IMP: Integrative Multi-species Prediction

Drosophila melanogaster

112 known processes

beta-Spec (Dmel_CG5870)

beta Spectrin

(Aliases: b-Spec,Dmel\CG5870,i6,Specbeta,i168,l(1)G0198,Spec-beta,betaspec,kus,l(1)G0074,betaSpec,beta,anon-EST:fe1B3,SPEC8,b spectrin,beta-spec,Spec,CG5870,l(1)G0108)

FLYBASE: FBgn0250788
Entrez: 32746
UniProtKB: M9PF16
UniProtKB: M9PHG4
UniProtKB: Q00963

Process Predictions
Disease Predictions

beta-Spec biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
axon guidance	GO:0007411	233	0.996
neuromuscular junction development	GO:0007528	149	0.987
vesicle localization	GO:0051648	55	0.983
synaptic growth at neuromuscular junction	GO:0051124	119	0.980
synapse assembly	GO:0007416	143	0.967
neuron projection guidance	GO:0097485	241	0.939
organelle localization	GO:0051640	148	0.931
axon midline choice point recognition	GO:0016199	26	0.925
establishment of organelle localization	GO:0051656	122	0.901
g protein coupled receptor signaling pathway	GO:0007186	136	0.895
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.894
chemotaxis	GO:0006935	249	0.882
synapse organization	GO:0050808	196	0.879
axon development	GO:0061564	297	0.866
synaptic transmission	GO:0007268	288	0.843
axonogenesis	GO:0007409	290	0.838
protein localization	GO:0008104	284	0.825
regulation of synapse assembly	GO:0051963	94	0.821
membrane organization	GO:0061024	112	0.779
regulation of growth	GO:0040008	233	0.753
cellular component disassembly	GO:0022411	46	0.752
actin filament based process	GO:0030029	220	0.732
protein complex disassembly	GO:0043241	36	0.717
taxis	GO:0042330	304	0.686
vesicle mediated transport	GO:0016192	381	0.667
sensory organ morphogenesis	GO:0090596	260	0.665
establishment of vesicle localization	GO:0051650	51	0.658
catabolic process	GO:0009056	409	0.652
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.652
positive regulation of developmental process	GO:0051094	143	0.649
axon choice point recognition	GO:0016198	26	0.642
macromolecular complex disassembly	GO:0032984	37	0.602
developmental growth	GO:0048589	280	0.571
regulation of microtubule depolymerization	GO:0031114	24	0.568
endocytosis	GO:0006897	310	0.564
tube development	GO:0035295	244	0.563
maintenance of presynaptic active zone structure	GO:0048790	8	0.524
growth	GO:0040007	359	0.515
neuroblast division	GO:0055057	35	0.499
stem cell differentiation	GO:0048863	117	0.467
regulation of cellular component biogenesis	GO:0044087	201	0.460
establishment of synaptic vesicle localization	GO:0097480	50	0.438
synaptic vesicle transport	GO:0048489	50	0.437
synaptic vesicle recycling	GO:0036465	28	0.433
nucleoside catabolic process	GO:0009164	112	0.422
cellular protein complex assembly	GO:0043623	71	0.411
regulation of cell death	GO:0010941	173	0.397
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.394
cell maturation	GO:0048469	144	0.393
cell motility	GO:0048870	251	0.392
positive regulation of cellular component organization	GO:0051130	156	0.387
actin cytoskeleton organization	GO:0030036	206	0.377
body morphogenesis	GO:0010171	2	0.375
germ line cyst formation	GO:0048134	44	0.369
cell migration	GO:0016477	238	0.367
establishment of localization in cell	GO:0051649	402	0.361
tissue morphogenesis	GO:0048729	297	0.359
brain development	GO:0007420	120	0.353
cellular macromolecule localization	GO:0070727	220	0.350
multi organism behavior	GO:0051705	175	0.344
regulation of cytoskeleton organization	GO:0051493	89	0.342
oocyte development	GO:0048599	124	0.337
negative regulation of protein depolymerization	GO:1901880	23	0.333
glial cell development	GO:0021782	27	0.333
