Drosophila melanogaster

70 known processes

Sin1 (Dmel_CG10105)

SAPK-interacting protein 1

(Aliases: CG10105,dSin1,Dmel\CG10105,sin1)

Sin1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dendrite developmentGO:00163582040.964
dendrite morphogenesisGO:00488131990.947
male gamete generationGO:00482322010.397
regulation of transcription from rna polymerase ii promoterGO:00063573780.381
transcription from rna polymerase ii promoterGO:00063663680.372
negative regulation of macromolecule biosynthetic processGO:00105582700.352
regulation of dendrite morphogenesisGO:0048814280.329
response to bacteriumGO:00096171980.311
negative regulation of transcription dna templatedGO:00458922370.298
sensory organ morphogenesisGO:00905962600.255
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.252
negative regulation of nitrogen compound metabolic processGO:00511722650.250
regulation of cell differentiationGO:00455953020.247
positive regulation of nitrogen compound metabolic processGO:00511733540.245
positive regulation of rna biosynthetic processGO:19026802660.240
stem cell differentiationGO:00488631170.232
localization of cellGO:00516742570.230
negative regulation of cellular biosynthetic processGO:00313272770.230
negative regulation of cell differentiationGO:00455961430.220
spermatogenesisGO:00072832000.215
regulation of multicellular organismal developmentGO:20000264140.212
gland developmentGO:00487321910.208
positive regulation of transcription dna templatedGO:00458932660.206
cell motilityGO:00488702510.205
stem cell developmentGO:0048864790.186
respiratory system developmentGO:00605412130.185
cellular response to starvationGO:0009267610.179
regulation of dendrite developmentGO:0050773370.177
negative regulation of rna metabolic processGO:00512532510.175
positive regulation of gene expressionGO:00106282900.164
cellular response to extracellular stimulusGO:0031668640.163
enzyme linked receptor protein signaling pathwayGO:00071671790.160
positive regulation of macromolecule metabolic processGO:00106044050.152
negative regulation of biosynthetic processGO:00098902770.146
epithelial tube morphogenesisGO:0060562880.145
cellular response to dna damage stimulusGO:00069742230.144
protein modification processGO:00362114380.140
negative regulation of nucleic acid templated transcriptionGO:19035072400.139
tissue morphogenesisGO:00487292970.135
negative regulation of gene expressionGO:00106293870.129
neuron recognitionGO:00080381010.129
morphogenesis of an epitheliumGO:00020092760.122
negative regulation of nucleobase containing compound metabolic processGO:00459342610.120
negative regulation of developmental processGO:00510932010.118
tube developmentGO:00352952440.110
morphogenesis of a polarized epitheliumGO:0001738930.110
hair cell differentiationGO:0035315470.102
negative regulation of rna biosynthetic processGO:19026792400.101
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.099
positive regulation of rna metabolic processGO:00512542710.096
nuclear divisionGO:00002803320.091
cellular catabolic processGO:00442483720.090
cellular protein modification processGO:00064644380.089
negative regulation of cellular metabolic processGO:00313243820.089
regulation of cell developmentGO:00602842150.089
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.089
fat soluble vitamin biosynthetic processGO:004236210.089
tube morphogenesisGO:00352391910.088
epithelial cell differentiationGO:00308553220.085
cell migrationGO:00164772380.083
negative regulation of cell communicationGO:00106482230.081
positive regulation of response to stimulusGO:00485843230.080
establishment or maintenance of cell polarityGO:00071631670.080
muscle cell differentiationGO:00426921030.077
homeostatic processGO:00425921990.074
lipid homeostasisGO:0055088330.073
response to biotic stimulusGO:00096072940.072
appendage developmentGO:00487364010.070
spermatid developmentGO:0007286980.070
imaginal disc derived appendage developmentGO:00487373990.069
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.069
cellular response to nutrient levelsGO:0031669620.069
positive regulation of nucleobase containing compound metabolic processGO:00459353320.068
regulation of anatomical structure sizeGO:00900661630.068
response to extracellular stimulusGO:00099911160.067
positive regulation of nucleic acid templated transcriptionGO:19035082660.067
