Drosophila melanogaster

5 known processes

Mlc1 (Dmel_CG5596)

Myosin alkali light chain 1

(Aliases: mlc,Mlci,Dmel\CG5596,LC1,MLC-ALK,ELC,MlcI,mlc1,mlcl,FBgn0002772,mlc-alk,CG5596,Mlc-1,DmMLC1,MLC1)

Mlc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
striated muscle cell differentiationGO:0051146900.692
muscle cell differentiationGO:00426921030.505
muscle thin filament assemblyGO:007168950.242
muscle structure developmentGO:00610612240.191
larval developmentGO:00021641040.175
agingGO:00075681430.170
myotube differentiationGO:0014902460.160
striated muscle cell developmentGO:0055002500.144
actin filament organizationGO:00070151260.138
phosphorylationGO:00163102940.132
organophosphate metabolic processGO:00196371950.129
skeletal muscle adaptationGO:004350110.113
striated muscle myosin thick filament assemblyGO:007168830.108
cell divisionGO:00513012480.104
growthGO:00400073590.094
nucleoside triphosphate metabolic processGO:00091411200.090
muscle cell developmentGO:0055001500.086
ribonucleoside monophosphate catabolic processGO:0009158390.084
regulation of cellular component sizeGO:0032535980.083
actin filament based processGO:00300292200.083
Fly
myotube cell developmentGO:001490430.077
cellular component assembly involved in morphogenesisGO:00109271510.074
actin cytoskeleton organizationGO:00300362060.071
protein localization to organelleGO:0033365820.068
single organism intracellular transportGO:19025822070.067
nuclear transportGO:0051169720.067
ovipositionGO:0018991190.066
Worm
establishment of localization in cellGO:00516494020.064
multi multicellular organism processGO:00447061230.063
Worm
cytokinesisGO:0000910900.062
nucleoside triphosphate catabolic processGO:00091431080.062
purine nucleoside triphosphate catabolic processGO:00091461080.061
regulation of growthGO:00400082330.060
nucleocytoplasmic transportGO:0006913720.056
single organism nuclear importGO:1902593510.055
protein targeting to nucleusGO:0044744510.054
actomyosin structure organizationGO:0031032560.054
positive regulation of protein import into nucleusGO:0042307210.054
positive regulation of phosphate metabolic processGO:00459371390.052
glycerol 3 phosphate metabolic processGO:000607220.052
regulation of intracellular protein transportGO:0033157460.051
actin filament based movementGO:0030048260.050
Fly
cellular respirationGO:0045333260.050
vesicle mediated transportGO:00161923810.049
embryo development ending in birth or egg hatchingGO:00097921520.049
myofibril assemblyGO:0030239360.047
cellular protein complex assemblyGO:0043623710.046
chaeta developmentGO:0022416970.045
mesoderm developmentGO:0007498780.045
intracellular transportGO:00469072280.043
regulation of actin filament depolymerizationGO:003083430.043
anatomical structure homeostasisGO:0060249970.042
nucleotide metabolic processGO:00091171610.042
developmental growthGO:00485892800.041
positive regulation of growthGO:0045927750.040
regulation of cytoskeleton organizationGO:0051493890.040
centrosome organizationGO:00512971630.040
muscle tissue morphogenesisGO:006041520.039
cytoplasmic transportGO:00164821300.039
positive regulation of nucleoside metabolic processGO:0045979470.039
regulation of protein import into nucleusGO:0042306280.038
muscle organ developmentGO:00075171270.038
sarcomere organizationGO:0045214260.038
syncytium formation by plasma membrane fusionGO:0000768430.038
nucleobase containing compound catabolic processGO:00346551650.037
striated muscle tissue developmentGO:0014706270.036
glycolytic processGO:000609660.035
negative regulation of actin filament depolymerizationGO:003083520.035
cytoskeleton dependent cytokinesisGO:0061640810.034
extracellular matrix disassemblyGO:002261740.034
intracellular signal transductionGO:00355563000.034
aromatic compound catabolic processGO:00194391660.034
atp metabolic processGO:0046034490.033
embryonic morphogenesisGO:00485982060.033
ribonucleoside triphosphate catabolic processGO:00092031080.031
hematopoietic progenitor cell differentiationGO:000224410.031
establishment of protein localization to organelleGO:0072594620.031
cellular macromolecular complex assemblyGO:00346221530.031
regulation of transcription factor import into nucleusGO:0042990220.030
peptidyl threonine phosphorylationGO:001810720.030
ribose phosphate metabolic processGO:00196931450.029
protein targetingGO:0006605640.029
protein localization to nucleusGO:0034504550.029
muscle system processGO:0003012210.029
