IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Reg-2 (Dmel_CG3200)

Rhythmically expressed gene 2

(Aliases: Dmel\CG3200,Dreg-2,CG3200)

FLYBASE: FBgn0016715
Entrez: 38075
UniProtKB: Q94915

Process Predictions
Disease Predictions

Reg-2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
small molecule metabolic process	GO:0044281	305	0.187
single organism biosynthetic process	GO:0044711	206	0.091
response to external biotic stimulus	GO:0043207	293	0.084
neurotransmitter metabolic process	GO:0042133	2	0.074
ovarian follicle cell development	GO:0030707	248	0.073
organonitrogen compound metabolic process	GO:1901564	318	0.066
defense response to other organism	GO:0098542	225	0.055
oxoacid metabolic process	GO:0043436	103	0.053
organonitrogen compound biosynthetic process	GO:1901566	117	0.050
response to biotic stimulus	GO:0009607	294	0.049
response to abiotic stimulus	GO:0009628	341	0.047
response to organophosphorus	GO:0046683	2	0.047
defense response	GO:0006952	300	0.047
nucleotide metabolic process	GO:0009117	161	0.046
cellular catabolic process	GO:0044248	372	0.046
organic hydroxy compound metabolic process	GO:1901615	83	0.044
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.043
salivary gland development	GO:0007431	162	0.042
spermatogenesis	GO:0007283	200	0.041
lateral inhibition	GO:0046331	206	0.041
cellular ketone metabolic process	GO:0042180	24	0.040
epithelial cell development	GO:0002064	274	0.039
establishment of localization in cell	GO:0051649	402	0.037
neurotransmitter catabolic process	GO:0042135	1	0.036
organic substance catabolic process	GO:1901575	308	0.035
appendage development	GO:0048736	401	0.034
catabolic process	GO:0009056	409	0.034
positive regulation of hemocyte proliferation	GO:0035208	4	0.034
neuron projection guidance	GO:0097485	241	0.034
response to radiation	GO:0009314	155	0.033
connective tissue development	GO:0061448	3	0.033
epithelial cell migration	GO:0010631	148	0.033
single organism catabolic process	GO:0044712	228	0.032
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.031
homeostatic process	GO:0042592	199	0.031
carboxylic acid metabolic process	GO:0019752	92	0.031
taxis	GO:0042330	304	0.031
organophosphate metabolic process	GO:0019637	195	0.030
organic acid metabolic process	GO:0006082	103	0.030
protein localization	GO:0008104	284	0.030
nucleobase containing small molecule metabolic process	GO:0055086	174	0.029
multi multicellular organism process	GO:0044706	123	0.029
small molecule biosynthetic process	GO:0044283	37	0.028
purine nucleoside metabolic process	GO:0042278	127	0.028
cellular amine metabolic process	GO:0044106	12	0.027
nuclear division	GO:0000280	332	0.027
synaptic transmission	GO:0007268	288	0.027
response to organic substance	GO:0010033	284	0.027
response to monosaccharide	GO:0034284	4	0.026
detection of stimulus	GO:0051606	156	0.026
appendage morphogenesis	GO:0035107	397	0.026
male gamete generation	GO:0048232	201	0.026
neuron recognition	GO:0008038	101	0.026
respiratory system development	GO:0060541	213	0.025
cell migration	GO:0016477	238	0.025
multicellular organismal aging	GO:0010259	140	0.025
response to light stimulus	GO:0009416	124	0.024
fat soluble vitamin metabolic process	GO:0006775	1	0.024
organonitrogen compound catabolic process	GO:1901565	128	0.024
localization of cell	GO:0051674	257	0.024
chemotaxis	GO:0006935	249	0.023
cell motility	GO:0048870	251	0.023
columnar cuboidal epithelial cell development	GO:0002066	249	0.023
vitamin metabolic process	GO:0006766	2	0.023
negative regulation of gene expression	GO:0010629	387	0.023
chromosome segregation	GO:0007059	157	0.022
defense response to bacterium	GO:0042742	178	0.022
cell death	GO:0008219	279	0.022
