Drosophila melanogaster

15 known processes

Tom40 (Dmel_CG12157)

Translocase of outer membrane 40

(Aliases: dtom40,ms(1)15,Dmel\CG12157,CG12157,l(1)G0216,tom40,ms15,mit)

Tom40 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
imaginal disc derived appendage morphogenesisGO:00351143950.148
defense response to bacteriumGO:00427421780.085
catabolic processGO:00090564090.082
appendage developmentGO:00487364010.079
modification dependent macromolecule catabolic processGO:0043632790.062
ubiquitin dependent protein catabolic processGO:0006511780.061
defense responseGO:00069523000.061
protein catabolic processGO:00301631010.061
small molecule metabolic processGO:00442813050.060
cellular macromolecule catabolic processGO:00442651360.058
protein complex biogenesisGO:00702712010.056
establishment of localization in cellGO:00516494020.054
Rat
cellular protein modification processGO:00064644380.053
positive regulation of macromolecule biosynthetic processGO:00105572830.052
organelle fissionGO:00482853400.051
appendage morphogenesisGO:00351073970.051
cellular amine metabolic processGO:0044106120.051
organonitrogen compound metabolic processGO:19015643180.049
macromolecule catabolic processGO:00090571610.049
immune responseGO:00069552460.049
modification dependent protein catabolic processGO:0019941780.047
regulation of defense responseGO:00313471020.047
wing disc morphogenesisGO:00074723440.047
regulation of cellular amine metabolic processGO:003323830.046
cellular ketone metabolic processGO:0042180240.046
intracellular signal transductionGO:00355563000.045
post embryonic appendage morphogenesisGO:00351203850.045
growthGO:00400073590.045
imaginal disc derived appendage developmentGO:00487373990.044
positive regulation of macromolecule metabolic processGO:00106044050.042
mitotic nuclear divisionGO:00070672130.041
positive regulation of rna biosynthetic processGO:19026802660.041
organonitrogen compound biosynthetic processGO:19015661170.041
carboxylic acid metabolic processGO:0019752920.040
innate immune responseGO:00450871440.040
nuclear divisionGO:00002803320.039
proteolysisGO:00065081920.039
positive regulation of gene expressionGO:00106282900.039
cell deathGO:00082192790.039
cellular protein catabolic processGO:0044257830.038
cellular amino acid metabolic processGO:0006520610.037
positive regulation of nucleic acid templated transcriptionGO:19035082660.037
oxoacid metabolic processGO:00434361030.037
establishment of protein localizationGO:00451841630.036
Rat
single organism intracellular transportGO:19025822070.036
Rat
regulation of cellular protein metabolic processGO:00322682430.036
protein complex assemblyGO:00064612000.035
imaginal disc derived wing morphogenesisGO:00074763370.035
organic substance catabolic processGO:19015753080.035
vesicle mediated transportGO:00161923810.033
cell cycle phase transitionGO:00447701400.033
positive regulation of response to stimulusGO:00485843230.033
biological adhesionGO:00226101380.033
salivary gland developmentGO:00074311620.033
regulation of cellular ketone metabolic processGO:001056530.033
proteolysis involved in cellular protein catabolic processGO:0051603830.033
deathGO:00162652840.032
exocrine system developmentGO:00352721620.032
negative regulation of response to stimulusGO:00485852580.032
protein modification processGO:00362114380.032
cellular macromolecule localizationGO:00707272200.031
Rat
phosphorylationGO:00163102940.031
developmental growthGO:00485892800.031
positive regulation of nitrogen compound metabolic processGO:00511733540.030
positive regulation of defense responseGO:0031349590.030
immune system processGO:00023763470.030
positive regulation of cellular biosynthetic processGO:00313283160.029
positive regulation of signalingGO:00230562430.029
endomembrane system organizationGO:00102561190.029
regulation of cellular amino acid metabolic processGO:000652100.029
regulation of immune responseGO:00507761180.028
endocytosisGO:00068973100.028
positive regulation of nucleobase containing compound metabolic processGO:00459353320.028
regulation of mitotic cell cycle phase transitionGO:19019901300.028
response to other organismGO:00517072930.028
intracellular transportGO:00469072280.027
Rat
organic acid metabolic processGO:00060821030.027
establishment of organelle localizationGO:00516561220.026
regulation of localizationGO:00328792750.026
organic substance transportGO:00717022570.026
Rat
amine metabolic processGO:0009308120.026
establishment or maintenance of cell polarityGO:00071631670.026
cellular catabolic processGO:00442483720.026
negative regulation of gene expressionGO:00106293870.026
gland morphogenesisGO:00226121450.026
positive regulation of rna metabolic processGO:00512542710.026
chromosome organizationGO:00512763600.025
salivary gland morphogenesisGO:00074351450.025
regulation of cell cycle phase transitionGO:19019871300.024
defense response to other organismGO:00985422250.024
