IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Cyp28d1 (Dmel_CG10833)

CG10833 gene product from transcript CG10833-RA

(Aliases: CG10833,Dmel\CG10833,28d1)

Entrez: 33749
FLYBASE: FBgn0031689
UniProtKB: Q9VMT5

Process Predictions
Disease Predictions

Cyp28d1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
insecticide metabolic process	GO:0017143	2	0.926	Fly
insecticide catabolic process	GO:0046701	1	0.859	Fly
medium chain fatty acid metabolic process	GO:0051791	1	0.828	Fly
sensory perception of smell	GO:0007608	80	0.721	Fly
secondary metabolite catabolic process	GO:0090487	1	0.715	Fly
fat soluble vitamin biosynthetic process	GO:0042362	1	0.559	Human
response to mercury ion	GO:0046689	3	0.467	Fly
steroid catabolic process	GO:0006706	1	0.381	Human
multi organism behavior	GO:0051705	175	0.345	Fly
toxin metabolic process	GO:0009404	2	0.345	Fly
terpenoid metabolic process	GO:0006721	7	0.345	Human
sensory perception of chemical stimulus	GO:0007606	116	0.341	Fly
anion homeostasis	GO:0055081	3	0.333	Rat
cellular ketone metabolic process	GO:0042180	24	0.297	Fly
xenobiotic catabolic process	GO:0042178	1	0.296	Fly
hormone metabolic process	GO:0042445	33	0.289	Fly
cellular nitrogen compound catabolic process	GO:0044270	165	0.283	Human
aggressive behavior	GO:0002118	63	0.240	Fly
response to xenobiotic stimulus	GO:0009410	5	0.230	Zebrafish Fly
organonitrogen compound catabolic process	GO:1901565	128	0.214	Human
neurological system process	GO:0050877	358	0.211	Fly
ketone biosynthetic process	GO:0042181	16	0.200	Fly
organic hydroxy compound biosynthetic process	GO:1901617	21	0.195	Human Fly
response to insecticide	GO:0017085	14	0.191	Fly
organic cyclic compound catabolic process	GO:1901361	168	0.189	Human
fat soluble vitamin metabolic process	GO:0006775	1	0.186	Human
lauric acid metabolic process	GO:0048252	1	0.172	Fly
vitamin biosynthetic process	GO:0009110	1	0.159	Human
ecdysteroid biosynthetic process	GO:0045456	15	0.159	Fly
sensory perception	GO:0007600	196	0.147	Fly
cellular hormone metabolic process	GO:0034754	23	0.145	Fly
positive regulation of macromolecule metabolic process	GO:0010604	405	0.141	Mouse
small molecule metabolic process	GO:0044281	305	0.140	Human Fly
organic acid metabolic process	GO:0006082	103	0.139	Fly
polyol biosynthetic process	GO:0046173	3	0.128	Human
organic substance catabolic process	GO:1901575	308	0.125	Human
lipid metabolic process	GO:0006629	121	0.122	Human Fly
ecdysteroid metabolic process	GO:0045455	19	0.117	Fly
single organism biosynthetic process	GO:0044711	206	0.115	Human Fly
response to alkaloid	GO:0043279	26	0.115	Fly
response to organic substance	GO:0010033	284	0.111	Rat Fly
sterol biosynthetic process	GO:0016126	9	0.104	Fly
catabolic process	GO:0009056	409	0.103	Human Fly
response to temperature stimulus	GO:0009266	106	0.101	Fly
cellular response to xenobiotic stimulus	GO:0071466	5	0.099	Fly
single organism catabolic process	GO:0044712	228	0.096	Human Fly
organonitrogen compound metabolic process	GO:1901564	318	0.090	Human
carboxylic acid metabolic process	GO:0019752	92	0.089	Fly
steroid biosynthetic process	GO:0006694	16	0.087	Human Fly
cellular catabolic process	GO:0044248	372	0.087	Human Fly
lipid catabolic process	GO:0016042	21	0.086	Human
secondary metabolic process	GO:0019748	75	0.083	Fly
xenobiotic metabolic process	GO:0006805	5	0.079	Fly
lipid biosynthetic process	GO:0008610	46	0.079	Human Fly
alcohol biosynthetic process	GO:0046165	14	0.079	Human Fly
toxin catabolic process	GO:0009407	1	0.077	Fly
ecdysone biosynthetic process	GO:0006697	9	0.074	Fly
homeostatic process	GO:0042592	199	0.073	Rat
organic hydroxy compound metabolic process	GO:1901615	83	0.071	Human Fly
growth	GO:0040007	359	0.066	Fly
positive regulation of gene expression	GO:0010628	290	0.065	Mouse
hormone biosynthetic process	GO:0042446	20	0.064	Fly
ecdysone metabolic process	GO:0008205	11	0.063	Fly
single organism behavior	GO:0044708	391	0.058	Fly
cellular response to chemical stimulus	GO:0070887	199	0.057	Fly
response to organic cyclic compound	GO:0014070	89	0.055	Rat Fly