open tracheal system development	GO:0007424	204	0.022
tissue migration	GO:0090130	155	0.022
exocrine system development	GO:0035272	162	0.022
purine containing compound metabolic process	GO:0072521	155	0.021
imaginal disc derived appendage development	GO:0048737	399	0.021
axonogenesis	GO:0007409	290	0.021
s adenosylmethionine cycle	GO:0033353	3	0.021
cell adhesion	GO:0007155	136	0.021
response to other organism	GO:0051707	293	0.021
wing disc morphogenesis	GO:0007472	344	0.021
axon development	GO:0061564	297	0.021
determination of adult lifespan	GO:0008340	137	0.021
biological adhesion	GO:0022610	138	0.020
ribonucleoside metabolic process	GO:0009119	127	0.020
small molecule catabolic process	GO:0044282	21	0.020
amine metabolic process	GO:0009308	12	0.020
programmed cell death	GO:0012501	257	0.020
nucleoside metabolic process	GO:0009116	127	0.019
epithelial cell differentiation	GO:0030855	322	0.019
response to oxygen containing compound	GO:1901700	200	0.019
regulation of multi organism process	GO:0043900	131	0.019
cellular macromolecule localization	GO:0070727	220	0.019
death	GO:0016265	284	0.019
alpha amino acid metabolic process	GO:1901605	20	0.018
cellular protein modification process	GO:0006464	438	0.018
salivary gland morphogenesis	GO:0007435	145	0.018
immune effector process	GO:0002252	98	0.018
nucleoside phosphate metabolic process	GO:0006753	162	0.018
camera type eye development	GO:0043010	4	0.018
negative regulation of cellular metabolic process	GO:0031324	382	0.017
peptide metabolic process	GO:0006518	80	0.017
response to glucose	GO:0009749	2	0.017
protein modification process	GO:0036211	438	0.017
negative regulation of response to stimulus	GO:0048585	258	0.017
regulation of immune system process	GO:0002682	176	0.017
response to hexose	GO:0009746	3	0.017
intracellular transport	GO:0046907	228	0.017
acetylcholine metabolic process	GO:0008291	2	0.017
post embryonic appendage morphogenesis	GO:0035120	385	0.017
aging	GO:0007568	143	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.016
ameboidal type cell migration	GO:0001667	151	0.016
regulation of cell death	GO:0010941	173	0.016
negative regulation of signaling	GO:0023057	219	0.016
regionalization	GO:0003002	416	0.016
response to bacterium	GO:0009617	198	0.016
ovarian follicle cell migration	GO:0007297	121	0.016
regulation of localization	GO:0032879	275	0.016
synaptic target recognition	GO:0008039	45	0.016
cell junction organization	GO:0034330	57	0.015
developmental growth	GO:0048589	280	0.015
cellular nitrogen compound catabolic process	GO:0044270	165	0.015
regulation of response to biotic stimulus	GO:0002831	63	0.015
autophagic cell death	GO:0048102	83	0.015
regulation of multicellular organismal development	GO:2000026	414	0.015
positive regulation of biosynthetic process	GO:0009891	316	0.015
developmental programmed cell death	GO:0010623	138	0.015
regulation of anatomical structure size	GO:0090066	163	0.015
regulation of cellular localization	GO:0060341	136	0.015
glycosyl compound metabolic process	GO:1901657	127	0.015
sulfur compound metabolic process	GO:0006790	59	0.015
regulation of tube architecture open tracheal system	GO:0035152	68	0.015
organelle fission	GO:0048285	340	0.015
immune system process	GO:0002376	347	0.014
negative regulation of cell communication	GO:0010648	223	0.014
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.014
oxidoreduction coenzyme metabolic process	GO:0006733	2	0.014
cell recognition	GO:0008037	102	0.014
negative regulation of signal transduction	GO:0009968	206	0.014
organic substance transport	GO:0071702	257	0.014
ketone biosynthetic process	GO:0042181	16	0.014
body morphogenesis	GO:0010171	2	0.014
eye development	GO:0001654	323	0.014
ethanolamine containing compound metabolic process	GO:0042439	4	0.014
