IMP: Integrative Multi-species Prediction

Drosophila melanogaster

9 known processes

CG9173 (Dmel_CG9173)

CG9173 gene product from transcript CG9173-RA

(Aliases: Dmel\CG9173)

FLYBASE: FBgn0035218
Entrez: 38165
UniProtKB: Q9W0F5

Process Predictions
Disease Predictions

CG9173 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.186
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.149
regulation of protein metabolic process	GO:0051246	256	0.137
positive regulation of transcription dna templated	GO:0045893	266	0.126
death	GO:0016265	284	0.116
positive regulation of cellular biosynthetic process	GO:0031328	316	0.114
regulation of cell cycle	GO:0051726	291	0.113
negative regulation of gene expression	GO:0010629	387	0.110
positive regulation of macromolecule metabolic process	GO:0010604	405	0.107
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.104
positive regulation of biosynthetic process	GO:0009891	316	0.103
negative regulation of cellular biosynthetic process	GO:0031327	277	0.093
negative regulation of cellular metabolic process	GO:0031324	382	0.078
negative regulation of biosynthetic process	GO:0009890	277	0.077
single organism behavior	GO:0044708	391	0.077
negative regulation of response to stimulus	GO:0048585	258	0.072
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.070
response to biotic stimulus	GO:0009607	294	0.062
posttranscriptional regulation of gene expression	GO:0010608	145	0.062
positive regulation of rna metabolic process	GO:0051254	271	0.061
regulation of translation	GO:0006417	56	0.060
regulation of cellular protein metabolic process	GO:0032268	243	0.060
regulation of cell differentiation	GO:0045595	302	0.059
positive regulation of gene expression	GO:0010628	290	0.057
cell death	GO:0008219	279	0.057
translation	GO:0006412	69	0.053
defense response to bacterium	GO:0042742	178	0.053
negative regulation of translation	GO:0017148	28	0.048
developmental growth	GO:0048589	280	0.048
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.048
regulation of cell cycle process	GO:0010564	181	0.048
positive regulation of rna biosynthetic process	GO:1902680	266	0.045
cellular protein modification process	GO:0006464	438	0.045
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.045
central nervous system development	GO:0007417	201	0.044
protein localization	GO:0008104	284	0.044
regulation of mitotic cell cycle	GO:0007346	190	0.043
lateral inhibition	GO:0046331	206	0.041
small molecule metabolic process	GO:0044281	305	0.041
positive regulation of molecular function	GO:0044093	136	0.041
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.041
response to other organism	GO:0051707	293	0.040
immune system process	GO:0002376	347	0.040
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.038
growth	GO:0040007	359	0.038
protein modification process	GO:0036211	438	0.038
defense response to other organism	GO:0098542	225	0.037
stem cell maintenance	GO:0019827	67	0.037
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.037
immune response	GO:0006955	246	0.036
dna metabolic process	GO:0006259	227	0.035
regulation of gene expression epigenetic	GO:0040029	128	0.035
macromolecular complex assembly	GO:0065003	256	0.035
organic substance catabolic process	GO:1901575	308	0.034
mitotic spindle organization	GO:0007052	220	0.033
response to abiotic stimulus	GO:0009628	341	0.032
dephosphorylation	GO:0016311	51	0.031
phosphorylation	GO:0016310	294	0.031
eye morphogenesis	GO:0048592	260	0.031
transcription from rna polymerase ii promoter	GO:0006366	368	0.031
regulation of molecular function	GO:0065009	217	0.031
imaginal disc derived wing morphogenesis	GO:0007476	337	0.030
organic substance transport	GO:0071702	257	0.030
defense response	GO:0006952	300	0.030
brain development	GO:0007420	120	0.030
negative regulation of rna biosynthetic process	GO:1902679	240	0.030
positive regulation of cellular protein metabolic process	GO:0032270	118	0.030
mitotic nuclear division	GO:0007067	213	0.029
catabolic process	GO:0009056	409	0.029
establishment or maintenance of cell polarity	GO:0007163	167	0.028
spindle organization	GO:0007051	253	0.026
compound eye development	GO:0048749	307	0.026
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.026
establishment of localization in cell	GO:0051649	402	0.025
developmental programmed cell death	GO:0010623	138	0.025
positive regulation of response to stimulus	GO:0048584	323	0.025
programmed cell death	GO:0012501	257	0.025
negative regulation of rna metabolic process	GO:0051253	251	0.025
regulation of organelle organization	GO:0033043	196	0.024
