Drosophila melanogaster

157 known processes

smo (Dmel_CG11561)

smoothened

(Aliases: SMO,Smo,dSmo,Dmel\CG11561,CG11561)

smo biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cell communicationGO:00106482230.978
forebrain developmentGO:003090020.975
Zebrafish Mouse
tube morphogenesisGO:00352391910.973
Zebrafish Mouse
post embryonic appendage morphogenesisGO:00351203850.972
epithelial cell differentiationGO:00308553220.967
negative regulation of wnt signaling pathwayGO:0030178280.954
wing disc morphogenesisGO:00074723440.954
gastrulationGO:0007369700.954
appendage morphogenesisGO:00351073970.953
Zebrafish
cellular protein modification processGO:00064644380.937
ameboidal type cell migrationGO:00016671510.916
Mouse
meiotic cell cycle processGO:19030461320.907
imaginal disc derived wing morphogenesisGO:00074763370.900
negative regulation of response to stimulusGO:00485852580.887
negative regulation of signal transductionGO:00099682060.826
nuclear divisionGO:00002803320.825
negative regulation of developmental growthGO:0048640640.823
negative regulation of cellular metabolic processGO:00313243820.820
Mouse
regulation of ras gtpase activityGO:0032318380.817
convergent extensionGO:006002620.802
regulation of developmental growthGO:00486381740.764
heart developmentGO:0007507820.747
Zebrafish Mouse
open tracheal system developmentGO:00074242040.741
respiratory system developmentGO:00605412130.737
muscle structure developmentGO:00610612240.719
Zebrafish Mouse
negative regulation of multicellular organismal processGO:00512411420.714
Mouse
digestive tract developmentGO:00485651490.711
Zebrafish Mouse
head developmentGO:00603221350.711
Zebrafish Mouse
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.694
programmed cell deathGO:00125012570.690
meiotic cell cycleGO:00513211710.685
cell motilityGO:00488702510.679
Zebrafish Mouse
morphogenesis of a branching structureGO:0001763450.676
Mouse
columnar cuboidal epithelial cell developmentGO:00020662490.663
muscle cell differentiationGO:00426921030.663
Zebrafish Mouse
negative regulation of cell differentiationGO:00455961430.660
endodermal cell fate commitmentGO:000171130.648
tissue migrationGO:00901301550.642
digestive system developmentGO:00551231490.626
Zebrafish Mouse
regionalizationGO:00030024160.622
regulation of catabolic processGO:00098941700.619
localization of cellGO:00516742570.612
Zebrafish Mouse
meiotic nuclear divisionGO:00071261510.610
endocytosisGO:00068973100.607
peripheral nervous system developmentGO:0007422520.601
proteolysisGO:00065081920.592
intracellular transportGO:00469072280.591
Mouse
regulation of neurogenesisGO:00507671580.589
Mouse
regulation of cell cycle g1 s phase transitionGO:1902806230.588
columnar cuboidal epithelial cell differentiationGO:00020652560.585
regulation of multicellular organismal developmentGO:20000264140.576
Mouse
protein localization to nucleusGO:0034504550.573
Mouse
epithelial tube morphogenesisGO:0060562880.571
Zebrafish Mouse
regulation of cell proliferationGO:00421271630.559
Mouse
negative regulation of developmental processGO:00510932010.556
sulfur compound metabolic processGO:0006790590.540
protein modification processGO:00362114380.533
retinal ganglion cell axon guidanceGO:0031290120.531
Zebrafish
muscle tissue developmentGO:0060537300.519
Zebrafish Mouse
regulation of cellular catabolic processGO:00313291570.519
appendage developmentGO:00487364010.518
Zebrafish
imaginal disc pattern formationGO:0007447910.510
ovarian follicle cell migrationGO:00072971210.493
imaginal disc derived appendage morphogenesisGO:00351143950.489
central nervous system developmentGO:00074172010.486
Zebrafish Mouse Rat
cell divisionGO:00513012480.482
ubiquitin dependent protein catabolic processGO:0006511780.480
regulation of cytoskeleton organizationGO:0051493890.471
muscle organ developmentGO:00075171270.460
Zebrafish Mouse