cellular response to external stimulusGO:0071496660.066
cell recognitionGO:00080371020.064
catabolic processGO:00090564090.063
circulatory system processGO:0003013370.063
positive regulation of macromolecule biosynthetic processGO:00105572830.062
appendage morphogenesisGO:00351073970.062
regulation of cellular component sizeGO:0032535980.062
regulation of cell morphogenesis involved in differentiationGO:0010769610.062
detection of stimulusGO:00516061560.060
organic substance catabolic processGO:19015753080.060
positive regulation of biosynthetic processGO:00098913160.060
blood circulationGO:0008015260.059
response to organic substanceGO:00100332840.058
regulation of neurogenesisGO:00507671580.058
forebrain developmentGO:003090020.058
regulation of neuron projection developmentGO:0010975690.056
regionalizationGO:00030024160.056
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.056
ameboidal type cell migrationGO:00016671510.055
positive regulation of cellular biosynthetic processGO:00313283160.054
negative regulation of multicellular organismal processGO:00512411420.053
negative regulation of response to stimulusGO:00485852580.053
imaginal disc derived appendage morphogenesisGO:00351143950.052
muscle organ developmentGO:00075171270.051
response to other organismGO:00517072930.051
epithelium migrationGO:00901321480.050
skin developmentGO:0043588650.048
regulation of anatomical structure morphogenesisGO:00226032420.048
developmental growthGO:00485892800.048
cellular ketone metabolic processGO:0042180240.047
negative regulation of signal transductionGO:00099682060.047
cellular macromolecular complex assemblyGO:00346221530.047
open tracheal system developmentGO:00074242040.046
camera type eye developmentGO:004301040.045
camera type eye morphogenesisGO:004859320.044
negative regulation of signalingGO:00230572190.044
regulation of nervous system developmentGO:00519602480.043
regulation of localizationGO:00328792750.043
single organism catabolic processGO:00447122280.042
regulation of cell sizeGO:0008361630.042
proteolysisGO:00065081920.042
regulation of cell projection organizationGO:0031344920.041
exocrine system developmentGO:00352721620.041
organic acid metabolic processGO:00060821030.040
maintenance of locationGO:0051235730.040
Worm
response to abiotic stimulusGO:00096283410.039
spermatid differentiationGO:00485151140.039
positive regulation of signal transductionGO:00099672230.039
chromatin organizationGO:00063252070.038
mitotic spindle organizationGO:00070522200.038
chromosome organizationGO:00512763600.038
ion transmembrane transportGO:00342201220.038
response to fungusGO:0009620500.037
post embryonic appendage morphogenesisGO:00351203850.037
stem cell proliferationGO:0072089880.036
response to lipopolysaccharideGO:003249640.035
positive regulation of multicellular organismal processGO:00512401430.034
salivary gland developmentGO:00074311620.034
positive regulation of signalingGO:00230562430.034
regulation of rac protein signal transductionGO:003502030.034
positive regulation of cell communicationGO:00106472500.034
intracellular signal transductionGO:00355563000.034
tor signalingGO:0031929320.033
organelle fissionGO:00482853400.033
cellular response to organic substanceGO:00713101320.033
regulation of wnt signaling pathwayGO:0030111680.032
sterol homeostasisGO:005509240.032
regulation of notch signaling pathwayGO:00085931000.032
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.032
positive regulation of wnt signaling pathwayGO:0030177250.032
cation transportGO:00068121100.031
regulation of organelle organizationGO:00330431960.031
retina development in camera type eyeGO:006004140.031
purine ribonucleotide metabolic processGO:00091501450.031
small molecule metabolic processGO:00442813050.031
axon developmentGO:00615642970.031
purine ribonucleoside metabolic processGO:00461281270.031
response to woundingGO:0009611940.030
neuromuscular junction developmentGO:00075281490.030
regulation of microtubule depolymerizationGO:0031114240.030
eye developmentGO:00016543230.030
head developmentGO:00603221350.030
positive regulation of cellular amino acid metabolic processGO:004576400.030
regulation of cellular amine metabolic processGO:003323830.030
response to endogenous stimulusGO:00097191190.029
macromolecular complex assemblyGO:00650032560.029
steroid catabolic processGO:000670610.029
