Drosophila melanogaster

0 known processes

eIF5B (Dmel_CG10840)

CG10840 gene product from transcript CG10840-RB

(Aliases: anon-WO0118547.362,cIF2,IF2,CG14970,dIF2,A1,Dmel\CG10840,yIF2,CG10840)

eIF5B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment of localization in cellGO:00516494020.229
cellular protein modification processGO:00064644380.168
nuclear divisionGO:00002803320.138
positive regulation of biosynthetic processGO:00098913160.131
intracellular signal transductionGO:00355563000.105
protein modification by small protein conjugation or removalGO:00706471060.096
positive regulation of gene expressionGO:00106282900.094
positive regulation of nitrogen compound metabolic processGO:00511733540.088
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.083
chromatin modificationGO:00165681470.074
intracellular transportGO:00469072280.070
eye morphogenesisGO:00485922600.069
negative regulation of gene expressionGO:00106293870.064
compound eye morphogenesisGO:00017452490.063
positive regulation of cellular biosynthetic processGO:00313283160.062
protein modification processGO:00362114380.061
localization of cellGO:00516742570.061
positive regulation of nucleic acid templated transcriptionGO:19035082660.059
mitotic nuclear divisionGO:00070672130.058
positive regulation of macromolecule biosynthetic processGO:00105572830.057
eye developmentGO:00016543230.054
response to other organismGO:00517072930.054
positive regulation of response to stimulusGO:00485843230.053
regulation of multicellular organismal developmentGO:20000264140.050
transcription from rna polymerase ii promoterGO:00063663680.050
positive regulation of nucleobase containing compound metabolic processGO:00459353320.049
negative regulation of rna biosynthetic processGO:19026792400.049
negative regulation of nitrogen compound metabolic processGO:00511722650.048
chromosome organizationGO:00512763600.048
positive regulation of rna biosynthetic processGO:19026802660.047
organelle fissionGO:00482853400.047
spermatogenesisGO:00072832000.046
defense responseGO:00069523000.046
sensory organ morphogenesisGO:00905962600.046
organonitrogen compound metabolic processGO:19015643180.044
regulation of intracellular signal transductionGO:19025312360.043
catabolic processGO:00090564090.042
negative regulation of cellular metabolic processGO:00313243820.041
negative regulation of transcription dna templatedGO:00458922370.040
positive regulation of transcription dna templatedGO:00458932660.040
cytoplasmic transportGO:00164821300.039
negative regulation of rna metabolic processGO:00512532510.039
negative regulation of nucleic acid templated transcriptionGO:19035072400.039
cellular macromolecule catabolic processGO:00442651360.039
growthGO:00400073590.037
modification dependent macromolecule catabolic processGO:0043632790.037
compound eye developmentGO:00487493070.037
jak stat cascadeGO:0007259490.037
ubiquitin dependent protein catabolic processGO:0006511780.037
regulation of cellular component biogenesisGO:00440872010.036
positive regulation of cell communicationGO:00106472500.034
segmentationGO:00352822070.033
positive regulation of rna metabolic processGO:00512542710.033
regulation of cell cycleGO:00517262910.033
single organism intracellular transportGO:19025822070.033
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.032
negative regulation of nucleobase containing compound metabolic processGO:00459342610.032
protein localizationGO:00081042840.032
rrna processingGO:000636430.031
positive regulation of macromolecule metabolic processGO:00106044050.030
agingGO:00075681430.030
regulation of transcription from rna polymerase ii promoterGO:00063573780.030
single organism catabolic processGO:00447122280.030
body morphogenesisGO:001017120.030
purine ribonucleoside triphosphate catabolic processGO:00092071080.030
developmental growthGO:00485892800.029
male gamete generationGO:00482322010.029
regulation of catalytic activityGO:00507901850.029
small molecule metabolic processGO:00442813050.029
proteolysisGO:00065081920.028
organonitrogen compound biosynthetic processGO:19015661170.027
small gtpase mediated signal transductionGO:0007264880.027
dna repairGO:0006281540.027
organic substance catabolic processGO:19015753080.027
cell cycle phase transitionGO:00447701400.027
carbohydrate derivative catabolic processGO:19011361180.027
dna metabolic processGO:00062592270.026
mitotic spindle elongationGO:0000022810.026
carbohydrate derivative metabolic processGO:19011352170.026
negative regulation of cellular biosynthetic processGO:00313272770.026
regulation of cell differentiationGO:00455953020.026
organic substance transportGO:00717022570.025
cellular response to dna damage stimulusGO:00069742230.025
cellular catabolic processGO:00442483720.025
positive regulation of signalingGO:00230562430.025
vesicle mediated transportGO:00161923810.025
modification dependent protein catabolic processGO:0019941780.024
regulation of gene expression epigeneticGO:00400291280.024
histone modificationGO:00165701060.024
gene silencing by rnaGO:0031047570.024
developmental maturationGO:00217001720.023
gene silencingGO:00164581380.023
eye photoreceptor cell differentiationGO:00017541450.023
