Drosophila melanogaster

21 known processes

Hey (Dmel_CG11194)

Hairy/E(spl)-related with YRPW motif

(Aliases: dHey,bHLHe44,CG11194,hesr-1,hey,d-hey,Hesr-1,Dmel\CG11194)

Hey biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.433
Human Mouse
positive regulation of macromolecule biosynthetic processGO:00105572830.277
Human Mouse
transcription from rna polymerase ii promoterGO:00063663680.273
Human Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.270
Human Mouse
regulation of transcription from rna polymerase ii promoterGO:00063573780.256
Human Mouse
positive regulation of macromolecule metabolic processGO:00106044050.251
Human Mouse
positive regulation of cellular biosynthetic processGO:00313283160.243
Human Mouse
negative regulation of rna metabolic processGO:00512532510.215
Human Zebrafish Mouse
chromosome organizationGO:00512763600.197
negative regulation of nitrogen compound metabolic processGO:00511722650.192
Human Zebrafish Mouse
positive regulation of transcription dna templatedGO:00458932660.181
Human Mouse
negative regulation of cellular biosynthetic processGO:00313272770.173
Human Zebrafish Mouse
positive regulation of rna biosynthetic processGO:19026802660.171
Human Mouse
regulation of multicellular organismal developmentGO:20000264140.154
Mouse
negative regulation of transcription dna templatedGO:00458922370.151
Human Zebrafish Mouse
negative regulation of nucleobase containing compound metabolic processGO:00459342610.137
Human Zebrafish Mouse
positive regulation of nucleic acid templated transcriptionGO:19035082660.129
Human Mouse
positive regulation of gene expressionGO:00106282900.128
Human Mouse
cell divisionGO:00513012480.128
multi organism reproductive behaviorGO:00447051210.124
positive regulation of rna metabolic processGO:00512542710.124
Human Mouse
cellular protein modification processGO:00064644380.121
embryonic pattern specificationGO:00098801740.115
blastoderm segmentationGO:00073501590.113
vesicle mediated transportGO:00161923810.111
taxisGO:00423303040.106
reproductive behaviorGO:00190981220.101
organic hydroxy compound metabolic processGO:1901615830.101
cell migrationGO:00164772380.098
central nervous system developmentGO:00074172010.098
protein modification processGO:00362114380.095
covalent chromatin modificationGO:00165691060.092
columnar cuboidal epithelial cell differentiationGO:00020652560.091
epithelial cell developmentGO:00020642740.091
negative regulation of macromolecule biosynthetic processGO:00105582700.090
Human Zebrafish Mouse
positive regulation of biosynthetic processGO:00098913160.090
Human Mouse
neuron fate commitmentGO:0048663500.085
regionalizationGO:00030024160.084
Mouse
eye photoreceptor cell differentiationGO:00017541450.081
cell proliferationGO:00082832990.076
Mouse
compound eye morphogenesisGO:00017452490.075
epithelial cell differentiationGO:00308553220.074
Zebrafish Mouse
neuron projection guidanceGO:00974852410.073
regulation of cell proliferationGO:00421271630.073
Mouse
axonogenesisGO:00074092900.073
localization of cellGO:00516742570.072
brain developmentGO:00074201200.072
negative regulation of gene expressionGO:00106293870.071
Human Zebrafish Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.070
Human Mouse
immune responseGO:00069552460.070
organonitrogen compound metabolic processGO:19015643180.069
axon developmentGO:00615642970.068
cellular response to abiotic stimulusGO:0071214580.067
single organism behaviorGO:00447083910.067
positive regulation of nitrogen compound metabolic processGO:00511733540.065
Human Mouse
organonitrogen compound biosynthetic processGO:19015661170.064
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.064
Human Zebrafish Mouse
cell fate determinationGO:0001709910.063
negative regulation of biosynthetic processGO:00098902770.062
Human Zebrafish Mouse
response to abiotic stimulusGO:00096283410.062
response to radiationGO:00093141550.062
regulation of cellular component biogenesisGO:00440872010.061
Human
cellular response to radiationGO:0071478520.061
