Drosophila melanogaster

18 known processes

phol (Dmel_CG3445)

pleiohomeotic like

(Aliases: CG3445,Dmel\CG3445,PHOL,Phol)

phol biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cellular biosynthetic processGO:00313272770.248
Human Mouse Rat Fly
negative regulation of transcription dna templatedGO:00458922370.219
Human Mouse Rat Fly
negative regulation of biosynthetic processGO:00098902770.214
Human Mouse Rat Fly
transcription from rna polymerase ii promoterGO:00063663680.194
Human Mouse Rat
negative regulation of rna biosynthetic processGO:19026792400.192
Human Mouse Rat Fly
dorsal closureGO:0007391790.184
imaginal disc derived appendage morphogenesisGO:00351143950.183
appendage morphogenesisGO:00351073970.165
negative regulation of cellular metabolic processGO:00313243820.165
Human Mouse Rat Fly
multicellular organism growthGO:0035264460.161
gland developmentGO:00487321910.155
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.149
Human Mouse Rat Fly
embryonic morphogenesisGO:00485982060.134
protein modification processGO:00362114380.128
negative regulation of nucleic acid templated transcriptionGO:19035072400.126
Human Mouse Rat Fly
regulation of transcription from rna polymerase ii promoterGO:00063573780.119
Human Mouse Rat
positive regulation of biosynthetic processGO:00098913160.112
Rat Fly
taxisGO:00423303040.104
regulation of developmental growthGO:00486381740.102
cellular protein modification processGO:00064644380.101
female meiotic divisionGO:0007143700.100
meiotic chromosome segregationGO:0045132590.100
negative regulation of macromolecule biosynthetic processGO:00105582700.098
Human Mouse Rat Fly
negative regulation of nucleobase containing compound metabolic processGO:00459342610.095
Human Mouse Rat Fly
actin cytoskeleton organizationGO:00300362060.090
growthGO:00400073590.085
positive regulation of cellular catabolic processGO:0031331950.085
mitotic cell cycle phase transitionGO:00447721380.074
negative regulation of nitrogen compound metabolic processGO:00511722650.072
Human Mouse Rat Fly
tissue deathGO:00162711020.071
regulation of intracellular signal transductionGO:19025312360.070
meiotic nuclear divisionGO:00071261510.069
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.068
Rat
negative regulation of gene expressionGO:00106293870.067
response to abiotic stimulusGO:00096283410.063
Human Mouse
positive regulation of response to stimulusGO:00485843230.062
meiotic cell cycleGO:00513211710.062
positive regulation of cell communicationGO:00106472500.062
regulation of phosphorus metabolic processGO:00511742100.060
cellular macromolecule catabolic processGO:00442651360.060
neurological system processGO:00508773580.059
phosphorylationGO:00163102940.059
developmental growthGO:00485892800.058
imaginal disc derived appendage developmentGO:00487373990.058
positive regulation of nitrogen compound metabolic processGO:00511733540.057
Rat Fly
negative regulation of rna metabolic processGO:00512532510.057
Human Mouse Rat Fly
positive regulation of signal transductionGO:00099672230.054
positive regulation of nucleobase containing compound metabolic processGO:00459353320.054
Rat Fly
positive regulation of transcription dna templatedGO:00458932660.054
Rat Fly
digestive tract developmentGO:00485651490.053
positive regulation of signalingGO:00230562430.053
regulation of dna metabolic processGO:0051052340.053
post embryonic appendage morphogenesisGO:00351203850.051
embryo development ending in birth or egg hatchingGO:00097921520.051
Mouse
synapse organizationGO:00508081960.048
single organism behaviorGO:00447083910.048
intracellular signal transductionGO:00355563000.047
regulation of cellular protein metabolic processGO:00322682430.047
regulation of mitotic cell cycle phase transitionGO:19019901300.046
regulation of cell proliferationGO:00421271630.045
meiotic cell cycle processGO:19030461320.044
chemosensory behaviorGO:00076351060.042
regulation of multicellular organismal developmentGO:20000264140.041
regulation of phosphate metabolic processGO:00192202100.041
digestive system developmentGO:00551231490.041
cognitionGO:00508901410.040
purine nucleotide metabolic processGO:00061631460.038
cell deathGO:00082192790.038
regulation of cellular catabolic processGO:00313291570.038
deathGO:00162652840.037
wing disc morphogenesisGO:00074723440.037
small gtpase mediated signal transductionGO:0007264880.037
purine ribonucleoside metabolic processGO:00461281270.037
digestive tract morphogenesisGO:00485461270.037
