Drosophila melanogaster

65 known processes

cpx (Dmel_CG32490)

complexin

(Aliases: CG32490,BcDNA:HL04936,BcDNA:RH31085,dmCplx,Cpx,Dmel\CG32490,BcDNA:GH27718,BcDNA:RH26459)

cpx biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic transmissionGO:00072682880.998
neuromuscular junction developmentGO:00075281490.953
regulation of synapse organizationGO:00508071100.932
synaptic growth at neuromuscular junctionGO:00511241190.901
regulation of synaptic growth at neuromuscular junctionGO:0008582890.890
synaptic vesicle recyclingGO:0036465280.871
synapse assemblyGO:00074161430.837
synapse organizationGO:00508081960.827
synaptic vesicle transportGO:0048489500.790
synaptic vesicle endocytosisGO:0048488280.692
sensory perception of mechanical stimulusGO:0050954720.686
regulation of synapse structure and activityGO:00508031280.677
regulation of vesicle mediated transportGO:0060627590.581
establishment of localization in cellGO:00516494020.571
establishment of vesicle localizationGO:0051650510.552
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.534
regulation of synapse assemblyGO:0051963940.460
neuromuscular synaptic transmissionGO:0007274670.440
morphogenesis of an epitheliumGO:00020092760.435
regulation of nervous system developmentGO:00519602480.371
response to abiotic stimulusGO:00096283410.313
vesicle mediated transportGO:00161923810.295
regulation of cellular component biogenesisGO:00440872010.294
establishment of organelle localizationGO:00516561220.291
signal releaseGO:0023061490.290
negative regulation of multicellular organismal processGO:00512411420.288
response to temperature stimulusGO:00092661060.287
synaptic vesicle localizationGO:0097479530.284
organelle localizationGO:00516401480.282
positive regulation of transportGO:0051050920.247
regulation of synaptic plasticityGO:0048167140.219
Mouse
organonitrogen compound catabolic processGO:19015651280.219
establishment of synaptic vesicle localizationGO:0097480500.213
regulation of secretion by cellGO:1903530390.208
regulation of neurotransmitter secretionGO:0046928140.200
regulation of multicellular organismal developmentGO:20000264140.198
regulation of cellular localizationGO:00603411360.194
regulation of synaptic transmissionGO:0050804690.188
single organism cellular localizationGO:19025801800.187
sensory perceptionGO:00076001960.172
posttranscriptional regulation of gene expressionGO:00106081450.165
negative regulation of synapse assemblyGO:0051964390.162
response to radiationGO:00093141550.160
developmental growthGO:00485892800.159
taxisGO:00423303040.151
sensory perception of soundGO:0007605560.151
single organism membrane fusionGO:0044801420.148
regulation of transportGO:00510491810.145
growthGO:00400073590.140
negative regulation of developmental processGO:00510932010.136
regulation of cell deathGO:00109411730.135
locomotory behaviorGO:00076261760.134
nucleoside catabolic processGO:00091641120.128
endocytosisGO:00068973100.122
programmed cell deathGO:00125012570.119
photoreceptor cell developmentGO:0042461960.115
deathGO:00162652840.115
regulation of establishment of protein localizationGO:0070201610.114
response to light stimulusGO:00094161240.114
chemotaxisGO:00069352490.112
actin filament based processGO:00300292200.110
sensory organ morphogenesisGO:00905962600.107
synaptic vesicle fusion to presynaptic membraneGO:003162970.102
flight behaviorGO:0007629260.102
single organism membrane organizationGO:0044802930.101
eye photoreceptor cell differentiationGO:00017541450.100
vesicle organizationGO:0016050440.098
axonogenesisGO:00074092900.091
regulation of endocytosisGO:0030100370.089
muscle organ developmentGO:00075171270.087
regulation of localizationGO:00328792750.086
compound eye photoreceptor developmentGO:0042051780.086
eye photoreceptor cell developmentGO:0042462810.083
lipid modificationGO:0030258240.082
secretion by cellGO:00329401010.081
vesicle localizationGO:0051648550.080
positive regulation of nucleotide catabolic processGO:0030813460.080
single organism catabolic processGO:00447122280.080
