IMP: Integrative Multi-species Prediction

Drosophila melanogaster

19 known processes

zf30C (Dmel_CG3998)

Zinc finger protein 30C

(Aliases: l(2)k02506,clone 1.52,anon-EST:Liang-1.52,CG3998,Zf30c,Dmel\CG3998,Zn30C,zf30c)

Entrez: 34292
FLYBASE: FBgn0022720
UniProtKB: Q9VL91

Process Predictions
Disease Predictions

zf30C biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.694
negative regulation of transcription dna templated	GO:0045892	237	0.616
chromatin organization	GO:0006325	207	0.544
chromatin modification	GO:0016568	147	0.539
negative regulation of rna metabolic process	GO:0051253	251	0.464
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.425
negative regulation of cellular biosynthetic process	GO:0031327	277	0.403
embryo development ending in birth or egg hatching	GO:0009792	152	0.400
negative regulation of gene expression	GO:0010629	387	0.338
body morphogenesis	GO:0010171	2	0.306
eye development	GO:0001654	323	0.270
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.269
rna processing	GO:0006396	147	0.239
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.214
small molecule metabolic process	GO:0044281	305	0.207
chromosome organization	GO:0051276	360	0.205
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.197
imaginal disc derived wing vein specification	GO:0007474	48	0.156
appendage morphogenesis	GO:0035107	397	0.154
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.143
oocyte dorsal ventral axis specification	GO:0007310	34	0.129
rna splicing via transesterification reactions	GO:0000375	73	0.128
negative regulation of biosynthetic process	GO:0009890	277	0.125
organic acid metabolic process	GO:0006082	103	0.102
organelle fission	GO:0048285	340	0.100
negative regulation of developmental process	GO:0051093	201	0.097
rna splicing	GO:0008380	83	0.095
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.091
stem cell differentiation	GO:0048863	117	0.087
transcription from rna polymerase ii promoter	GO:0006366	368	0.087
covalent chromatin modification	GO:0016569	106	0.083
positive regulation of cellular biosynthetic process	GO:0031328	316	0.079
vesicle mediated transport	GO:0016192	381	0.079
central nervous system development	GO:0007417	201	0.078
peptidyl amino acid modification	GO:0018193	105	0.076
cellular protein modification process	GO:0006464	438	0.075
spindle organization	GO:0007051	253	0.073
regionalization	GO:0003002	416	0.072
tube development	GO:0035295	244	0.069
negative regulation of cell differentiation	GO:0045596	143	0.068
wing disc morphogenesis	GO:0007472	344	0.067
appendage development	GO:0048736	401	0.065
oxoacid metabolic process	GO:0043436	103	0.064
mrna metabolic process	GO:0016071	124	0.063
chromatin remodeling	GO:0006338	72	0.063
tissue morphogenesis	GO:0048729	297	0.060
sensory organ morphogenesis	GO:0090596	260	0.057
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.057
eye morphogenesis	GO:0048592	260	0.056
gene silencing	GO:0016458	138	0.056
negative regulation of cellular metabolic process	GO:0031324	382	0.054
negative regulation of rna biosynthetic process	GO:1902679	240	0.054
segmentation	GO:0035282	207	0.054
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.054
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.051
regulation of mrna processing	GO:0050684	71	0.050
stem cell maintenance	GO:0019827	67	0.045
compound eye development	GO:0048749	307	0.044
regulation of cellular amino acid metabolic process	GO:0006521	0	0.041
reproductive system development	GO:0061458	74	0.041
positive regulation of rna biosynthetic process	GO:1902680	266	0.038
regulation of mrna splicing via spliceosome	GO:0048024	64	0.038
positive regulation of cell communication	GO:0010647	250	0.037
regulation of cellular ketone metabolic process	GO:0010565	3	0.037
stem cell development	GO:0048864	79	0.036
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.036
muscle structure development	GO:0061061	224	0.036
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.035
histone modification	GO:0016570	106	0.034
gonad development	GO:0008406	50	0.034
protein modification process	GO:0036211	438	0.034
mitotic nuclear division	GO:0007067	213	0.034
regulation of mrna metabolic process	GO:1903311	72	0.033
chemotaxis	GO:0006935	249	0.032
regulation of cell differentiation	GO:0045595	302	0.032
positive regulation of transcription dna templated	GO:0045893	266	0.032
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.032
imaginal disc derived appendage development	GO:0048737	399	0.032
apoptotic process	GO:0006915	159	0.031
nuclear division	GO:0000280	332	0.028
regulation of protein metabolic process	GO:0051246	256	0.028
sex differentiation	GO:0007548	81	0.027
negative regulation of signaling	GO:0023057	219	0.027
dendrite development	GO:0016358	204	0.027
positive regulation of signal transduction	GO:0009967	223	0.026
organic substance transport	GO:0071702	257	0.026
axon guidance	GO:0007411	233	0.025
axon development	GO:0061564	297	0.025