digestive tract morphogenesis	GO:0048546	127	0.316
synaptic vesicle endocytosis	GO:0048488	28	0.315
cell projection assembly	GO:0030031	94	0.314
dendrite development	GO:0016358	204	0.309
regulation of neurotransmitter levels	GO:0001505	38	0.308
small molecule metabolic process	GO:0044281	305	0.305
negative regulation of biosynthetic process	GO:0009890	277	0.299
epithelial cell development	GO:0002064	274	0.291
larval development	GO:0002164	104	0.290
regulation of nervous system development	GO:0051960	248	0.289
regulation of epithelial cell proliferation	GO:0050678	4	0.284
embryo development ending in birth or egg hatching	GO:0009792	152	0.273
embryonic morphogenesis	GO:0048598	206	0.270
neurotransmitter transport	GO:0006836	37	0.268
eye morphogenesis	GO:0048592	260	0.268
neurotransmitter secretion	GO:0007269	35	0.267
oocyte anterior posterior axis specification	GO:0007314	72	0.265
regulation of localization	GO:0032879	275	0.257
locomotory behavior	GO:0007626	176	0.250
cortical actin cytoskeleton organization	GO:0030866	24	0.247
negative regulation of hormone biosynthetic process	GO:0032353	1	0.243
negative regulation of cell communication	GO:0010648	223	0.238
regulation of synapse organization	GO:0050807	110	0.236
multicellular organismal reproductive behavior	GO:0033057	110	0.234
spermatogenesis	GO:0007283	200	0.234
apoptotic cell clearance	GO:0043277	14	0.232
tube morphogenesis	GO:0035239	191	0.220
establishment of spindle orientation	GO:0051294	18	0.218
organonitrogen compound metabolic process	GO:1901564	318	0.217
transition metal ion homeostasis	GO:0055076	17	0.216
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.214
ameboidal type cell migration	GO:0001667	151	0.210
regulation of vesicle mediated transport	GO:0060627	59	0.208
cellular macromolecular complex assembly	GO:0034622	153	0.206
forebrain development	GO:0030900	2	0.205
regulation of organelle organization	GO:0033043	196	0.204
digestive tract development	GO:0048565	149	0.202
border follicle cell migration	GO:0007298	113	0.201
asymmetric cell division	GO:0008356	37	0.199
branching morphogenesis of an epithelial tube	GO:0048754	45	0.199
establishment or maintenance of cell polarity	GO:0007163	167	0.188
regulation of synapse structure and activity	GO:0050803	128	0.185
protein complex assembly	GO:0006461	200	0.177
female germ line cyst formation	GO:0048135	42	0.176
macromolecular complex assembly	GO:0065003	256	0.175
negative regulation of organelle organization	GO:0010639	56	0.174
post embryonic appendage morphogenesis	GO:0035120	385	0.174
positive regulation of macromolecule metabolic process	GO:0010604	405	0.171
regulation of dendrite morphogenesis	GO:0048814	28	0.170
nucleobase containing small molecule metabolic process	GO:0055086	174	0.169
learning or memory	GO:0007611	141	0.168
columnar cuboidal epithelial cell development	GO:0002066	249	0.168
transcription from rna polymerase ii promoter	GO:0006366	368	0.166
organic hydroxy compound biosynthetic process	GO:1901617	21	0.165
synaptic vesicle localization	GO:0097479	53	0.165
meiotic nuclear division	GO:0007126	151	0.162
regulation of synaptic transmission	GO:0050804	69	0.162
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.162
cell recognition	GO:0008037	102	0.161
oocyte construction	GO:0007308	112	0.161
regulation of programmed cell death	GO:0043067	152	0.159
protein complex biogenesis	GO:0070271	201	0.158
localization of cell	GO:0051674	257	0.157
central nervous system development	GO:0007417	201	0.154
regulation of protein depolymerization	GO:1901879	27	0.152