response to organophosphorus	GO:0046683	2	0.054	Fly
cellular ion homeostasis	GO:0006873	39	0.051	Rat
oxoacid metabolic process	GO:0043436	103	0.050	Fly
regulation of hormone levels	GO:0010817	40	0.050	Fly
cellular lipid metabolic process	GO:0044255	83	0.050	Human Fly
response to organonitrogen compound	GO:0010243	75	0.049	Fly
response to caffeine	GO:0031000	12	0.048	Fly
response to extracellular stimulus	GO:0009991	116	0.048	Rat
regulation of growth	GO:0040008	233	0.047	Fly
response to nutrient levels	GO:0031667	114	0.047	Rat
heterocycle catabolic process	GO:0046700	166	0.044
vitamin metabolic process	GO:0006766	2	0.044	Human
aromatic compound catabolic process	GO:0019439	166	0.043
alcohol metabolic process	GO:0006066	25	0.043	Human Fly
positive regulation of multicellular organismal process	GO:0051240	143	0.043	Rat
regulation of blood circulation	GO:1903522	21	0.042	Rat
regulation of developmental growth	GO:0048638	174	0.041	Fly
androgen metabolic process	GO:0008209	1	0.041
oxidation reduction process	GO:0055114	123	0.039	Human Mouse Rat Fly
isoprenoid metabolic process	GO:0006720	8	0.039	Human
regulation of anatomical structure size	GO:0090066	163	0.039	Rat
developmental growth	GO:0048589	280	0.038	Fly
benzene containing compound metabolic process	GO:0042537	3	0.038
cellular chemical homeostasis	GO:0055082	40	0.037	Rat
steroid metabolic process	GO:0008202	20	0.037	Human Fly
small molecule biosynthetic process	GO:0044283	37	0.037	Human Fly
regulation of system process	GO:0044057	36	0.035	Rat
chemical homeostasis	GO:0048878	92	0.035	Rat
multi multicellular organism process	GO:0044706	123	0.035
cellular homeostasis	GO:0019725	80	0.034	Rat
response to lipopolysaccharide	GO:0032496	4	0.034
appendage development	GO:0048736	401	0.034
ion homeostasis	GO:0050801	55	0.033	Rat
response to abiotic stimulus	GO:0009628	341	0.032	Fly
sterol metabolic process	GO:0016125	12	0.030	Fly
response to purine containing compound	GO:0014074	12	0.030	Fly
response to nitrogen compound	GO:1901698	90	0.029	Fly
response to endogenous stimulus	GO:0009719	119	0.028	Rat Fly
pigment metabolic process involved in pigmentation	GO:0043474	33	0.028
cellular amino acid metabolic process	GO:0006520	61	0.027
response to oxygen containing compound	GO:1901700	200	0.027
endocytosis	GO:0006897	310	0.025
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.025
imaginal disc derived appendage development	GO:0048737	399	0.024
carbohydrate derivative metabolic process	GO:1901135	217	0.024
wing disc morphogenesis	GO:0007472	344	0.022
post embryonic appendage morphogenesis	GO:0035120	385	0.022
monocarboxylic acid metabolic process	GO:0032787	29	0.022	Fly
taxis	GO:0042330	304	0.021
imaginal disc derived wing morphogenesis	GO:0007476	337	0.021
sensory organ morphogenesis	GO:0090596	260	0.020
gland development	GO:0048732	191	0.020
single organism carbohydrate metabolic process	GO:0044723	72	0.020
carbohydrate derivative catabolic process	GO:1901136	118	0.020
morphogenesis of an epithelium	GO:0002009	276	0.020
nucleobase containing small molecule metabolic process	GO:0055086	174	0.020
tergite morphogenesis	GO:0007490	1	0.020
circulatory system process	GO:0003013	37	0.020	Rat
fatty acid metabolic process	GO:0006631	20	0.020	Fly
regulation of transport	GO:0051049	181	0.019
developmental pigmentation	GO:0048066	68	0.019
response to hormone	GO:0009725	45	0.019	Rat
vesicle mediated transport	GO:0016192	381	0.019
salivary gland morphogenesis	GO:0007435	145	0.019
death	GO:0016265	284	0.018
camera type eye development	GO:0043010	4	0.018
regulation of localization	GO:0032879	275	0.018
positive regulation of response to stimulus	GO:0048584	323	0.018
hormone catabolic process	GO:0042447	3	0.017
eye development	GO:0001654	323	0.017
carbohydrate metabolic process	GO:0005975	82	0.017
response to inorganic substance	GO:0010035	44	0.017	Rat Fly
aging	GO:0007568	143	0.017	Rat
ribonucleoside metabolic process	GO:0009119	127	0.016
response to toxic substance	GO:0009636	22	0.016	Fly
cellular response to oxygen containing compound	GO:1901701	79	0.016