regulation of cellular amino acid metabolic processGO:000652100.035
programmed cell deathGO:00125012570.035
actin filament based processGO:00300292200.035
cell proliferationGO:00082832990.034
axon developmentGO:00615642970.034
segmentationGO:00352822070.034
nucleotide metabolic processGO:00091171610.033
axon guidanceGO:00074112330.033
nuclear divisionGO:00002803320.033
eye developmentGO:00016543230.033
Mouse
salivary gland morphogenesisGO:00074351450.032
macromolecule catabolic processGO:00090571610.032
central nervous system developmentGO:00074172010.032
mrna metabolic processGO:00160711240.032
positive regulation of cellular component organizationGO:00511301560.032
regulation of anatomical structure sizeGO:00900661630.031
salivary gland developmentGO:00074311620.031
histolysisGO:00075591020.031
regulation of protein metabolic processGO:00512462560.031
embryonic pattern specificationGO:00098801740.030
immune system processGO:00023763470.029
organonitrogen compound metabolic processGO:19015643180.029
endocytosisGO:00068973100.029
positive regulation of rna biosynthetic processGO:19026802660.029
Rat Fly
negative regulation of developmental processGO:00510932010.029
heterocycle catabolic processGO:00467001660.029
purine nucleoside triphosphate metabolic processGO:00091441190.029
gland morphogenesisGO:00226121450.028
response to starvationGO:0042594970.028
protein k48 linked ubiquitinationGO:007093630.028
developmental programmed cell deathGO:00106231380.028
immune system developmentGO:0002520570.028
gravitaxisGO:0042332260.028
columnar cuboidal epithelial cell differentiationGO:00020652560.028
protein phosphorylationGO:00064681690.027
response to nitrogen compoundGO:1901698900.027
regulation of cell cycle phase transitionGO:19019871300.027
tube developmentGO:00352952440.027
small molecule metabolic processGO:00442813050.026
gastrulation with mouth forming firstGO:0001703360.026
chromatin modificationGO:00165681470.026
Fly
positive regulation of macromolecule biosynthetic processGO:00105572830.026
Rat Fly
positive regulation of nucleic acid templated transcriptionGO:19035082660.026
Rat Fly
regulation of molecular functionGO:00650092170.026
organic cyclic compound catabolic processGO:19013611680.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.025
salivary gland histolysisGO:0035070880.025
cellular amine metabolic processGO:0044106120.025
catabolic processGO:00090564090.025
spermatogenesisGO:00072832000.025
Mouse
localization of cellGO:00516742570.025
regulation of organelle organizationGO:00330431960.024
axonogenesisGO:00074092900.024
nucleoside catabolic processGO:00091641120.024
chromosome segregationGO:00070591570.024
guanosine containing compound metabolic processGO:1901068740.024
agingGO:00075681430.024
actomyosin structure organizationGO:0031032560.023
aromatic compound catabolic processGO:00194391660.023
regulation of cell cycleGO:00517262910.023
ras protein signal transductionGO:0007265880.023
sex differentiationGO:0007548810.023
Human
purine ribonucleotide metabolic processGO:00091501450.023
guanosine containing compound catabolic processGO:1901069740.023
glycosyl compound metabolic processGO:19016571270.023
response to reactive oxygen speciesGO:0000302240.022
gtp metabolic processGO:0046039720.022
ribose phosphate metabolic processGO:00196931450.022
multi organism behaviorGO:00517051750.022
nucleotide catabolic processGO:00091661090.022
ribonucleotide catabolic processGO:00092611090.022
hemopoiesisGO:0030097460.022
ribonucleoside metabolic processGO:00091191270.022
cellular protein catabolic processGO:0044257830.022
positive regulation of catabolic processGO:00098961050.022
regulation of catabolic processGO:00098941700.022
exocrine system developmentGO:00352721620.022
oocyte microtubule cytoskeleton organizationGO:0016325350.022
connective tissue developmentGO:006144830.022
purine ribonucleotide catabolic processGO:00091541090.021
wnt signaling pathwayGO:0016055980.021
cellular catabolic processGO:00442483720.021
proteolysisGO:00065081920.021
imaginal disc derived wing morphogenesisGO:00074763370.020
organic substance catabolic processGO:19015753080.020
hematopoietic or lymphoid organ developmentGO:0048534570.020
autophagic cell deathGO:0048102830.020
nucleobase containing small molecule metabolic processGO:00550861740.020
negative regulation of protein metabolic processGO:0051248850.020
response to gravityGO:0009629260.020
cellular response to nitrogen compoundGO:1901699510.020
