Drosophila melanogaster

91 known processes

msl-1 (Dmel_CG10385)

male-specific lethal 1

(Aliases: Msl-1,MSL-1,MSL1,MSL3,msl,km(2)B,CG10385,kmB,i94,MSL,Dmel\CG10385,mls-1,msl1,Msl 1-3,Msl1)

msl-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h4 k16 acetylationGO:004398440.981
Human
peptidyl lysine modificationGO:0018205570.707
Human
protein acetylationGO:0006473390.551
Human
histone h4 acetylationGO:0043967130.535
Human
regulation of chromatin silencingGO:0031935360.506
regulation of gene silencingGO:0060968630.450
gene silencingGO:00164581380.449
positive regulation of gene expressionGO:00106282900.399
positive regulation of rna biosynthetic processGO:19026802660.365
protein modification by small protein conjugationGO:0032446790.362
regulation of gene expression epigeneticGO:00400291280.349
positive regulation of nitrogen compound metabolic processGO:00511733540.340
positive regulation of rna metabolic processGO:00512542710.324
negative regulation of gene expressionGO:00106293870.323
covalent chromatin modificationGO:00165691060.323
Human
positive regulation of biosynthetic processGO:00098913160.284
chromatin modificationGO:00165681470.248
Human
positive regulation of nucleobase containing compound metabolic processGO:00459353320.241
positive regulation of proteolysisGO:0045862520.214
chromosome organizationGO:00512763600.213
Human
internal peptidyl lysine acetylationGO:0018393380.206
Human
positive regulation of cellular biosynthetic processGO:00313283160.199
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.193
negative regulation of cellular biosynthetic processGO:00313272770.190
chromatin organizationGO:00063252070.173
Human
localization of cellGO:00516742570.169
histone acetylationGO:0016573380.151
Human
protein modification by small protein conjugation or removalGO:00706471060.150
chromatin silencingGO:0006342760.133
dosage compensationGO:0007549160.126
cell migrationGO:00164772380.125
rna processingGO:00063961470.117
positive regulation of endopeptidase activityGO:0010950260.115
negative regulation of biosynthetic processGO:00098902770.112
histone modificationGO:00165701060.111
Human
negative regulation of nucleic acid templated transcriptionGO:19035072400.108
protein modification processGO:00362114380.105
Human
response to oxidative stressGO:0006979860.099
protein acylationGO:0043543420.095
Human
peptidyl lysine acetylationGO:0018394390.093
Human
internal protein amino acid acetylationGO:0006475380.093
Human
positive regulation of cysteine type endopeptidase activityGO:2001056240.091
cellular macromolecule localizationGO:00707272200.091
immune system processGO:00023763470.085
negative regulation of rna metabolic processGO:00512532510.084
regulation of cellular ketone metabolic processGO:001056530.084
ommochrome biosynthetic processGO:0006727190.080
anterograde synaptic vesicle transportGO:004849030.080
epithelium migrationGO:00901321480.080
cellular pigmentationGO:0033059120.078
positive regulation of nucleic acid templated transcriptionGO:19035082660.070
regulation of protein acetylationGO:190198370.068
negative regulation of neuron deathGO:1901215180.067
body morphogenesisGO:001017120.066
regulation of notch signaling pathwayGO:00085931000.065
macromolecular complex assemblyGO:00650032560.065
rna splicingGO:0008380830.065
cellular response to abiotic stimulusGO:0071214580.064
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.064
positive regulation of transcription dna templatedGO:00458932660.062
single organism cellular localizationGO:19025801800.062
negative regulation of transcription dna templatedGO:00458922370.061
negative regulation of gene expression epigeneticGO:0045814770.060
endocytosisGO:00068973100.060
protein localization to organelleGO:0033365820.057
chromatin remodelingGO:0006338720.057
regulation of synapse organizationGO:00508071100.056
peptidyl amino acid modificationGO:00181931050.055
Human
ameboidal type cell migrationGO:00016671510.054
regulation of apoptotic processGO:00429811300.053
regulation of chromatin organizationGO:1902275320.052
positive regulation of macromolecule biosynthetic processGO:00105572830.052
negative regulation of chromatin silencingGO:003193690.051
mrna splicing via spliceosomeGO:0000398730.049
epithelial cell developmentGO:00020642740.049
zymogen activationGO:0031638200.049
negative regulation of nucleobase containing compound metabolic processGO:00459342610.049
regulation of programmed cell deathGO:00430671520.048
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.047
chromatin assembly or disassemblyGO:0006333520.044
cellular protein modification processGO:00064644380.043
Human
negative regulation of molecular functionGO:0044092510.041
growthGO:00400073590.041
carboxylic acid metabolic processGO:0019752920.040
ovarian follicle cell migrationGO:00072971210.039
transcription from rna polymerase ii promoterGO:00063663680.039
homeostatic processGO:00425921990.038
ocellus pigment metabolic processGO:0046158190.038
positive regulation of peptidase activityGO:0010952290.038
mrna metabolic processGO:00160711240.037
autophagyGO:00069141080.037
positive regulation of response to stimulusGO:00485843230.036
establishment of localization in cellGO:00516494020.036
regulation of response to stressGO:00801342000.035
negative regulation of rna biosynthetic processGO:19026792400.034
regulation of chromatin modificationGO:1903308280.034
male gamete generationGO:00482322010.032
establishment of organelle localizationGO:00516561220.032
regulation of cellular amino acid metabolic processGO:000652100.031
organelle localizationGO:00516401480.031
modification dependent macromolecule catabolic processGO:0043632790.031
regulation of cellular amine metabolic processGO:003323830.030
protein dna complex subunit organizationGO:0071824860.030
regulation of synapse structure and activityGO:00508031280.030
cellular catabolic processGO:00442483720.030
regulation of proteolysisGO:0030162870.030
