Drosophila melanogaster

67 known processes

MED16 (Dmel_CG5465)

Mediator complex subunit 16

(Aliases: med16,Trap95,Dmel\CG5465,CG5465,Med16,dTRAP95,Sin4/TRAP95)

MED16 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone acetylationGO:0016573380.233
transcription from rna polymerase ii promoterGO:00063663680.230
snrna 3 end processingGO:0034472140.165
cellular protein modification processGO:00064644380.143
regulation of transcription from rna polymerase ii promoterGO:00063573780.138
peptidyl lysine modificationGO:0018205570.132
negative regulation of rna biosynthetic processGO:19026792400.122
peptidyl lysine acetylationGO:0018394390.117
internal protein amino acid acetylationGO:0006475380.117
covalent chromatin modificationGO:00165691060.117
positive regulation of rna biosynthetic processGO:19026802660.115
protein acylationGO:0043543420.102
positive regulation of transcription dna templatedGO:00458932660.101
positive regulation of nucleic acid templated transcriptionGO:19035082660.098
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.093
positive regulation of cellular biosynthetic processGO:00313283160.091
chromatin organizationGO:00063252070.086
chromatin modificationGO:00165681470.086
growthGO:00400073590.078
response to biotic stimulusGO:00096072940.078
protein modification processGO:00362114380.078
g2 dna damage checkpointGO:0031572690.073
negative regulation of transcription dna templatedGO:00458922370.072
mitotic g2 m transition checkpointGO:0044818700.070
internal peptidyl lysine acetylationGO:0018393380.069
response to external biotic stimulusGO:00432072930.066
embryo development ending in birth or egg hatchingGO:00097921520.065
positive regulation of macromolecule metabolic processGO:00106044050.065
imaginal disc derived appendage developmentGO:00487373990.064
negative regulation of mitotic cell cycleGO:00459301090.063
negative regulation of cell cycleGO:00457861160.060
positive regulation of biosynthetic processGO:00098913160.060
histone modificationGO:00165701060.056
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.055
regulation of cell cycleGO:00517262910.054
body morphogenesisGO:001017120.054
protein acetylationGO:0006473390.052
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.052
positive regulation of nucleobase containing compound metabolic processGO:00459353320.051
negative regulation of cellular metabolic processGO:00313243820.050
cell cycle phase transitionGO:00447701400.050
positive regulation of nitrogen compound metabolic processGO:00511733540.050
peptidyl amino acid modificationGO:00181931050.048
imaginal disc derived appendage morphogenesisGO:00351143950.047
negative regulation of macromolecule biosynthetic processGO:00105582700.045
chromosome organizationGO:00512763600.044
mitotic dna damage checkpointGO:0044773740.044
mitotic cell cycle checkpointGO:0007093880.044
negative regulation of biosynthetic processGO:00098902770.044
negative regulation of cellular biosynthetic processGO:00313272770.043
regionalizationGO:00030024160.043
negative regulation of nucleic acid templated transcriptionGO:19035072400.043
camera type eye developmentGO:004301040.043
immune responseGO:00069552460.042
negative regulation of rna metabolic processGO:00512532510.042
mitotic g2 dna damage checkpointGO:0007095690.042
appendage morphogenesisGO:00351073970.040
positive regulation of macromolecule biosynthetic processGO:00105572830.040
regulation of immune system processGO:00026821760.040
appendage developmentGO:00487364010.039
cell proliferationGO:00082832990.038
leg disc morphogenesisGO:0007478800.038
regulation of cellular amino acid metabolic processGO:000652100.038
regulation of cell proliferationGO:00421271630.037
mitotic cell cycle phase transitionGO:00447721380.037
mitotic dna integrity checkpointGO:0044774750.037
post embryonic appendage morphogenesisGO:00351203850.037
positive regulation of gene expressionGO:00106282900.035
cellular protein localizationGO:00346131600.035
leg disc developmentGO:0035218920.035
response to other organismGO:00517072930.034
regulation of notch signaling pathwayGO:00085931000.033
positive regulation of rna metabolic processGO:00512542710.032
ncrna metabolic processGO:0034660430.032
regulation of cell differentiationGO:00455953020.032
chemotaxisGO:00069352490.032
organelle fissionGO:00482853400.031
negative regulation of nitrogen compound metabolic processGO:00511722650.031
regulation of mitotic cell cycleGO:00073461900.030
immune system processGO:00023763470.030
regulation of immune responseGO:00507761180.030
negative regulation of cell cycle phase transitionGO:19019881030.030
eye developmentGO:00016543230.029
single organism carbohydrate metabolic processGO:0044723720.029