regulation of cell morphogenesisGO:00226041630.028
purine containing compound metabolic processGO:00725211550.028
regulation of cellular ketone metabolic processGO:001056530.028
cytokinetic cell separationGO:000092010.028
ketone biosynthetic processGO:0042181160.028
defense response to other organismGO:00985422250.027
carbohydrate derivative metabolic processGO:19011352170.027
small gtpase mediated signal transductionGO:0007264880.027
central nervous system developmentGO:00074172010.027
purine nucleoside metabolic processGO:00422781270.026
regulation of catabolic processGO:00098941700.026
digestive tract morphogenesisGO:00485461270.026
synapse assemblyGO:00074161430.026
response to nutrient levelsGO:00316671140.026
non sensory hair organizationGO:0035316470.026
connective tissue developmentGO:006144830.026
cell divisionGO:00513012480.026
wing disc morphogenesisGO:00074723440.025
synapse organizationGO:00508081960.025
organonitrogen compound catabolic processGO:19015651280.025
regulation of protein metabolic processGO:00512462560.025
actin filament based processGO:00300292200.025
lipid storageGO:0019915380.025
Worm
imaginal disc derived wing morphogenesisGO:00074763370.025
anion homeostasisGO:005508130.025
fat soluble vitamin metabolic processGO:000677510.025
inter male aggressive behaviorGO:0002121600.025
positive regulation of cellular amine metabolic processGO:003324000.025
organonitrogen compound metabolic processGO:19015643180.024
response to lipidGO:0033993380.024
cell projection assemblyGO:0030031940.024
regulation of cellular component biogenesisGO:00440872010.024
nucleotide metabolic processGO:00091171610.024
kidney developmentGO:000182230.024
sensory perceptionGO:00076001960.024
epidermal cell differentiationGO:0009913510.023
brain developmentGO:00074201200.023
eggshell chorion assemblyGO:0007306660.023
regulation of cellular catabolic processGO:00313291570.023
regulation of rho protein signal transductionGO:0035023200.023
axonogenesisGO:00074092900.023
imaginal disc derived wing hair organizationGO:0035317450.023
ribose phosphate metabolic processGO:00196931450.023
organonitrogen compound biosynthetic processGO:19015661170.022
regulation of small gtpase mediated signal transductionGO:0051056930.022
epithelial cell migrationGO:00106311480.022
eye morphogenesisGO:00485922600.022
chemical homeostasisGO:0048878920.022
regulation of ras protein signal transductionGO:0046578930.022
regulation of neuron differentiationGO:00456641030.022
positive regulation of cellular protein metabolic processGO:00322701180.021
negative regulation of cell sizeGO:0045792190.021
regulation of synapse structure and activityGO:00508031280.021
nucleoside catabolic processGO:00091641120.021
single organism biosynthetic processGO:00447112060.021
segmentationGO:00352822070.021
establishment of cell polarityGO:0030010400.021
cuticle developmentGO:0042335860.021
carbohydrate derivative biosynthetic processGO:1901137850.020
rho protein signal transductionGO:0007266140.020
ribonucleoside catabolic processGO:00424541120.020
wound healingGO:0042060750.020
peptidyl amino acid modificationGO:00181931050.020
cellular response to chemical stimulusGO:00708871990.020
oocyte maturationGO:000155630.020
striated muscle cell developmentGO:0055002500.020
epidermis developmentGO:0008544650.019
response to organonitrogen compoundGO:0010243750.019
morphogenesis of a branching structureGO:0001763450.019
regulation of phosphate metabolic processGO:00192202100.019
purine nucleotide metabolic processGO:00061631460.019
chemotaxisGO:00069352490.019
aromatic compound catabolic processGO:00194391660.019
nucleoside metabolic processGO:00091161270.019
single organism carbohydrate metabolic processGO:0044723720.019
purine nucleoside catabolic processGO:00061521120.019
negative regulation of nervous system developmentGO:0051961920.019
negative regulation of cellular component organizationGO:00511291080.018
taxisGO:00423303040.018
cellular component assembly involved in morphogenesisGO:00109271510.018
salivary gland morphogenesisGO:00074351450.018
wnt signaling pathwayGO:0016055980.018
response to external biotic stimulusGO:00432072930.018
axon guidanceGO:00074112330.018
single organism intracellular transportGO:19025822070.018
neuroblast proliferationGO:0007405740.018
defense response to gram negative bacteriumGO:0050829940.018