ribonucleoside catabolic process	GO:0042454	112	0.024
cellular amine metabolic process	GO:0044106	12	0.023
camera type eye development	GO:0043010	4	0.023
morphogenesis of an epithelium	GO:0002009	276	0.023
small gtpase mediated signal transduction	GO:0007264	88	0.023
positive regulation of neuron projection regeneration	GO:0070572	3	0.022
ras protein signal transduction	GO:0007265	88	0.022
regulation of catalytic activity	GO:0050790	185	0.022
negative regulation of multicellular organismal process	GO:0051241	142	0.021
post embryonic appendage morphogenesis	GO:0035120	385	0.021
carbohydrate derivative metabolic process	GO:1901135	217	0.021
head development	GO:0060322	135	0.019
cellular response to organic substance	GO:0071310	132	0.019
negative regulation of cell cycle process	GO:0010948	109	0.019
oocyte differentiation	GO:0009994	145	0.019
brain development	GO:0007420	120	0.019
spindle assembly	GO:0051225	80	0.019
hematopoietic stem cell differentiation	GO:0060218	1	0.019
positive regulation of biosynthetic process	GO:0009891	316	0.019
negative regulation of signal transduction	GO:0009968	206	0.019
nucleosome organization	GO:0034728	59	0.019
formation of a compartment boundary	GO:0060288	4	0.018
negative regulation of gene expression epigenetic	GO:0045814	77	0.018
reproductive structure development	GO:0048608	74	0.018
connective tissue development	GO:0061448	3	0.018
tube morphogenesis	GO:0035239	191	0.018
cellular macromolecule localization	GO:0070727	220	0.018
mrna splicing via spliceosome	GO:0000398	73	0.017
nucleoside phosphate metabolic process	GO:0006753	162	0.017
imaginal disc derived wing morphogenesis	GO:0007476	337	0.017
axis specification	GO:0009798	167	0.017
regulation of cell cycle process	GO:0010564	181	0.017
regulation of chromatin modification	GO:1903308	28	0.017
negative regulation of cell proliferation	GO:0008285	69	0.016
larval development	GO:0002164	104	0.016
cell motility	GO:0048870	251	0.016
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.016
circulatory system development	GO:0072359	82	0.016
cellular ketone metabolic process	GO:0042180	24	0.015
negative regulation of transcription factor import into nucleus	GO:0042992	4	0.015
growth	GO:0040007	359	0.015
nuclear transport	GO:0051169	72	0.015
mitochondrial membrane organization	GO:0007006	3	0.015
ovulation cycle	GO:0042698	1	0.015
digestive tract development	GO:0048565	149	0.014
compound eye photoreceptor cell differentiation	GO:0001751	140	0.014
regulation of neurogenesis	GO:0050767	158	0.014
dorsal ventral pattern formation	GO:0009953	133	0.014
negative regulation of growth	GO:0045926	84	0.014
multicellular organism growth	GO:0035264	46	0.014
germ line stem cell maintenance	GO:0030718	50	0.014
neuroblast proliferation	GO:0007405	74	0.014
spermatogenesis	GO:0007283	200	0.013
death	GO:0016265	284	0.013
regulation of cellular amine metabolic process	GO:0033238	3	0.013
organonitrogen compound metabolic process	GO:1901564	318	0.013
nitrogen compound transport	GO:0071705	85	0.012
positive regulation of macromolecule metabolic process	GO:0010604	405	0.012
asymmetric neuroblast division resulting in ganglion mother cell formation	GO:0055060	2	0.012
positive regulation of gene expression	GO:0010628	290	0.012
organic substance catabolic process	GO:1901575	308	0.012
localization of cell	GO:0051674	257	0.012
negative regulation of response to stimulus	GO:0048585	258	0.012
positive regulation of signaling	GO:0023056	243	0.012
gastrulation	GO:0007369	70	0.012
cellular response to dna damage stimulus	GO:0006974	223	0.012
nucleobase containing compound transport	GO:0015931	56	0.012
dorsal vessel heart proper cell fate commitment	GO:0035053	2	0.012
regulation of programmed cell death	GO:0043067	152	0.012
cellular response to nutrient	GO:0031670	1	0.012
embryonic pattern specification	GO:0009880	174	0.012
septin ring organization	GO:0031106	1	0.012
male gamete generation	GO:0048232	201	0.011
endocytosis	GO:0006897	310	0.011
regulation of nervous system development	GO:0051960	248	0.011
nucleocytoplasmic transport	GO:0006913	72	0.011
epithelial cell development	GO:0002064	274	0.011
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.011
positive regulation of cellular amine metabolic process	GO:0033240	0	0.011
establishment of rna localization	GO:0051236	47	0.011
regulation of calcium ion transmembrane transport	GO:1903169	2	0.011
regulation of hemocyte proliferation	GO:0035206	37	0.011
organophosphate metabolic process	GO:0019637	195	0.010
regulation of gene expression epigenetic	GO:0040029	128	0.010
icosanoid biosynthetic process	GO:0046456	1	0.010
programmed cell death	GO:0012501	257	0.010
meiotic cell cycle	GO:0051321	171	0.010

zf30C disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.019
organ system cancer	DOID:0050686	0.018
cancer	DOID:162	0.018
disease of cellular proliferation	DOID:14566	0.018
chromosomal disease	DOID:0080014	0.013
respiratory system cancer	DOID:0050615	0.010

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