| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.976 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.960 | |
| negative regulation of transcription dna templated | GO:0045892 | 237 | 0.957 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.926 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.903 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.866 | Yeast |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.833 | Yeast |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.830 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 240 | 0.767 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.710 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.704 | Yeast |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.670 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.638 | Yeast |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.623 | Yeast |
| negative regulation of gene expression | GO:0010629 | 387 | 0.599 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.572 | Yeast |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 240 | 0.558 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.552 | Yeast |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.502 | Yeast |
| regulation of gene silencing | GO:0060968 | 63 | 0.442 | |
| positive regulation of gene expression | GO:0010628 | 290 | 0.421 | Yeast |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.421 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.395 | Yeast |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 119 | 0.387 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.386 | Yeast |
| nuclear division | GO:0000280 | 332 | 0.369 | |
| salivary gland development | GO:0007431 | 162 | 0.348 | |
| chromosome organization | GO:0051276 | 360 | 0.329 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.317 | Yeast |
| salivary gland morphogenesis | GO:0007435 | 145 | 0.314 | |
| gland development | GO:0048732 | 191 | 0.283 | |
| gene silencing | GO:0016458 | 138 | 0.280 | |
| sister chromatid segregation | GO:0000819 | 92 | 0.262 | |
| cell proliferation | GO:0008283 | 299 | 0.224 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.215 | |
| homeostatic process | GO:0042592 | 199 | 0.195 | |
| death | GO:0016265 | 284 | 0.189 | |
| circulatory system development | GO:0072359 | 82 | 0.186 | |
| cell death | GO:0008219 | 279 | 0.185 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 77 | 0.182 | |
| imaginal disc derived appendage development | GO:0048737 | 399 | 0.178 | |
| taxis | GO:0042330 | 304 | 0.169 | |
| gland morphogenesis | GO:0022612 | 145 | 0.168 | |
| response to abiotic stimulus | GO:0009628 | 341 | 0.162 | |
| cell migration | GO:0016477 | 238 | 0.159 | |
| exocrine system development | GO:0035272 | 162 | 0.155 | |
| response to alcohol | GO:0097305 | 95 | 0.150 | |
| response to biotic stimulus | GO:0009607 | 294 | 0.141 | |
| epithelium migration | GO:0090132 | 148 | 0.130 | |
| programmed cell death | GO:0012501 | 257 | 0.126 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.125 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.125 | Yeast |
| cellular protein modification process | GO:0006464 | 438 | 0.120 | |
| histolysis | GO:0007559 | 102 | 0.116 | |
| tissue migration | GO:0090130 | 155 | 0.113 | |
| oxoacid metabolic process | GO:0043436 | 103 | 0.113 | |
| ameboidal type cell migration | GO:0001667 | 151 | 0.112 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 80 | 0.109 | |
| mitotic cell cycle phase transition | GO:0044772 | 138 | 0.107 | |
| regulation of chromatin silencing | GO:0031935 | 36 | 0.107 | |
| imaginal disc derived appendage morphogenesis | GO:0035114 | 395 | 0.106 | |
| mitotic sister chromatid segregation | GO:0000070 | 87 | 0.106 | |