gliogenesisGO:0042063800.458
Zebrafish Mouse
sensory organ morphogenesisGO:00905962600.456
regulation of protein catabolic processGO:0042176550.446
cardiovascular system developmentGO:0072358820.443
Zebrafish Mouse
protein catabolic processGO:00301631010.441
skeletal muscle organ developmentGO:0060538480.440
Zebrafish Mouse
ovarian follicle cell developmentGO:00307072480.438
homeostatic processGO:00425921990.437
Mouse
positive regulation of developmental processGO:00510941430.430
Mouse
gland developmentGO:00487321910.429
Zebrafish Mouse
negative regulation of signalingGO:00230572190.423
positive regulation of nitrogen compound metabolic processGO:00511733540.416
Mouse
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.415
Mouse
striated muscle tissue developmentGO:0014706270.409
Zebrafish Mouse
multi organism behaviorGO:00517051750.403
brain developmentGO:00074201200.390
Zebrafish Mouse
eye developmentGO:00016543230.385
organelle fissionGO:00482853400.382
epithelial cell developmentGO:00020642740.376
regulation of mitotic cell cycleGO:00073461900.373
regulation of immune system processGO:00026821760.370
positive regulation of molecular functionGO:00440931360.364
Mouse
regulation of muscle organ developmentGO:0048634130.363
posttranscriptional regulation of gene expressionGO:00106081450.362
Mouse
immune system processGO:00023763470.359
cellular protein catabolic processGO:0044257830.358
embryonic morphogenesisGO:00485982060.351
Zebrafish Mouse
taxisGO:00423303040.348
Zebrafish Rat
intracellular signal transductionGO:00355563000.346
Mouse
actin filament bundle organizationGO:0061572280.341
positive regulation of pathway restricted smad protein phosphorylationGO:001086210.340
epithelium migrationGO:00901321480.332
imaginal disc derived appendage developmentGO:00487373990.328
regulation of intracellular signal transductionGO:19025312360.327
regulation of pathway restricted smad protein phosphorylationGO:006039310.326
multicellular organismal reproductive behaviorGO:00330571100.322
single organism intracellular transportGO:19025822070.319
Mouse
regulation of wnt signaling pathwayGO:0030111680.314
regulation of microtubule based processGO:0032886490.314
regulation of epithelial cell proliferationGO:005067840.311
Mouse
cytoplasmic transportGO:00164821300.310
Mouse
tissue morphogenesisGO:00487292970.310
Zebrafish Mouse
negative regulation of cellular biosynthetic processGO:00313272770.308
Mouse
proteolysis involved in cellular protein catabolic processGO:0051603830.303
neuroblast proliferationGO:0007405740.300
Mouse
regulation of growthGO:00400082330.298
modification dependent macromolecule catabolic processGO:0043632790.294
morphogenesis of an epitheliumGO:00020092760.294
Zebrafish Mouse
lipid metabolic processGO:00066291210.290
imaginal disc derived wing vein morphogenesisGO:0008586440.283
mesenchymal cell differentiationGO:004876210.281
Zebrafish Mouse
developmental growthGO:00485892800.279
Mouse Rat
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.272
regulation of phosphorus metabolic processGO:00511742100.267
compound eye photoreceptor cell differentiationGO:00017511400.264
epithelial cell migrationGO:00106311480.264
regulation of nervous system developmentGO:00519602480.259
Mouse
striated muscle cell differentiationGO:0051146900.252
Zebrafish Mouse
regulation of protein metabolic processGO:00512462560.249
organic acid metabolic processGO:00060821030.247
camera type eye developmentGO:004301040.244
Zebrafish
axon developmentGO:00615642970.232
Zebrafish Rat
wing disc pattern formationGO:0035222660.231
cell migration involved in gastrulationGO:004207490.231
gtp metabolic processGO:0046039720.231
positive regulation of gtp catabolic processGO:0033126430.230
deathGO:00162652840.229
positive regulation of catalytic activityGO:00430851180.227
epidermal cell differentiationGO:0009913510.226