regulation of cellular protein metabolic processGO:00322682430.018
regulation of intracellular signal transductionGO:19025312360.017
protein ubiquitinationGO:0016567700.017
ribonucleotide metabolic processGO:00092591450.017
aggressive behaviorGO:0002118630.017
mesenchymal cell developmentGO:001403110.017
guanosine containing compound catabolic processGO:1901069740.017
dorsal ventral pattern formationGO:00099531330.017
cell cell signaling involved in cell fate commitmentGO:00451682100.017
regulation of autophagyGO:0010506620.017
protein phosphorylationGO:00064681690.017
regulation of cell proliferationGO:00421271630.017
ubiquitin dependent protein catabolic processGO:0006511780.017
regulation of epithelial cell proliferationGO:005067840.017
cellular response to endogenous stimulusGO:0071495800.017
cellular response to oxygen containing compoundGO:1901701790.017
regulation of tube architecture open tracheal systemGO:0035152680.017
nucleoside triphosphate catabolic processGO:00091431080.016
digestive system developmentGO:00551231490.016
regulation of developmental growthGO:00486381740.016
lateral inhibitionGO:00463312060.016
striated muscle tissue developmentGO:0014706270.016
purine ribonucleotide catabolic processGO:00091541090.016
stem cell maintenanceGO:0019827670.016
response to alcoholGO:0097305950.016
leg disc developmentGO:0035218920.016
carbohydrate metabolic processGO:0005975820.016
regulation of tor signalingGO:0032006210.016
response to starvationGO:0042594970.016
tissue migrationGO:00901301550.015
positive regulation of intracellular signal transductionGO:19025331160.015
cholesterol homeostasisGO:004263230.015
ras protein signal transductionGO:0007265880.015
chaeta developmentGO:0022416970.015
response to osmotic stressGO:0006970140.015
actin polymerization or depolymerizationGO:0008154310.015
cellular amine metabolic processGO:0044106120.015
protein localizationGO:00081042840.015
purine ribonucleoside triphosphate metabolic processGO:00092051190.015
guanosine containing compound metabolic processGO:1901068740.015
actin cytoskeleton organizationGO:00300362060.015
purine ribonucleoside catabolic processGO:00461301120.015
columnar cuboidal epithelial cell developmentGO:00020662490.015
neuron fate commitmentGO:0048663500.015
glycosyl compound metabolic processGO:19016571270.015
skeletal muscle organ developmentGO:0060538480.015
establishment or maintenance of apical basal cell polarityGO:0035088340.015
mesenchymal cell differentiationGO:004876210.014
myotube cell developmentGO:001490430.014
digestive tract developmentGO:00485651490.014
regulation of cell cycleGO:00517262910.014
gastrulation involving germ band extensionGO:0010004360.014
cellular protein complex disassemblyGO:0043624350.014
dna metabolic processGO:00062592270.014
positive regulation of protein metabolic processGO:00512471280.014
meiotic nuclear divisionGO:00071261510.014
detection of stimulus involved in sensory perceptionGO:0050906920.014
gland morphogenesisGO:00226121450.014
cytokinetic processGO:0032506270.014
axis specificationGO:00097981670.014
protein depolymerizationGO:0051261310.014
cell adhesionGO:00071551360.014
purine containing compound catabolic processGO:00725231120.014
positive regulation of organelle organizationGO:0010638650.014
regulation of actin polymerization or depolymerizationGO:0008064270.014
negative regulation of epithelial cell proliferationGO:005068040.014
cellular response to hormone stimulusGO:0032870440.014
fertilizationGO:0009566260.014
nucleoside phosphate catabolic processGO:19012921100.013
leg disc morphogenesisGO:0007478800.013
chromatin assembly or disassemblyGO:0006333520.013
regulation of molecular functionGO:00650092170.013
heterochromatin organizationGO:0070828250.013
outflow tract morphogenesisGO:000315140.013
cell matrix adhesionGO:000716060.013
spinal cord developmentGO:002151010.013
vitamin metabolic processGO:000676620.013
regulation of cellular amino acid metabolic processGO:000652100.013
positive regulation of neurogenesisGO:0050769410.013
rac protein signal transductionGO:001660130.013
cellular protein complex assemblyGO:0043623710.013
germ line stem cell maintenanceGO:0030718500.013
regulation of rho gtpase activityGO:0032319200.013
cellular amino acid metabolic processGO:0006520610.013
growthGO:00400073590.013
regulation of microtubule polymerization or depolymerizationGO:0031110270.013