regulation of catabolic processGO:00098941700.078
carbohydrate derivative catabolic processGO:19011361180.077
catabolic processGO:00090564090.077
purine ribonucleoside triphosphate catabolic processGO:00092071080.074
oocyte differentiationGO:00099941450.070
regulation of purine nucleotide metabolic processGO:1900542620.070
eye developmentGO:00016543230.070
regulation of neurotransmitter levelsGO:0001505380.068
ribonucleoside triphosphate metabolic processGO:00091991190.067
compound eye developmentGO:00487493070.067
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.066
segmentationGO:00352822070.065
organelle fusionGO:0048284460.065
cell deathGO:00082192790.064
positive regulation of apoptotic signaling pathwayGO:200123540.061
multi multicellular organism processGO:00447061230.060
reproductive behaviorGO:00190981220.059
cellular lipid metabolic processGO:0044255830.059
positive regulation of signalingGO:00230562430.058
neurotransmitter transportGO:0006836370.058
membrane organizationGO:00610241120.057
oocyte constructionGO:00073081120.057
regulation of cell differentiationGO:00455953020.057
purine nucleoside triphosphate metabolic processGO:00091441190.056
larval developmentGO:00021641040.056
cortical cytoskeleton organizationGO:0030865290.056
protein localizationGO:00081042840.056
nucleoside triphosphate metabolic processGO:00091411200.055
intracellular signal transductionGO:00355563000.055
eye morphogenesisGO:00485922600.054
cellular response to chemical stimulusGO:00708871990.054
purine nucleotide metabolic processGO:00061631460.054
negative regulation of cell differentiationGO:00455961430.053
regionalizationGO:00030024160.053
neurological system processGO:00508773580.053
neuroblast proliferationGO:0007405740.052
mating behaviorGO:00076171060.052
regulation of purine nucleotide catabolic processGO:0033121480.052
regulation of cell projection organizationGO:0031344920.051
maintenance of presynaptic active zone structureGO:004879080.051
regulation of growthGO:00400082330.051
regulation of cytoskeleton organizationGO:0051493890.051
developmental programmed cell deathGO:00106231380.050
establishment of cell polarityGO:0030010400.050
cell maturationGO:00484691440.050
oocyte developmentGO:00485991240.049
purine ribonucleoside triphosphate metabolic processGO:00092051190.049
filopodium assemblyGO:0046847330.049
organophosphate catabolic processGO:00464341120.048
regulation of cellular catabolic processGO:00313291570.048
purine ribonucleoside catabolic processGO:00461301120.048
positive regulation of synaptic vesicle endocytosisGO:190024440.048
nuclear divisionGO:00002803320.048
negative regulation of signalingGO:00230572190.047
negative regulation of cellular component organizationGO:00511291080.046
embryonic pattern specificationGO:00098801740.046
negative regulation of nervous system developmentGO:0051961920.046
stem cell differentiationGO:00488631170.046
cellular nitrogen compound catabolic processGO:00442701650.046
organic substance transportGO:00717022570.046
Mouse
positive regulation of nucleotide metabolic processGO:0045981550.046
positive regulation of synaptic vesicle recyclingGO:190342340.046
body morphogenesisGO:001017120.045
positive regulation of secretion by cellGO:1903532200.045
response to bacteriumGO:00096171980.045
dna metabolic processGO:00062592270.045
regulation of gtpase activityGO:0043087440.044
positive regulation of phosphate metabolic processGO:00459371390.044
purine ribonucleoside metabolic processGO:00461281270.044
regulation of developmental growthGO:00486381740.043
cytokinesisGO:0000910900.042
purine nucleoside catabolic processGO:00061521120.042
regulation of nucleoside metabolic processGO:0009118500.042
organonitrogen compound metabolic processGO:19015643180.041
regulation of gtp catabolic processGO:0033124440.041
photoreceptor cell differentiationGO:00465301700.041
epithelial cell differentiationGO:00308553220.041
detection of light stimulusGO:0009583580.041
organophosphate metabolic processGO:00196371950.041
nucleoside triphosphate catabolic processGO:00091431080.040