protein modification by small protein conjugationGO:0032446790.023
regulation of developmental growthGO:00486381740.023
columnar cuboidal epithelial cell developmentGO:00020662490.023
compound eye photoreceptor cell differentiationGO:00017511400.023
rna interferenceGO:0016246270.023
macromolecule catabolic processGO:00090571610.023
gland developmentGO:00487321910.023
wing disc morphogenesisGO:00074723440.022
purine nucleoside metabolic processGO:00422781270.022
regulation of catabolic processGO:00098941700.022
oocyte developmentGO:00485991240.022
appendage developmentGO:00487364010.022
ras protein signal transductionGO:0007265880.022
multicellular organismal agingGO:00102591400.022
innate immune responseGO:00450871440.022
defense response to bacteriumGO:00427421780.021
defense response to other organismGO:00985422250.021
nucleotide metabolic processGO:00091171610.021
protein ubiquitinationGO:0016567700.021
glycosyl compound catabolic processGO:19016581120.021
proteolysis involved in cellular protein catabolic processGO:0051603830.021
posttranscriptional gene silencingGO:0016441460.021
deathGO:00162652840.021
oocyte differentiationGO:00099941450.021
connective tissue developmentGO:006144830.020
regulation of oocyte developmentGO:0060281270.020
oocyte constructionGO:00073081120.020
positive regulation of signal transductionGO:00099672230.020
spindle elongationGO:0051231830.020
defense response to gram negative bacteriumGO:0050829940.020
regulation of response to stressGO:00801342000.019
axon developmentGO:00615642970.019
ribonucleoside triphosphate catabolic processGO:00092031080.019
stem cell maintenanceGO:0019827670.019
spindle organizationGO:00070512530.019
regulation of alternative mrna splicing via spliceosomeGO:0000381600.019
regulation of small gtpase mediated signal transductionGO:0051056930.019
chromatin organizationGO:00063252070.018
regulation of defense responseGO:00313471020.018
regulation of embryonic developmentGO:0045995680.018
organophosphate catabolic processGO:00464341120.018
epithelial cell differentiationGO:00308553220.018
cellular macromolecular complex assemblyGO:00346221530.018
regulation of mitotic cell cycle phase transitionGO:19019901300.018
translationGO:0006412690.018
positive regulation of proteolysisGO:0045862520.017
nucleoside phosphate metabolic processGO:00067531620.017
regulation of molecular functionGO:00650092170.017
ribonucleotide catabolic processGO:00092611090.017
central nervous system developmentGO:00074172010.017
post embryonic appendage morphogenesisGO:00351203850.017
posttranscriptional gene silencing by rnaGO:0035194450.017
single organism biosynthetic processGO:00447112060.017
embryonic pattern specificationGO:00098801740.017
cellularizationGO:0007349900.017
cell deathGO:00082192790.017
regulation of apoptotic processGO:00429811300.017
regulation of protein complex assemblyGO:0043254420.016
cell motilityGO:00488702510.016
regulation of hydrolase activityGO:0051336970.016
negative regulation of biosynthetic processGO:00098902770.016
head developmentGO:00603221350.016
photoreceptor cell developmentGO:0042461960.016
protein transportGO:00150311550.016
regulation of proteolysisGO:0030162870.016
regulation of multi organism processGO:00439001310.016
regulation of mitotic cell cycleGO:00073461900.016
phosphorylationGO:00163102940.016
covalent chromatin modificationGO:00165691060.016
posttranscriptional regulation of gene expressionGO:00106081450.015
retina development in camera type eyeGO:006004140.015
determination of adult lifespanGO:00083401370.015
positive regulation of cellular protein metabolic processGO:00322701180.015
ribonucleoside catabolic processGO:00424541120.015
regulation of protein metabolic processGO:00512462560.015
regulation of cellular protein metabolic processGO:00322682430.015
columnar cuboidal epithelial cell differentiationGO:00020652560.015
establishment or maintenance of cell polarityGO:00071631670.015
cellular amino acid metabolic processGO:0006520610.015
response to abiotic stimulusGO:00096283410.015
negative regulation of developmental processGO:00510932010.015
regulation of growthGO:00400082330.015
ribonucleoside triphosphate metabolic processGO:00091991190.015
positive regulation of peptidase activityGO:0010952290.015
germarium derived egg chamber formationGO:00072931010.015
regulation of cell cycle processGO:00105641810.014
nucleoside triphosphate metabolic processGO:00091411200.014
single organism cellular localizationGO:19025801800.014
synapse organizationGO:00508081960.014
programmed cell deathGO:00125012570.014
regulation of notch signaling pathwayGO:00085931000.014
oocyte anterior posterior axis specificationGO:0007314720.014
anterior posterior axis specificationGO:00099481090.014
phagocytosisGO:00069092150.014
heterocycle catabolic processGO:00467001660.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
skeletal muscle organ developmentGO:0060538480.014
regulation of ras protein signal transductionGO:0046578930.014
organic acid metabolic processGO:00060821030.014
maternal determination of anterior posterior axis embryoGO:0008358740.014
protein complex assemblyGO:00064612000.014
axis specificationGO:00097981670.014
