IMP: Integrative Multi-species Prediction

Drosophila melanogaster

25 known processes

RpL17 (Dmel_CG3203)

Ribosomal protein L17

(Aliases: anon-EST:Posey276,Rpl17,CG3203,mRpL17,Dmel\CG3203)

Entrez: 31613
FLYBASE: FBgn0029897
UniProtKB: X2JIQ5
UniProtKB: Q9W3W8

Process Predictions
Disease Predictions

RpL17 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic spindle elongation	GO:0000022	81	0.968
spindle elongation	GO:0051231	83	0.841
rrna processing	GO:0006364	3	0.774
mitotic spindle organization	GO:0007052	220	0.680
ribosomal large subunit biogenesis	GO:0042273	1	0.609
spindle organization	GO:0007051	253	0.568
centrosome organization	GO:0051297	163	0.545
centrosome duplication	GO:0051298	121	0.543
embryo development ending in birth or egg hatching	GO:0009792	152	0.520	Worm
centrosome cycle	GO:0007098	137	0.472
death	GO:0016265	284	0.286	Worm
apoptotic process	GO:0006915	159	0.275	Worm
microtubule organizing center organization	GO:0031023	168	0.246
ribonucleoprotein complex biogenesis	GO:0022613	31	0.221
programmed cell death	GO:0012501	257	0.200	Worm
rna processing	GO:0006396	147	0.150
molting cycle	GO:0042303	56	0.145
cytoplasmic translation	GO:0002181	0	0.141	Yeast
ncrna metabolic process	GO:0034660	43	0.141
cell death	GO:0008219	279	0.126	Worm
regulation of cellular protein metabolic process	GO:0032268	243	0.119
regulation of cell cycle	GO:0051726	291	0.109
larval development	GO:0002164	104	0.094	Worm
posttranscriptional regulation of gene expression	GO:0010608	145	0.092
positive regulation of macromolecule metabolic process	GO:0010604	405	0.087
determination of adult lifespan	GO:0008340	137	0.073
vesicle mediated transport	GO:0016192	381	0.071
ribonucleoprotein complex subunit organization	GO:0071826	28	0.067
translation	GO:0006412	69	0.064	Yeast
ribonucleoprotein complex assembly	GO:0022618	23	0.056
positive regulation of cellular biosynthetic process	GO:0031328	316	0.055
ribosome biogenesis	GO:0042254	8	0.055
translational elongation	GO:0006414	4	0.051
negative regulation of cellular component organization	GO:0051129	108	0.051
endocytosis	GO:0006897	310	0.050
regulation of protein metabolic process	GO:0051246	256	0.047
cellular protein modification process	GO:0006464	438	0.043
regulation of translation	GO:0006417	56	0.041
establishment of localization in cell	GO:0051649	402	0.040
response to abiotic stimulus	GO:0009628	341	0.039
ncrna processing	GO:0034470	30	0.038
immune system process	GO:0002376	347	0.037
positive regulation of catalytic activity	GO:0043085	118	0.035
immune system development	GO:0002520	57	0.034
establishment of rna localization	GO:0051236	47	0.032
body morphogenesis	GO:0010171	2	0.031
positive regulation of gene expression	GO:0010628	290	0.030
negative regulation of gene expression	GO:0010629	387	0.030
organic substance transport	GO:0071702	257	0.029
tissue morphogenesis	GO:0048729	297	0.028
chemical homeostasis	GO:0048878	92	0.028
homeostatic process	GO:0042592	199	0.028
positive regulation of peptidase activity	GO:0010952	29	0.027
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.027
positive regulation of biosynthetic process	GO:0009891	316	0.027
multicellular organismal aging	GO:0010259	140	0.027
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.026
regulation of protein tyrosine kinase activity	GO:0061097	9	0.026
protein maturation	GO:0051604	71	0.025
single organism intracellular transport	GO:1902582	207	0.025
phagocytosis	GO:0006909	215	0.025
cellular macromolecular complex assembly	GO:0034622	153	0.025
proteolysis	GO:0006508	192	0.024
phosphorylation	GO:0016310	294	0.024
macromolecular complex assembly	GO:0065003	256	0.023
protein modification process	GO:0036211	438	0.023
nitrogen compound transport	GO:0071705	85	0.023
aging	GO:0007568	143	0.021
eye development	GO:0001654	323	0.021
cytoplasmic transport	GO:0016482	130	0.020
organelle assembly	GO:0070925	198	0.020
rna localization	GO:0006403	115	0.020
carboxylic acid metabolic process	GO:0019752	92	0.020
positive regulation of cellular protein metabolic process	GO:0032270	118	0.020
developmental growth	GO:0048589	280	0.020
central nervous system development	GO:0007417	201	0.019
protein processing	GO:0016485	68	0.019
positive regulation of molecular function	GO:0044093	136	0.019
positive regulation of protein metabolic process	GO:0051247	128	0.019
regulation of molecular function	GO:0065009	217	0.018
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.018
