Drosophila melanogaster

131 known processes

MED27 (Dmel_CG1245)

Mediator complex subunit 27

(Aliases: CRSP34,dCRSP34,dCrsp34,Med27,Trap37,med27,CG1245,dTRAP37,Dmel\CG1245)

MED27 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of neural precursor cell proliferationGO:2000178270.983
negative regulation of stem cell proliferationGO:2000647300.983
regulation of neural precursor cell proliferationGO:2000177350.927
stem cell proliferationGO:0072089880.907
neural precursor cell proliferationGO:0061351750.852
regulation of cell developmentGO:00602842150.821
regulation of neuroblast proliferationGO:1902692340.787
regulation of stem cell proliferationGO:0072091400.783
neuroblast proliferationGO:0007405740.760
negative regulation of neuroblast proliferationGO:0007406270.635
regulation of multicellular organismal developmentGO:20000264140.569
regulation of neurogenesisGO:00507671580.564
cell proliferationGO:00082832990.558
negative regulation of neurogenesisGO:0050768530.540
negative regulation of cell differentiationGO:00455961430.523
regulation of nervous system developmentGO:00519602480.507
negative regulation of cell developmentGO:0010721620.466
transcription from rna polymerase ii promoterGO:00063663680.386
negative regulation of developmental processGO:00510932010.381
regulation of cell differentiationGO:00455953020.323
regulation of cell proliferationGO:00421271630.191
negative regulation of nervous system developmentGO:0051961920.184
programmed cell deathGO:00125012570.183
deathGO:00162652840.182
response to abiotic stimulusGO:00096283410.174
regulation of programmed cell deathGO:00430671520.172
organelle fissionGO:00482853400.164
regulation of cell deathGO:00109411730.148
cell deathGO:00082192790.147
central nervous system developmentGO:00074172010.142
cell cycle checkpointGO:0000075950.133
cellular catabolic processGO:00442483720.127
regulation of transcription from rna polymerase ii promoterGO:00063573780.122
positive regulation of nucleobase containing compound metabolic processGO:00459353320.116
telomere maintenanceGO:0000723210.105
dendrite developmentGO:00163582040.102
negative regulation of macromolecule biosynthetic processGO:00105582700.101
regulation of apoptotic processGO:00429811300.101
homeostatic processGO:00425921990.096
response to organic substanceGO:00100332840.089
dna damage checkpointGO:0000077780.088
apoptotic processGO:00069151590.088
growthGO:00400073590.088
response to oxygen containing compoundGO:19017002000.085
small molecule metabolic processGO:00442813050.083
chromosome organizationGO:00512763600.082
regulation of localizationGO:00328792750.080
negative regulation of multicellular organismal processGO:00512411420.079
negative regulation of mitotic cell cycleGO:00459301090.079
positive regulation of nucleic acid templated transcriptionGO:19035082660.077
organic substance catabolic processGO:19015753080.074
cellular response to uvGO:0034644120.072
negative regulation of programmed cell deathGO:0043069720.071
cellular response to dna damage stimulusGO:00069742230.071
positive regulation of gene expressionGO:00106282900.070
protein transportGO:00150311550.069
negative regulation of cell cycle processGO:00109481090.066
histone h3 k4 methylationGO:0051568160.066
centrosome cycleGO:00070981370.065
positive regulation of cellular biosynthetic processGO:00313283160.064
catabolic processGO:00090564090.063
regulation of immune system processGO:00026821760.063
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.060
spermatogenesisGO:00072832000.060
response to heatGO:0009408630.060
intracellular steroid hormone receptor signaling pathwayGO:0030518120.060
mushroom body developmentGO:0016319700.060
response to biotic stimulusGO:00096072940.060
mitotic dna damage checkpointGO:0044773740.060
negative regulation of gene expressionGO:00106293870.058
developmental maturationGO:00217001720.057
mitotic nuclear divisionGO:00070672130.056
positive regulation of nitrogen compound metabolic processGO:00511733540.056
organophosphate metabolic processGO:00196371950.053
dna integrity checkpointGO:0031570810.052
embryonic pattern specificationGO:00098801740.052
regulation of cell cycle processGO:00105641810.049
brain developmentGO:00074201200.049
oxoacid metabolic processGO:00434361030.046
negative regulation of cell proliferationGO:0008285690.045
chromosome segregationGO:00070591570.044
cellular response to chemical stimulusGO:00708871990.043
mitotic dna integrity checkpointGO:0044774750.043
cell maturationGO:00484691440.042
positive regulation of programmed cell deathGO:0043068620.042
nuclear divisionGO:00002803320.041
organonitrogen compound metabolic processGO:19015643180.041
dendrite morphogenesisGO:00488131990.041
mitotic cell cycle phase transitionGO:00447721380.040