cellular protein modification processGO:00064644380.029
ribonucleoside monophosphate metabolic processGO:0009161510.028
regulation of establishment of protein localizationGO:0070201610.028
ribonucleoside triphosphate metabolic processGO:00091991190.028
positive regulation of nucleocytoplasmic transportGO:0046824240.028
development of primary sexual characteristicsGO:0045137500.027
regulation of actin filament polymerizationGO:0030833250.027
tissue morphogenesisGO:00487292970.027
regulation of catabolic processGO:00098941700.027
nuclear importGO:0051170510.027
protein depolymerizationGO:0051261310.027
camera type eye developmentGO:004301040.027
purine containing compound metabolic processGO:00725211550.027
regulation of anatomical structure sizeGO:00900661630.026
purine ribonucleoside triphosphate metabolic processGO:00092051190.026
posttranscriptional regulation of gene expressionGO:00106081450.026
organelle assemblyGO:00709251980.026
regulation of intracellular signal transductionGO:19025312360.025
protein import into nucleusGO:0006606510.025
cell motilityGO:00488702510.025
purine ribonucleotide metabolic processGO:00091501450.025
protein catabolic processGO:00301631010.025
protein transportGO:00150311550.024
nucleoside monophosphate metabolic processGO:0009123520.024
ribonucleotide catabolic processGO:00092611090.024
carbohydrate derivative catabolic processGO:19011361180.024
body morphogenesisGO:001017120.024
purine containing compound catabolic processGO:00725231120.023
ribonucleoside catabolic processGO:00424541120.023
small molecule metabolic processGO:00442813050.023
nucleoside phosphate metabolic processGO:00067531620.023
purine ribonucleoside triphosphate catabolic processGO:00092071080.023
purine nucleotide catabolic processGO:00061951090.023
positive regulation of atp catabolic processGO:190329130.022
purine nucleotide metabolic processGO:00061631460.022
glycosyl compound metabolic processGO:19016571270.022
regulation of cytoplasmic transportGO:1903649470.022
regulation of localizationGO:00328792750.022
cellular nitrogen compound catabolic processGO:00442701650.022
protein complex biogenesisGO:00702712010.022
stress fiber assemblyGO:004314960.022
purine ribonucleoside catabolic processGO:00461301120.021
regulation of phosphate metabolic processGO:00192202100.021
protein complex assemblyGO:00064612000.021
nucleobase containing small molecule metabolic processGO:00550861740.021
regulation of cell differentiationGO:00455953020.021
syncytium formationGO:0006949430.021
nucleoside monophosphate catabolic processGO:0009125390.021
carbohydrate derivative metabolic processGO:19011352170.021
positive regulation of purine nucleotide metabolic processGO:1900544550.020
multicellular organism growthGO:0035264460.020
muscle tissue developmentGO:0060537300.020
purine nucleoside monophosphate metabolic processGO:0009126500.020
nucleoside phosphate catabolic processGO:19012921100.020
immune responseGO:00069552460.020
mitotic cytokinesisGO:0000281500.020
protein polymerizationGO:0051258420.020
nadh metabolic processGO:000673410.020
localization of cellGO:00516742570.019
purine nucleoside monophosphate catabolic processGO:0009128380.019
cellular component disassemblyGO:0022411460.019
positive regulation of cell adhesionGO:0045785100.019
positive regulation of hydrolase activityGO:0051345780.019
cell migrationGO:00164772380.018
positive regulation of catalytic activityGO:00430851180.018
macromolecule catabolic processGO:00090571610.018
immune system processGO:00023763470.018
positive regulation of transcription factor import into nucleusGO:0042993190.018
nucleus localizationGO:0051647340.018
stem cell differentiationGO:00488631170.018
regulation of nucleocytoplasmic transportGO:0046822350.017
pharynx developmentGO:006046510.017
purine nucleoside metabolic processGO:00422781270.017
positive regulation of developmental processGO:00510941430.017
regulation of protein complex disassemblyGO:0043244290.017
nucleoside metabolic processGO:00091161270.017
skeletal muscle organ developmentGO:0060538480.017
positive regulation of catabolic processGO:00098961050.017
positive regulation of cellular catabolic processGO:0031331950.016
ribonucleotide metabolic processGO:00092591450.016
actin polymerization or depolymerizationGO:0008154310.016
positive regulation of nucleobase containing compound metabolic processGO:00459353320.016
actin filament cappingGO:005169320.016
central nervous system developmentGO:00074172010.016