adult behaviorGO:00305341370.060
neural precursor cell proliferationGO:0061351750.059
negative regulation of cellular metabolic processGO:00313243820.059
Human Zebrafish Mouse
histone modificationGO:00165701060.058
chromatin modificationGO:00165681470.057
cell motilityGO:00488702510.056
detection of stimulusGO:00516061560.056
multi organism behaviorGO:00517051750.055
eye morphogenesisGO:00485922600.055
regulation of synapse structure and activityGO:00508031280.054
regulation of protein metabolic processGO:00512462560.054
multicellular organismal reproductive behaviorGO:00330571100.054
response to biotic stimulusGO:00096072940.053
photoreceptor cell differentiationGO:00465301700.052
stem cell developmentGO:0048864790.052
Mouse
cell cell signaling involved in cell fate commitmentGO:00451682100.052
salivary gland developmentGO:00074311620.052
regulation of anatomical structure morphogenesisGO:00226032420.052
Mouse
small molecule metabolic processGO:00442813050.051
compound eye photoreceptor cell differentiationGO:00017511400.051
regulation of cell morphogenesisGO:00226041630.050
mesenchymal cell differentiationGO:004876210.050
Mouse
axon guidanceGO:00074112330.049
body morphogenesisGO:001017120.048
stem cell divisionGO:0017145690.047
stem cell proliferationGO:0072089880.046
cell adhesionGO:00071551360.046
dendrite morphogenesisGO:00488131990.045
g protein coupled receptor signaling pathwayGO:00071861360.045
catabolic processGO:00090564090.045
oxoacid metabolic processGO:00434361030.045
regulation of nervous system developmentGO:00519602480.045
Mouse
macromolecular complex assemblyGO:00650032560.045
Human Mouse
response to organic substanceGO:00100332840.045
Human Mouse
chemotaxisGO:00069352490.045
programmed cell deathGO:00125012570.044
Mouse
hematopoietic or lymphoid organ developmentGO:0048534570.043
synaptic transmissionGO:00072682880.043
response to oxygen containing compoundGO:19017002000.043
dendrite developmentGO:00163582040.042
cell junction assemblyGO:0034329420.042
compound eye developmentGO:00487493070.040
response to light stimulusGO:00094161240.040
synapse organizationGO:00508081960.040
single organism intracellular transportGO:19025822070.040
regulation of cell differentiationGO:00455953020.039
Mouse
cellular catabolic processGO:00442483720.039
columnar cuboidal epithelial cell developmentGO:00020662490.039
protein alkylationGO:0008213430.039
cell junction organizationGO:0034330570.039
gland developmentGO:00487321910.039
gland morphogenesisGO:00226121450.038
neuroblast divisionGO:0055057350.037
intracellular signal transductionGO:00355563000.037
regulation of cellular protein metabolic processGO:00322682430.037
negative regulation of cell differentiationGO:00455961430.037
Mouse
mesenchymal cell developmentGO:001403110.037
Mouse
circulatory system developmentGO:0072359820.037
Human Zebrafish Mouse
spinal cord developmentGO:002151010.036
positive regulation of multi organism processGO:0043902400.036
head developmentGO:00603221350.036
neuroblast proliferationGO:0007405740.036
carboxylic acid metabolic processGO:0019752920.036
cellular amino acid metabolic processGO:0006520610.036
regulation of oocyte developmentGO:0060281270.035
response to external biotic stimulusGO:00432072930.035
endocytosisGO:00068973100.034
chromatin remodelingGO:0006338720.034
regulation of multi organism processGO:00439001310.034
organic substance catabolic processGO:19015753080.033
positive regulation of response to stimulusGO:00485843230.033
adult locomotory behaviorGO:0008344760.033
embryo development ending in birth or egg hatchingGO:00097921520.033
Mouse
connective tissue developmentGO:006144830.032
macromolecule methylationGO:0043414450.032
organic acid metabolic processGO:00060821030.032
leg disc developmentGO:0035218920.031
germ cell migrationGO:0008354430.031
multi multicellular organism processGO:00447061230.030
immune response regulating signaling pathwayGO:000276420.030
developmental maturationGO:00217001720.030
neuron recognitionGO:00080381010.029