meiotic nuclear divisionGO:00071261510.029
regulation of response to stressGO:00801342000.029
establishment or maintenance of cell polarityGO:00071631670.029
retina development in camera type eyeGO:006004140.029
endodermal cell differentiationGO:003598730.029
phosphorylationGO:00163102940.028
regulation of cell cycle phase transitionGO:19019871300.028
chromatin assembly or disassemblyGO:0006333520.027
positive regulation of cell communicationGO:00106472500.027
negative regulation of mitotic cell cycle phase transitionGO:19019911030.027
axon guidanceGO:00074112330.026
meiotic cell cycleGO:00513211710.026
regulation of cellular amine metabolic processGO:003323830.026
dna integrity checkpointGO:0031570810.026
imaginal disc derived leg morphogenesisGO:0007480800.025
regulation of meiosisGO:004002030.025
imaginal disc derived wing morphogenesisGO:00074763370.025
anterior posterior pattern specificationGO:00099521360.025
negative regulation of gene expressionGO:00106293870.025
regulation of mitotic cell cycle phase transitionGO:19019901300.025
photoreceptor cell differentiationGO:00465301700.024
notch signaling pathwayGO:00072191200.024
regulation of neurogenesisGO:00507671580.024
organic substance catabolic processGO:19015753080.024
catabolic processGO:00090564090.024
immune effector processGO:0002252980.024
regulation of synapse organizationGO:00508071100.023
snrna metabolic processGO:0016073140.023
regulation of molecular functionGO:00650092170.023
response to bacteriumGO:00096171980.023
negative regulation of nucleobase containing compound metabolic processGO:00459342610.023
regulation of cellular ketone metabolic processGO:001056530.023
eye photoreceptor cell developmentGO:0042462810.023
antimicrobial peptide productionGO:0002775460.023
response to organic substanceGO:00100332840.023
gastrulationGO:0007369700.023
tissue morphogenesisGO:00487292970.023
positive regulation of cellular amine metabolic processGO:003324000.022
response to abiotic stimulusGO:00096283410.022
cellular catabolic processGO:00442483720.021
wnt signaling pathwayGO:0016055980.021
snrna processingGO:0016180140.021
negative regulation of developmental processGO:00510932010.021
vesicle mediated transportGO:00161923810.021
regulation of multi organism processGO:00439001310.021
cellular amine metabolic processGO:0044106120.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
regulation of cell cycle processGO:00105641810.021
protein localizationGO:00081042840.020
cellular ketone metabolic processGO:0042180240.020
nuclear divisionGO:00002803320.020
cell deathGO:00082192790.020
rna processingGO:00063961470.020
neuroblast proliferationGO:0007405740.019
regulation of nervous system developmentGO:00519602480.019
cell cycle arrestGO:000705040.019
taxisGO:00423303040.019
amine metabolic processGO:0009308120.019
sensory organ morphogenesisGO:00905962600.019
regulation of intracellular signal transductionGO:19025312360.019
regulation of cellular response to stressGO:0080135890.019
g1 s transition of mitotic cell cycleGO:0000082310.019
regulation of gene silencingGO:0060968630.019
carbohydrate metabolic processGO:0005975820.019
cell adhesionGO:00071551360.018
lateral inhibitionGO:00463312060.018
antimicrobial humoral responseGO:0019730990.018
muscle organ developmentGO:00075171270.018
axonogenesisGO:00074092900.018
intracellular signal transductionGO:00355563000.018
chromatin remodelingGO:0006338720.018
dorsal ventral pattern formationGO:00099531330.018
negative regulation of response to stimulusGO:00485852580.018
regulation of response to biotic stimulusGO:0002831630.018
protein phosphorylationGO:00064681690.018
regulation of antimicrobial peptide biosynthetic processGO:0002805380.017
protein modification by small protein conjugation or removalGO:00706471060.017
positive regulation of signalingGO:00230562430.017
regulation of apoptotic processGO:00429811300.017
multi organism behaviorGO:00517051750.017
cell migrationGO:00164772380.017
peptide metabolic processGO:0006518800.017
biological adhesionGO:00226101380.017
regulation of humoral immune responseGO:0002920510.017
positive regulation of response to stimulusGO:00485843230.016
negative regulation of cell proliferationGO:0008285690.016
response to ionizing radiationGO:0010212320.016
photoreceptor cell developmentGO:0042461960.016
defense responseGO:00069523000.016
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.016
small molecule metabolic processGO:00442813050.016
cellular response to dna damage stimulusGO:00069742230.016
negative regulation of cell differentiationGO:00455961430.016
regulation of response to external stimulusGO:00321011150.016
