Drosophila melanogaster

0 known processes

eIF4E-6 (Dmel_CG1442)

CG1442 gene product from transcript CG1442-RA

(Aliases: eIF4E,Dmel\CG1442,CG1442,BcDNA:RH55324)

eIF4E-6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell cell signaling involved in cell fate commitmentGO:00451682100.045
lateral inhibitionGO:00463312060.040
catabolic processGO:00090564090.040
appendage developmentGO:00487364010.035
vesicle mediated transportGO:00161923810.035
regulation of multicellular organismal developmentGO:20000264140.035
cellular catabolic processGO:00442483720.034
appendage morphogenesisGO:00351073970.034
wing disc morphogenesisGO:00074723440.032
imaginal disc derived appendage developmentGO:00487373990.032
post embryonic appendage morphogenesisGO:00351203850.032
positive regulation of response to stimulusGO:00485843230.032
organonitrogen compound metabolic processGO:19015643180.031
sensory perception of chemical stimulusGO:00076061160.031
positive regulation of nitrogen compound metabolic processGO:00511733540.031
endocytosisGO:00068973100.031
transcription from rna polymerase ii promoterGO:00063663680.031
organic substance catabolic processGO:19015753080.030
protein modification processGO:00362114380.029
cellular protein modification processGO:00064644380.029
positive regulation of nucleobase containing compound metabolic processGO:00459353320.029
small molecule metabolic processGO:00442813050.028
detection of chemical stimulus involved in sensory perceptionGO:0050907750.028
imaginal disc derived appendage morphogenesisGO:00351143950.027
imaginal disc derived wing morphogenesisGO:00074763370.027
positive regulation of cellular biosynthetic processGO:00313283160.027
Fly
single organism behaviorGO:00447083910.027
positive regulation of macromolecule metabolic processGO:00106044050.027
Fly
positive regulation of biosynthetic processGO:00098913160.027
Fly
neurological system processGO:00508773580.027
lipid metabolic processGO:00066291210.026
positive regulation of signal transductionGO:00099672230.026
response to external biotic stimulusGO:00432072930.026
macromolecular complex assemblyGO:00650032560.025
organic substance transportGO:00717022570.025
regulation of cell cycleGO:00517262910.025
response to other organismGO:00517072930.024
phagocytosisGO:00069092150.024
ethanolamine containing compound metabolic processGO:004243940.024
response to biotic stimulusGO:00096072940.024
single organism biosynthetic processGO:00447112060.024
taxisGO:00423303040.024
compound eye developmentGO:00487493070.023
regulation of catabolic processGO:00098941700.023
response to lipopolysaccharideGO:003249640.023
positive regulation of cell communicationGO:00106472500.023
regionalizationGO:00030024160.023
chromosome organizationGO:00512763600.023
response to organic substanceGO:00100332840.023
carbohydrate derivative metabolic processGO:19011352170.022
intracellular signal transductionGO:00355563000.022
positive regulation of rna biosynthetic processGO:19026802660.022
deathGO:00162652840.022
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.021
single organism catabolic processGO:00447122280.021
negative regulation of cellular metabolic processGO:00313243820.021
response to abiotic stimulusGO:00096283410.021
regulation of molecular functionGO:00650092170.021
regulation of mitotic cell cycleGO:00073461900.021
sterol homeostasisGO:005509240.021
immune system processGO:00023763470.021
proteolysisGO:00065081920.021
spermatogenesisGO:00072832000.021
Fly
kidney developmentGO:000182230.021
eye developmentGO:00016543230.021
response to bacteriumGO:00096171980.021
positive regulation of signalingGO:00230562430.021
protein localizationGO:00081042840.021
positive regulation of transcription dna templatedGO:00458932660.021
establishment of localization in cellGO:00516494020.021
developmental growthGO:00485892800.021
cellular response to chemical stimulusGO:00708871990.021
cell deathGO:00082192790.021
Fly
defense responseGO:00069523000.020
single organism cellular localizationGO:19025801800.020
protein complex biogenesisGO:00702712010.020
negative regulation of gene expressionGO:00106293870.020
detection of stimulus involved in sensory perceptionGO:0050906920.020
negative regulation of cell communicationGO:00106482230.020
cell proliferationGO:00082832990.020
forebrain developmentGO:003090020.020
regulation of anatomical structure morphogenesisGO:00226032420.020
body morphogenesisGO:001017120.020