regulation of catalytic activityGO:00507901850.020
cellular nitrogen compound catabolic processGO:00442701650.020
covalent chromatin modificationGO:00165691060.020
regulation of cell cycle processGO:00105641810.019
mrna processingGO:00063971040.019
cellular macromolecular complex assemblyGO:00346221530.019
protein modification by small protein conjugationGO:0032446790.019
regulation of cellular ketone metabolic processGO:001056530.019
response to nutrient levelsGO:00316671140.019
response to organic cyclic compoundGO:0014070890.019
regulation of mapk cascadeGO:0043408920.018
cell agingGO:000756920.018
phagocytosisGO:00069092150.018
establishment or maintenance of cytoskeleton polarityGO:0030952440.018
regulation of cellular component biogenesisGO:00440872010.018
nucleoside phosphate catabolic processGO:19012921100.018
response to other organismGO:00517072930.018
eye morphogenesisGO:00485922600.018
Mouse
positive regulation of cellular component biogenesisGO:0044089800.018
camera type eye developmentGO:004301040.018
Mouse
appendage developmentGO:00487364010.018
positive regulation of cell motilityGO:200014730.018
single organism biosynthetic processGO:00447112060.018
Zebrafish
regulation of cell shapeGO:00083601130.018
establishment or maintenance of cell polarityGO:00071631670.018
regulation of lamellipodium assemblyGO:0010591150.018
positive regulation of intracellular signal transductionGO:19025331160.018
tube morphogenesisGO:00352391910.017
regulation of alternative mrna splicing via spliceosomeGO:0000381600.017
mitotic nuclear divisionGO:00070672130.017
regulation of purine nucleotide metabolic processGO:1900542620.017
positive regulation of cell proliferationGO:0008284470.017
carboxylic acid metabolic processGO:0019752920.017
signal transduction by phosphorylationGO:00230141070.017
positive regulation of cellular biosynthetic processGO:00313283160.017
Rat Fly
male gamete generationGO:00482322010.017
Mouse
positive regulation of phosphorus metabolic processGO:00105621390.017
nucleobase containing compound catabolic processGO:00346551650.017
regulation of mrna metabolic processGO:1903311720.017
chaeta developmentGO:0022416970.017
epithelial cell differentiationGO:00308553220.017
heart processGO:0003015370.017
protein ubiquitinationGO:0016567700.016
positive regulation of phosphate metabolic processGO:00459371390.016
purine nucleoside metabolic processGO:00422781270.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
defense responseGO:00069523000.016
chemotaxisGO:00069352490.016
gtp catabolic processGO:0006184720.016
protein modification by small protein conjugation or removalGO:00706471060.016
regulation of mrna processingGO:0050684710.016
salivary gland cell autophagic cell deathGO:0035071830.016
protein catabolic processGO:00301631010.016
proteolysis involved in cellular protein catabolic processGO:0051603830.016
regulation of gene expression epigeneticGO:00400291280.016
Fly
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.016
Human Mouse Rat
sensory organ morphogenesisGO:00905962600.016
Mouse
cellular response to chemical stimulusGO:00708871990.016
Rat
locomotory behaviorGO:00076261760.015
establishment or maintenance of bipolar cell polarityGO:0061245340.015
regulation of cellular amine metabolic processGO:003323830.015
negative regulation of signalingGO:00230572190.015
imaginal disc derived leg morphogenesisGO:0007480800.015
chaeta morphogenesisGO:0008407420.015
ribonucleotide metabolic processGO:00092591450.015
protein localizationGO:00081042840.015
embryonic development via the syncytial blastodermGO:00017001480.015
muscle structure developmentGO:00610612240.015
cellular lipid metabolic processGO:0044255830.015
regulation of multicellular organism growthGO:0040014400.015
organonitrogen compound biosynthetic processGO:19015661170.014
regulation of blood circulationGO:1903522210.014
regulation of ras protein signal transductionGO:0046578930.014
carbohydrate derivative metabolic processGO:19011352170.014
single organism intracellular transportGO:19025822070.014
cell cycle phase transitionGO:00447701400.014
heart contractionGO:0060047260.014
nucleoside triphosphate metabolic processGO:00091411200.014
negative regulation of response to stimulusGO:00485852580.014
secondary metabolic processGO:0019748750.014
regionalizationGO:00030024160.014
Mouse
eye photoreceptor cell fate commitmentGO:0042706370.014
neural precursor cell proliferationGO:0061351750.013
morphogenesis of embryonic epitheliumGO:0016331940.013