regulation of gene expression epigeneticGO:00400291280.040
negative regulation of cell cycle phase transitionGO:19019881030.037
mitotic g2 m transition checkpointGO:0044818700.037
negative regulation of cell deathGO:0060548810.037
response to temperature stimulusGO:00092661060.036
regulation of cell cycle phase transitionGO:19019871300.036
regulation of proteolysisGO:0030162870.036
regulation of cellular amine metabolic processGO:003323830.035
dna repairGO:0006281540.035
regionalizationGO:00030024160.035
embryo development ending in birth or egg hatchingGO:00097921520.035
telomere organizationGO:0032200210.035
chromatin organizationGO:00063252070.035
cellular response to radiationGO:0071478520.034
positive regulation of transcription dna templatedGO:00458932660.034
heterocycle catabolic processGO:00467001660.033
head developmentGO:00603221350.033
synapse organizationGO:00508081960.032
nucleobase containing compound catabolic processGO:00346551650.032
endocytosisGO:00068973100.032
positive regulation of macromolecule biosynthetic processGO:00105572830.031
cellular protein modification processGO:00064644380.031
organic cyclic compound catabolic processGO:19013611680.031
cellular nitrogen compound catabolic processGO:00442701650.031
negative regulation of cellular metabolic processGO:00313243820.031
phosphorylationGO:00163102940.031
positive regulation of rna metabolic processGO:00512542710.030
regulation of transportGO:00510491810.030
wnt signaling pathwayGO:0016055980.029
protein modification processGO:00362114380.029
negative regulation of mitotic cell cycle phase transitionGO:19019911030.028
developmental pigmentationGO:0048066680.028
muscle structure developmentGO:00610612240.028
exocrine system developmentGO:00352721620.028
negative regulation of apoptotic processGO:0043066630.028
cell divisionGO:00513012480.028
regulation of catalytic activityGO:00507901850.028
developmental programmed cell deathGO:00106231380.028
regulation of cellular protein metabolic processGO:00322682430.026
regulation of mitotic cell cycleGO:00073461900.026
carboxylic acid metabolic processGO:0019752920.026
response to bacteriumGO:00096171980.026
regulation of cell projection organizationGO:0031344920.025
male gamete generationGO:00482322010.025
vesicle mediated transportGO:00161923810.025
regulation of mitotic cell cycle phase transitionGO:19019901300.025
sister chromatid segregationGO:0000819920.024
mitotic g2 dna damage checkpointGO:0007095690.024
cytokinesisGO:0000910900.024
immune system processGO:00023763470.024
centrosome duplicationGO:00512981210.023
response to endogenous stimulusGO:00097191190.023
single organism biosynthetic processGO:00447112060.023
positive regulation of rna biosynthetic processGO:19026802660.022
pigment metabolic process involved in developmental pigmentationGO:0043324330.022
response to organic cyclic compoundGO:0014070890.022
covalent chromatin modificationGO:00165691060.022
nucleoside phosphate metabolic processGO:00067531620.021
protein localizationGO:00081042840.021
peptidyl amino acid modificationGO:00181931050.021
protein maturationGO:0051604710.021
response to nitrogen compoundGO:1901698900.021
negative regulation of cell cycleGO:00457861160.021
regulation of molecular functionGO:00650092170.020
sex comb developmentGO:004549880.020
negative regulation of nitrogen compound metabolic processGO:00511722650.020
anatomical structure homeostasisGO:0060249970.020
positive regulation of macromolecule metabolic processGO:00106044050.020
positive regulation of apoptotic signaling pathwayGO:200123540.020
dna metabolic processGO:00062592270.020
cellular amine metabolic processGO:0044106120.020
cellular response to oxygen containing compoundGO:1901701790.020
amine metabolic processGO:0009308120.020
negative regulation of cellular protein metabolic processGO:0032269850.020
imaginal disc derived appendage morphogenesisGO:00351143950.020
nucleoside triphosphate catabolic processGO:00091431080.019
chromatin modificationGO:00165681470.019
cellular macromolecule catabolic processGO:00442651360.019
meiotic sister chromatid segregationGO:004514460.018
cellular response to abiotic stimulusGO:0071214580.018
organic substance transportGO:00717022570.018
gland developmentGO:00487321910.018
cell cycle phase transitionGO:00447701400.018
response to external biotic stimulusGO:00432072930.018
positive regulation of molecular functionGO:00440931360.018
appendage morphogenesisGO:00351073970.018
maintenance of locationGO:0051235730.018
epithelial cell differentiationGO:00308553220.018
negative regulation of rna biosynthetic processGO:19026792400.018
appendage developmentGO:00487364010.018
response to ecdysoneGO:0035075340.018
regulation of cell cycleGO:00517262910.017