regulation of autophagyGO:0010506620.030
regulation of cell proliferationGO:00421271630.030
regulation of mrna processingGO:0050684710.030
notch signaling pathwayGO:00072191200.029
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.029
amine metabolic processGO:0009308120.029
negative regulation of signal transductionGO:00099682060.028
hematopoietic or lymphoid organ developmentGO:0048534570.027
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.027
negative regulation of cell communicationGO:00106482230.027
programmed cell deathGO:00125012570.026
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.026
vesicle localizationGO:0051648550.026
tissue migrationGO:00901301550.026
regulation of mrna metabolic processGO:1903311720.026
regulation of rna splicingGO:0043484690.025
regulation of steroid metabolic processGO:001921820.025
regulation of organelle organizationGO:00330431960.024
cellular response to dna damage stimulusGO:00069742230.024
actin filament based processGO:00300292200.023
negative regulation of response to stimulusGO:00485852580.023
phagocytosisGO:00069092150.023
synaptic transmissionGO:00072682880.022
positive regulation of cell communicationGO:00106472500.022
regulation of alternative mrna splicing via spliceosomeGO:0000381600.022
regionalizationGO:00030024160.022
cellular response to chemical stimulusGO:00708871990.021
deathGO:00162652840.021
regulation of meiosisGO:004002030.021
cell deathGO:00082192790.020
cell divisionGO:00513012480.020
determination of adult lifespanGO:00083401370.020
regulation of protein metabolic processGO:00512462560.020
cytoplasmic transportGO:00164821300.020
ocellus pigmentationGO:0033060190.020
epithelial cell migrationGO:00106311480.020
immune system developmentGO:0002520570.019
regulation of cellular protein metabolic processGO:00322682430.019
notch receptor processingGO:0007220130.019
rna splicing via transesterification reactionsGO:0000375730.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
negative regulation of programmed cell deathGO:0043069720.019
gene silencing by rnaGO:0031047570.019
enzyme linked receptor protein signaling pathwayGO:00071671790.018
vesicle mediated transportGO:00161923810.018
anterograde axon cargo transportGO:000808960.018
oxoacid metabolic processGO:00434361030.018
cytokinesisGO:0000910900.018
germ cell migrationGO:0008354430.017
cellular amine metabolic processGO:0044106120.017
organic acid metabolic processGO:00060821030.017
germarium derived egg chamber formationGO:00072931010.017
proteolysisGO:00065081920.017
regulation of mrna splicing via spliceosomeGO:0048024640.017
eye pigment granule organizationGO:0008057120.017
dna integrity checkpointGO:0031570810.017
negative regulation of notch signaling pathwayGO:0045746410.017
smoothened signaling pathwayGO:0007224490.016
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.016
regulation of proteasomal protein catabolic processGO:0061136390.016
regulation of growthGO:00400082330.016
activation of cysteine type endopeptidase activityGO:0097202170.016
ovarian follicle cell developmentGO:00307072480.016
regulation of peptidase activityGO:0052547390.016
macromolecule catabolic processGO:00090571610.016
cellular ketone metabolic processGO:0042180240.015
cellular homeostasisGO:0019725800.015
negative regulation of gene silencing by rnaGO:006096790.015
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.015
hemopoiesisGO:0030097460.015
regulation of histone acetylationGO:003506570.015
cytoskeleton dependent intracellular transportGO:0030705440.015
eye developmentGO:00016543230.015
alternative mrna splicing via spliceosomeGO:0000380600.015
posttranscriptional regulation of gene expressionGO:00106081450.014
protein transportGO:00150311550.014
compound eye developmentGO:00487493070.014
regulation of cell deathGO:00109411730.014
eye pigment metabolic processGO:0042441330.014
regulation of cysteine type endopeptidase activityGO:2000116270.014
proteasomal protein catabolic processGO:0010498590.014
embryo development ending in birth or egg hatchingGO:00097921520.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
response to ionizing radiationGO:0010212320.013
connective tissue developmentGO:006144830.013
organic substance transportGO:00717022570.013
cell growthGO:00160491080.013
anatomical structure homeostasisGO:0060249970.013
dna damage checkpointGO:0000077780.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.012
wing disc morphogenesisGO:00074723440.012
cell motilityGO:00488702510.012
regulation of mitotic cell cycleGO:00073461900.012
cellular divalent inorganic cation homeostasisGO:0072503230.012
negative regulation of bmp signaling pathwayGO:0030514120.012
establishment of protein localizationGO:00451841630.012
response to abiotic stimulusGO:00096283410.012
photoreceptor cell fate commitmentGO:0046552410.012
protein ubiquitinationGO:0016567700.012
regulation of cell cycleGO:00517262910.012
imaginal disc derived leg segmentationGO:0036011260.011
regulation of nervous system developmentGO:00519602480.011
ommochrome metabolic processGO:0046152190.011
ribonucleoprotein complex biogenesisGO:0022613310.011
negative regulation of cellular response to oxidative stressGO:190040810.011
regulation of histone modificationGO:0031056200.011
protein localizationGO:00081042840.011
imaginal disc fusion thorax closureGO:0046529190.011
response to hypoxiaGO:0001666530.011
multicellular organismal agingGO:00102591400.011
negative regulation of neuron apoptotic processGO:0043524140.011
rrna processingGO:000636430.011
negative regulation of nitrogen compound metabolic processGO:00511722650.011
regulation of macroautophagyGO:0016241150.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
pigment granule organizationGO:0048753120.010
cellular macromolecular complex assemblyGO:00346221530.010
positive regulation of cell deathGO:0010942690.010

msl-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.014