IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Spase12 (Dmel_CG11500)

Spase 12-subunit

(Aliases: CG11500,Dmel\CG11500,CG31042)

FLYBASE: FBgn0040623
Entrez: 50096
UniProtKB: Q9VAL0

Process Predictions
Disease Predictions

Spase12 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
gland development	GO:0048732	191	0.105
epithelial cell development	GO:0002064	274	0.096
eye development	GO:0001654	323	0.094
localization of cell	GO:0051674	257	0.092
regulation of growth	GO:0040008	233	0.090
developmental growth	GO:0048589	280	0.077
sensory organ morphogenesis	GO:0090596	260	0.072
immune system process	GO:0002376	347	0.072
salivary gland development	GO:0007431	162	0.071
regulation of anatomical structure morphogenesis	GO:0022603	242	0.070
cell motility	GO:0048870	251	0.067
cellular protein modification process	GO:0006464	438	0.064
establishment of protein localization	GO:0045184	163	0.063
regulation of cell development	GO:0060284	215	0.060
vesicle mediated transport	GO:0016192	381	0.054
morphogenesis of an epithelium	GO:0002009	276	0.054
regulation of behavior	GO:0050795	75	0.053
exocrine system development	GO:0035272	162	0.053
regulation of multicellular organismal development	GO:2000026	414	0.051
organonitrogen compound metabolic process	GO:1901564	318	0.049
regulation of cell differentiation	GO:0045595	302	0.046
regionalization	GO:0003002	416	0.044
embryo development ending in birth or egg hatching	GO:0009792	152	0.040
intracellular transport	GO:0046907	228	0.040
response to other organism	GO:0051707	293	0.039
negative regulation of cell differentiation	GO:0045596	143	0.039
regulation of catalytic activity	GO:0050790	185	0.039
intracellular signal transduction	GO:0035556	300	0.037
establishment of localization in cell	GO:0051649	402	0.037
epithelial cell differentiation	GO:0030855	322	0.036
positive regulation of response to stimulus	GO:0048584	323	0.036
protein modification process	GO:0036211	438	0.036
response to bacterium	GO:0009617	198	0.035
development of primary sexual characteristics	GO:0045137	50	0.035
regulation of cell shape	GO:0008360	113	0.034
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.034
dorsal ventral pattern formation	GO:0009953	133	0.034
regulation of multi organism process	GO:0043900	131	0.033
negative regulation of multicellular organismal process	GO:0051241	142	0.032
compound eye development	GO:0048749	307	0.031
regulation of cell morphogenesis	GO:0022604	163	0.031
negative regulation of developmental process	GO:0051093	201	0.029
cellular protein localization	GO:0034613	160	0.029
muscle cell differentiation	GO:0042692	103	0.029
carbohydrate derivative biosynthetic process	GO:1901137	85	0.028
regulation of localization	GO:0032879	275	0.027
cellular catabolic process	GO:0044248	372	0.026
positive regulation of signaling	GO:0023056	243	0.026
regulation of molecular function	GO:0065009	217	0.025
negative regulation of nervous system development	GO:0051961	92	0.025
negative regulation of cellular metabolic process	GO:0031324	382	0.025
larval development	GO:0002164	104	0.025
response to organic substance	GO:0010033	284	0.024
endocytosis	GO:0006897	310	0.024
carbohydrate derivative metabolic process	GO:1901135	217	0.024
wnt signaling pathway	GO:0016055	98	0.023
positive regulation of canonical wnt signaling pathway	GO:0090263	7	0.023
response to external biotic stimulus	GO:0043207	293	0.023
regulation of anatomical structure size	GO:0090066	163	0.022
reproductive structure development	GO:0048608	74	0.022
developmental maturation	GO:0021700	172	0.021
response to biotic stimulus	GO:0009607	294	0.021
regulation of protein localization	GO:0032880	76	0.021
catabolic process	GO:0009056	409	0.020
cellular response to chemical stimulus	GO:0070887	199	0.020
nucleobase containing small molecule metabolic process	GO:0055086	174	0.020
regulation of catabolic process	GO:0009894	170	0.019
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.019
ameboidal type cell migration	GO:0001667	151	0.019
regulation of nervous system development	GO:0051960	248	0.019
protein localization	GO:0008104	284	0.019
embryonic development via the syncytial blastoderm	GO:0001700	148	0.018
embryonic morphogenesis	GO:0048598	206	0.018
wnt protein secretion	GO:0061355	5	0.018
tissue morphogenesis	GO:0048729	297	0.018
salivary gland morphogenesis	GO:0007435	145	0.018
negative regulation of cell development	GO:0010721	62	0.017
epithelial cell migration	GO:0010631	148	0.017
multi organism reproductive behavior	GO:0044705	121	0.017
negative regulation of cellular catabolic process	GO:0031330	34	0.017
transcription from rna polymerase ii promoter	GO:0006366	368	0.017
protein transport	GO:0015031	155	0.017
defense response	GO:0006952	300	0.017
digestive system development	GO:0055123	149	0.016
growth	GO:0040007	359	0.016
secretion	GO:0046903	109	0.016
cellular macromolecule localization	GO:0070727	220	0.016
positive regulation of cell communication	GO:0010647	250	0.016
peptidyl amino acid modification	GO:0018193	105	0.016
carbohydrate derivative catabolic process	GO:1901136	118	0.016
regulation of intracellular signal transduction	GO:1902531	236	0.015
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.015
negative regulation of response to stimulus	GO:0048585	258	0.015
cell migration	GO:0016477	238	0.015
regulation of cellular catabolic process	GO:0031329	157	0.015
digestive tract development	GO:0048565	149	0.015
cell death	GO:0008219	279	0.015
axis specification	GO:0009798	167	0.014
gland morphogenesis	GO:0022612	145	0.014
multicellular organismal reproductive behavior	GO:0033057	110	0.014
membrane budding	GO:0006900	4	0.014
programmed cell death	GO:0012501	257	0.014
positive regulation of intracellular signal transduction	GO:1902533	116	0.014
anatomical structure homeostasis	GO:0060249	97	0.013
cell adhesion	GO:0007155	136	0.013
digestive tract morphogenesis	GO:0048546	127	0.013
response to starvation	GO:0042594	97	0.013
positive regulation of signal transduction	GO:0009967	223	0.012
death	GO:0016265	284	0.012
reproductive system development	GO:0061458	74	0.012
intracellular protein transport	GO:0006886	104	0.012
regulation of reproductive process	GO:2000241	54	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
compound eye morphogenesis	GO:0001745	249	0.012
negative regulation of rna metabolic process	GO:0051253	251	0.012
centrosome cycle	GO:0007098	137	0.012
organic substance transport	GO:0071702	257	0.012
oocyte construction	GO:0007308	112	0.012
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.011
reproductive behavior	GO:0019098	122	0.011
autophagy	GO:0006914	108	0.011
regulation of phosphatase activity	GO:0010921	3	0.011
regulation of oviposition	GO:0046662	14	0.011
multi multicellular organism process	GO:0044706	123	0.011
spermatogenesis	GO:0007283	200	0.011
cellular amine metabolic process	GO:0044106	12	0.011
regulation of cellular localization	GO:0060341	136	0.010
base excision repair	GO:0006284	2	0.010
peptidyl serine modification	GO:0018209	7	0.010
regulation of cellular component size	GO:0032535	98	0.010
gastrulation	GO:0007369	70	0.010

Spase12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
acquired metabolic disease	DOID:0060158	0.012
amyloidosis	DOID:9120	0.012
familial visceral amyloidosis	DOID:0050636	0.012
disease of metabolism	DOID:0014667	0.012

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network