negative regulation of response to stimulusGO:00485852580.014
protein modification by small protein removalGO:0070646280.014
regulation of mrna metabolic processGO:1903311720.014
cell cell signaling involved in cell fate commitmentGO:00451682100.014
extracellular structure organizationGO:0043062460.014
negative regulation of programmed cell deathGO:0043069720.013
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018480.013
protein complex biogenesisGO:00702712010.013
negative regulation of macromolecule biosynthetic processGO:00105582700.013
protein catabolic processGO:00301631010.013
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.013
purine nucleotide metabolic processGO:00061631460.013
cell maturationGO:00484691440.013
regulation of cell morphogenesisGO:00226041630.013
antimicrobial humoral responseGO:0019730990.013
gtp catabolic processGO:0006184720.013
rna splicingGO:0008380830.013
purine ribonucleoside catabolic processGO:00461301120.013
cellular protein catabolic processGO:0044257830.013
rubidium ion transportGO:003582610.013
nucleoside catabolic processGO:00091641120.013
reproductive structure developmentGO:0048608740.013
chromatin remodelingGO:0006338720.013
embryonic axis specificationGO:00005781070.012
stem cell developmentGO:0048864790.012
immune responseGO:00069552460.012
purine nucleoside catabolic processGO:00061521120.012
eye antennal disc morphogenesisGO:0007455340.012
ameboidal type cell migrationGO:00016671510.012
aromatic compound catabolic processGO:00194391660.012
ncrna processingGO:0034470300.012
purine ribonucleoside metabolic processGO:00461281270.012
nucleotide catabolic processGO:00091661090.012
cell migrationGO:00164772380.012
nuclear body organizationGO:003057560.012
regulation of anatomical structure sizeGO:00900661630.012
carboxylic acid metabolic processGO:0019752920.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.012
positive regulation of cellular catabolic processGO:0031331950.012
epithelial cell developmentGO:00020642740.012
humoral immune responseGO:00069591170.012
vesicle organizationGO:0016050440.012
o glycan processingGO:001626630.012
glycosyl compound metabolic processGO:19016571270.012
tripartite regional subdivisionGO:00073511030.012
pole plasm rna localizationGO:0007316520.012
purine containing compound metabolic processGO:00725211550.012
response to biotic stimulusGO:00096072940.012
monocarboxylic acid transportGO:001571830.011
nucleobase containing small molecule metabolic processGO:00550861740.011
positive regulation of growthGO:0045927750.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
chromosome segregationGO:00070591570.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.011
pole plasm mrna localizationGO:0019094490.011
ncrna metabolic processGO:0034660430.011
nucleus organizationGO:0006997450.011
membrane organizationGO:00610241120.011
anterior posterior pattern specificationGO:00099521360.011
intracellular mrna localization involved in pattern specification processGO:0060810560.011
ribose phosphate metabolic processGO:00196931450.011
protein maturationGO:0051604710.011
positive regulation of intracellular signal transductionGO:19025331160.011
cytoplasmic translationGO:000218100.011
intracellular mrna localizationGO:0008298660.011
signal transduction by phosphorylationGO:00230141070.011
positive regulation of nucleoside metabolic processGO:0045979470.011
gtp metabolic processGO:0046039720.011
neurological system processGO:00508773580.011
negative regulation of signal transductionGO:00099682060.011
positive regulation of protein catabolic processGO:0045732340.011
tissue morphogenesisGO:00487292970.011
establishment or maintenance of cytoskeleton polarityGO:0030952440.011
response to ecdysoneGO:0035075340.011
negative regulation of cell communicationGO:00106482230.011
imaginal disc derived leg morphogenesisGO:0007480800.011
regulation of cysteine type endopeptidase activityGO:2000116270.011
purine containing compound catabolic processGO:00725231120.010
regulation of cell cycle phase transitionGO:19019871300.010
regulation of cellular component sizeGO:0032535980.010
spindle assemblyGO:0051225800.010
nucleoside metabolic processGO:00091161270.010
purine nucleotide catabolic processGO:00061951090.010
tissue deathGO:00162711020.010
ovarian follicle cell migrationGO:00072971210.010
histolysisGO:00075591020.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.010
nucleoside triphosphate catabolic processGO:00091431080.010
nuclear exportGO:0051168240.010
regulation of nervous system developmentGO:00519602480.010
single organism membrane buddingGO:190259120.010
regulation of gtp catabolic processGO:0033124440.010
positive regulation of catalytic activityGO:00430851180.010
myotube cell developmentGO:001490430.010
cellular nitrogen compound catabolic processGO:00442701650.010

eIF5B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.091
nervous system diseaseDOID:86300.039
neurodegenerative diseaseDOID:128900.034
central nervous system diseaseDOID:33100.034
urinary system diseaseDOID:1800.014
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
sensory system diseaseDOID:005015500.012
disease of metabolismDOID:001466700.011