Drosophila melanogaster

29 known processes

ref(2)P (Dmel_CG10360)

refractory to sigma P

(Aliases: Dmel\CG10360,ref(2)p,CG10360,ref(2)Pn,Ref(2)P,ref2p,ref(2)Po2,Ref2P,ref,Ref(2)p)

ref(2)P biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitochondrion morphogenesisGO:007058480.935
mitochondrion organizationGO:0007005650.783
spermatid developmentGO:0007286980.384
acylglycerol biosynthetic processGO:004646320.369
response to starvationGO:0042594970.350
intracellular signal transductionGO:00355563000.312
cellular protein modification processGO:00064644380.312
positive regulation of mitochondrion organizationGO:001082280.263
mitochondrial fissionGO:000026680.259
regulation of organelle organizationGO:00330431960.258
synaptic transmissionGO:00072682880.215
localization of cellGO:00516742570.209
regulation of catabolic processGO:00098941700.208
post embryonic appendage morphogenesisGO:00351203850.193
regulation of mitochondrial fissionGO:009014070.175
negative regulation of response to stimulusGO:00485852580.169
negative regulation of programmed cell deathGO:0043069720.166
apoptotic processGO:00069151590.166
imaginal disc derived appendage morphogenesisGO:00351143950.161
appendage developmentGO:00487364010.154
positive regulation of lipid metabolic processGO:004583440.154
protein modification processGO:00362114380.149
cell deathGO:00082192790.148
regulation of cell deathGO:00109411730.147
phosphorylationGO:00163102940.132
regulation of apoptotic processGO:00429811300.123
deathGO:00162652840.120
regulation of multicellular organismal developmentGO:20000264140.108
regulation of programmed cell deathGO:00430671520.107
imaginal disc derived appendage developmentGO:00487373990.106
negative regulation of cell deathGO:0060548810.103
response to nutrient levelsGO:00316671140.098
regulation of nervous system developmentGO:00519602480.095
small molecule metabolic processGO:00442813050.094
autophagyGO:00069141080.093
agingGO:00075681430.092
positive regulation of gene expressionGO:00106282900.091
intracellular transportGO:00469072280.091
nuclear divisionGO:00002803320.090
negative regulation of nitrogen compound metabolic processGO:00511722650.089
programmed cell deathGO:00125012570.088
negative regulation of apoptotic processGO:0043066630.086
organelle fissionGO:00482853400.085
spermatogenesisGO:00072832000.084
single organism membrane fusionGO:0044801420.079
neurological system processGO:00508773580.079
organelle fusionGO:0048284460.078
ubiquitin dependent protein catabolic processGO:0006511780.075
single organism biosynthetic processGO:00447112060.072
microtubule polymerization or depolymerizationGO:0031109390.071
developmental maturationGO:00217001720.071
cellular response to chemical stimulusGO:00708871990.067
oxoacid metabolic processGO:00434361030.067
cellular response to oxidative stressGO:0034599280.063
cytokinesisGO:0000910900.063
tissue migrationGO:00901301550.062
regulation of protein phosphorylationGO:0001932640.062
regulation of protein complex disassemblyGO:0043244290.061
negative regulation of cellular metabolic processGO:00313243820.061
organic substance transportGO:00717022570.059
positive regulation of organelle organizationGO:0010638650.059
negative regulation of growthGO:0045926840.059
negative regulation of cellular component organizationGO:00511291080.059
regulation of cellular amine metabolic processGO:003323830.057
regulation of mitochondrion organizationGO:0010821120.056
ribonucleoside monophosphate catabolic processGO:0009158390.055
protein transportGO:00150311550.054
lipid homeostasisGO:0055088330.054
regulation of cellular component biogenesisGO:00440872010.053
cell motilityGO:00488702510.051
single organism behaviorGO:00447083910.050
spermatid differentiationGO:00485151140.050
positive regulation of developmental processGO:00510941430.050
response to oxidative stressGO:0006979860.050
regulation of mitochondrial fusionGO:001063550.049
triglyceride biosynthetic processGO:001943220.049
actin filament organizationGO:00070151260.048
metal ion transportGO:0030001740.047
positive regulation of signalingGO:00230562430.046
nucleotide metabolic processGO:00091171610.046
negative regulation of signal transductionGO:00099682060.045
cytoskeleton dependent cytokinesisGO:0061640810.045