regulation of synaptic growth at neuromuscular junctionGO:0008582890.223
protein modification by small protein conjugation or removalGO:00706471060.223
imaginal disc derived wing vein specificationGO:0007474480.222
growthGO:00400073590.219
Mouse Rat
camera type eye morphogenesisGO:004859320.216
guanosine containing compound catabolic processGO:1901069740.216
proteoglycan biosynthetic processGO:0030166100.216
response to external biotic stimulusGO:00432072930.206
ectodermal placode formationGO:006078840.205
regulation of anatomical structure morphogenesisGO:00226032420.198
Mouse
positive regulation of cellular component biogenesisGO:0044089800.196
multi multicellular organism processGO:00447061230.195
synaptic growth at neuromuscular junctionGO:00511241190.194
positive regulation of macromolecule metabolic processGO:00106044050.192
Mouse
organ growthGO:0035265560.192
neuromuscular junction developmentGO:00075281490.185
apoptotic processGO:00069151590.183
protein targetingGO:0006605640.181
Mouse
regulation of cellular protein catabolic processGO:1903362440.181
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.180
negative regulation of nervous system developmentGO:0051961920.180
organic substance transportGO:00717022570.175
Mouse
spindle organizationGO:00070512530.170
cell fate commitment involved in formation of primary germ layerGO:0060795100.170
stem cell differentiationGO:00488631170.169
positive regulation of gtpase activityGO:0043547430.167
circulatory system developmentGO:0072359820.167
Zebrafish Mouse
axis specificationGO:00097981670.163
leg disc developmentGO:0035218920.163
imaginal disc derived leg morphogenesisGO:0007480800.159
positive regulation of protein metabolic processGO:00512471280.157
epithelial cell proliferationGO:0050673150.156
Mouse
actin filament based processGO:00300292200.156
Zebrafish
cell proliferationGO:00082832990.155
Mouse Rat
mitotic nuclear divisionGO:00070672130.155
regulation of smoothened signaling pathwayGO:0008589280.154
Zebrafish Mouse
oxoacid metabolic processGO:00434361030.152
glial cell differentiationGO:0010001350.151
Zebrafish Mouse
response to woundingGO:0009611940.149
Rat
vesicle mediated transportGO:00161923810.146
dorsal ventral pattern formationGO:00099531330.145
Zebrafish Mouse
positive regulation of developmental growthGO:0048639620.143
nucleocytoplasmic transportGO:0006913720.143
Mouse
heart morphogenesisGO:0003007320.143
Zebrafish Mouse
cell migrationGO:00164772380.140
Zebrafish Mouse
skin developmentGO:0043588650.140
Mouse
regulation of cell substrate adhesionGO:001081020.137
positive regulation of nucleoside metabolic processGO:0045979470.137
tube developmentGO:00352952440.136
Zebrafish Mouse
retina development in camera type eyeGO:006004140.135
Zebrafish
mesoderm formationGO:0001707210.134
negative regulation of epithelial cell proliferationGO:005068040.133
limb morphogenesisGO:003510810.133
morphogenesis of a branching epitheliumGO:0061138450.133
Mouse
positive regulation of cellular biosynthetic processGO:00313283160.133
Mouse
positive regulation of signalingGO:00230562430.132
Zebrafish Mouse
establishment of localization in cellGO:00516494020.131
Mouse
negative regulation of biosynthetic processGO:00098902770.129
Mouse
regulation of organ morphogenesisGO:2000027780.127
Mouse
response to other organismGO:00517072930.126
reproductive behaviorGO:00190981220.124
determination of dorsal ventral asymmetryGO:004826230.124
proteasomal protein catabolic processGO:0010498590.123
modification dependent protein catabolic processGO:0019941780.122
negative regulation of neurogenesisGO:0050768530.122
spermatid differentiationGO:00485151140.120
regulation of cellular protein metabolic processGO:00322682430.120
positive regulation of cellular protein metabolic processGO:00322701180.118
axonogenesisGO:00074092900.118
Zebrafish Rat
extracellular structure organizationGO:0043062460.117