meiotic nuclear division	GO:0007126	151	0.014
positive regulation of macromolecule metabolic process	GO:0010604	405	0.014
cell proliferation	GO:0008283	299	0.014
pyridine containing compound metabolic process	GO:0072524	3	0.013
axon guidance	GO:0007411	233	0.013
wound healing	GO:0042060	75	0.013
histolysis	GO:0007559	102	0.013
cellular protein localization	GO:0034613	160	0.013
positive regulation of gene expression	GO:0010628	290	0.013
reproductive behavior	GO:0019098	122	0.013
regulation of response to external stimulus	GO:0032101	115	0.013
maintenance of location	GO:0051235	73	0.013
response to wounding	GO:0009611	94	0.013
steroid metabolic process	GO:0008202	20	0.013
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
protein transport	GO:0015031	155	0.012
nicotinamide nucleotide metabolic process	GO:0046496	2	0.012
pyridine nucleotide metabolic process	GO:0019362	2	0.012
positive regulation of cell communication	GO:0010647	250	0.012
kidney development	GO:0001822	3	0.012
energy taxis	GO:0009453	21	0.012
salivary gland cell autophagic cell death	GO:0035071	83	0.012
positive regulation of response to stimulus	GO:0048584	323	0.012
gland development	GO:0048732	191	0.012
carbohydrate metabolic process	GO:0005975	82	0.012
defense response to gram negative bacterium	GO:0050829	94	0.012
positive regulation of cell migration	GO:0030335	2	0.012
compound eye development	GO:0048749	307	0.012
nucleobase containing compound catabolic process	GO:0034655	165	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
production of molecular mediator of immune response	GO:0002440	46	0.012
germarium derived egg chamber formation	GO:0007293	101	0.011
regulation of cellular ketone metabolic process	GO:0010565	3	0.011
growth	GO:0040007	359	0.011
meiotic cell cycle	GO:0051321	171	0.011
single organism intracellular transport	GO:1902582	207	0.011
border follicle cell migration	GO:0007298	113	0.011
intracellular signal transduction	GO:0035556	300	0.011
organic cyclic compound catabolic process	GO:1901361	168	0.011
neurological system process	GO:0050877	358	0.011
regulation of molecular function	GO:0065009	217	0.011
cellular modified amino acid metabolic process	GO:0006575	45	0.011
detection of external stimulus	GO:0009581	66	0.011
carbohydrate derivative metabolic process	GO:1901135	217	0.011
response to endogenous stimulus	GO:0009719	119	0.011
cellular amino acid metabolic process	GO:0006520	61	0.011
oxidation reduction process	GO:0055114	123	0.011
positive regulation of multi organism process	GO:0043902	40	0.011
phosphorylation	GO:0016310	294	0.011
ecdysteroid biosynthetic process	GO:0045456	15	0.011
response to purine containing compound	GO:0014074	12	0.011
positive regulation of immune system process	GO:0002684	68	0.011
multi organism reproductive behavior	GO:0044705	121	0.011
epithelium migration	GO:0090132	148	0.010
cellular homeostasis	GO:0019725	80	0.010
regulation of cell cycle	GO:0051726	291	0.010
endomembrane system organization	GO:0010256	119	0.010
single organism carbohydrate metabolic process	GO:0044723	72	0.010
regulation of immune effector process	GO:0002697	52	0.010
small gtpase mediated signal transduction	GO:0007264	88	0.010
centrosome organization	GO:0051297	163	0.010
chromosome organization	GO:0051276	360	0.010
response to temperature stimulus	GO:0009266	106	0.010
regulation of catalytic activity	GO:0050790	185	0.010
regulation of tube size	GO:0035150	46	0.010
regulation of cell size	GO:0008361	63	0.010
negative regulation of biosynthetic process	GO:0009890	277	0.010

Reg-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.016
	nervous system disease	DOID:863	0	0.011

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