segmentationGO:00352822070.029
protein complex assemblyGO:00064612000.029
Human
organic hydroxy compound biosynthetic processGO:1901617210.029
negative regulation of nucleic acid templated transcriptionGO:19035072400.029
Human Zebrafish Mouse
positive regulation of cell proliferationGO:0008284470.028
Mouse
cellular response to dna damage stimulusGO:00069742230.028
eye photoreceptor cell fate commitmentGO:0042706370.028
regulation of programmed cell deathGO:00430671520.028
Mouse
regulation of syncytium formation by plasma membrane fusionGO:006014260.028
molting cycle chitin based cuticleGO:0007591560.028
regulation of chromosome organizationGO:0033044640.027
vitamin metabolic processGO:000676620.027
regulation of organ morphogenesisGO:2000027780.027
response to lipopolysaccharideGO:003249640.027
morphogenesis of an epitheliumGO:00020092760.027
Mouse
defense responseGO:00069523000.027
compound eye photoreceptor fate commitmentGO:0001752360.027
regulation of phosphate metabolic processGO:00192202100.027
protein complex biogenesisGO:00702712010.026
Human
camera type eye developmentGO:004301040.026
outflow tract morphogenesisGO:000315140.026
Mouse
eye developmentGO:00016543230.026
periodic partitioningGO:0007365290.026
biological adhesionGO:00226101380.026
chromatin organizationGO:00063252070.025
methylationGO:0032259470.025
regulation of notch signaling pathwayGO:00085931000.025
Human Mouse
negative regulation of cell communicationGO:00106482230.025
Human Mouse
tube developmentGO:00352952440.025
Mouse
somatic stem cell divisionGO:0048103370.025
regulation of molecular functionGO:00650092170.025
Human Mouse
exocrine system developmentGO:00352721620.025
phosphorylationGO:00163102940.024
cellular response to organic substanceGO:00713101320.024
Human Mouse
organelle fissionGO:00482853400.024
notch signaling pathwayGO:00072191200.024
Human Zebrafish Mouse
regulation of response to external stimulusGO:00321011150.024
forebrain developmentGO:003090020.024
limb developmentGO:006017310.024
regulation of behaviorGO:0050795750.024
regulation of neural precursor cell proliferationGO:2000177350.023
regulation of cell cycleGO:00517262910.023
response to other organismGO:00517072930.023
imaginal disc derived appendage developmentGO:00487373990.023
stem cell differentiationGO:00488631170.023
Mouse
regulation of apoptotic processGO:00429811300.023
Mouse
establishment or maintenance of cell polarityGO:00071631670.023
larval developmentGO:00021641040.023
negative regulation of cell cycle phase transitionGO:19019881030.023
telencephalon developmentGO:002153720.022
locomotory behaviorGO:00076261760.022
imaginal disc derived leg morphogenesisGO:0007480800.022
regulation of antimicrobial peptide productionGO:0002784440.022
segment polarity determinationGO:0007367250.022
response to endogenous stimulusGO:00097191190.022
Human Mouse
cell deathGO:00082192790.022
Mouse
cellular macromolecular complex assemblyGO:00346221530.021
Mouse
neurological system processGO:00508773580.021
regulation of immune system processGO:00026821760.021
ovarian follicle cell developmentGO:00307072480.021
regulation of protein modification processGO:00313991120.021
establishment of planar polarityGO:0001736870.021
regulation of embryonic developmentGO:0045995680.021
antimicrobial humoral responseGO:0019730990.021
protein catabolic processGO:00301631010.021
cellular response to chemical stimulusGO:00708871990.021
Human Mouse
regulation of humoral immune responseGO:0002920510.021
regulation of organelle organizationGO:00330431960.021
deathGO:00162652840.021
Mouse
tissue morphogenesisGO:00487292970.021
Mouse
asymmetric stem cell divisionGO:0098722490.020
imaginal disc derived wing morphogenesisGO:00074763370.020
amine metabolic processGO:0009308120.020
lateral inhibitionGO:00463312060.020
defense response to other organismGO:00985422250.020
developmental programmed cell deathGO:00106231380.020
response to organic cyclic compoundGO:0014070890.020
Human
cell maturationGO:00484691440.020