response to external biotic stimulus	GO:0043207	293	0.024
regulation of catalytic activity	GO:0050790	185	0.023
cellular response to chemical stimulus	GO:0070887	199	0.023
locomotory behavior	GO:0007626	176	0.023
embryonic development via the syncytial blastoderm	GO:0001700	148	0.023
morphogenesis of embryonic epithelium	GO:0016331	94	0.023
regulation of immune system process	GO:0002682	176	0.023
cuticle development	GO:0042335	86	0.022
olfactory behavior	GO:0042048	97	0.022
salivary gland morphogenesis	GO:0007435	145	0.022
positive regulation of cell communication	GO:0010647	250	0.022
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.022
signal transduction by phosphorylation	GO:0023014	107	0.022
ras protein signal transduction	GO:0007265	88	0.022
dorsal closure	GO:0007391	79	0.022
compound eye morphogenesis	GO:0001745	249	0.022
regulation of microtubule based process	GO:0032886	49	0.022
spermatid development	GO:0007286	98	0.021
humoral immune response	GO:0006959	117	0.021
epithelial cell differentiation	GO:0030855	322	0.021
photoreceptor cell differentiation	GO:0046530	170	0.021
intracellular protein transport	GO:0006886	104	0.021
exocrine system development	GO:0035272	162	0.021
mushroom body development	GO:0016319	70	0.021
embryonic morphogenesis	GO:0048598	206	0.021
negative regulation of cell communication	GO:0010648	223	0.021
cytoplasmic translation	GO:0002181	0	0.020
larval development	GO:0002164	104	0.020
gene silencing	GO:0016458	138	0.020
positive regulation of signaling	GO:0023056	243	0.020
antimicrobial humoral response	GO:0019730	99	0.019
nuclear division	GO:0000280	332	0.019
cytoplasmic transport	GO:0016482	130	0.019
cellular response to dna damage stimulus	GO:0006974	223	0.019
centrosome duplication	GO:0051298	121	0.019
negative regulation of protein metabolic process	GO:0051248	85	0.019
defense response to gram negative bacterium	GO:0050829	94	0.019
positive regulation of phosphorylation	GO:0042327	87	0.018
intracellular signal transduction	GO:0035556	300	0.018
positive regulation of protein metabolic process	GO:0051247	128	0.018
positive regulation of signal transduction	GO:0009967	223	0.018
nuclear transport	GO:0051169	72	0.018
small gtpase mediated signal transduction	GO:0007264	88	0.018
tube development	GO:0035295	244	0.017
chemosensory behavior	GO:0007635	106	0.017
regulation of immune response	GO:0050776	118	0.017
positive regulation of developmental process	GO:0051094	143	0.017
cellular macromolecular complex assembly	GO:0034622	153	0.017
cell division	GO:0051301	248	0.017
endocytosis	GO:0006897	310	0.017
negative regulation of cell cycle process	GO:0010948	109	0.017
chromatin silencing	GO:0006342	76	0.017
negative regulation of transcription dna templated	GO:0045892	237	0.017
positive regulation of multicellular organismal process	GO:0051240	143	0.017
establishment of organelle localization	GO:0051656	122	0.017
regulation of organ morphogenesis	GO:2000027	78	0.016
regulation of cellular component biogenesis	GO:0044087	201	0.016
cognition	GO:0050890	141	0.016
post embryonic appendage morphogenesis	GO:0035120	385	0.016
r7 cell differentiation	GO:0045466	43	0.016
nucleocytoplasmic transport	GO:0006913	72	0.016
organelle localization	GO:0051640	148	0.016
microtubule organizing center organization	GO:0031023	168	0.016
stem cell development	GO:0048864	79	0.016
negative regulation of developmental process	GO:0051093	201	0.016
cell proliferation	GO:0008283	299	0.016
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.015
regulation of phosphorylation	GO:0042325	147	0.015
endomembrane system organization	GO:0010256	119	0.015
regulation of phosphorus metabolic process	GO:0051174	210	0.015
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.015
regulation of mapk cascade	GO:0043408	92	0.015
negative regulation of cellular protein metabolic process	GO:0032269	85	0.015
morphogenesis of an epithelium	GO:0002009	276	0.015
organelle fission	GO:0048285	340	0.015
regulation of response to biotic stimulus	GO:0002831	63	0.015
segmentation	GO:0035282	207	0.015
cellular catabolic process	GO:0044248	372	0.014
cellular component disassembly	GO:0022411	46	0.014
eggshell chorion assembly	GO:0007306	66	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.014
dna integrity checkpoint	GO:0031570	81	0.014
positive regulation of phosphorus metabolic process	GO:0010562	139	0.014
protein targeting to nucleus	GO:0044744	51	0.014
single organism cellular localization	GO:1902580	180	0.014
negative regulation of gene expression epigenetic	GO:0045814	77	0.014
protein complex biogenesis	GO:0070271	201	0.014