regulation of cellular ketone metabolic processGO:001056530.045
positive regulation of nitrogen compound metabolic processGO:00511733540.044
purine ribonucleoside triphosphate metabolic processGO:00092051190.044
developmental growthGO:00485892800.044
organonitrogen compound metabolic processGO:19015643180.044
purine nucleoside monophosphate metabolic processGO:0009126500.044
actin filament based processGO:00300292200.043
single organism cellular localizationGO:19025801800.043
multicellular organismal agingGO:00102591400.042
establishment of localization in cellGO:00516494020.042
metal ion homeostasisGO:0055065440.042
positive regulation of rna biosynthetic processGO:19026802660.042
regulation of transportGO:00510491810.042
purine nucleotide catabolic processGO:00061951090.042
ion transmembrane transportGO:00342201220.042
negative regulation of signalingGO:00230572190.041
cell migrationGO:00164772380.041
regulation of intracellular signal transductionGO:19025312360.041
forebrain developmentGO:003090020.039
regulation of molecular functionGO:00650092170.039
negative regulation of cytoskeleton organizationGO:0051494300.039
positive regulation of macromolecule metabolic processGO:00106044050.039
regulation of protein metabolic processGO:00512462560.038
cellular catabolic processGO:00442483720.038
nucleoside monophosphate metabolic processGO:0009123520.038
mitochondrion distributionGO:0048311100.037
homeostatic processGO:00425921990.037
cytoplasmic transportGO:00164821300.037
response to inorganic substanceGO:0010035440.037
cellular ketone metabolic processGO:0042180240.036
membrane organizationGO:00610241120.036
regulation of cellular localizationGO:00603411360.035
larval developmentGO:00021641040.035
telencephalon developmentGO:002153720.035
er associated ubiquitin dependent protein catabolic processGO:003043330.035
protein complex assemblyGO:00064612000.034
tissue morphogenesisGO:00487292970.034
morphogenesis of an epitheliumGO:00020092760.034
positive regulation of cellular biosynthetic processGO:00313283160.034
response to extracellular stimulusGO:00099911160.034
growthGO:00400073590.034
regulation of phosphorylationGO:00423251470.033
ion homeostasisGO:0050801550.033
regulation of mitotic cell cycleGO:00073461900.032
proteolysisGO:00065081920.032
imaginal disc derived wing morphogenesisGO:00074763370.032
muscle structure developmentGO:00610612240.032
chemical homeostasisGO:0048878920.032
protein complex disassemblyGO:0043241360.031
positive regulation of cellular component organizationGO:00511301560.031
regulation of cellular amino acid metabolic processGO:000652100.031
regulation of protein modification processGO:00313991120.030
endoplasmic reticulum organizationGO:0007029130.030
stress activated protein kinase signaling cascadeGO:0031098550.030
catabolic processGO:00090564090.030
regulation of response to oxidative stressGO:190288240.030
protein localizationGO:00081042840.029
positive regulation of signal transductionGO:00099672230.028
response to alcoholGO:0097305950.028
single organism intracellular transportGO:19025822070.028
regulation of protein depolymerizationGO:1901879270.028
regulation of localizationGO:00328792750.028
non sensory hair organizationGO:0035316470.027
negative regulation of intracellular signal transductionGO:1902532570.027
regulation of intracellular transportGO:0032386640.027
positive regulation of response to stimulusGO:00485843230.027
male gamete generationGO:00482322010.026
response to metal ionGO:0010038230.026
cell divisionGO:00513012480.026
cell proliferationGO:00082832990.026
nucleobase containing small molecule metabolic processGO:00550861740.026
organelle assemblyGO:00709251980.026
macromolecular complex assemblyGO:00650032560.026
epithelial cell migrationGO:00106311480.025
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
mitochondrial fusionGO:000805370.025
positive regulation of cellular catabolic processGO:0031331950.025
neutral lipid biosynthetic processGO:004646020.025
protein modification by small protein conjugation or removalGO:00706471060.024
ribonucleoside monophosphate metabolic processGO:0009161510.024
meiotic cell cycleGO:00513211710.024
organelle localizationGO:00516401480.024
atp metabolic processGO:0046034490.024