| organelle fission | GO:0048285 | 340 | 0.106 | |
| chromatin modification | GO:0016568 | 147 | 0.103 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.096 | Yeast |
| muscle structure development | GO:0061061 | 224 | 0.093 | |
| regulation of cell proliferation | GO:0042127 | 163 | 0.085 | |
| salivary gland cell autophagic cell death | GO:0035071 | 83 | 0.084 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.080 | |
| stem cell differentiation | GO:0048863 | 117 | 0.079 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.079 | |
| regulation of gene expression epigenetic | GO:0040029 | 128 | 0.074 | |
| carboxylic acid metabolic process | GO:0019752 | 92 | 0.074 | |
| chromatin silencing | GO:0006342 | 76 | 0.074 | |
| mitotic cell cycle embryonic | GO:0045448 | 38 | 0.069 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.069 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.069 | |
| regulation of molecular function | GO:0065009 | 217 | 0.067 | |
| developmental programmed cell death | GO:0010623 | 138 | 0.067 | |
| embryonic morphogenesis | GO:0048598 | 206 | 0.065 | |
| wing disc morphogenesis | GO:0007472 | 344 | 0.063 | |
| camera type eye development | GO:0043010 | 4 | 0.061 | Zebrafish |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 0 | 0.059 | |
| cellular amine metabolic process | GO:0044106 | 12 | 0.057 | |
| regulation of chromosome organization | GO:0033044 | 64 | 0.057 | |
| protein modification process | GO:0036211 | 438 | 0.057 | |
| morphogenesis of an epithelium | GO:0002009 | 276 | 0.056 | |
| organelle localization | GO:0051640 | 148 | 0.055 | |
| post embryonic appendage morphogenesis | GO:0035120 | 385 | 0.053 | |
| positive regulation of protein complex assembly | GO:0031334 | 22 | 0.050 | |
| response to organic substance | GO:0010033 | 284 | 0.049 | |
| response to lipopolysaccharide | GO:0032496 | 4 | 0.049 | |
| tissue death | GO:0016271 | 102 | 0.048 | |
| regulation of localization | GO:0032879 | 275 | 0.048 | |
| embryonic development via the syncytial blastoderm | GO:0001700 | 148 | 0.046 | |
| histone modification | GO:0016570 | 106 | 0.045 | |
| autophagic cell death | GO:0048102 | 83 | 0.045 | |
| organic acid metabolic process | GO:0006082 | 103 | 0.045 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.045 | |
| chromosome segregation | GO:0007059 | 157 | 0.044 | |
| regulation of cellular response to stress | GO:0080135 | 89 | 0.044 | |
| dna metabolic process | GO:0006259 | 227 | 0.043 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 3 | 0.043 | |
| histone h3 k4 methylation | GO:0051568 | 16 | 0.042 | |
| covalent chromatin modification | GO:0016569 | 106 | 0.041 | |
| signal transduction by phosphorylation | GO:0023014 | 107 | 0.039 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.039 | |
| phosphorylation | GO:0016310 | 294 | 0.038 | |
| rna localization | GO:0006403 | 115 | 0.038 | |
| regulation of cell cycle phase transition | GO:1901987 | 130 | 0.035 | |
| cell motility | GO:0048870 | 251 | 0.035 | |
| mapk cascade | GO:0000165 | 107 | 0.035 | |
| regulation of cellular amine metabolic process | GO:0033238 | 3 | 0.035 | |
| peptidyl lysine modification | GO:0018205 | 57 | 0.032 | |
| response to other organism | GO:0051707 | 293 | 0.031 | |
| protein secretion | GO:0009306 | 45 | 0.031 | |
| cell adhesion | GO:0007155 | 136 | 0.030 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 130 | 0.030 | |
| mitotic spindle organization | GO:0007052 | 220 | 0.030 | |
| regulation of multicellular organismal development | GO:2000026 | 414 | 0.030 | |
| protein alkylation | GO:0008213 | 43 | 0.030 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.029 | |