single organism cellular localizationGO:19025801800.020
ovipositionGO:0018991190.020
development of primary sexual characteristicsGO:0045137500.020
synapse assemblyGO:00074161430.020
regulation of phosphorus metabolic processGO:00511742100.020
sensory perception of chemical stimulusGO:00076061160.020
negative regulation of multicellular organismal processGO:00512411420.020
Mouse
limb morphogenesisGO:003510810.020
spindle organizationGO:00070512530.019
sensory organ morphogenesisGO:00905962600.019
nucleoside phosphate metabolic processGO:00067531620.019
mitotic spindle organizationGO:00070522200.019
regulation of cellular ketone metabolic processGO:001056530.019
regulation of neurogenesisGO:00507671580.019
Mouse
nuclear transportGO:0051169720.019
immune response activating signal transductionGO:000275720.019
multicellular organismal agingGO:00102591400.019
cell cell junction organizationGO:0045216550.019
photoreceptor cell fate commitmentGO:0046552410.019
response to nitrogen compoundGO:1901698900.019
single organism catabolic processGO:00447122280.019
regulation of localizationGO:00328792750.019
regulation of cell deathGO:00109411730.019
Mouse
establishment of tissue polarityGO:0007164870.019
catechol containing compound biosynthetic processGO:000971330.018
organelle localizationGO:00516401480.018
regulation of chromatin organizationGO:1902275320.018
positive regulation of developmental processGO:00510941430.018
Mouse
immune system processGO:00023763470.018
macromolecule catabolic processGO:00090571610.018
response to organophosphorusGO:004668320.018
gliogenesisGO:0042063800.018
positive regulation of antimicrobial humoral responseGO:0002760280.018
cellular response to biotic stimulusGO:007121640.018
regulation of ras protein signal transductionGO:0046578930.018
salivary gland morphogenesisGO:00074351450.018
ras protein signal transductionGO:0007265880.017
actin cytoskeleton organizationGO:00300362060.017
developmental growthGO:00485892800.017
Mouse
actin filament based processGO:00300292200.017
response to inorganic substanceGO:0010035440.017
organic cyclic compound catabolic processGO:19013611680.017
neuronal stem cell divisionGO:0036445350.017
single organism biosynthetic processGO:00447112060.017
positive regulation of immune responseGO:0050778630.017
rna processingGO:00063961470.017
ethanolamine containing compound metabolic processGO:004243940.017
nuclear divisionGO:00002803320.017
positive regulation of cellular protein metabolic processGO:00322701180.017
cellular ketone metabolic processGO:0042180240.017
mitotic cell cycle embryonicGO:0045448380.017
regulation of synapse organizationGO:00508071100.017
regulation of cellular amine metabolic processGO:003323830.017
response to alcoholGO:0097305950.017
positive regulation of cell migrationGO:003033520.016
response to woundingGO:0009611940.016
regulation of cellular amide metabolic processGO:0034248390.016
wound healingGO:0042060750.016
cytoplasmic transportGO:00164821300.016
humoral immune responseGO:00069591170.016
regulation of mitotic cell cycleGO:00073461900.016
digestive tract developmentGO:00485651490.016
positive regulation of cellular component organizationGO:00511301560.016
histone methylationGO:0016571400.016
small gtpase mediated signal transductionGO:0007264880.016
negative regulation of notch signaling pathwayGO:0045746410.016
Human Mouse
dorsal ventral pattern formationGO:00099531330.016
regulation of synaptic transmissionGO:0050804690.016
negative regulation of cell cycleGO:00457861160.016
growthGO:00400073590.016
Mouse
secondary metabolic processGO:0019748750.016
hemopoiesisGO:0030097460.016
digestive system developmentGO:00551231490.016
regulation of response to stressGO:00801342000.016
chromosome segregationGO:00070591570.015
striated muscle tissue developmentGO:0014706270.015
Mouse
cellular biogenic amine catabolic processGO:004240210.015
regulation of immune effector processGO:0002697520.015
neuromuscular junction developmentGO:00075281490.015