morphogenesis of an epithelium	GO:0002009	276	0.151
multi organism reproductive behavior	GO:0044705	121	0.151
protein depolymerization	GO:0051261	31	0.150
apical junction assembly	GO:0043297	32	0.150
spermatid development	GO:0007286	98	0.149
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.149
secretion	GO:0046903	109	0.147
reproductive behavior	GO:0019098	122	0.146
positive regulation of cell proliferation	GO:0008284	47	0.146
morphogenesis of a branching epithelium	GO:0061138	45	0.146
death	GO:0016265	284	0.145
positive regulation of apoptotic process	GO:0043065	47	0.144
negative regulation of signal transduction	GO:0009968	206	0.143
organic substance catabolic process	GO:1901575	308	0.143
developmental maturation	GO:0021700	172	0.141
photoreceptor cell axon guidance	GO:0072499	23	0.139
alcohol metabolic process	GO:0006066	25	0.137
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.136
male gamete generation	GO:0048232	201	0.134
germarium derived egg chamber formation	GO:0007293	101	0.131
negative regulation of gene expression	GO:0010629	387	0.130
lipid metabolic process	GO:0006629	121	0.128
negative regulation of cell development	GO:0010721	62	0.128
establishment of spindle localization	GO:0051293	22	0.127
positive regulation of cell migration	GO:0030335	2	0.126
establishment or maintenance of apical basal cell polarity	GO:0035088	34	0.125
positive regulation of cell death	GO:0010942	69	0.125
negative regulation of protein complex disassembly	GO:0043242	23	0.124
regulation of dendrite development	GO:0050773	37	0.123
response to light stimulus	GO:0009416	124	0.123
positive regulation of growth	GO:0045927	75	0.122
regulation of neuron differentiation	GO:0045664	103	0.120
branching involved in open tracheal system development	GO:0060446	45	0.120
camera type eye development	GO:0043010	4	0.119
regulation of cell development	GO:0060284	215	0.119
head development	GO:0060322	135	0.118
synaptic vesicle exocytosis	GO:0016079	16	0.117
determination of adult lifespan	GO:0008340	137	0.117
positive regulation of cellular biosynthetic process	GO:0031328	316	0.117
negative regulation of response to stimulus	GO:0048585	258	0.116
organic hydroxy compound metabolic process	GO:1901615	83	0.115
tissue migration	GO:0090130	155	0.114
regulation of neurogenesis	GO:0050767	158	0.112
regulation of membrane potential	GO:0042391	35	0.111
regulation of protein metabolic process	GO:0051246	256	0.110
oocyte fate determination	GO:0030716	27	0.106
cell death	GO:0008219	279	0.106
compound eye development	GO:0048749	307	0.106
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.105
negative regulation of epithelial cell proliferation	GO:0050680	4	0.105
stem cell development	GO:0048864	79	0.100
protein catabolic process	GO:0030163	101	0.100
establishment of cell polarity	GO:0030010	40	0.099
positive regulation of secretion by cell	GO:1903532	20	0.099
striated muscle myosin thick filament assembly	GO:0071688	3	0.098
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.098
regulation of gene expression epigenetic	GO:0040029	128	0.098
response to organic substance	GO:0010033	284	0.095
compound eye morphogenesis	GO:0001745	249	0.093
purine containing compound catabolic process	GO:0072523	112	0.093
negative regulation of synapse assembly	GO:0051964	39	0.092
determination of dorsal ventral asymmetry	GO:0048262	3	0.091
glial cell differentiation	GO:0010001	35	0.090
regulation of endocytosis	GO:0030100	37	0.089
cortical cytoskeleton organization	GO:0030865	29	0.088
aging	GO:0007568	143	0.087
regulation of developmental growth	GO:0048638	174	0.087