carbohydrate derivative catabolic processGO:19011361180.013
branching morphogenesis of an epithelial tubeGO:0048754450.013
protein complex assemblyGO:00064612000.013
ribonucleoside metabolic processGO:00091191270.013
cellular macromolecule catabolic processGO:00442651360.013
sensory perception of painGO:001923340.013
positive regulation of phosphorus metabolic processGO:00105621390.013
inorganic cation transmembrane transportGO:0098662610.013
skeletal muscle fiber developmentGO:004874130.013
cellularizationGO:0007349900.012
cellular response to transforming growth factor beta stimulusGO:0071560180.012
cellular response to water stimulusGO:007146220.012
oxoacid metabolic processGO:00434361030.012
positive regulation of dendrite morphogenesisGO:005077590.012
synaptic growth at neuromuscular junctionGO:00511241190.012
sensory organ boundary specificationGO:0008052220.012
cell proliferationGO:00082832990.012
glycoprotein biosynthetic processGO:0009101410.012
ecdysteroid biosynthetic processGO:0045456150.012
compound eye developmentGO:00487493070.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
purine ribonucleoside monophosphate metabolic processGO:0009167500.012
positive regulation of canonical wnt signaling pathwayGO:009026370.012
regulation of response to dna damage stimulusGO:2001020230.012
nucleoside phosphate metabolic processGO:00067531620.012
gliogenesisGO:0042063800.012
cellular protein catabolic processGO:0044257830.012
muscle tissue developmentGO:0060537300.012
macromolecular complex disassemblyGO:0032984370.012
regulation of synapse organizationGO:00508071100.012
gtp metabolic processGO:0046039720.012
developmental maturationGO:00217001720.012
protein catabolic processGO:00301631010.012
deathGO:00162652840.012
positive regulation of phosphorylationGO:0042327870.012
border follicle cell migrationGO:00072981130.012
convergent extensionGO:006002620.012
ribonucleoside triphosphate metabolic processGO:00091991190.011
protein complex disassemblyGO:0043241360.011
spinal cord patterningGO:002151110.011
regulation of protein depolymerizationGO:1901879270.011
notch signaling pathwayGO:00072191200.011
microtubule polymerization or depolymerizationGO:0031109390.011
glycosyl compound catabolic processGO:19016581120.011
eggshell formationGO:00307031050.011
chromatin modificationGO:00165681470.011
macromolecule catabolic processGO:00090571610.011
torso signaling pathwayGO:0008293210.011
formation of organ boundaryGO:0010160300.011
chromatin assemblyGO:0031497480.011
negative regulation of notch signaling pathwayGO:0045746410.011
amine metabolic processGO:0009308120.011
developmental pigmentationGO:0048066680.011
positive regulation of tor signalingGO:0032008130.011
cell growthGO:00160491080.011
ovarian follicle cell developmentGO:00307072480.011
positive regulation of cellular protein catabolic processGO:1903364240.011
neuron remodelingGO:0016322290.011
organophosphate metabolic processGO:00196371950.011
regulation of response to stressGO:00801342000.011
regulation of cell cycle processGO:00105641810.011
meiotic cell cycleGO:00513211710.011
sensory perception of chemical stimulusGO:00076061160.010
regulation of organ morphogenesisGO:2000027780.010
phosphorylationGO:00163102940.010
regulation of lipid metabolic processGO:0019216150.010
negative regulation of cell developmentGO:0010721620.010
purine nucleotide catabolic processGO:00061951090.010
cellular homeostasisGO:0019725800.010
negative regulation of intracellular signal transductionGO:1902532570.010
oocyte dorsal ventral axis specificationGO:0007310340.010
response to transforming growth factor betaGO:0071559180.010
multi organism behaviorGO:00517051750.010
lauric acid metabolic processGO:004825210.010
cellular carbohydrate metabolic processGO:0044262220.010
water homeostasisGO:003010430.010
regulation of proteolysisGO:0030162870.010
autophagyGO:00069141080.010
regulation of tube size open tracheal systemGO:0035151430.010
negative regulation of protein metabolic processGO:0051248850.010

Sin1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.087
respiratory system diseaseDOID:157900.019
lower respiratory tract diseaseDOID:005016100.019
bronchial diseaseDOID:117600.019
kidney diseaseDOID:55700.018
urinary system diseaseDOID:1800.018
nervous system diseaseDOID:86300.018
musculoskeletal system diseaseDOID:1700.011