regulation of neuromuscular synaptic transmissionGO:1900073150.039
cytoplasmic transportGO:00164821300.039
glycosyl compound metabolic processGO:19016571270.039
regulation of molecular functionGO:00650092170.039
stem cell proliferationGO:0072089880.039
secretionGO:00469031090.038
oocyte anterior posterior axis specificationGO:0007314720.038
ribonucleoside metabolic processGO:00091191270.038
nitrogen compound transportGO:0071705850.037
Mouse
rna processingGO:00063961470.037
glycosyl compound catabolic processGO:19016581120.036
positive regulation of secretionGO:0051047220.036
single organism behaviorGO:00447083910.036
salivary gland histolysisGO:0035070880.036
response to glucoseGO:000974920.035
learning or memoryGO:00076111410.035
negative regulation of growthGO:0045926840.034
ribonucleoside triphosphate catabolic processGO:00092031080.034
cognitionGO:00508901410.034
maternal determination of anterior posterior axis embryoGO:0008358740.034
compound eye morphogenesisGO:00017452490.034
ribonucleotide metabolic processGO:00092591450.034
negative regulation of stem cell proliferationGO:2000647300.034
vesicle fusionGO:0006906190.034
memoryGO:0007613940.033
salivary gland morphogenesisGO:00074351450.033
heterocycle catabolic processGO:00467001660.033
nucleoside metabolic processGO:00091161270.033
sensory perception of chemical stimulusGO:00076061160.033
lipid metabolic processGO:00066291210.032
phototransductionGO:0007602520.031
nucleobase containing small molecule metabolic processGO:00550861740.031
axon guidanceGO:00074112330.031
oocyte axis specificationGO:00073091080.031
detection of stimulusGO:00516061560.031
gland morphogenesisGO:00226121450.031
negative regulation of response to stimulusGO:00485852580.030
positive regulation of cell communicationGO:00106472500.030
ribonucleoside catabolic processGO:00424541120.030
regulation of cell developmentGO:00602842150.030
purine nucleotide catabolic processGO:00061951090.030
regulation of organelle organizationGO:00330431960.030
regulation of hydrolase activityGO:0051336970.030
purine containing compound catabolic processGO:00725231120.029
regulation of embryonic pattern specificationGO:1902875270.029
regulation of intracellular transportGO:0032386640.029
spindle organizationGO:00070512530.029
cellular component assembly involved in morphogenesisGO:00109271510.029
ribonucleotide catabolic processGO:00092611090.029
positive regulation of synaptic transmissionGO:0050806150.028
small molecule metabolic processGO:00442813050.028
notch signaling pathwayGO:00072191200.028
blastoderm segmentationGO:00073501590.028
cellular catabolic processGO:00442483720.028
digestive tract developmentGO:00485651490.028
cell proliferationGO:00082832990.028
gland developmentGO:00487321910.028
macromolecular complex assemblyGO:00650032560.027
rhabdomere developmentGO:0042052380.027
regulation of intracellular signal transductionGO:19025312360.027
neuron projection guidanceGO:00974852410.027
stem cell developmentGO:0048864790.027
organelle assemblyGO:00709251980.027
instar larval developmentGO:0002168550.027
protein modification processGO:00362114380.027
cellular protein modification processGO:00064644380.026
metarhodopsin inactivationGO:001606050.026
endomembrane system organizationGO:00102561190.026
positive regulation of protein metabolic processGO:00512471280.026
purine nucleoside triphosphate catabolic processGO:00091461080.026
response to organic substanceGO:00100332840.025
regulation of synaptic vesicle endocytosisGO:190024270.025
regulation of nucleotide catabolic processGO:0030811480.025
nuclear transportGO:0051169720.025
dopamine receptor signaling pathwayGO:000721240.025
establishment of tissue polarityGO:0007164870.025
developmental maturationGO:00217001720.025
hindgut developmentGO:0061525580.025
positive regulation of phosphorus metabolic processGO:00105621390.024
organic cyclic compound catabolic processGO:19013611680.024
columnar cuboidal epithelial cell developmentGO:00020662490.024
purine ribonucleotide metabolic processGO:00091501450.024