regulation of catalytic activity	GO:0050790	185	0.018
regulation of cell death	GO:0010941	173	0.018
response to external biotic stimulus	GO:0043207	293	0.018
regulation of cellular amino acid metabolic process	GO:0006521	0	0.017
positive regulation of phosphorus metabolic process	GO:0010562	139	0.017
salivary gland development	GO:0007431	162	0.017
negative regulation of cellular metabolic process	GO:0031324	382	0.017
response to organic substance	GO:0010033	284	0.017
response to other organism	GO:0051707	293	0.016
hemopoiesis	GO:0030097	46	0.016
sex differentiation	GO:0007548	81	0.016
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.016
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.016
regulation of cellular amine metabolic process	GO:0033238	3	0.016
positive regulation of phosphate metabolic process	GO:0045937	139	0.015
regulation of transport	GO:0051049	181	0.015
positive regulation of phosphorylation	GO:0042327	87	0.015
cell proliferation	GO:0008283	299	0.015
intracellular transport	GO:0046907	228	0.015
small molecule metabolic process	GO:0044281	305	0.014
positive regulation of cell communication	GO:0010647	250	0.014
regulation of localization	GO:0032879	275	0.014
meiotic cell cycle process	GO:1903046	132	0.014
negative regulation of neuron death	GO:1901215	18	0.014
nuclear transport	GO:0051169	72	0.014
locomotory behavior	GO:0007626	176	0.014
regulation of phosphorus metabolic process	GO:0051174	210	0.014
response to biotic stimulus	GO:0009607	294	0.014
cell adhesion	GO:0007155	136	0.014
positive regulation of cell migration	GO:0030335	2	0.014
positive regulation of hydrolase activity	GO:0051345	78	0.013
ion homeostasis	GO:0050801	55	0.013
regulation of catabolic process	GO:0009894	170	0.013
regulation of phosphate metabolic process	GO:0019220	210	0.013
response to monosaccharide	GO:0034284	4	0.013
secretion by cell	GO:0032940	101	0.013
negative regulation of protein tyrosine kinase activity	GO:0061099	5	0.013
innate immune response	GO:0045087	144	0.013
positive regulation of proteolysis	GO:0045862	52	0.013
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.013
nuclear export	GO:0051168	24	0.013
regulation of apoptotic process	GO:0042981	130	0.013
protein localization	GO:0008104	284	0.013
regulation of intracellular signal transduction	GO:1902531	236	0.013
oxoacid metabolic process	GO:0043436	103	0.012
cell motility	GO:0048870	251	0.012
nucleobase containing compound transport	GO:0015931	56	0.012
exocrine system development	GO:0035272	162	0.012
organic acid metabolic process	GO:0006082	103	0.012
positive regulation of viral process	GO:0048524	2	0.012
establishment of organelle localization	GO:0051656	122	0.012
hematopoietic or lymphoid organ development	GO:0048534	57	0.012
multi multicellular organism process	GO:0044706	123	0.012
regulation of mitotic cell cycle	GO:0007346	190	0.012
cell migration	GO:0016477	238	0.011
regulation of hydrolase activity	GO:0051336	97	0.011
cell division	GO:0051301	248	0.011
cytokinesis	GO:0000910	90	0.011
dna metabolic process	GO:0006259	227	0.011
rna transport	GO:0050658	46	0.011
cellular response to chemical stimulus	GO:0070887	199	0.011
response to hexose	GO:0009746	3	0.011
regulation of programmed cell death	GO:0043067	152	0.011
activation of cysteine type endopeptidase activity	GO:0097202	17	0.011
macromolecule catabolic process	GO:0009057	161	0.011
negative regulation of protein metabolic process	GO:0051248	85	0.011
negative regulation of cell death	GO:0060548	81	0.011
nucleocytoplasmic transport	GO:0006913	72	0.010
regulation of protein kinase activity	GO:0045859	51	0.010
protein modification by small protein conjugation or removal	GO:0070647	106	0.010
reproductive system development	GO:0061458	74	0.010
regulation of phosphorylation	GO:0042325	147	0.010
positive regulation of response to stimulus	GO:0048584	323	0.010
organonitrogen compound metabolic process	GO:1901564	318	0.010
negative regulation of cellular protein metabolic process	GO:0032269	85	0.010
positive regulation of cellular catabolic process	GO:0031331	95	0.010

RpL17 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.061
immune system disease	DOID:2914	0.036
anemia	DOID:2355	0.036
hematopoietic system disease	DOID:74	0.036
aplastic anemia	DOID:12449	0.026
bone marrow disease	DOID:4961	0.026
congenital hypoplastic anemia	DOID:1342	0.014
kidney disease	DOID:557	0.013
urinary system disease	DOID:18	0.013

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