response to ddt	GO:0046680	5	0.016	Fly
epithelial cell development	GO:0002064	274	0.016
defense response	GO:0006952	300	0.016	Fly
phagocytosis	GO:0006909	215	0.016
regulation of behavior	GO:0050795	75	0.016
inter male aggressive behavior	GO:0002121	60	0.016
purine containing compound metabolic process	GO:0072521	155	0.016
response to hexose	GO:0009746	3	0.016
regulation of reproductive process	GO:2000241	54	0.016
protein modification process	GO:0036211	438	0.015
thermosensory behavior	GO:0040040	19	0.015	Fly
response to glucose	GO:0009749	2	0.015
telencephalon development	GO:0021537	2	0.015
embryo development ending in birth or egg hatching	GO:0009792	152	0.015
response to metal ion	GO:0010038	23	0.015	Rat Fly
nucleobase containing compound catabolic process	GO:0034655	165	0.014
compound eye development	GO:0048749	307	0.014
midgut development	GO:0007494	23	0.014
cell death	GO:0008219	279	0.014
response to radiation	GO:0009314	155	0.014
response to bacterium	GO:0009617	198	0.014	Fly
defense response to gram negative bacterium	GO:0050829	94	0.014	Fly
eye pigmentation	GO:0048069	43	0.014
cellular response to organic substance	GO:0071310	132	0.014
regulation of cellular ketone metabolic process	GO:0010565	3	0.014
regionalization	GO:0003002	416	0.014
tissue migration	GO:0090130	155	0.014
cellular response to ethanol	GO:0071361	4	0.013
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.013
reproductive behavior	GO:0019098	122	0.013
detection of stimulus	GO:0051606	156	0.013
purine ribonucleoside metabolic process	GO:0046128	127	0.012
programmed cell death	GO:0012501	257	0.012
glycosyl compound metabolic process	GO:1901657	127	0.012
mating behavior	GO:0007617	106	0.012
multi organism reproductive behavior	GO:0044705	121	0.012
lateral inhibition	GO:0046331	206	0.012
purine nucleoside metabolic process	GO:0042278	127	0.012
salivary gland development	GO:0007431	162	0.012
macromolecule catabolic process	GO:0009057	161	0.012
ovarian follicle cell development	GO:0030707	248	0.012
embryonic development via the syncytial blastoderm	GO:0001700	148	0.012
appendage morphogenesis	GO:0035107	397	0.012
autophagic cell death	GO:0048102	83	0.012
response to biotic stimulus	GO:0009607	294	0.012	Fly
purine containing compound catabolic process	GO:0072523	112	0.012
positive regulation of cell communication	GO:0010647	250	0.012
nucleoside catabolic process	GO:0009164	112	0.012
positive regulation of signal transduction	GO:0009967	223	0.011
imaginal disc pattern formation	GO:0007447	91	0.011
amine metabolic process	GO:0009308	12	0.011
exocrine system development	GO:0035272	162	0.011
renal system process	GO:0003014	12	0.011
response to light stimulus	GO:0009416	124	0.011
multicellular organismal reproductive behavior	GO:0033057	110	0.011
purine nucleoside catabolic process	GO:0006152	112	0.011
estrogen metabolic process	GO:0008210	1	0.011
response to lipid	GO:0033993	38	0.011	Rat
chitin based embryonic cuticle biosynthetic process	GO:0008362	16	0.011
glycosyl compound catabolic process	GO:1901658	112	0.011
mesoderm development	GO:0007498	78	0.011
nucleoside phosphate metabolic process	GO:0006753	162	0.011
gland morphogenesis	GO:0022612	145	0.011
positive regulation of signaling	GO:0023056	243	0.011
cell proliferation	GO:0008283	299	0.011
cellular response to lipopolysaccharide	GO:0071222	3	0.010
negative regulation of gene expression	GO:0010629	387	0.010
positive regulation of cell migration	GO:0030335	2	0.010
intracellular signal transduction	GO:0035556	300	0.010
epithelial cell differentiation	GO:0030855	322	0.010
nucleoside metabolic process	GO:0009116	127	0.010
mating	GO:0007618	120	0.010
localization of cell	GO:0051674	257	0.010
eye pigment metabolic process	GO:0042441	33	0.010

Cyp28d1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.165	Human
cardiovascular system disease	DOID:1287	0.165	Human
vascular disease	DOID:178	0.164	Human
hypertension	DOID:10763	0.164	Human
artery disease	DOID:0050828	0.164	Human
essential hypertension	DOID:10825	0.069	Human

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