male mating behaviorGO:0060179700.015
skeletal muscle organ developmentGO:0060538480.015
Mouse
fertilizationGO:0009566260.015
amide biosynthetic processGO:0043604420.015
negative regulation of cell deathGO:0060548810.015
Mouse
muscle tissue morphogenesisGO:006041520.015
Mouse
cognitionGO:00508901410.015
cellular response to molecule of bacterial originGO:007121930.015
protein maturationGO:0051604710.015
establishment of glial blood brain barrierGO:0060857140.014
gastrulation with mouth forming firstGO:0001703360.014
microtubule organizing center organizationGO:00310231680.014
organelle assemblyGO:00709251980.014
regulation of cellular amino acid metabolic processGO:000652100.014
secretionGO:00469031090.014
phenol containing compound metabolic processGO:0018958570.014
regulation of reproductive processGO:2000241540.014
positive regulation of phosphorus metabolic processGO:00105621390.014
embryonic development via the syncytial blastodermGO:00017001480.014
regulation of antimicrobial peptide biosynthetic processGO:0002805380.014
epidermis developmentGO:0008544650.014
Mouse
cellular response to endogenous stimulusGO:0071495800.014
Human Mouse
mitotic nuclear divisionGO:00070672130.014
asymmetric cell divisionGO:0008356370.014
positive regulation of organelle organizationGO:0010638650.014
protein acetylationGO:0006473390.014
embryonic morphogenesisGO:00485982060.014
posttranscriptional regulation of gene expressionGO:00106081450.014
regulation of production of molecular mediator of immune responseGO:0002700440.014
protein dna complex subunit organizationGO:0071824860.014
Mouse
muscle structure developmentGO:00610612240.014
Human Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.014
rna localizationGO:00064031150.013
monocarboxylic acid transportGO:001571830.013
glial cell differentiationGO:0010001350.013
steroid catabolic processGO:000670610.013
negative regulation of protein metabolic processGO:0051248850.013
gastrulation involving germ band extensionGO:0010004360.013
cellular amine metabolic processGO:0044106120.013
cellular amide metabolic processGO:0043603800.013
carbohydrate derivative metabolic processGO:19011352170.013
establishment of organelle localizationGO:00516561220.013
melanin metabolic processGO:0006582470.013
detection of stimulus involved in sensory perceptionGO:0050906920.013
meiosis iGO:0007127590.013
negative regulation of mitotic cell cycleGO:00459301090.013
memoryGO:0007613940.013
mushroom body developmentGO:0016319700.013
morphogenesis of embryonic epitheliumGO:0016331940.013
regulation of mitotic cell cycle phase transitionGO:19019901300.013
single fertilizationGO:0007338240.013
embryonic organ developmentGO:0048568500.013
Mouse
cell recognitionGO:00080371020.013
intracellular transportGO:00469072280.013
detection of light stimulusGO:0009583580.013
positive regulation of cell motilityGO:200014730.013
negative regulation of developmental processGO:00510932010.013
Mouse
imaginal disc derived appendage morphogenesisGO:00351143950.013
positive regulation of cellular amine metabolic processGO:003324000.013
chitin based cuticle developmentGO:0040003490.013
ribose phosphate metabolic processGO:00196931450.013
phototransductionGO:0007602520.013
negative regulation of signal transductionGO:00099682060.012
Human Mouse
response to oxidative stressGO:0006979860.012
apoptotic processGO:00069151590.012
Mouse
regulation of immune responseGO:00507761180.012
detection of abiotic stimulusGO:0009582660.012
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.012
kidney morphogenesisGO:006099330.012
Mouse
wing disc morphogenesisGO:00074723440.012
serotonin receptor signaling pathwayGO:000721050.012
regulation of locomotionGO:0040012420.012
innate immune responseGO:00450871440.012
dna metabolic processGO:00062592270.012
respiratory system developmentGO:00605412130.012
negative regulation of signalingGO:00230572190.012
Human Mouse
lipid metabolic processGO:00066291210.012
ameboidal type cell migrationGO:00016671510.012
aromatic compound catabolic processGO:00194391660.012