response to oxygen containing compoundGO:19017002000.024
neuron projection guidanceGO:00974852410.024
positive regulation of cellular component biogenesisGO:0044089800.023
regulation of proteolysisGO:0030162870.023
ribose phosphate metabolic processGO:00196931450.023
cellular protein localizationGO:00346131600.023
adult locomotory behaviorGO:0008344760.023
regionalizationGO:00030024160.022
negative regulation of nucleobase containing compound metabolic processGO:00459342610.022
purine nucleoside metabolic processGO:00422781270.022
negative regulation of organelle organizationGO:0010639560.022
positive regulation of nucleic acid templated transcriptionGO:19035082660.022
actin cytoskeleton organizationGO:00300362060.022
regulation of cell proliferationGO:00421271630.022
modification dependent macromolecule catabolic processGO:0043632790.022
carboxylic acid metabolic processGO:0019752920.021
nuclear transportGO:0051169720.021
regulation of transferase activityGO:0051338580.021
meiotic cytokinesisGO:0033206330.021
sperm mitochondrion organizationGO:003038270.021
response to biotic stimulusGO:00096072940.021
nucleoside triphosphate catabolic processGO:00091431080.021
positive regulation of transcription dna templatedGO:00458932660.021
response to abiotic stimulusGO:00096283410.021
negative regulation of rna biosynthetic processGO:19026792400.021
epithelium migrationGO:00901321480.020
mitochondrion degradationGO:000042280.020
ribonucleotide metabolic processGO:00092591450.020
organic acid metabolic processGO:00060821030.020
biological adhesionGO:00226101380.020
cell growthGO:00160491080.020
regulation of cellular catabolic processGO:00313291570.020
maintenance of locationGO:0051235730.020
regulation of cell cycleGO:00517262910.020
regulation of steroid metabolic processGO:001921820.020
axon guidanceGO:00074112330.020
cellular divalent inorganic cation homeostasisGO:0072503230.020
cellular nitrogen compound catabolic processGO:00442701650.019
taxisGO:00423303040.019
protein catabolic processGO:00301631010.019
negative regulation of phosphatase activityGO:001092330.019
positive regulation of phosphate metabolic processGO:00459371390.019
cellular response to dna damage stimulusGO:00069742230.019
secretionGO:00469031090.019
negative regulation of mitotic cell cycleGO:00459301090.019
cellular protein complex assemblyGO:0043623710.018
positive regulation of cell differentiationGO:0045597640.018
peptidyl amino acid modificationGO:00181931050.018
positive regulation of growthGO:0045927750.018
regulation of microtubule polymerization or depolymerizationGO:0031110270.018
carbohydrate derivative metabolic processGO:19011352170.018
purine ribonucleoside metabolic processGO:00461281270.018
cellular amino acid metabolic processGO:0006520610.018
wing disc morphogenesisGO:00074723440.018
glycosyl compound catabolic processGO:19016581120.017
cellular macromolecule localizationGO:00707272200.017
regulation of microtubule cytoskeleton organizationGO:0070507410.017
positive regulation of programmed cell deathGO:0043068620.017
protein modification by small protein removalGO:0070646280.017
protein complex biogenesisGO:00702712010.017
g2 dna damage checkpointGO:0031572690.017
organic substance catabolic processGO:19015753080.017
regulation of transcription from rna polymerase ii promoterGO:00063573780.017
tube morphogenesisGO:00352391910.017
connective tissue developmentGO:006144830.017
lipid biosynthetic processGO:0008610460.016
dna metabolic processGO:00062592270.016
positive regulation of biosynthetic processGO:00098913160.016
positive regulation of cellular protein metabolic processGO:00322701180.016
lipid modificationGO:0030258240.016
positive regulation of phosphorus metabolic processGO:00105621390.016
negative regulation of protein depolymerizationGO:1901880230.016
ion transportGO:00068111450.016
transcription from rna polymerase ii promoterGO:00063663680.016
actin filament based movementGO:0030048260.016
cytokinetic processGO:0032506270.016
inorganic cation transmembrane transportGO:0098662610.015
protein k48 linked ubiquitinationGO:007093630.015
macroautophagyGO:0016236420.015
regulation of cell cycle processGO:00105641810.015
cellular response to oxygen levelsGO:0071453300.015