multi organism reproductive behaviorGO:00447051210.024
cell recognitionGO:00080371020.024
organic acid metabolic processGO:00060821030.024
response to oxygen containing compoundGO:19017002000.024
protein phosphorylationGO:00064681690.024
organic substance catabolic processGO:19015753080.024
cell projection assemblyGO:0030031940.023
gtp catabolic processGO:0006184720.023
carboxylic acid metabolic processGO:0019752920.023
regulation of phosphorus metabolic processGO:00511742100.023
anterior posterior axis specification embryoGO:00085951030.023
positive regulation of hydrolase activityGO:0051345780.023
intracellular transportGO:00469072280.023
embryo development ending in birth or egg hatchingGO:00097921520.023
biological adhesionGO:00226101380.023
phagocytosisGO:00069092150.023
tissue migrationGO:00901301550.023
regulation of protein import into nucleusGO:0042306280.022
response to biotic stimulusGO:00096072940.022
neural precursor cell proliferationGO:0061351750.022
response to woundingGO:0009611940.022
ameboidal type cell migrationGO:00016671510.022
axon developmentGO:00615642970.022
tissue morphogenesisGO:00487292970.021
meiotic nuclear divisionGO:00071261510.021
nucleotide catabolic processGO:00091661090.021
organic hydroxy compound metabolic processGO:1901615830.021
axis specificationGO:00097981670.021
centrosome organizationGO:00512971630.021
embryonic morphogenesisGO:00485982060.021
neuron cell cell adhesionGO:000715810.021
embryonic axis specificationGO:00005781070.021
gtp metabolic processGO:0046039720.021
histolysisGO:00075591020.020
negative regulation of signal transductionGO:00099682060.020
muscle cell developmentGO:0055001500.020
positive regulation of cellular component organizationGO:00511301560.020
epithelial cell migrationGO:00106311480.020
macromolecule deacylationGO:0098732110.020
positive regulation of exocytosisGO:004592140.020
regulation of phosphate metabolic processGO:00192202100.020
negative regulation of developmental growthGO:0048640640.020
dephosphorylationGO:0016311510.020
phosphorylationGO:00163102940.020
guanosine containing compound metabolic processGO:1901068740.020
ion transmembrane transportGO:00342201220.020
stem cell divisionGO:0017145690.020
positive regulation of catalytic activityGO:00430851180.020
regulation of autophagyGO:0010506620.019
regulation of pathway restricted smad protein phosphorylationGO:006039310.019
response to external biotic stimulusGO:00432072930.019
nucleoside phosphate metabolic processGO:00067531620.019
purine containing compound metabolic processGO:00725211550.019
cell cell signaling involved in cell fate commitmentGO:00451682100.019
positive regulation of purine nucleotide metabolic processGO:1900544550.019
regulation of protein kinase a signalingGO:001073820.019
tube morphogenesisGO:00352391910.019
aromatic compound catabolic processGO:00194391660.019
positive regulation of synapse assemblyGO:0051965290.018
positive regulation of cellular protein metabolic processGO:00322701180.018
rna localizationGO:00064031150.018
nucleobase containing compound catabolic processGO:00346551650.018
positive regulation of molecular functionGO:00440931360.018
autophagyGO:00069141080.018
defense response to bacteriumGO:00427421780.018
terminal button organizationGO:0072553190.018
protein complex assemblyGO:00064612000.018
positive regulation of ras gtpase activityGO:0032320360.018
regulation of protein localization to nucleusGO:1900180290.018
detection of external stimulusGO:0009581660.018
regulation of cytoplasmic transportGO:1903649470.018
muscle structure developmentGO:00610612240.018
positive regulation of gtp catabolic processGO:0033126430.017
response to hexoseGO:000974630.017
cell cycle arrestGO:000705040.017
mesenchymal cell developmentGO:001403110.017
actin cytoskeleton organizationGO:00300362060.017
positive regulation of cellular amine metabolic processGO:003324000.017
organelle fissionGO:00482853400.017
mesenchymal cell differentiationGO:004876210.017
cytoskeleton dependent cytokinesisGO:0061640810.017
regulation of neurogenesisGO:00507671580.017