regulation of cell differentiationGO:00455953020.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
cellular response to organic substanceGO:00713101320.013
Rat
apoptotic processGO:00069151590.013
olfactory behaviorGO:0042048970.013
body morphogenesisGO:001017120.013
alternative mrna splicing via spliceosomeGO:0000380600.013
negative regulation of cellular protein metabolic processGO:0032269850.013
regulation of compound eye cone cell fate specificationGO:004268240.013
cellular amino acid metabolic processGO:0006520610.013
macromolecular complex assemblyGO:00650032560.013
protein processingGO:0016485680.013
gastrulation involving germ band extensionGO:0010004360.013
axis specificationGO:00097981670.013
regulation of nucleotide metabolic processGO:0006140620.013
carbohydrate derivative catabolic processGO:19011361180.013
negative regulation of cell communicationGO:00106482230.013
regulation of growthGO:00400082330.013
purine nucleotide catabolic processGO:00061951090.013
response to organonitrogen compoundGO:0010243750.013
gastrulationGO:0007369700.013
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.013
photoreceptor cell fate commitmentGO:0046552410.013
oxoacid metabolic processGO:00434361030.013
blood circulationGO:0008015260.013
cellular response to endogenous stimulusGO:0071495800.013
epidermal growth factor receptor signaling pathwayGO:0007173580.012
actin filament organizationGO:00070151260.012
defense response to other organismGO:00985422250.012
organelle fissionGO:00482853400.012
regulation of wnt signaling pathwayGO:0030111680.012
hematopoietic progenitor cell differentiationGO:000224410.012
intracellular steroid hormone receptor signaling pathwayGO:0030518120.012
protein maturationGO:0051604710.012
regulation of mitotic cell cycleGO:00073461900.012
vesicle mediated transportGO:00161923810.012
circulatory system processGO:0003013370.012
regulation of programmed cell deathGO:00430671520.012
cell fate specificationGO:0001708710.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
epithelial cell migration open tracheal systemGO:0007427320.012
larval developmentGO:00021641040.012
organophosphate catabolic processGO:00464341120.012
response to biotic stimulusGO:00096072940.012
protein complex assemblyGO:00064612000.012
single organism catabolic processGO:00447122280.012
determination of adult lifespanGO:00083401370.011
peptidyl amino acid modificationGO:00181931050.011
regulation of gtpase activityGO:0043087440.011
tor signalingGO:0031929320.011
oocyte microtubule cytoskeleton polarizationGO:0008103220.011
synaptic transmissionGO:00072682880.011
inositol lipid mediated signalingGO:004801740.011
positive regulation of gene expressionGO:00106282900.011
Mouse Rat Fly
organic substance transportGO:00717022570.011
ribonucleoside catabolic processGO:00424541120.011
positive regulation of cellular protein metabolic processGO:00322701180.011
positive regulation of mitotic cell cycle phase transitionGO:1901992200.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
positive regulation of organelle organizationGO:0010638650.011
mapk cascadeGO:00001651070.011
establishment of localization in cellGO:00516494020.011
regulation of response to stressGO:00801342000.011
positive regulation of nucleotide metabolic processGO:0045981550.011
regulation of protein modification processGO:00313991120.011
reproductive behaviorGO:00190981220.011
regulation of rna splicingGO:0043484690.011
purine ribonucleoside catabolic processGO:00461301120.011
regulation of cell morphogenesisGO:00226041630.011
purine containing compound metabolic processGO:00725211550.010
organelle assemblyGO:00709251980.010
negative regulation of cell cycle phase transitionGO:19019881030.010
negative regulation of cell cycle processGO:00109481090.010
regulation of translationGO:0006417560.010
embryonic axis specificationGO:00005781070.010
dendrite morphogenesisGO:00488131990.010
Fly
response to temperature stimulusGO:00092661060.010
metaphase anaphase transition of cell cycleGO:0044784280.010
regulation of actin cytoskeleton organizationGO:0032956420.010
positive regulation of cell differentiationGO:0045597640.010
erbb signaling pathwayGO:0038127580.010
epithelial cell developmentGO:00020642740.010
regulation of gene silencingGO:0060968630.010

phol disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
nervous system diseaseDOID:86300.014
central nervous system diseaseDOID:33100.012
organ system cancerDOID:005068600.012