adult behaviorGO:00305341370.015
regulation of anatomical structure sizeGO:00900661630.015
cellular amine metabolic processGO:0044106120.015
positive regulation of rna metabolic processGO:00512542710.015
regulation of chromosome organizationGO:0033044640.015
gliogenesisGO:0042063800.015
response to virusGO:0009615280.015
regulation of phosphorus metabolic processGO:00511742100.015
proteolysis involved in cellular protein catabolic processGO:0051603830.014
glycosyl compound metabolic processGO:19016571270.014
negative regulation of cell communicationGO:00106482230.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
actin mediated cell contractionGO:0070252210.014
cellular homeostasisGO:0019725800.014
meiotic nuclear divisionGO:00071261510.014
mapk cascadeGO:00001651070.014
cellular protein catabolic processGO:0044257830.014
protein localization to nucleusGO:0034504550.014
regulation of microtubule based processGO:0032886490.014
heterocycle catabolic processGO:00467001660.014
single organism catabolic processGO:00447122280.014
modification dependent protein catabolic processGO:0019941780.014
inorganic ion transmembrane transportGO:0098660730.014
purine ribonucleoside monophosphate metabolic processGO:0009167500.014
purine ribonucleotide catabolic processGO:00091541090.013
positive regulation of phosphorylationGO:0042327870.013
regulation of kinase activityGO:0043549530.013
learningGO:0007612750.013
response to toxic substanceGO:0009636220.013
establishment of protein localization to organelleGO:0072594620.013
appendage morphogenesisGO:00351073970.013
amine metabolic processGO:0009308120.013
negative regulation of cellular biosynthetic processGO:00313272770.013
muscle system processGO:0003012210.013
vesicle mediated transportGO:00161923810.013
purine containing compound metabolic processGO:00725211550.013
purine nucleotide metabolic processGO:00061631460.013
actin filament polymerizationGO:0030041270.013
endosomal transportGO:0016197440.013
epithelial cell developmentGO:00020642740.013
posttranscriptional regulation of gene expressionGO:00106081450.013
ribonucleoside catabolic processGO:00424541120.012
regulation of jnk cascadeGO:0046328400.012
regulation of phosphate metabolic processGO:00192202100.012
neuromuscular synaptic transmissionGO:0007274670.012
positive regulation of cell communicationGO:00106472500.012
nucleocytoplasmic transportGO:0006913720.012
protein polymerizationGO:0051258420.012
divalent inorganic cation homeostasisGO:0072507290.012
positive regulation of protein metabolic processGO:00512471280.012
nucleoside triphosphate metabolic processGO:00091411200.012
organic cyclic compound catabolic processGO:19013611680.012
embryo development ending in birth or egg hatchingGO:00097921520.011
body morphogenesisGO:001017120.011
reactive oxygen species metabolic processGO:0072593220.011
organophosphate metabolic processGO:00196371950.011
muscle organ developmentGO:00075171270.011
purine ribonucleotide metabolic processGO:00091501450.011
purine ribonucleoside monophosphate catabolic processGO:0009169380.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
stress activated mapk cascadeGO:0051403520.011
protein localization to organelleGO:0033365820.011
cellular macromolecular complex assemblyGO:00346221530.011
head developmentGO:00603221350.011
nucleoside metabolic processGO:00091161270.011
positive regulation of catabolic processGO:00098961050.011
nucleobase containing compound catabolic processGO:00346551650.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
atp catabolic processGO:0006200380.011
sodium ion transportGO:0006814220.010
regulation of catalytic activityGO:00507901850.010
nucleoside monophosphate catabolic processGO:0009125390.010
chemotaxisGO:00069352490.010
kidney developmentGO:000182230.010
response to copper ionGO:004668840.010
response to organic substanceGO:00100332840.010
regulation of developmental growthGO:00486381740.010
immune system processGO:00023763470.010
cellular response to monosaccharide stimulusGO:007132620.010

ref(2)P disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
synucleinopathyDOID:005089000.020
central nervous system diseaseDOID:33100.020
nervous system diseaseDOID:86300.020
neurodegenerative diseaseDOID:128900.020