negative regulation of macromolecule biosynthetic processGO:00105582700.115
Mouse
heparan sulfate proteoglycan metabolic processGO:0030201100.114
regulation of cell cycle phase transitionGO:19019871300.114
blastoderm segmentationGO:00073501590.113
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.112
single organismal cell cell adhesionGO:0016337450.111
small gtpase mediated signal transductionGO:0007264880.111
positive regulation of ras gtpase activityGO:0032320360.110
regulation of protein serine threonine kinase activityGO:0071900250.109
positive regulation of phosphorus metabolic processGO:00105621390.108
somatic stem cell maintenanceGO:0035019140.107
negative regulation of growthGO:0045926840.106
enzyme linked receptor protein signaling pathwayGO:00071671790.106
cell junction assemblyGO:0034329420.105
hematopoietic or lymphoid organ developmentGO:0048534570.104
formation of primary germ layerGO:0001704240.103
regulation of glial cell differentiationGO:004568510.101
gtp catabolic processGO:0006184720.100
cell elongation involved in imaginal disc derived wing morphogenesisGO:009025450.099
cell fate specificationGO:0001708710.099
Zebrafish Mouse
digestive tract morphogenesisGO:00485461270.098
Zebrafish
cell adhesionGO:00071551360.097
regulation of nucleoside metabolic processGO:0009118500.097
positive regulation of signal transductionGO:00099672230.096
Zebrafish Mouse
multi organism reproductive behaviorGO:00447051210.096
imaginal disc growthGO:0007446370.094
cellular macromolecule catabolic processGO:00442651360.093
response to biotic stimulusGO:00096072940.093
Human
negative regulation of nucleic acid templated transcriptionGO:19035072400.092
Mouse
female meiotic divisionGO:0007143700.092
sensory organ precursor cell divisionGO:0045035100.091
single organism biosynthetic processGO:00447112060.091
negative regulation of cellular protein metabolic processGO:0032269850.090
protein import into nucleusGO:0006606510.090
Mouse
regulation of proteolysisGO:0030162870.089
neuron projection guidanceGO:00974852410.089
Zebrafish Rat
positive regulation of mitotic cell cycleGO:0045931340.088
positive regulation of ribosome biogenesisGO:009007030.087
convergent extension involved in gastrulationGO:006002720.087
catabolic processGO:00090564090.086
cellular protein localizationGO:00346131600.086
embryonic foregut morphogenesisGO:004861730.085
organic substance catabolic processGO:19015753080.084
cation homeostasisGO:0055080510.083
endodermal cell differentiationGO:003598730.082
regulation of microtubule cytoskeleton organizationGO:0070507410.082
positive regulation of response to stimulusGO:00485843230.082
Zebrafish Mouse
membrane protein ectodomain proteolysisGO:000650950.082
protein importGO:0017038550.082
Mouse
single organism nuclear importGO:1902593510.081
Mouse
wnt signaling pathwayGO:0016055980.080
stem cell maintenanceGO:0019827670.080
protein localizationGO:00081042840.078
regulation of ras protein signal transductionGO:0046578930.078
notch signaling pathwayGO:00072191200.078
cellular catabolic processGO:00442483720.078
specification of symmetryGO:0009799130.078
Zebrafish Mouse
germ cell migrationGO:0008354430.077
canonical wnt signaling pathway involved in heart developmentGO:006131630.077
regulation of g1 s transition of mitotic cell cycleGO:2000045230.076
skeletal muscle tissue developmentGO:0007519130.076
Zebrafish Mouse
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.076
hemopoiesisGO:0030097460.074
cellular hormone metabolic processGO:0034754230.074
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.073
actin cytoskeleton organizationGO:00300362060.072
Zebrafish
regulation of catalytic activityGO:00507901850.072
positive regulation of phosphate metabolic processGO:00459371390.070
negative regulation of intracellular signal transductionGO:1902532570.070
epidermis developmentGO:0008544650.070