neuron projection guidanceGO:00974852410.016
negative regulation of cell cycle processGO:00109481090.016
establishment of protein localizationGO:00451841630.015
regulation of immune effector processGO:0002697520.015
wing disc morphogenesisGO:00074723440.015
embryonic morphogenesisGO:00485982060.015
proteolysisGO:00065081920.015
methylationGO:0032259470.015
cell cycle g1 s phase transitionGO:0044843310.015
imaginal disc pattern formationGO:0007447910.015
positive regulation of molecular functionGO:00440931360.015
tube developmentGO:00352952440.014
response to extracellular stimulusGO:00099911160.014
cell cell signaling involved in cell fate commitmentGO:00451682100.014
g protein coupled receptor signaling pathwayGO:00071861360.014
dorsal ventral axis specificationGO:0009950660.014
response to lipopolysaccharideGO:003249640.014
signal transduction in response to dna damageGO:004277030.014
regulation of cell deathGO:00109411730.014
regulation of catalytic activityGO:00507901850.014
mrna splicing via spliceosomeGO:0000398730.014
posttranscriptional regulation of gene expressionGO:00106081450.014
oocyte dorsal ventral axis specificationGO:0007310340.013
mrna metabolic processGO:00160711240.013
neural precursor cell proliferationGO:0061351750.013
humoral immune responseGO:00069591170.013
small gtpase mediated signal transductionGO:0007264880.013
defense response to other organismGO:00985422250.013
negative regulation of signal transductionGO:00099682060.013
compound eye morphogenesisGO:00017452490.013
organonitrogen compound metabolic processGO:19015643180.013
muscle structure developmentGO:00610612240.013
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.013
mapk cascadeGO:00001651070.013
ubiquitin dependent protein catabolic processGO:0006511780.013
regulation of multicellular organismal developmentGO:20000264140.013
ameboidal type cell migrationGO:00016671510.013
cellular amino acid metabolic processGO:0006520610.013
transcription initiation from rna polymerase ii promoterGO:0006367250.013
regulation of production of molecular mediator of immune responseGO:0002700440.013
regulation of chromatin silencingGO:0031935360.013
response to oxygen containing compoundGO:19017002000.012
deathGO:00162652840.012
stem cell differentiationGO:00488631170.012
regulation of cell developmentGO:00602842150.012
positive regulation of signal transductionGO:00099672230.012
single organism intracellular transportGO:19025822070.012
sex comb developmentGO:004549880.012
rna methylationGO:000151020.012
eye photoreceptor cell differentiationGO:00017541450.012
defense response to bacteriumGO:00427421780.012
digestive tract morphogenesisGO:00485461270.012
connective tissue developmentGO:006144830.012
regulation of chromatin organizationGO:1902275320.012
regulation of defense responseGO:00313471020.012
modification dependent protein catabolic processGO:0019941780.012
cellular amide metabolic processGO:0043603800.012
camera type eye morphogenesisGO:004859320.012
eye morphogenesisGO:00485922600.012
regulation of mapk cascadeGO:0043408920.011
regulation of autophagyGO:0010506620.011
axon developmentGO:00615642970.011
histone h3 acetylationGO:0043966110.011
regulation of cellular protein metabolic processGO:00322682430.011
chaeta developmentGO:0022416970.011
homeostatic processGO:00425921990.011
negative regulation of nervous system developmentGO:0051961920.011
kidney developmentGO:000182230.011
single organism biosynthetic processGO:00447112060.011
cellular response to biotic stimulusGO:007121640.011
organic substance transportGO:00717022570.011
macromolecular complex assemblyGO:00650032560.011
endocytosisGO:00068973100.011
dna methylation or demethylationGO:004472840.011
cellular response to chemical stimulusGO:00708871990.011
innate immune responseGO:00450871440.011
positive regulation of heterochromatin assemblyGO:003145350.011
cellularizationGO:0007349900.011
embryonic development via the syncytial blastodermGO:00017001480.010
regulation of mrna splicing via spliceosomeGO:0048024640.010
digestive system developmentGO:00551231490.010
ras protein signal transductionGO:0007265880.010
protein ubiquitinationGO:0016567700.010
negative regulation of growthGO:0045926840.010
endoderm formationGO:000170630.010
rna 3 end processingGO:0031123450.010
regulation of phosphate metabolic processGO:00192202100.010
negative regulation of apoptotic processGO:0043066630.010
protein transportGO:00150311550.010
wing disc pattern formationGO:0035222660.010

MED16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.087
nervous system diseaseDOID:86300.031
cancerDOID:16200.015
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
musculoskeletal system diseaseDOID:1700.013