endomembrane system organizationGO:00102561190.020
regulation of transcription from rna polymerase ii promoterGO:00063573780.020
compound eye morphogenesisGO:00017452490.020
tissue morphogenesisGO:00487292970.020
regulation of nervous system developmentGO:00519602480.020
regulation of localizationGO:00328792750.019
regulation of cellular ketone metabolic processGO:001056530.019
negative regulation of developmental processGO:00510932010.019
nuclear divisionGO:00002803320.019
organophosphate metabolic processGO:00196371950.019
regulation of response to stressGO:00801342000.019
cell divisionGO:00513012480.019
cellular amine metabolic processGO:0044106120.019
eye morphogenesisGO:00485922600.019
morphogenesis of an epitheliumGO:00020092760.019
carboxylic acid metabolic processGO:0019752920.019
amine metabolic processGO:0009308120.019
regulation of cell differentiationGO:00455953020.019
positive regulation of gene expressionGO:00106282900.019
Fly
organic acid metabolic processGO:00060821030.019
programmed cell deathGO:00125012570.019
Fly
detection of chemical stimulusGO:0009593930.019
positive regulation of macromolecule biosynthetic processGO:00105572830.018
Fly
segmentationGO:00352822070.018
negative regulation of biosynthetic processGO:00098902770.018
axis specificationGO:00097981670.018
negative regulation of rna metabolic processGO:00512532510.018
ras protein signal transductionGO:0007265880.018
camera type eye developmentGO:004301040.018
localization of cellGO:00516742570.018
negative regulation of signalingGO:00230572190.018
defense response to other organismGO:00985422250.018
negative regulation of signal transductionGO:00099682060.018
positive regulation of rna metabolic processGO:00512542710.018
oxoacid metabolic processGO:00434361030.018
negative regulation of cellular biosynthetic processGO:00313272770.018
regulation of sequestering of triglycerideGO:001088930.018
regulation of cellular amine metabolic processGO:003323830.018
cell cycle phase transitionGO:00447701400.018
regulation of catalytic activityGO:00507901850.018
axon developmentGO:00615642970.018
cellular macromolecule localizationGO:00707272200.018
homeostatic processGO:00425921990.018
protein complex assemblyGO:00064612000.017
regulation of cellular amino acid metabolic processGO:000652100.017
phosphorylationGO:00163102940.017
cellular amino acid metabolic processGO:0006520610.017
triglyceride catabolic processGO:001943330.017
regulation of cellular component biogenesisGO:00440872010.017
dorsal ventral axis specificationGO:0009950660.017
defense response to bacteriumGO:00427421780.017
blastoderm segmentationGO:00073501590.017
protein heterooligomerizationGO:005129140.017
aromatic compound catabolic processGO:00194391660.017
adult behaviorGO:00305341370.017
response to oxygen containing compoundGO:19017002000.017
positive regulation of cell motilityGO:200014730.017
negative regulation of nucleic acid templated transcriptionGO:19035072400.017
cholesterol homeostasisGO:004263230.017
embryonic pattern specificationGO:00098801740.017
purine ribonucleotide metabolic processGO:00091501450.017
regulation of protein metabolic processGO:00512462560.017
Fly
epithelial cell differentiationGO:00308553220.017
regulation of intracellular signal transductionGO:19025312360.017
macromolecule catabolic processGO:00090571610.017
negative regulation of response to stimulusGO:00485852580.017
detection of stimulusGO:00516061560.016
developmental maturationGO:00217001720.016
chromatin organizationGO:00063252070.016
connective tissue developmentGO:006144830.016
response to radiationGO:00093141550.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
nucleobase containing small molecule metabolic processGO:00550861740.016
regulation of cellular protein metabolic processGO:00322682430.016
Fly
small gtpase mediated signal transductionGO:0007264880.016
cell motilityGO:00488702510.016
purine containing compound metabolic processGO:00725211550.016
organic cyclic compound catabolic processGO:19013611680.016
neutral lipid biosynthetic processGO:004646020.016
cellular ketone metabolic processGO:0042180240.016
regulation of phosphorus metabolic processGO:00511742100.016
glycerolipid catabolic processGO:004650330.016
hormone catabolic processGO:004244730.016
regulation of cellular catabolic processGO:00313291570.016
organonitrogen compound biosynthetic processGO:19015661170.016
negative regulation of nucleobase containing compound metabolic processGO:00459342610.016