peripheral nervous system developmentGO:0007422520.012
antimicrobial peptide productionGO:0002775460.012
extrinsic apoptotic signaling pathwayGO:009719110.012
protein methylationGO:0006479430.012
cell cycle checkpointGO:0000075950.012
positive regulation of protein metabolic processGO:00512471280.012
mrna metabolic processGO:00160711240.012
syncytium formation by plasma membrane fusionGO:0000768430.012
neuroblast differentiationGO:0014016290.012
pigmentationGO:0043473750.012
regulation of anatomical structure sizeGO:00900661630.012
regulation of cell developmentGO:00602842150.012
Mouse
single organism carbohydrate metabolic processGO:0044723720.012
response to hypoxiaGO:0001666530.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.012
response to extracellular stimulusGO:00099911160.012
mitotic g2 m transition checkpointGO:0044818700.012
agingGO:00075681430.011
negative regulation of cell proliferationGO:0008285690.011
regulation of gene expression epigeneticGO:00400291280.011
detection of chemical stimulusGO:0009593930.011
dna damage checkpointGO:0000077780.011
dorsal ventral axis specificationGO:0009950660.011
photoreceptor cell developmentGO:0042461960.011
protein heterooligomerizationGO:005129140.011
border follicle cell migrationGO:00072981130.011
positive regulation of hydrolase activityGO:0051345780.011
establishment of localization in cellGO:00516494020.011
morphogenesis of a polarized epitheliumGO:0001738930.011
cellular response to light intensityGO:007148410.011
positive regulation of apoptotic processGO:0043065470.011
protein localization to nucleusGO:0034504550.011
chemosensory behaviorGO:00076351060.011
regulation of response to biotic stimulusGO:0002831630.011
ovulationGO:003072840.011
organic substance transportGO:00717022570.011
hematopoietic progenitor cell differentiationGO:000224410.011
cellular response to lipopolysaccharideGO:007122230.011
negative regulation of gene expression epigeneticGO:0045814770.011
dendrite guidanceGO:0070983210.011
regulation of growthGO:00400082330.011
Mouse
negative regulation of programmed cell deathGO:0043069720.011
Mouse
detection of external stimulusGO:0009581660.011
epithelium migrationGO:00901321480.011
secretion by cellGO:00329401010.011
regulation of antimicrobial humoral responseGO:0002759500.011
regulation of cell maturationGO:1903429270.011
cellular component assembly involved in morphogenesisGO:00109271510.011
nephron tubule developmentGO:007208030.011
Mouse
regulation of developmental growthGO:00486381740.011
Mouse
negative regulation of rna biosynthetic processGO:19026792400.011
Human Zebrafish Mouse
positive regulation of cell cycleGO:0045787430.010
positive regulation of cell deathGO:0010942690.010
nucleobase containing small molecule metabolic processGO:00550861740.010
nucleotide metabolic processGO:00091171610.010
anatomical structure homeostasisGO:0060249970.010
response to high light intensityGO:000964410.010
embryonic axis specificationGO:00005781070.010
regulation of cellular catabolic processGO:00313291570.010
renal tubule developmentGO:0061326640.010
Mouse
nitrogen compound transportGO:0071705850.010
anterior posterior axis specificationGO:00099481090.010
Mouse
regulation of glial cell differentiationGO:004568510.010
leg disc morphogenesisGO:0007478800.010
cardiac cell fate commitmentGO:0060911170.010
myoblast proliferationGO:005145030.010
regulation of catalytic activityGO:00507901850.010
larval behaviorGO:0030537420.010
cell cell junction assemblyGO:0007043380.010
antimicrobial peptide biosynthetic processGO:0002777380.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.010
cellular response to hormone stimulusGO:0032870440.010
Human
regulation of transportGO:00510491810.010

Hey disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.033
disease of cellular proliferationDOID:1456600.033
cancerDOID:16200.033
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.012
sensory system diseaseDOID:005015500.012
waardenburg s syndromeDOID:925800.011