Mouse
neuron recognitionGO:00080381010.069
regulation of dna metabolic processGO:0051052340.069
regulation of cell differentiationGO:00455953020.069
determination of ventral identityGO:004826410.069
regulation of organelle organizationGO:00330431960.069
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574350.069
regulation of map kinase activityGO:0043405170.068
cellular chemical homeostasisGO:0055082400.068
positive regulation of catabolic processGO:00098961050.068
adherens junction organizationGO:0034332270.067
axon guidanceGO:00074112330.067
Zebrafish Rat
regulation of tube architecture open tracheal systemGO:0035152680.066
macromolecule catabolic processGO:00090571610.066
chromosome segregationGO:00070591570.066
ribonucleoside triphosphate metabolic processGO:00091991190.066
regulation of phosphate metabolic processGO:00192202100.066
eye antennal disc developmentGO:0035214600.066
positive regulation of cell adhesionGO:0045785100.066
neural precursor cell proliferationGO:0061351750.064
Mouse
positive regulation of rna biosynthetic processGO:19026802660.063
Mouse
cell fate determinationGO:0001709910.063
biological adhesionGO:00226101380.063
eye morphogenesisGO:00485922600.063
negative regulation of catabolic processGO:0009895360.062
positive regulation of cell communicationGO:00106472500.061
Zebrafish Mouse
protein targeting to nucleusGO:0044744510.061
Mouse
guanosine containing compound metabolic processGO:1901068740.061
imaginal disc derived wing hair organizationGO:0035317450.061
negative regulation of protein metabolic processGO:0051248850.061
positive regulation of nucleic acid templated transcriptionGO:19035082660.061
Mouse
enteroendocrine cell differentiationGO:003588310.060
Mouse
sex determinationGO:0007530180.059
carbohydrate derivative biosynthetic processGO:1901137850.057
regulation of defense responseGO:00313471020.057
regulation of synapse structure and activityGO:00508031280.056
negative regulation of rna metabolic processGO:00512532510.055
Mouse
stem cell divisionGO:0017145690.054
smoothened signaling pathway involved in ventral spinal cord patterningGO:002191000.054
Mouse
regulation of proteasomal protein catabolic processGO:0061136390.053
i kappab phosphorylationGO:000725230.053
negative regulation of nucleotide metabolic processGO:004598040.053
mushroom body developmentGO:0016319700.053
protein palmitoylationGO:001834520.052
hindbrain developmentGO:003090220.051
Zebrafish Mouse
amine metabolic processGO:0009308120.051
dna integrationGO:001507410.051
limb developmentGO:006017310.051
compound eye developmentGO:00487493070.051
regulation of sister chromatid cohesionGO:000706320.050
salivary gland developmentGO:00074311620.050
neurological system processGO:00508773580.049
protein complex biogenesisGO:00702712010.049
protein localization to organelleGO:0033365820.049
Mouse
regulation of gliogenesisGO:0014013110.048
cellular homeostasisGO:0019725800.048
anterior posterior pattern specificationGO:00099521360.048
Zebrafish Mouse
positive regulation of multicellular organism growthGO:0040018210.047
regulation of rho protein signal transductionGO:0035023200.046
chemical homeostasisGO:0048878920.046
mitotic sister chromatid segregationGO:0000070870.046
segmentationGO:00352822070.045
spinal cord dorsal ventral patterningGO:002151310.045
Mouse
single organism carbohydrate metabolic processGO:0044723720.045
regulation of immune responseGO:00507761180.045
compound eye morphogenesisGO:00017452490.045
glycoprotein biosynthetic processGO:0009101410.044
dorsal closure leading edge cell differentiationGO:004666320.044
wnt signaling pathway involved in heart developmentGO:000330630.044
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.043
proteoglycan metabolic processGO:0006029100.043
protein modification by small protein conjugationGO:0032446790.043
germarium derived female germ line cyst formationGO:0030727420.043
