0048619	48	0.059
cellular response to organic substance	GO:0071310	132	0.059	Zebrafish Mouse Rat
cell cycle comprising mitosis without cytokinesis	GO:0033301	25	0.059
regulation of photoreceptor cell axon guidance	GO:2000289	5	0.059
regulation of anatomical structure size	GO:0090066	163	0.058
regulation of wnt signaling pathway	GO:0030111	68	0.058	Mouse
extracellular matrix disassembly	GO:0022617	4	0.058
response to fibroblast growth factor	GO:0071774	10	0.058	Zebrafish
dendrite morphogenesis	GO:0048813	199	0.057
imaginal disc derived wing morphogenesis	GO:0007476	337	0.057
cellular catabolic process	GO:0044248	372	0.056
regulation of transferase activity	GO:0051338	58	0.056	Mouse
positive regulation of transport	GO:0051050	92	0.056
regulation of neuron projection development	GO:0010975	69	0.055
regulation of transport	GO:0051049	181	0.055
telencephalon development	GO:0021537	2	0.055	Mouse
phosphorylation	GO:0016310	294	0.055	Mouse
anterior posterior pattern specification	GO:0009952	136	0.055	Zebrafish Mouse
positive regulation of cellular component organization	GO:0051130	156	0.054
negative regulation of protein modification process	GO:0031400	29	0.054
regulation of response to stress	GO:0080134	200	0.054	Mouse
organ formation	GO:0048645	39	0.054
regulation of phosphorylation	GO:0042325	147	0.054	Mouse
nephron development	GO:0072006	3	0.053
neuron death	GO:0070997	27	0.053
larval visceral muscle development	GO:0007523	9	0.053
inositol lipid mediated signaling	GO:0048017	4	0.053
notch signaling pathway	GO:0007219	120	0.053
synaptic growth at neuromuscular junction	GO:0051124	119	0.052
multi organism reproductive behavior	GO:0044705	121	0.051
positive regulation of rna metabolic process	GO:0051254	271	0.051	Human Mouse Rat
internal protein amino acid acetylation	GO:0006475	38	0.051
ovarian follicle cell migration	GO:0007297	121	0.051
synapse organization	GO:0050808	196	0.051
skeletal muscle organ development	GO:0060538	48	0.051
cell fate commitment involved in formation of primary germ layer	GO:0060795	10	0.051
lamellipodium organization	GO:0097581	21	0.050
malpighian tubule tip cell differentiation	GO:0061382	9	0.050
neuroblast fate commitment	GO:0014017	19	0.050
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.050	Human Mouse Rat
negative regulation of epithelial cell proliferation	GO:0050680	4	0.049
positive regulation of cell adhesion	GO:0045785	10	0.049
stem cell fate commitment	GO:0048865	25	0.049
organonitrogen compound catabolic process	GO:1901565	128	0.049
positive regulation of catalytic activity	GO:0043085	118	0.049	Mouse
regulation of protein serine threonine kinase activity	GO:0071900	25	0.049	Mouse
response to hexose	GO:0009746	3	0.048
nucleobase containing compound catabolic process	GO:0034655	165	0.048
muscle attachment	GO:0016203	36	0.048
regulation of protein acetylation	GO:1901983	7	0.048
protein modification process	GO:0036211	438	0.048	Mouse
negative regulation of neurogenesis	GO:0050768	53	0.048
nucleoside catabolic process	GO:0009164	112	0.048
endomembrane system organization	GO:0010256	119	0.048
response to oxygen containing compound	GO:1901700	200	0.046	Mouse
terminal region determination	GO:0007362	25	0.046
purine containing compound catabolic process	GO:0072523	112	0.046
ras protein signal transduction	GO:0007265	88	0.046
regulation of imaginal disc derived wing size	GO:0044719	20	0.046
positive regulation of erk1 and erk2 cascade	GO:0070374	36	0.045
purine nucleotide metabolic process	GO:0006163	146	0.045
negative regulation of photoreceptor cell differentiation	GO:0046533	8	0.045
neuroblast fate specification	GO:0014018	2	0.045
cellular nitrogen compound catabolic process	GO:0044270	165	0.045
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.045
nuclear division	GO:0000280	332	0.044
striated muscle cell development	GO:0055002	50	0.044
positive regulation of secretion by cell	GO:1903532	20	0.044