negative regulation of epithelial cell proliferationGO:005068040.017
lipid localizationGO:0010876540.016
cellular macromolecule localizationGO:00707272200.016
dopamine biosynthetic processGO:004241630.016
epithelial cell developmentGO:00020642740.016
regulation of necrotic cell deathGO:001093910.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
regulation of synaptic vesicle transportGO:1902803100.016
germarium derived egg chamber formationGO:00072931010.016
regulation of protein stabilityGO:0031647430.016
single organism intracellular transportGO:19025822070.016
regulation of cellular ketone metabolic processGO:001056530.016
nucleocytoplasmic transportGO:0006913720.016
molting cycle chitin based cuticleGO:0007591560.016
positive regulation of programmed cell deathGO:0043068620.016
cellular protein complex assemblyGO:0043623710.016
cellular response to endogenous stimulusGO:0071495800.016
extrinsic apoptotic signaling pathwayGO:009719110.016
mitotic spindle organizationGO:00070522200.015
cellular response to organic substanceGO:00713101320.015
inorganic cation transmembrane transportGO:0098662610.015
purine ribonucleotide catabolic processGO:00091541090.015
matingGO:00076181200.015
single organism cell adhesionGO:0098602470.015
regulation of response to external stimulusGO:00321011150.015
establishment of protein localizationGO:00451841630.015
epithelium migrationGO:00901321480.015
myotube cell developmentGO:001490430.015
positive regulation of neurotransmitter secretionGO:000195620.015
pigmentationGO:0043473750.015
single organismal cell cell adhesionGO:0016337450.015
establishment or maintenance of cell polarityGO:00071631670.015
regulation of cell maturationGO:1903429270.015
positive regulation of cellular biosynthetic processGO:00313283160.015
ras protein signal transductionGO:0007265880.015
microtubule based transportGO:0010970420.015
ncrna metabolic processGO:0034660430.015
regulation of purine nucleotide biosynthetic processGO:1900371140.015
tube developmentGO:00352952440.015
positive regulation of cell deathGO:0010942690.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
protein dephosphorylationGO:0006470270.015
rho protein signal transductionGO:0007266140.014
atp biosynthetic processGO:000675420.014
catecholamine biosynthetic processGO:004242330.014
negative regulation of neuromuscular synaptic transmissionGO:190007470.014
anterior posterior axis specificationGO:00099481090.014
apoptotic processGO:00069151590.014
cellular macromolecular complex assemblyGO:00346221530.014
purine nucleoside metabolic processGO:00422781270.014
chromosome organizationGO:00512763600.014
negative regulation of cellular metabolic processGO:00313243820.014
digestive system developmentGO:00551231490.014
regulation of programmed cell deathGO:00430671520.014
protein import into nucleusGO:0006606510.014
establishment of spindle localizationGO:0051293220.014
meiotic cell cycle processGO:19030461320.014
detection of chemical stimulusGO:0009593930.014
positive regulation of catabolic processGO:00098961050.014
salivary gland developmentGO:00074311620.013
ovarian follicle cell developmentGO:00307072480.013
morphogenesis of a polarized epitheliumGO:0001738930.013
ribose phosphate metabolic processGO:00196931450.013
positive regulation of nfat protein import into nucleusGO:0051533160.013
peptidyl threonine modificationGO:001821030.013
cellular amino acid metabolic processGO:0006520610.013
morphogenesis of follicular epitheliumGO:0016333360.013
epidermal growth factor receptor signaling pathwayGO:0007173580.013
compound eye photoreceptor cell differentiationGO:00017511400.013
amine metabolic processGO:0009308120.013
embryonic development via the syncytial blastodermGO:00017001480.013
single organism carbohydrate metabolic processGO:0044723720.013
positive regulation of endocytosisGO:0045807220.013
positive regulation of protein secretionGO:005071490.013
neurotransmitter metabolic processGO:004213320.013
single organism biosynthetic processGO:00447112060.013
synaptic vesicle exocytosisGO:0016079160.013