| developmental growth | GO:0048589 | 280 | 0.029 | |
| response to light stimulus | GO:0009416 | 124 | 0.029 | |
| striated muscle cell differentiation | GO:0051146 | 90 | 0.029 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 118 | 0.028 | |
| localization of cell | GO:0051674 | 257 | 0.028 | |
| salivary gland histolysis | GO:0035070 | 88 | 0.027 | |
| eye development | GO:0001654 | 323 | 0.027 | Zebrafish |
| intracellular signal transduction | GO:0035556 | 300 | 0.025 | |
| regulation of cell death | GO:0010941 | 173 | 0.025 | |
| camera type eye morphogenesis | GO:0048593 | 2 | 0.025 | |
| establishment of localization in cell | GO:0051649 | 402 | 0.024 | |
| histone lysine methylation | GO:0034968 | 32 | 0.024 | |
| regulation of cell shape | GO:0008360 | 113 | 0.023 | |
| negative regulation of cell proliferation | GO:0008285 | 69 | 0.023 | |
| regulation of organelle organization | GO:0033043 | 196 | 0.023 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.023 | |
| peptidyl amino acid modification | GO:0018193 | 105 | 0.023 | |
| establishment or maintenance of cell polarity | GO:0007163 | 167 | 0.023 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.022 | |
| chromatin organization | GO:0006325 | 207 | 0.022 | |
| chromosome localization | GO:0050000 | 20 | 0.022 | |
| regulation of programmed cell death | GO:0043067 | 152 | 0.022 | |
| stem cell division | GO:0017145 | 69 | 0.021 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.021 | |
| positive regulation of molecular function | GO:0044093 | 136 | 0.021 | |
| regulation of dna metabolic process | GO:0051052 | 34 | 0.021 | |
| epithelial cell migration | GO:0010631 | 148 | 0.021 | |
| tissue morphogenesis | GO:0048729 | 297 | 0.021 | |
| negative regulation of response to stimulus | GO:0048585 | 258 | 0.021 | |
| cellular response to chemical stimulus | GO:0070887 | 199 | 0.021 | Yeast |
| actin cytoskeleton organization | GO:0030036 | 206 | 0.020 | |
| response to bacterium | GO:0009617 | 198 | 0.020 | |
| response to lipid | GO:0033993 | 38 | 0.020 | |
| muscle cell development | GO:0055001 | 50 | 0.019 | |
| regulation of response to stress | GO:0080134 | 200 | 0.019 | |
| cellular amino acid metabolic process | GO:0006520 | 61 | 0.019 | |
| regulation of catalytic activity | GO:0050790 | 185 | 0.019 | |
| eye morphogenesis | GO:0048592 | 260 | 0.018 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 242 | 0.018 | |
| cell division | GO:0051301 | 248 | 0.018 | |
| negative regulation of cell cycle process | GO:0010948 | 109 | 0.018 | |
| cellular ketone metabolic process | GO:0042180 | 24 | 0.018 | |
| central nervous system development | GO:0007417 | 201 | 0.017 | |
| muscle cell differentiation | GO:0042692 | 103 | 0.017 | |
| regulation of heart contraction | GO:0008016 | 21 | 0.017 | |
| appendage morphogenesis | GO:0035107 | 397 | 0.017 | |
| regulation of blood circulation | GO:1903522 | 21 | 0.017 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 34 | 0.017 | |
| endomembrane system organization | GO:0010256 | 119 | 0.017 | |
| dorsal ventral axis specification | GO:0009950 | 66 | 0.016 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.016 | |
| muscle organ development | GO:0007517 | 127 | 0.016 | |
| defense response to other organism | GO:0098542 | 225 | 0.016 | |
| regulation of notch signaling pathway | GO:0008593 | 100 | 0.016 | |
| immune system process | GO:0002376 | 347 | 0.016 | |
| retina development in camera type eye | GO:0060041 | 4 | 0.016 | Zebrafish |
| regulation of phosphorylation | GO:0042325 | 147 | 0.016 | |
| apoptotic process | GO:0006915 | 159 | 0.016 | |
| regulation of mitotic cell cycle | GO:0007346 | 190 | 0.016 | |