membrane organizationGO:00610241120.016
immune responseGO:00069552460.016
nucleoside phosphate metabolic processGO:00067531620.016
nucleotide metabolic processGO:00091171610.016
response to organophosphorusGO:004668320.015
regulation of cell developmentGO:00602842150.015
cellular response to dna damage stimulusGO:00069742230.015
regulation of cell cycle phase transitionGO:19019871300.015
organelle fissionGO:00482853400.015
negative regulation of multicellular organismal processGO:00512411420.015
telencephalon developmentGO:002153720.015
axonogenesisGO:00074092900.015
rna processingGO:00063961470.015
nucleobase containing compound catabolic processGO:00346551650.015
sensory organ morphogenesisGO:00905962600.015
cellular macromolecule catabolic processGO:00442651360.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
heterocycle catabolic processGO:00467001660.015
dendrite developmentGO:00163582040.015
regulation of transportGO:00510491810.015
compound eye photoreceptor cell differentiationGO:00017511400.015
mitotic cell cycle phase transitionGO:00447721380.015
mitotic nuclear divisionGO:00070672130.015
acylglycerol catabolic processGO:004646430.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
ribonucleotide metabolic processGO:00092591450.015
positive regulation of nucleic acid templated transcriptionGO:19035082660.015
male gamete generationGO:00482322010.015
Fly
intracellular transportGO:00469072280.015
immune response regulating signaling pathwayGO:000276420.015
biological adhesionGO:00226101380.014
multicellular organismal agingGO:00102591400.014
purine nucleotide metabolic processGO:00061631460.014
dendrite morphogenesisGO:00488131990.014
chemotaxisGO:00069352490.014
positive regulation of cell migrationGO:003033520.014
chemosensory behaviorGO:00076351060.014
g protein coupled receptor signaling pathwayGO:00071861360.014
gland developmentGO:00487321910.014
Fly
regulation of cell cycle processGO:00105641810.014
regulation of organelle organizationGO:00330431960.014
regulation of cell deathGO:00109411730.014
hematopoietic progenitor cell differentiationGO:000224410.014
protein transportGO:00150311550.014
single organism intracellular transportGO:19025822070.014
regulation of epithelial cell differentiationGO:003085640.014
triglyceride biosynthetic processGO:001943220.014
chromatin modificationGO:00165681470.014
dna metabolic processGO:00062592270.014
regulation of immune responseGO:00507761180.014
organophosphate catabolic processGO:00464341120.014
establishment of protein localizationGO:00451841630.014
cytoplasmic transportGO:00164821300.014
olfactory behaviorGO:0042048970.014
regulation of multi organism processGO:00439001310.014
organelle assemblyGO:00709251980.014
regulation of programmed cell deathGO:00430671520.014
immune response activating signal transductionGO:000275720.014
androgen metabolic processGO:000820910.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
retina development in camera type eyeGO:006004140.014
cellular nitrogen compound catabolic processGO:00442701650.014
salivary gland developmentGO:00074311620.014
Fly
regulation of immune system processGO:00026821760.014
negative regulation of rna biosynthetic processGO:19026792400.014
cellular protein localizationGO:00346131600.014
intracellular protein transportGO:00068861040.014
regulation of notch signaling pathwayGO:00085931000.014
embryonic morphogenesisGO:00485982060.014
sensory perception of smellGO:0007608800.014
embryonic axis specificationGO:00005781070.014
ribose phosphate metabolic processGO:00196931450.014
negative regulation of cell differentiationGO:00455961430.014
spindle organizationGO:00070512530.013
purine nucleoside triphosphate catabolic processGO:00091461080.013
cellular response to organic substanceGO:00713101320.013
response to copper ionGO:004668840.013
negative regulation of macromolecule biosynthetic processGO:00105582700.013
actin cytoskeleton organizationGO:00300362060.013
purine containing compound catabolic processGO:00725231120.013
cellular response to lipopolysaccharideGO:007122230.013
positive regulation of molecular functionGO:00440931360.013
epithelial cell developmentGO:00020642740.013
organonitrogen compound catabolic processGO:19015651280.013
chromosome segregationGO:00070591570.013
response to nitrogen compoundGO:1901698900.013
lipopolysaccharide mediated signaling pathwayGO:003166310.013
golgi organizationGO:0007030660.013