regulation of intracellular signal transduction	GO:1902531	236	0.014
embryo development ending in birth or egg hatching	GO:0009792	152	0.014
positive regulation of cellular component organization	GO:0051130	156	0.014
learning or memory	GO:0007611	141	0.014
protein import into nucleus	GO:0006606	51	0.014
centrosome cycle	GO:0007098	137	0.013
centrosome organization	GO:0051297	163	0.013
nuclear import	GO:0051170	51	0.013
tissue morphogenesis	GO:0048729	297	0.013
forebrain development	GO:0030900	2	0.013
mapk cascade	GO:0000165	107	0.013
spermatogenesis	GO:0007283	200	0.013
regulation of localization	GO:0032879	275	0.013
cellular protein localization	GO:0034613	160	0.013
single organism intracellular transport	GO:1902582	207	0.013
body morphogenesis	GO:0010171	2	0.013
negative regulation of mitotic cell cycle	GO:0045930	109	0.013
regulation of response to stress	GO:0080134	200	0.013
negative regulation of signal transduction	GO:0009968	206	0.013
spermatid differentiation	GO:0048515	114	0.013
camera type eye development	GO:0043010	4	0.013
positive regulation of developmental growth	GO:0048639	62	0.013
peptidyl amino acid modification	GO:0018193	105	0.013
regulation of innate immune response	GO:0045088	71	0.013
membrane organization	GO:0061024	112	0.013
innate immune response	GO:0045087	144	0.013
establishment of protein localization	GO:0045184	163	0.013
negative regulation of signaling	GO:0023057	219	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.012
regulation of multicellular organismal development	GO:2000026	414	0.012
regulation of protein import into nucleus	GO:0042306	28	0.012
regulation of cell death	GO:0010941	173	0.012
regulation of apoptotic process	GO:0042981	130	0.012
regulation of growth	GO:0040008	233	0.012
appendage development	GO:0048736	401	0.012
regulation of cellular ketone metabolic process	GO:0010565	3	0.012
telencephalon development	GO:0021537	2	0.012
response to oxygen containing compound	GO:1901700	200	0.012
regulation of protein modification process	GO:0031399	112	0.012
axon development	GO:0061564	297	0.012
imaginal disc derived appendage development	GO:0048737	399	0.012
taxis	GO:0042330	304	0.012
protein transport	GO:0015031	155	0.012
adult locomotory behavior	GO:0008344	76	0.012
mitotic cell cycle phase transition	GO:0044772	138	0.012
stem cell differentiation	GO:0048863	117	0.012
single organism biosynthetic process	GO:0044711	206	0.012
compound eye photoreceptor cell differentiation	GO:0001751	140	0.012
sex differentiation	GO:0007548	81	0.011
gland morphogenesis	GO:0022612	145	0.011
single organism catabolic process	GO:0044712	228	0.011
cellular response to organic substance	GO:0071310	132	0.011
protein complex assembly	GO:0006461	200	0.011
positive regulation of organelle organization	GO:0010638	65	0.011
eye development	GO:0001654	323	0.011
neuron projection guidance	GO:0097485	241	0.011
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.011
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.011
salivary gland development	GO:0007431	162	0.011
embryonic pattern specification	GO:0009880	174	0.011
cell cycle phase transition	GO:0044770	140	0.011
regulation of ras protein signal transduction	GO:0046578	93	0.011
notch signaling pathway	GO:0007219	120	0.011
protein phosphorylation	GO:0006468	169	0.011
developmental maturation	GO:0021700	172	0.011
regulation of developmental growth	GO:0048638	174	0.011
vesicle mediated transport	GO:0016192	381	0.011
retina development in camera type eye	GO:0060041	4	0.011
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.011
organic cyclic compound catabolic process	GO:1901361	168	0.011
protein dephosphorylation	GO:0006470	27	0.010
gland development	GO:0048732	191	0.010
proteolysis	GO:0006508	192	0.010
positive regulation of cellular component biogenesis	GO:0044089	80	0.010
single organism nuclear import	GO:1902593	51	0.010
dna damage checkpoint	GO:0000077	78	0.010
axon guidance	GO:0007411	233	0.010
regulation of programmed cell death	GO:0043067	152	0.010
regulation of cell cycle phase transition	GO:1901987	130	0.010
positive regulation of growth	GO:0045927	75	0.010
carboxylic acid metabolic process	GO:0019752	92	0.010
regulation of intracellular protein transport	GO:0033157	46	0.010
nitrogen compound transport	GO:0071705	85	0.010
sensory organ morphogenesis	GO:0090596	260	0.010

CG9173 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.024
nervous system disease	DOID:863	0.012
kidney disease	DOID:557	0.010
urinary system disease	DOID:18	0.010

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