regulation of cell morphogenesis	GO:0022604	163	0.086
ovarian follicle cell migration	GO:0007297	121	0.086
positive regulation of axonogenesis	GO:0050772	2	0.086
programmed cell death	GO:0012501	257	0.085
ensheathment of neurons	GO:0007272	10	0.085
neuronal stem cell division	GO:0036445	35	0.083
meiotic cell cycle	GO:0051321	171	0.083
developmental programmed cell death	GO:0010623	138	0.082
cellular nitrogen compound catabolic process	GO:0044270	165	0.082
neuronal action potential	GO:0019228	10	0.081
cellular component maintenance	GO:0043954	23	0.080
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.080
ventral cord development	GO:0007419	16	0.080
morphogenesis of a branching structure	GO:0001763	45	0.079
regulation of microtubule based process	GO:0032886	49	0.079
mating	GO:0007618	120	0.079
cellular protein localization	GO:0034613	160	0.078
oocyte differentiation	GO:0009994	145	0.077
axon ensheathment	GO:0008366	10	0.077
neuroblast proliferation	GO:0007405	74	0.076
response to oxygen containing compound	GO:1901700	200	0.076
cell proliferation	GO:0008283	299	0.075
regulation of hydrolase activity	GO:0051336	97	0.075
eye development	GO:0001654	323	0.074
endoderm formation	GO:0001706	3	0.073
positive regulation of phosphate metabolic process	GO:0045937	139	0.073
negative regulation of cell proliferation	GO:0008285	69	0.071
regulation of peptidase activity	GO:0052547	39	0.071
cytoplasm organization	GO:0007028	64	0.070
multi multicellular organism process	GO:0044706	123	0.070
sensory perception of smell	GO:0007608	80	0.070
germarium derived female germ line cyst formation	GO:0030727	42	0.068
determination of ventral identity	GO:0048264	1	0.068
regulation of transport	GO:0051049	181	0.068
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.068
transmission of nerve impulse	GO:0019226	12	0.066
response to oxidative stress	GO:0006979	86	0.066
epithelial tube morphogenesis	GO:0060562	88	0.065
regulation of secretion	GO:0051046	44	0.065
organic cyclic compound catabolic process	GO:1901361	168	0.065
macromolecule catabolic process	GO:0009057	161	0.065
regulation of multicellular organismal development	GO:2000026	414	0.065
protein modification process	GO:0036211	438	0.064
embryonic axis specification	GO:0000578	107	0.063
regulation of cellular localization	GO:0060341	136	0.063
negative regulation of microtubule polymerization or depolymerization	GO:0031111	21	0.063
gliogenesis	GO:0042063	80	0.063
protein transport	GO:0015031	155	0.062
compound eye photoreceptor development	GO:0042051	78	0.062
negative regulation of rna biosynthetic process	GO:1902679	240	0.061
positive regulation of rna biosynthetic process	GO:1902680	266	0.061
axon cargo transport	GO:0008088	29	0.061
camera type eye morphogenesis	GO:0048593	2	0.060
positive regulation of rna metabolic process	GO:0051254	271	0.060
germarium derived oocyte fate determination	GO:0007294	26	0.060
positive regulation of transcription dna templated	GO:0045893	266	0.059
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.059
nucleobase containing compound catabolic process	GO:0034655	165	0.059
regulation of secretion by cell	GO:1903530	39	0.058
open tracheal system development	GO:0007424	204	0.058
embryonic organ development	GO:0048568	50	0.058
positive regulation of axon extension	GO:0045773	2	0.057
regulation of neuron projection development	GO:0010975	69	0.057
detection of stimulus	GO:0051606	156	0.057
compound eye retinal cell programmed cell death	GO:0046667	23	0.057
oxidation reduction process	GO:0055114	123	0.057
actin polymerization or depolymerization	GO:0008154	31	0.056