chemotaxisGO:00069352490.043
Zebrafish Rat
branching involved in open tracheal system developmentGO:0060446450.042
heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic processGO:001501450.042
carbohydrate metabolic processGO:0005975820.042
positive regulation of transcription dna templatedGO:00458932660.042
Mouse
metal ion homeostasisGO:0055065440.042
negative regulation of cell cycle g1 s phase transitionGO:1902807130.041
positive regulation of nucleotide metabolic processGO:0045981550.041
positive regulation of cellular catabolic processGO:0031331950.041
positive regulation of rho gtpase activityGO:0032321190.041
associative learningGO:0008306650.041
protein ubiquitinationGO:0016567700.041
maintenance of protein location in cellGO:0032507260.041
oocyte morphogenesisGO:004860130.041
establishment or maintenance of cell polarityGO:00071631670.040
regulation of neuron differentiationGO:00456641030.040
cellular lipid metabolic processGO:0044255830.040
positive regulation of protein catabolic processGO:0045732340.040
regulation of gtpase activityGO:0043087440.039
endoderm formationGO:000170630.039
cell junction organizationGO:0034330570.038
synapse organizationGO:00508081960.038
single organism cellular localizationGO:19025801800.038
regulation of synapse organizationGO:00508071100.037
rho protein signal transductionGO:0007266140.037
regulation of organ growthGO:0046620420.037
regulation of cell cycleGO:00517262910.037
transcription from rna polymerase ii promoterGO:00063663680.037
Mouse
cellular macromolecule localizationGO:00707272200.037
small molecule metabolic processGO:00442813050.036
regulation of cell morphogenesis involved in differentiationGO:0010769610.036
negative regulation of transcription dna templatedGO:00458922370.036
Mouse
telencephalon developmentGO:002153720.036
Zebrafish Mouse
regulation of imaginal disc growthGO:0045570260.036
phagocytosisGO:00069092150.036
ribonucleoside catabolic processGO:00424541120.035
retina morphogenesis in camera type eyeGO:006004220.035
smoothened signaling pathwayGO:0007224490.035
regulation of gtp catabolic processGO:0033124440.034
positive regulation of purine nucleotide catabolic processGO:0033123460.034
regulation of mapk cascadeGO:0043408920.034
unidimensional cell growthGO:0009826150.034
ras protein signal transductionGO:0007265880.034
defense response to gram negative bacteriumGO:0050829940.034
maintenance of location in cellGO:0051651280.034
germ line cyst formationGO:0048134440.034
positive regulation of nervous system developmentGO:0051962690.034
Mouse
regulation of mitosisGO:0007088560.033
negative regulation of cellular catabolic processGO:0031330340.033
regulation of gene expression epigeneticGO:00400291280.033
regulation of intracellular protein transportGO:0033157460.033
Mouse
regulation of synapse assemblyGO:0051963940.033
response to bacteriumGO:00096171980.033
spinal cord developmentGO:002151010.033
Zebrafish Mouse
regulation of molecular functionGO:00650092170.033
Mouse
carbohydrate biosynthetic processGO:0016051170.032
regulation of apoptotic processGO:00429811300.032
embryonic pattern specificationGO:00098801740.032
epithelial cell migration open tracheal systemGO:0007427320.032
germarium derived egg chamber formationGO:00072931010.032
positive regulation of mitotic cell cycle phase transitionGO:1901992200.032
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.032
organonitrogen compound metabolic processGO:19015643180.032
glial cell migrationGO:0008347310.032
wound healingGO:0042060750.031
protein phosphorylationGO:00064681690.031
regulation of protein import into nucleusGO:0042306280.031
Mouse
heart field specificationGO:000312800.031
synapse assemblyGO:00074161430.031
positive regulation of kinase activityGO:0033674250.031
chromosome separationGO:0051304420.030
sister chromatid segregationGO:0000819920.030