protein complex biogenesisGO:00702712010.017
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.017
salivary gland developmentGO:00074311620.017
reproductive structure developmentGO:0048608740.017
response to other organismGO:00517072930.017
single organism intracellular transportGO:19025822070.017
positive regulation of cell deathGO:0010942690.017
negative regulation of response to stimulusGO:00485852580.017
positive regulation of cellular component organizationGO:00511301560.016
cell recognitionGO:00080371020.016
embryonic axis specificationGO:00005781070.016
protein alkylationGO:0008213430.016
gene silencingGO:00164581380.016
dna recombinationGO:0006310320.016
negative regulation of nucleobase containing compound metabolic processGO:00459342610.016
negative regulation of cell communicationGO:00106482230.016
nucleotide metabolic processGO:00091171610.016
positive regulation of transportGO:0051050920.016
oocyte dorsal ventral axis specificationGO:0007310340.016
response to light stimulusGO:00094161240.016
regulation of response to stressGO:00801342000.015
positive regulation of lipid metabolic processGO:004583440.015
phagocytosisGO:00069092150.015
negative regulation of signal transductionGO:00099682060.015
actin filament based processGO:00300292200.015
purine ribonucleotide metabolic processGO:00091501450.015
organic acid metabolic processGO:00060821030.015
body morphogenesisGO:001017120.015
meiotic chromosome segregationGO:0045132590.015
negative regulation of biosynthetic processGO:00098902770.014
cell motilityGO:00488702510.014
ribonucleoside catabolic processGO:00424541120.014
multicellular organismal reproductive behaviorGO:00330571100.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
anterior posterior axis specification embryoGO:00085951030.014
meiotic cell cycleGO:00513211710.014
protein processingGO:0016485680.014
single organism catabolic processGO:00447122280.014
mrna catabolic processGO:0006402330.014
neuromuscular junction developmentGO:00075281490.014
macromolecular complex assemblyGO:00650032560.013
histone methylationGO:0016571400.013
lipid localizationGO:0010876540.013
eye pigment biosynthetic processGO:0006726320.013
establishment of localization in cellGO:00516494020.013
cellular amino acid metabolic processGO:0006520610.013
defense response to bacteriumGO:00427421780.013
positive regulation of cellular catabolic processGO:0031331950.013
salivary gland morphogenesisGO:00074351450.013
regulation of meiosisGO:004002030.013
lipid storageGO:0019915380.013
regulation of chromosome organizationGO:0033044640.013
cellular response to organic substanceGO:00713101320.013
pigment biosynthetic processGO:0046148360.013
positive regulation of apoptotic processGO:0043065470.013
positive regulation of response to stimulusGO:00485843230.013
posttranscriptional gene silencing by rnaGO:0035194450.012
centrosome organizationGO:00512971630.012
meiotic cell cycle processGO:19030461320.012
oocyte developmentGO:00485991240.012
regulation of cellular catabolic processGO:00313291570.012
organelle assemblyGO:00709251980.012
negative regulation of transcription dna templatedGO:00458922370.012
receptor mediated endocytosisGO:0006898210.012
camera type eye developmentGO:004301040.011
cellular macromolecule localizationGO:00707272200.011
response to uvGO:0009411240.011
protein ubiquitinationGO:0016567700.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
purine nucleoside monophosphate metabolic processGO:0009126500.011
response to radiationGO:00093141550.011
ribonucleotide catabolic processGO:00092611090.011
g2 dna damage checkpointGO:0031572690.011
histone lysine methylationGO:0034968320.011
gland morphogenesisGO:00226121450.011
autophagic cell deathGO:0048102830.011
mitotic cytokinesisGO:0000281500.011
cytoplasmic transportGO:00164821300.011
membrane organizationGO:00610241120.011
regulation of innate immune responseGO:0045088710.011
multi organism reproductive behaviorGO:00447051210.011
neuronal stem cell divisionGO:0036445350.011
macromolecule catabolic processGO:00090571610.011
regulation of cellular amino acid metabolic processGO:000652100.011
positive regulation of biosynthetic processGO:00098913160.011
cellular protein localizationGO:00346131600.010
regulation of cellular component biogenesisGO:00440872010.010
aromatic compound catabolic processGO:00194391660.010
proteolysisGO:00065081920.010
imaginal disc derived wing morphogenesisGO:00074763370.010
agingGO:00075681430.010
tripartite regional subdivisionGO:00073511030.010
regulation of cellular localizationGO:00603411360.010
negative regulation of signalingGO:00230572190.010
muscle organ developmentGO:00075171270.010

MED27 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.017
central nervous system diseaseDOID:33100.013