negative regulation of cellular metabolic processGO:00313243820.024
regulation of anatomical structure morphogenesisGO:00226032420.024
muscle structure developmentGO:00610612240.024
neurological system processGO:00508773580.024
regulation of immune system processGO:00026821760.023
regulation of multicellular organismal developmentGO:20000264140.023
developmental maturationGO:00217001720.023
histone acetylationGO:0016573380.022
regulation of catabolic processGO:00098941700.022
positive regulation of transcription dna templatedGO:00458932660.022
positive regulation of cell communicationGO:00106472500.022
anterior posterior axis specificationGO:00099481090.022
regulation of innate immune responseGO:0045088710.022
developmental programmed cell deathGO:00106231380.022
regulation of proteolysisGO:0030162870.021
mapk cascadeGO:00001651070.021
posttranscriptional regulation of gene expressionGO:00106081450.021
mitotic cell cycle phase transitionGO:00447721380.021
positive regulation of immune responseGO:0050778630.021
regulation of transportGO:00510491810.021
response to bacteriumGO:00096171980.021
negative regulation of signal transductionGO:00099682060.021
homeostatic processGO:00425921990.021
regulation of phosphate metabolic processGO:00192202100.020
body morphogenesisGO:001017120.020
protein acylationGO:0043543420.020
somatic muscle developmentGO:0007525660.020
rrna processingGO:000636430.019
negative regulation of mitotic cell cycle phase transitionGO:19019911030.019
protein phosphorylationGO:00064681690.019
positive regulation of developmental processGO:00510941430.019
forebrain developmentGO:003090020.019
developmental pigmentationGO:0048066680.019
regulation of protein metabolic processGO:00512462560.019
regulation of mapk cascadeGO:0043408920.019
camera type eye developmentGO:004301040.019
regulation of cell cycleGO:00517262910.018
phagocytosisGO:00069092150.018
mitotic g2 dna damage checkpointGO:0007095690.018
protein dna complex subunit organizationGO:0071824860.018
autophagyGO:00069141080.018
regulation of cell differentiationGO:00455953020.018
response to external biotic stimulusGO:00432072930.018
chromatin remodelingGO:0006338720.018
regulation of phosphorus metabolic processGO:00511742100.018
positive regulation of signal transductionGO:00099672230.017
compound eye developmentGO:00487493070.017
single organism biosynthetic processGO:00447112060.017
cell adhesionGO:00071551360.017
single organism catabolic processGO:00447122280.017
defense response to gram negative bacteriumGO:0050829940.017
oocyte axis specificationGO:00073091080.017
cell divisionGO:00513012480.017
embryonic pattern specificationGO:00098801740.017
cellular homeostasisGO:0019725800.016
protein transportGO:00150311550.016
Rat
regulation of response to stressGO:00801342000.016
positive regulation of biosynthetic processGO:00098913160.016
response to biotic stimulusGO:00096072940.016
instar larval developmentGO:0002168550.016
macromolecular complex assemblyGO:00650032560.016
eye developmentGO:00016543230.016
connective tissue developmentGO:006144830.016
regulation of cell deathGO:00109411730.016
protein modification by small protein conjugation or removalGO:00706471060.016
head developmentGO:00603221350.015
regulation of protein catabolic processGO:0042176550.015
muscle cell differentiationGO:00426921030.015
organelle assemblyGO:00709251980.015
striated muscle myosin thick filament assemblyGO:007168830.015
pigmentationGO:0043473750.015
regulation of cellular catabolic processGO:00313291570.015
carbohydrate derivative metabolic processGO:19011352170.015
cell cycle checkpointGO:0000075950.015
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.015
lipid metabolic processGO:00066291210.015
aromatic compound catabolic processGO:00194391660.015
segmentationGO:00352822070.015
regulation of mitotic cell cycleGO:00073461900.014
muscle attachmentGO:0016203360.014
single organism cell adhesionGO:0098602470.014
protein modification by small protein conjugationGO:0032446790.014
morphogenesis of follicular epitheliumGO:0016333360.014
cellular protein complex assemblyGO:0043623710.014
axis specificationGO:00097981670.014
programmed cell deathGO:00125012570.014
regulation of catalytic activityGO:00507901850.014
protein localizationGO:00081042840.014
Rat
embryonic axis specificationGO:00005781070.014
stress activated protein kinase signaling cascadeGO:0031098550.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.014
morphogenesis of an epitheliumGO:00020092760.014
regulation of epithelial cell proliferationGO:005067840.014
positive regulation of transportGO:0051050920.014
epithelial cell differentiationGO:00308553220.014
dna integrity checkpointGO:0031570810.014
negative regulation of signalingGO:00230572190.014
cellular component assembly involved in morphogenesisGO:00109271510.014
dna metabolic processGO:00062592270.013
cellular response to dna damage stimulusGO:00069742230.013