synaptic transmission cholinergicGO:000727190.013
regulation of protein localizationGO:0032880760.013
response to sterolGO:0036314340.013
exocytosisGO:0006887280.012
establishment of planar polarityGO:0001736870.012
negative regulation of immune system processGO:0002683500.012
molting cycleGO:0042303560.012
cytoplasm organizationGO:0007028640.012
connective tissue developmentGO:006144830.012
spindle localizationGO:0051653220.012
positive regulation of gtpase activityGO:0043547430.012
positive regulation of neuron apoptotic processGO:004352510.012
positive regulation of cellular amide metabolic processGO:0034250260.012
exocrine system developmentGO:00352721620.012
negative regulation of phosphorylationGO:0042326350.012
regulation of protein phosphorylationGO:0001932640.012
negative regulation of catabolic processGO:0009895360.012
cell divisionGO:00513012480.012
autophagic vacuole assemblyGO:000004520.012
inositol lipid mediated signalingGO:004801740.012
necrotic cell deathGO:007026510.012
lateral inhibitionGO:00463312060.012
positive regulation of protein transportGO:0051222370.012
intracellular mrna localizationGO:0008298660.012
mitotic sister chromatid segregationGO:0000070870.012
cuticle developmentGO:0042335860.012
apoptotic signaling pathwayGO:0097190270.012
regulation of terminal button organizationGO:2000331110.011
organ growthGO:0035265560.011
regulation of synapse maturationGO:009012810.011
regulation of epithelial cell proliferationGO:005067840.011
mapk cascadeGO:00001651070.011
regulation of protein targetingGO:1903533290.011
regulation of synaptic vesicle exocytosisGO:200030030.011
protein transportGO:00150311550.011
catechol containing compound metabolic processGO:0009712100.011
positive regulation of intracellular transportGO:0032388420.011
nucleoside phosphate catabolic processGO:19012921100.011
positive regulation of response to stimulusGO:00485843230.011
synaptic transmission dopaminergicGO:000196320.011
phenol containing compound metabolic processGO:0018958570.011
response to heatGO:0009408630.011
asymmetric neuroblast divisionGO:0055059330.011
neurotransmitter secretionGO:0007269350.011
regulation of nucleotide metabolic processGO:0006140620.011
reproductive system developmentGO:0061458740.011
male courtship behaviorGO:0008049630.011
cytoskeletal matrix organization at active zoneGO:004878950.011
establishment of spindle orientationGO:0051294180.011
neuron recognitionGO:00080381010.011
cellular response to biotic stimulusGO:007121640.011
positive regulation of phosphorylationGO:0042327870.011
regulation of intracellular protein transportGO:0033157460.011
cellular response to molecule of bacterial originGO:007121930.011
sodium ion transportGO:0006814220.011
catechol containing compound biosynthetic processGO:000971330.011
response to nitrogen compoundGO:1901698900.011
negative regulation of cellular catabolic processGO:0031330340.011
regulation of secretionGO:0051046440.011
intracellular protein transportGO:00068861040.011
developmental growth involved in morphogenesisGO:0060560650.010
imaginal disc growthGO:0007446370.010
chromosome segregationGO:00070591570.010
action potentialGO:0001508130.010
innate immune responseGO:00450871440.010
hindgut morphogenesisGO:0007442580.010
mushroom body developmentGO:0016319700.010
macromolecule catabolic processGO:00090571610.010
visual learningGO:000854240.010
regulation of notch signaling pathwayGO:00085931000.010
positive regulation of cellular catabolic processGO:0031331950.010
response to calcium ionGO:005159210.010
nucleus organizationGO:0006997450.010
purine nucleoside biosynthetic processGO:004245130.010
actin filament based movementGO:0030048260.010
endoderm formationGO:000170630.010
negative regulation of nucleobase containing compound metabolic processGO:00459342610.010
chitin based cuticle developmentGO:0040003490.010
actomyosin structure organizationGO:0031032560.010
carbohydrate derivative metabolic processGO:19011352170.010

cpx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
organ system cancerDOID:005068600.011