positive regulation of intracellular signal transductionGO:19025331160.030
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encodedGO:000807110.030
regulation of phosphorylationGO:00423251470.030
positive regulation of cell proliferationGO:0008284470.030
Mouse
cortical cytoskeleton organizationGO:0030865290.030
protein transportGO:00150311550.030
Mouse
defense response to other organismGO:00985422250.030
regenerationGO:0031099160.030
Rat
matingGO:00076181200.029
purine nucleoside metabolic processGO:00422781270.029
positive regulation of protein phosphorylationGO:0001934340.029
canonical wnt signaling pathwayGO:0060070210.029
cellular response to chemical stimulusGO:00708871990.029
Mouse
negative regulation of protein modification processGO:0031400290.029
phosphorylationGO:00163102940.028
establishment of protein localization to organelleGO:0072594620.028
Mouse
positive regulation of nucleotide catabolic processGO:0030813460.028
dorsal closureGO:0007391790.028
regulation of mitotic cell cycle phase transitionGO:19019901300.028
epidermal growth factor receptor signaling pathwayGO:0007173580.028
cation transportGO:00068121100.028
jak stat cascadeGO:0007259490.028
defense response to bacteriumGO:00427421780.028
regulation of cell divisionGO:0051302720.027
organelle assemblyGO:00709251980.027
Zebrafish
positive regulation of nucleobase containing compound metabolic processGO:00459353320.027
Mouse
negative regulation of phosphate metabolic processGO:0045936450.027
receptor mediated endocytosisGO:0006898210.027
multicellular organism growthGO:0035264460.027
Mouse
renal system developmentGO:0072001720.026
Human Mouse
malpighian tubule developmentGO:0072002640.026
negative regulation of peptidyl tyrosine phosphorylationGO:005073260.026
maintenance of locationGO:0051235730.026
learning or memoryGO:00076111410.026
imaginal disc derived wing margin morphogenesisGO:0008587410.026
regulation of transmembrane transportGO:0034762270.026
branching morphogenesis of an epithelial tubeGO:0048754450.026
Mouse
regulation of stem cell proliferationGO:0072091400.026
Mouse
response to red or far red lightGO:000963920.026
peptidyl amino acid modificationGO:00181931050.026
sensory perceptionGO:00076001960.026
regulation of protein localization to nucleusGO:1900180290.026
Mouse
regulation of notch signaling pathwayGO:00085931000.026
leg disc morphogenesisGO:0007478800.026
regulation of epithelial cell migrationGO:0010632120.025
purine ribonucleotide catabolic processGO:00091541090.025
cell cycle g1 s phase transitionGO:0044843310.025
activation of anaphase promoting complex activityGO:005148810.025
regulation of mitotic sister chromatid segregationGO:0033047280.025
stem cell proliferationGO:0072089880.025
Mouse
regulation of innate immune responseGO:0045088710.024
negative regulation of synapse assemblyGO:0051964390.024
negative regulation of gene expressionGO:00106293870.024
Mouse
agingGO:00075681430.024
muscle cell developmentGO:0055001500.024
Zebrafish Mouse
muscle cell fate specificationGO:004269470.024
positive regulation of proteasomal protein catabolic processGO:1901800200.024
cell cycle phase transitionGO:00447701400.023
regulation of nuclear divisionGO:0051783580.023
organelle localizationGO:00516401480.023
dendrite regenerationGO:003110420.023

smo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.137
cancerDOID:16200.137
organ system cancerDOID:005068600.137
musculoskeletal system diseaseDOID:1700.098
disease of anatomical entityDOID:700.098
large intestine cancerDOID:567200.056
colorectal cancerDOID:925600.056
intestinal cancerDOID:1015500.056
gastrointestinal system cancerDOID:311900.056
colon cancerDOID:21900.031
cardiovascular system diseaseDOID:128700.030
aortic diseaseDOID:52000.030
artery diseaseDOID:005082800.030
vascular diseaseDOID:17800.030
aortic aneurysmDOID:362700.030
connective tissue diseaseDOID:6500.029