regionalizationGO:00030024160.013
sister chromatid segregationGO:0000819920.013
regulation of cellular protein catabolic processGO:1903362440.013
localization of cellGO:00516742570.013
cell agingGO:000756920.013
regulation of developmental growthGO:00486381740.013
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.013
autophagic cell deathGO:0048102830.013
cellular nitrogen compound catabolic processGO:00442701650.013
regulation of cellular localizationGO:00603411360.013
proteasomal protein catabolic processGO:0010498590.013
spindle organizationGO:00070512530.013
cognitionGO:00508901410.013
histolysisGO:00075591020.013
negative regulation of cellular catabolic processGO:0031330340.013
cellular response to chemical stimulusGO:00708871990.013
regulation of cell cycle processGO:00105641810.013
negative regulation of cell cycle phase transitionGO:19019881030.013
positive regulation of multicellular organismal processGO:00512401430.013
salivary gland cell autophagic cell deathGO:0035071830.012
cell proliferationGO:00082832990.012
negative regulation of protein metabolic processGO:0051248850.012
dna damage checkpointGO:0000077780.012
regulation of intracellular transportGO:0032386640.012
epithelial cell developmentGO:00020642740.012
cell projection assemblyGO:0030031940.012
anterior posterior pattern specificationGO:00099521360.012
compound eye morphogenesisGO:00017452490.012
memoryGO:0007613940.012
internal peptidyl lysine acetylationGO:0018393380.012
response to abiotic stimulusGO:00096283410.012
single organismal cell cell adhesionGO:0016337450.012
negative regulation of mitotic cell cycleGO:00459301090.012
meiotic cell cycleGO:00513211710.012
negative regulation of cell communicationGO:00106482230.012
tissue deathGO:00162711020.012
immune response regulating signaling pathwayGO:000276420.012
positive regulation of immune system processGO:0002684680.012
nitrogen compound transportGO:0071705850.012
microtubule cytoskeleton organization involved in mitosisGO:1902850520.012
regulation of cell projection organizationGO:0031344920.012
organelle localizationGO:00516401480.012
stress activated mapk cascadeGO:0051403520.012
positive regulation of response to external stimulusGO:0032103440.012
positive regulation of catabolic processGO:00098961050.012
locomotory behaviorGO:00076261760.012
pigment metabolic processGO:0042440840.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
chromatin modificationGO:00165681470.012
anterior posterior axis specification embryoGO:00085951030.012
apoptotic processGO:00069151590.012
cell motilityGO:00488702510.012
actin cytoskeleton organizationGO:00300362060.012
tripartite regional subdivisionGO:00073511030.012
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.011
spindle assembly involved in mitosisGO:0090307500.011
extrinsic apoptotic signaling pathwayGO:009719110.011
nucleobase containing compound catabolic processGO:00346551650.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
chaeta developmentGO:0022416970.011
pole plasm assemblyGO:0007315610.011
adult behaviorGO:00305341370.011
organic cyclic compound catabolic processGO:19013611680.011
cellular protein localizationGO:00346131600.011
Rat
chemotaxisGO:00069352490.011
negative regulation of neuron deathGO:1901215180.011
regulation of molecular functionGO:00650092170.011
embryo development ending in birth or egg hatchingGO:00097921520.011
cell growthGO:00160491080.011
axonogenesisGO:00074092900.011
leg disc developmentGO:0035218920.011
telencephalon developmentGO:002153720.011
oocyte constructionGO:00073081120.011
transcription from rna polymerase ii promoterGO:00063663680.011
male gamete generationGO:00482322010.011
protein ubiquitinationGO:0016567700.011
cytoplasmic transportGO:00164821300.011
Rat
positive regulation of cellular catabolic processGO:0031331950.011
oocyte anterior posterior axis specificationGO:0007314720.011
single organism behaviorGO:00447083910.011
organophosphate metabolic processGO:00196371950.011
negative regulation of cell cycle processGO:00109481090.011
blastoderm segmentationGO:00073501590.011
nucleoside catabolic processGO:00091641120.011
chromosome segregationGO:00070591570.011
notch signaling pathwayGO:00072191200.011
ion transportGO:00068111450.011
single fertilizationGO:0007338240.010
response to lipopolysaccharideGO:003249640.010
positive regulation of molecular functionGO:00440931360.010
kidney developmentGO:000182230.010
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.010
regulation of neuron differentiationGO:00456641030.010
heterocycle catabolic processGO:00467001660.010
neuron deathGO:0070997270.010
salivary gland histolysisGO:0035070880.010
signal transduction by phosphorylationGO:00230141070.010

Tom40 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
disease of cellular proliferationDOID:1456600.019
organ system cancerDOID:005068600.019
cancerDOID:16200.019
nervous system diseaseDOID:86300.013