rna localizationGO:00064031150.013
neuron projection guidanceGO:00974852410.013
axon guidanceGO:00074112330.013
purine ribonucleoside metabolic processGO:00461281270.013
negative regulation of transcription dna templatedGO:00458922370.013
limb developmentGO:006017310.013
positive regulation of phosphate metabolic processGO:00459371390.013
maintenance of locationGO:0051235730.013
central nervous system developmentGO:00074172010.013
developmental programmed cell deathGO:00106231380.013
Fly
gene silencingGO:00164581380.013
cellular macromolecular complex assemblyGO:00346221530.013
actin filament based processGO:00300292200.013
regulation of cellular localizationGO:00603411360.013
nucleoside metabolic processGO:00091161270.013
antimicrobial humoral responseGO:0019730990.013
response to light stimulusGO:00094161240.013
cellular lipid metabolic processGO:0044255830.013
regulation of lipid transportGO:003236830.013
anterior posterior pattern specificationGO:00099521360.013
cellular response to biotic stimulusGO:007121640.013
exocrine system developmentGO:00352721620.013
Fly
autophagyGO:00069141080.013
innate immune responseGO:00450871440.013
defense response to gram negative bacteriumGO:0050829940.013
nucleoside catabolic processGO:00091641120.013
carbohydrate derivative biosynthetic processGO:1901137850.013
ameboidal type cell migrationGO:00016671510.013
purine nucleoside metabolic processGO:00422781270.013
positive regulation of developmental processGO:00510941430.012
protein maturationGO:0051604710.012
negative regulation of mitotic cell cycleGO:00459301090.012
cell adhesionGO:00071551360.012
mesenchymal cell differentiationGO:004876210.012
ribonucleoside metabolic processGO:00091191270.012
purine ribonucleoside catabolic processGO:00461301120.012
cognitionGO:00508901410.012
cell maturationGO:00484691440.012
positive regulation of phosphorus metabolic processGO:00105621390.012
nucleoside triphosphate metabolic processGO:00091411200.012
regulation of apoptotic processGO:00429811300.012
hindbrain developmentGO:003090220.012
peptide metabolic processGO:0006518800.012
regulation of phosphate metabolic processGO:00192202100.012
negative regulation of cell cycle phase transitionGO:19019881030.012
chaeta developmentGO:0022416970.012
negative regulation of cell cycleGO:00457861160.012
nephron developmentGO:007200630.012
notch signaling pathwayGO:00072191200.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
nucleoside phosphate catabolic processGO:19012921100.012
apoptotic processGO:00069151590.012
actin filament organizationGO:00070151260.012
regulation of gene expression epigeneticGO:00400291280.012
single organism membrane organizationGO:0044802930.012
growthGO:00400073590.012
chemical homeostasisGO:0048878920.012
synaptic transmissionGO:00072682880.012
positive regulation of catalytic activityGO:00430851180.012
xenobiotic catabolic processGO:004217810.012
positive regulation of multicellular organismal processGO:00512401430.012
estrogen metabolic processGO:000821010.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
mesenchymal cell developmentGO:001403110.012
response to endogenous stimulusGO:00097191190.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
steroid catabolic processGO:000670610.012
rhythmic processGO:00485111060.012
regulation of epithelial cell proliferationGO:005067840.012
photoreceptor cell developmentGO:0042461960.012
purine nucleotide catabolic processGO:00061951090.012
nucleoside triphosphate catabolic processGO:00091431080.012
phosphatidic acid metabolic processGO:004647310.012
mitotic spindle organizationGO:00070522200.012
somatic muscle developmentGO:0007525660.012
cellular response to molecule of bacterial originGO:007121930.012
negative regulation of cellular component organizationGO:00511291080.012
negative regulation of nervous system developmentGO:0051961920.012
limb morphogenesisGO:003510810.012
cellular protein catabolic processGO:0044257830.012
ribonucleotide catabolic processGO:00092611090.012
regulation of response to external stimulusGO:00321011150.011
phospholipid homeostasisGO:005509110.011
regulation of defense responseGO:00313471020.011
synapse organizationGO:00508081960.011
protein modification by small protein conjugation or removalGO:00706471060.011
anterior posterior axis specification embryoGO:00085951030.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
anion homeostasisGO:005508130.011