nad metabolic processGO:001967410.016
regulation of actin filament lengthGO:0030832270.016
catabolic processGO:00090564090.016
regulation of actin polymerization or depolymerizationGO:0008064270.016
negative regulation of protein complex disassemblyGO:0043242230.015
actin mediated cell contractionGO:0070252210.015
regulation of phosphorus metabolic processGO:00511742100.015
positive regulation of phosphorus metabolic processGO:00105621390.015
purine ribonucleoside monophosphate metabolic processGO:0009167500.015
purine ribonucleotide catabolic processGO:00091541090.015
single organism catabolic processGO:00447122280.015
myosin filament assemblyGO:003103450.015
macromolecular complex assemblyGO:00650032560.015
heterocycle catabolic processGO:00467001660.014
response to oxygen containing compoundGO:19017002000.014
cell adhesionGO:00071551360.014
positive regulation of nucleotide catabolic processGO:0030813460.014
positive regulation of intracellular transportGO:0032388420.014
single organism cellular localizationGO:19025801800.014
skeletal muscle fiber developmentGO:004874130.014
glycosyl compound catabolic processGO:19016581120.014
regulation of cell morphogenesisGO:00226041630.014
regulation of developmental growthGO:00486381740.014
regulation of synapse structure and activityGO:00508031280.014
defense response to bacteriumGO:00427421780.014
negative regulation of cellular component organizationGO:00511291080.013
positive regulation of nfat protein import into nucleusGO:0051533160.013
purine nucleoside catabolic processGO:00061521120.013
mitotic nuclear divisionGO:00070672130.013
intracellular protein transportGO:00068861040.013
cellular catabolic processGO:00442483720.013
cell agingGO:000756920.013
atp catabolic processGO:0006200380.013
regulation of protein targetingGO:1903533290.013
cell recognitionGO:00080371020.013
purine ribonucleoside monophosphate catabolic processGO:0009169380.013
digestive tract developmentGO:00485651490.013
regulation of catalytic activityGO:00507901850.013
regulation of organelle organizationGO:00330431960.013
nfat protein import into nucleusGO:0051531160.013
negative regulation of protein polymerizationGO:003227270.013
regulation of protein transportGO:0051223570.012
organic cyclic compound catabolic processGO:19013611680.012
sex differentiationGO:0007548810.012
purine ribonucleoside metabolic processGO:00461281270.012
regulation of cell shapeGO:00083601130.012
generation of precursor metabolites and energyGO:0006091420.012
cardiac muscle cell differentiationGO:005500740.012
positive regulation of protein localization to nucleusGO:1900182210.012
nucleoside catabolic processGO:00091641120.012
positive regulation of stress fiber assemblyGO:005149630.012
endocytosisGO:00068973100.012
response to oxidative stressGO:0006979860.012
reproductive structure developmentGO:0048608740.012
microtubule polymerization or depolymerizationGO:0031109390.012
regulation of protein localization to nucleusGO:1900180290.012
positive regulation of nitrogen compound metabolic processGO:00511733540.012
regulation of protein localizationGO:0032880760.012
determination of adult lifespanGO:00083401370.011
ovulationGO:003072840.011
muscle adaptationGO:004350010.011
positive regulation of purine nucleotide catabolic processGO:0033123460.011
establishment of protein localizationGO:00451841630.011
regulation of purine nucleotide metabolic processGO:1900542620.011
somatic muscle developmentGO:0007525660.011
muscle contractionGO:0006936130.011
regulation of multicellular organism growthGO:0040014400.011
brain developmentGO:00074201200.011
positive regulation of intracellular protein transportGO:0090316300.011
phagocytosisGO:00069092150.010
neurological system processGO:00508773580.010
reproductive system developmentGO:0061458740.010
sensory organ morphogenesisGO:00905962600.010
regulation of purine nucleotide catabolic processGO:0033121480.010
regulation of molecular functionGO:00650092170.010
organophosphate catabolic processGO:00464341120.010

Mlc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscle tissue diseaseDOID:6600.149
cardiovascular system diseaseDOID:128700.149
musculoskeletal system diseaseDOID:1700.149
disease of anatomical entityDOID:700.149
cardiomyopathyDOID:005070000.149
heart diseaseDOID:11400.149
muscular diseaseDOID:008000000.149
myopathyDOID:42300.149
intrinsic cardiomyopathyDOID:006003600.055
dilated cardiomyopathyDOID:1293000.035