| positive regulation of organelle organization | GO:0010638 | 65 | 0.016 | |
| positive regulation of multicellular organismal process | GO:0051240 | 143 | 0.016 | |
| protein acylation | GO:0043543 | 42 | 0.016 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 0 | 0.016 | |
| cellular macromolecular complex assembly | GO:0034622 | 153 | 0.015 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.015 | |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.015 | |
| heart contraction | GO:0060047 | 26 | 0.015 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 1 | 0.015 | |
| cell cycle phase transition | GO:0044770 | 140 | 0.014 | |
| tube morphogenesis | GO:0035239 | 191 | 0.014 | |
| regulation of chromatin modification | GO:1903308 | 28 | 0.014 | |
| regulation of cell cycle process | GO:0010564 | 181 | 0.014 | |
| sensory organ morphogenesis | GO:0090596 | 260 | 0.014 | |
| imaginal disc derived leg morphogenesis | GO:0007480 | 80 | 0.014 | |
| regulation of cell division | GO:0051302 | 72 | 0.014 | |
| tube development | GO:0035295 | 244 | 0.014 | |
| organonitrogen compound metabolic process | GO:1901564 | 318 | 0.013 | |
| cell fate determination | GO:0001709 | 91 | 0.013 | |
| organic substance transport | GO:0071702 | 257 | 0.013 | |
| imaginal disc derived wing morphogenesis | GO:0007476 | 337 | 0.013 | |
| morphogenesis of a polarized epithelium | GO:0001738 | 93 | 0.013 | |
| positive regulation of gene expression epigenetic | GO:0045815 | 16 | 0.013 | |
| stem cell proliferation | GO:0072089 | 88 | 0.013 | |
| respiratory system development | GO:0060541 | 213 | 0.013 | |
| positive regulation of protein modification process | GO:0031401 | 58 | 0.012 | |
| establishment of chromosome localization | GO:0051303 | 20 | 0.012 | |
| regulation of nuclear division | GO:0051783 | 58 | 0.012 | |
| proteolysis | GO:0006508 | 192 | 0.012 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.012 | |
| establishment of planar polarity | GO:0001736 | 87 | 0.012 | |
| response to organic cyclic compound | GO:0014070 | 89 | 0.012 | |
| protein complex assembly | GO:0006461 | 200 | 0.012 | |
| cellular response to lipopolysaccharide | GO:0071222 | 3 | 0.012 | |
| cell cycle comprising mitosis without cytokinesis | GO:0033301 | 25 | 0.012 | |
| cellular response to biotic stimulus | GO:0071216 | 4 | 0.012 | |
| growth | GO:0040007 | 359 | 0.012 | |
| cell cell signaling involved in cell fate commitment | GO:0045168 | 210 | 0.012 | |
| regulation of protein modification process | GO:0031399 | 112 | 0.011 | |
| regulation of embryonic development | GO:0045995 | 68 | 0.011 | |
| circulatory system process | GO:0003013 | 37 | 0.011 | |
| cell maturation | GO:0048469 | 144 | 0.011 | |
| actin filament based process | GO:0030029 | 220 | 0.011 | |
| positive regulation of cell proliferation | GO:0008284 | 47 | 0.011 | |
| positive regulation of catalytic activity | GO:0043085 | 118 | 0.011 | |
| negative regulation of cellular component organization | GO:0051129 | 108 | 0.011 | |
| metaphase plate congression | GO:0051310 | 19 | 0.011 | |
| methylation | GO:0032259 | 47 | 0.011 | |
| cell cycle checkpoint | GO:0000075 | 95 | 0.011 | |
| connective tissue development | GO:0061448 | 3 | 0.011 | |
| phagocytosis | GO:0006909 | 215 | 0.011 | |
| regionalization | GO:0003002 | 416 | 0.010 | |
| stem cell development | GO:0048864 | 79 | 0.010 | |
| regulation of dna replication | GO:0006275 | 13 | 0.010 | |
| leg disc morphogenesis | GO:0007478 | 80 | 0.010 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 78 | 0.010 | |
| biological adhesion | GO:0022610 | 138 | 0.010 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 3 | 0.010 | |
| regulation of phosphate metabolic process | GO:0019220 | 210 | 0.010 | |