response to glucoseGO:000974920.011
glycosyl compound metabolic processGO:19016571270.011
protein phosphorylationGO:00064681690.011
glycosyl compound catabolic processGO:19016581120.011
regulation of growthGO:00400082330.011
positive regulation of lipid storageGO:001088440.011
camera type eye morphogenesisGO:004859320.011
response to hexoseGO:000974630.011
negative regulation of cellular protein metabolic processGO:0032269850.011
tissue deathGO:00162711020.011
Fly
cell recognitionGO:00080371020.011
ion transportGO:00068111450.011
salivary gland morphogenesisGO:00074351450.011
Fly
regulation of neuron differentiationGO:00456641030.011
embryonic development via the syncytial blastodermGO:00017001480.011
regulation of anatomical structure sizeGO:00900661630.011
cellular response to radiationGO:0071478520.011
eye photoreceptor cell differentiationGO:00017541450.011
immune effector processGO:0002252980.011
purine ribonucleotide catabolic processGO:00091541090.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
regulation of developmental growthGO:00486381740.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
salivary gland histolysisGO:0035070880.011
Fly
determination of adult lifespanGO:00083401370.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
positive regulation of transportGO:0051050920.011
nucleotide catabolic processGO:00091661090.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
spinal cord developmentGO:002151010.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
positive regulation of cellular catabolic processGO:0031331950.011
locomotory behaviorGO:00076261760.011
mrna metabolic processGO:00160711240.011
ribonucleoside catabolic processGO:00424541120.011
dorsal ventral pattern formationGO:00099531330.011
negative regulation of cell cycle processGO:00109481090.011
positive regulation of intracellular signal transductionGO:19025331160.011
sensory perceptionGO:00076001960.011
protein processingGO:0016485680.011
monocarboxylic acid transportGO:001571830.011
cellular amide metabolic processGO:0043603800.011
regulation of cellular response to stressGO:0080135890.011
tripartite regional subdivisionGO:00073511030.011
regulation of ras protein signal transductionGO:0046578930.011
posttranscriptional regulation of gene expressionGO:00106081450.011
Fly
open tracheal system developmentGO:00074242040.011
alditol phosphate metabolic processGO:005264620.011
cellular homeostasisGO:0019725800.011
purine nucleoside catabolic processGO:00061521120.010
nephron morphogenesisGO:007202830.010
synaptic growth at neuromuscular junctionGO:00511241190.010
anatomical structure homeostasisGO:0060249970.010
synapse assemblyGO:00074161430.010
wnt signaling pathwayGO:0016055980.010
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.010
nephron epithelium developmentGO:007200930.010
positive regulation of catabolic processGO:00098961050.010
cell migrationGO:00164772380.010
chromatin remodelingGO:0006338720.010
establishment or maintenance of cell polarityGO:00071631670.010
neurotransmitter metabolic processGO:004213320.010
rna splicingGO:0008380830.010
mrna processingGO:00063971040.010
humoral immune responseGO:00069591170.010
agingGO:00075681430.010
memoryGO:0007613940.010
photoreceptor cell differentiationGO:00465301700.010
response to monosaccharideGO:003428440.010
kidney epithelium developmentGO:007207330.010
rhythmic behaviorGO:0007622760.010
protein catabolic processGO:00301631010.010
regulation of innate immune responseGO:0045088710.010
compound eye photoreceptor developmentGO:0042051780.010
columnar cuboidal epithelial cell differentiationGO:00020652560.010
mapk cascadeGO:00001651070.010
mitotic cell cycle checkpointGO:0007093880.010

eIF4E-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
nervous system diseaseDOID:86300.022
disease of metabolismDOID:001466700.017
sensory system diseaseDOID:005015500.014
glucose metabolism diseaseDOID:419400.013
diabetes mellitusDOID:935100.013
type 2 diabetes mellitusDOID:935200.013
acquired metabolic diseaseDOID:006015800.013
carbohydrate metabolism diseaseDOID:005001300.013
inherited metabolic disorderDOID:65500.013
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013
familial hypertriglyceridemiaDOID:005052700.012
lipid metabolism disorderDOID:314600.012
cardiovascular system diseaseDOID:128700.012
musculoskeletal system diseaseDOID:1700.011
familial hyperlipidemiaDOID:116800.011
familial combined hyperlipidemiaDOID:1380900.011