lamellipodium assembly	GO:0030032	21	0.044
regulation of phosphorus metabolic process	GO:0051174	210	0.043	Mouse
regulation of synapse assembly	GO:0051963	94	0.043
rna splicing	GO:0008380	83	0.043
positive regulation of phosphate metabolic process	GO:0045937	139	0.043	Mouse
regulation of cell junction assembly	GO:1901888	2	0.043
positive regulation of filopodium assembly	GO:0051491	15	0.043
determination of bilateral symmetry	GO:0009855	13	0.043
mesodermal cell migration	GO:0008078	7	0.043
regulation of peptidyl tyrosine phosphorylation	GO:0050730	10	0.043
regulation of mapk cascade	GO:0043408	92	0.042	Mouse
regulation of map kinase activity	GO:0043405	17	0.042	Mouse
embryonic axis specification	GO:0000578	107	0.042
eye photoreceptor cell differentiation	GO:0001754	145	0.042
reproductive behavior	GO:0019098	122	0.042
negative regulation of cellular protein metabolic process	GO:0032269	85	0.041
ribonucleotide catabolic process	GO:0009261	109	0.041
signal transduction in response to dna damage	GO:0042770	3	0.041
cognition	GO:0050890	141	0.041
larval lymph gland hemopoiesis	GO:0035167	17	0.041
organophosphate catabolic process	GO:0046434	112	0.041
tube morphogenesis	GO:0035239	191	0.041	Zebrafish Mouse
defense response to bacterium	GO:0042742	178	0.040
establishment of planar polarity	GO:0001736	87	0.040
limb development	GO:0060173	1	0.040
cell junction assembly	GO:0034329	42	0.040
negative regulation of phosphorylation	GO:0042326	35	0.040
positive regulation of protein secretion	GO:0050714	9	0.040
intracellular transport	GO:0046907	228	0.040
dorsal ventral axon guidance	GO:0033563	2	0.039
catabolic process	GO:0009056	409	0.039
nucleoside triphosphate catabolic process	GO:0009143	108	0.039
appendage development	GO:0048736	401	0.039
carboxylic acid metabolic process	GO:0019752	92	0.038
organelle localization	GO:0051640	148	0.038
homeostatic process	GO:0042592	199	0.038
spermatid differentiation	GO:0048515	114	0.038
digestive system development	GO:0055123	149	0.038	Zebrafish
developmental growth involved in morphogenesis	GO:0060560	65	0.038	Zebrafish
nucleoside phosphate metabolic process	GO:0006753	162	0.038
axon choice point recognition	GO:0016198	26	0.038
regulation of chemotaxis	GO:0050920	12	0.038
cardiac cell fate determination	GO:0060913	3	0.038
regulation of embryonic cell shape	GO:0016476	30	0.037
wnt signaling pathway	GO:0016055	98	0.037	Mouse
response to decreased oxygen levels	GO:0036293	58	0.037
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.037
outflow tract morphogenesis	GO:0003151	4	0.037
regulation of cell migration	GO:0030334	22	0.037
muscle cell development	GO:0055001	50	0.037
heart morphogenesis	GO:0003007	32	0.037
neuromuscular junction development	GO:0007528	149	0.037
connective tissue development	GO:0061448	3	0.037	Mouse
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.036
ribonucleoside metabolic process	GO:0009119	127	0.036
positive regulation of intracellular signal transduction	GO:1902533	116	0.036	Mouse
regulation of cell morphogenesis	GO:0022604	163	0.036
neuron fate commitment	GO:0048663	50	0.036
regulation of cell fate specification	GO:0042659	27	0.035
epithelium migration	GO:0090132	148	0.035	Mouse
head development	GO:0060322	135	0.035	Mouse Rat
response to acid chemical	GO:0001101	25	0.035	Mouse
regulation of phospholipase activity	GO:0010517	2	0.035
immune response activating signal transduction	GO:0002757	2	0.035
response to alcohol	GO:0097305	95	0.035
positive regulation of mapk cascade	GO:0043410	63	0.034	Mouse
regulation of localization	GO:0032879	275	0.034	Zebrafish
sensory perception of sound	GO:0007605	56	0.034
nucleotide catabolic process	GO:0009166	109	0.034
regulation of extracellular matrix organization	GO:1903053	4	0.034
regulation of cell size	GO:0008361	63	0.034
axon extension involved in axon guidance	GO:0048846	10	0.034
