IMP: Integrative Multi-species Prediction

Drosophila melanogaster

15 known processes

eIF2B-beta (Dmel_CG2677)

CG2677 gene product from transcript CG2677-RA

(Aliases: DMC100G10.3,EG:100G10.3,Dmel\CG2677,CG2677,eIF2Bbeta)

FLYBASE: FBgn0024996
Entrez: 31256
UniProtKB: O76863

Process Predictions
Disease Predictions

eIF2B-beta biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
single organism biosynthetic process	GO:0044711	206	0.134
positive regulation of response to stimulus	GO:0048584	323	0.113
cell death	GO:0008219	279	0.086
vesicle mediated transport	GO:0016192	381	0.085
positive regulation of phosphate metabolic process	GO:0045937	139	0.078
single organism intracellular transport	GO:1902582	207	0.068
intracellular transport	GO:0046907	228	0.065
positive regulation of signal transduction	GO:0009967	223	0.064
regulation of intracellular signal transduction	GO:1902531	236	0.057
protein dna complex subunit organization	GO:0071824	86	0.048
carbohydrate derivative biosynthetic process	GO:1901137	85	0.046
single organism membrane organization	GO:0044802	93	0.045
endocytosis	GO:0006897	310	0.045
intracellular signal transduction	GO:0035556	300	0.043
growth	GO:0040007	359	0.042
ion transport	GO:0006811	145	0.041
positive regulation of cell communication	GO:0010647	250	0.038
regulation of cell cycle process	GO:0010564	181	0.038
positive regulation of mapk cascade	GO:0043410	63	0.038
organophosphate metabolic process	GO:0019637	195	0.037
rna processing	GO:0006396	147	0.037
organic substance transport	GO:0071702	257	0.037
organonitrogen compound metabolic process	GO:1901564	318	0.035
positive regulation of signaling	GO:0023056	243	0.035
organonitrogen compound biosynthetic process	GO:1901566	117	0.034
lipid metabolic process	GO:0006629	121	0.033
purine nucleotide metabolic process	GO:0006163	146	0.033
purine containing compound biosynthetic process	GO:0072522	30	0.031
membrane organization	GO:0061024	112	0.031
lateral inhibition	GO:0046331	206	0.031
notch signaling pathway	GO:0007219	120	0.031
carbohydrate derivative metabolic process	GO:1901135	217	0.030
small molecule metabolic process	GO:0044281	305	0.030
negative regulation of mitotic cell cycle	GO:0045930	109	0.030
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.028
establishment of localization in cell	GO:0051649	402	0.027
regulation of catalytic activity	GO:0050790	185	0.027
aromatic compound catabolic process	GO:0019439	166	0.026
phagocytosis	GO:0006909	215	0.026
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.026
purine ribonucleoside metabolic process	GO:0046128	127	0.026
ribonucleotide metabolic process	GO:0009259	145	0.025
positive regulation of phosphorus metabolic process	GO:0010562	139	0.025
cytoplasmic transport	GO:0016482	130	0.024
transcription initiation from rna polymerase ii promoter	GO:0006367	25	0.024
macromolecular complex assembly	GO:0065003	256	0.024
nucleoside metabolic process	GO:0009116	127	0.022
positive regulation of cellular biosynthetic process	GO:0031328	316	0.022
amine metabolic process	GO:0009308	12	0.022
chromosome organization	GO:0051276	360	0.022
nucleoside monophosphate metabolic process	GO:0009123	52	0.021
regulation of molecular function	GO:0065009	217	0.020
regulation of notch signaling pathway	GO:0008593	100	0.020
transmembrane transport	GO:0055085	139	0.020
positive regulation of phosphorylation	GO:0042327	87	0.020
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.020
positive regulation of intracellular signal transduction	GO:1902533	116	0.019
gene silencing	GO:0016458	138	0.019
protein modification process	GO:0036211	438	0.019
embryo development ending in birth or egg hatching	GO:0009792	152	0.019
glycosyl compound metabolic process	GO:1901657	127	0.018
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.018
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.018
purine nucleotide biosynthetic process	GO:0006164	29	0.017
atp metabolic process	GO:0046034	49	0.017
organic substance catabolic process	GO:1901575	308	0.017
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.017
nucleoside triphosphate metabolic process	GO:0009141	120	0.017
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.016
positive regulation of macromolecule metabolic process	GO:0010604	405	0.016
purine ribonucleotide metabolic process	GO:0009150	145	0.016
cellular response to dna damage stimulus	GO:0006974	223	0.016
secretion	GO:0046903	109	0.016
glycosyl compound biosynthetic process	GO:1901659	3	0.015
organophosphate biosynthetic process	GO:0090407	46	0.015
ribose phosphate metabolic process	GO:0019693	145	0.015
regulation of mitotic cell cycle	GO:0007346	190	0.015
translation	GO:0006412	69	0.015
purine containing compound metabolic process	GO:0072521	155	0.015
gland development	GO:0048732	191	0.015
negative regulation of cellular metabolic process	GO:0031324	382	0.014
transcription from rna polymerase ii promoter	GO:0006366	368	0.014
eye pigment metabolic process	GO:0042441	33	0.014
purine nucleoside metabolic process	GO:0042278	127	0.014
regulation of phosphorus metabolic process	GO:0051174	210	0.013
phosphorylation	GO:0016310	294	0.013
rna localization	GO:0006403	115	0.013
mapk cascade	GO:0000165	107	0.013
positive regulation of molecular function	GO:0044093	136	0.013
ribosomal large subunit biogenesis	GO:0042273	1	0.013
response to organic substance	GO:0010033	284	0.012
pigmentation	GO:0043473	75	0.012
protein complex assembly	GO:0006461	200	0.012
cellular protein modification process	GO:0006464	438	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.012
nitrogen compound transport	GO:0071705	85	0.012
regulation of gene expression epigenetic	GO:0040029	128	0.012
dna templated transcription initiation	GO:0006352	25	0.012
regulation of phosphate metabolic process	GO:0019220	210	0.012
central nervous system development	GO:0007417	201	0.011
dephosphorylation	GO:0016311	51	0.011
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.011
posttranscriptional gene silencing	GO:0016441	46	0.011
death	GO:0016265	284	0.011
oxoacid metabolic process	GO:0043436	103	0.011
cellular response to chemical stimulus	GO:0070887	199	0.011
nucleoside phosphate metabolic process	GO:0006753	162	0.011
nucleobase containing small molecule metabolic process	GO:0055086	174	0.011
regulation of mapk cascade	GO:0043408	92	0.011
lipid localization	GO:0010876	54	0.011
multi organism reproductive behavior	GO:0044705	121	0.010
chromosome segregation	GO:0007059	157	0.010
secretion by cell	GO:0032940	101	0.010
cellular lipid metabolic process	GO:0044255	83	0.010
cell cycle phase transition	GO:0044770	140	0.010
sister chromatid segregation	GO:0000819	92	0.010
positive regulation of biosynthetic process	GO:0009891	316	0.010
body morphogenesis	GO:0010171	2	0.010
regulation of nuclear division	GO:0051783	58	0.010
establishment of protein localization	GO:0045184	163	0.010
purine nucleoside biosynthetic process	GO:0042451	3	0.010
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.010
cellular amino acid metabolic process	GO:0006520	61	0.010
negative regulation of cellular protein metabolic process	GO:0032269	85	0.010

eIF2B-beta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.014

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