germ band shortening	GO:0007390	19	0.034
renal tubule morphogenesis	GO:0061333	44	0.034
germarium derived egg chamber formation	GO:0007293	101	0.034
apoptotic cell clearance	GO:0043277	14	0.034
purine ribonucleoside catabolic process	GO:0046130	112	0.033
canonical wnt signaling pathway	GO:0060070	21	0.033
positive regulation of ras gtpase activity	GO:0032320	36	0.033
cellular response to growth factor stimulus	GO:0071363	30	0.033	Zebrafish Mouse Rat
activation of protein kinase activity	GO:0032147	12	0.033
epithelial cell migration	GO:0010631	148	0.033	Mouse
renal filtration cell differentiation	GO:0061318	12	0.033
positive regulation of r7 cell differentiation	GO:0045678	7	0.032
branching morphogenesis of an epithelial tube	GO:0048754	45	0.032
negative regulation of cell cycle process	GO:0010948	109	0.032
neuron migration	GO:0001764	5	0.032
regulation of protein metabolic process	GO:0051246	256	0.032	Mouse
regulation of axonogenesis	GO:0050770	32	0.032
regulation of cell death	GO:0010941	173	0.032
regulation of neuron death	GO:1901214	26	0.032
mitotic nuclear division	GO:0007067	213	0.032
defense response to other organism	GO:0098542	225	0.032
defense response	GO:0006952	300	0.031
cellular response to acid chemical	GO:0071229	8	0.031	Mouse
anatomical structure homeostasis	GO:0060249	97	0.031
organelle fission	GO:0048285	340	0.031
appendage morphogenesis	GO:0035107	397	0.031
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.031	Human Mouse Rat
regionalization	GO:0003002	416	0.031	Zebrafish Mouse
initiation of dorsal closure	GO:0007392	12	0.031
long term memory	GO:0007616	62	0.031
tripartite regional subdivision	GO:0007351	103	0.031
epithelial cell proliferation	GO:0050673	15	0.031
transmembrane transport	GO:0055085	139	0.030
striated muscle tissue development	GO:0014706	27	0.030
actin filament bundle organization	GO:0061572	28	0.030
regulation of mitotic cell cycle	GO:0007346	190	0.030
blood circulation	GO:0008015	26	0.030
sarcomere organization	GO:0045214	26	0.030
axis elongation	GO:0003401	3	0.030	Zebrafish
negative regulation of response to stimulus	GO:0048585	258	0.030	Zebrafish
renal filtration	GO:0097205	7	0.029
regulation of bmp signaling pathway	GO:0030510	23	0.029
negative regulation of phosphate metabolic process	GO:0045936	45	0.029
regulation of locomotion	GO:0040012	42	0.029	Zebrafish
tissue morphogenesis	GO:0048729	297	0.029	Zebrafish Mouse
stem cell development	GO:0048864	79	0.029	Zebrafish Mouse
regulation of erk1 and erk2 cascade	GO:0070372	39	0.028
actin filament based process	GO:0030029	220	0.028
aromatic compound catabolic process	GO:0019439	166	0.028
polarized epithelial cell differentiation	GO:0030859	10	0.028
cellular component disassembly	GO:0022411	46	0.028
single organism intracellular transport	GO:1902582	207	0.028
meiotic cell cycle process	GO:1903046	132	0.028
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.027	Human Mouse Rat
regulation of cell substrate adhesion	GO:0010810	2	0.027
histone acetylation	GO:0016573	38	0.027
golgi organization	GO:0007030	66	0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.027	Mouse
regulation of protein secretion	GO:0050708	13	0.027
dna damage checkpoint	GO:0000077	78	0.027
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.027
regulation of photoreceptor cell differentiation	GO:0046532	34	0.027
parallel actin filament bundle assembly	GO:0030046	2	0.027
neuroblast differentiation	GO:0014016	29	0.027
post embryonic appendage morphogenesis	GO:0035120	385	0.027
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.027
regulation of organ formation	GO:0003156	3	0.026
positive regulation of secretion	GO:0051047	22	0.026
multi multicellular organism process	GO:0044706	123	0.026
regulation of malpighian tubule diameter	GO:0035297	3	0.026

zfh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.056	Human

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