negative regulation of nervous system development	GO:0051961	92	0.056
photoreceptor cell differentiation	GO:0046530	170	0.055
endodermal cell differentiation	GO:0035987	3	0.055
cellular response to chemical stimulus	GO:0070887	199	0.054
regulation of catalytic activity	GO:0050790	185	0.054
establishment of blood brain barrier	GO:0060856	16	0.053
microtubule polymerization or depolymerization	GO:0031109	39	0.053
positive regulation of cell communication	GO:0010647	250	0.053
nucleoside phosphate catabolic process	GO:1901292	110	0.052
negative regulation of cell differentiation	GO:0045596	143	0.052
single organism catabolic process	GO:0044712	228	0.052
negative regulation of cellular metabolic process	GO:0031324	382	0.050
eye photoreceptor cell development	GO:0042462	81	0.050
oviposition	GO:0018991	19	0.050
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.049
regulation of anatomical structure size	GO:0090066	163	0.049
associative learning	GO:0008306	65	0.049
multicellular organismal aging	GO:0010259	140	0.048
cell cell junction assembly	GO:0007043	38	0.048
epithelium migration	GO:0090132	148	0.048
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.047
positive regulation of multicellular organismal process	GO:0051240	143	0.047
spindle localization	GO:0051653	22	0.047
cell adhesion	GO:0007155	136	0.047
stem cell division	GO:0017145	69	0.047
single organismal cell cell adhesion	GO:0016337	45	0.047
adult locomotory behavior	GO:0008344	76	0.047
cardiovascular system development	GO:0072358	82	0.046
retina development in camera type eye	GO:0060041	4	0.046
response to starvation	GO:0042594	97	0.045
organic acid metabolic process	GO:0006082	103	0.045
negative regulation of cellular component organization	GO:0051129	108	0.044
signal release	GO:0023061	49	0.043
regulation of phosphate metabolic process	GO:0019220	210	0.043
intracellular transport	GO:0046907	228	0.043
nucleus localization	GO:0051647	34	0.043
single organism intracellular transport	GO:1902582	207	0.043
mapk cascade	GO:0000165	107	0.042
positive regulation of endocytosis	GO:0045807	22	0.042
exocytosis	GO:0006887	28	0.042
regulation of lipid metabolic process	GO:0019216	15	0.042
positive regulation of axon guidance	GO:1902669	1	0.042
digestive system development	GO:0055123	149	0.042
appendage morphogenesis	GO:0035107	397	0.042
purine containing compound metabolic process	GO:0072521	155	0.041
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.041
actin filament organization	GO:0007015	126	0.041
extracellular structure organization	GO:0043062	46	0.041
regulation of cell shape	GO:0008360	113	0.041
single organism biosynthetic process	GO:0044711	206	0.041
endomembrane system organization	GO:0010256	119	0.041
regulation of cell proliferation	GO:0042127	163	0.041
purine nucleotide metabolic process	GO:0006163	146	0.040
phagocytosis engulfment	GO:0006911	11	0.040
zonula adherens assembly	GO:0045186	6	0.040
establishment of ommatidial planar polarity	GO:0042067	49	0.040
regulation of actin cytoskeleton organization	GO:0032956	42	0.040
positive regulation of programmed cell death	GO:0043068	62	0.040
glycosyl compound metabolic process	GO:1901657	127	0.040
muscle structure development	GO:0061061	224	0.040
regulation of intracellular signal transduction	GO:1902531	236	0.039
nuclear division	GO:0000280	332	0.039
nucleotide metabolic process	GO:0009117	161	0.039
embryonic development via the syncytial blastoderm	GO:0001700	148	0.038
positive regulation of bmp signaling pathway	GO:0030513	5	0.038
pole plasm assembly	GO:0007315	61	0.038
epithelial cell migration	GO:0010631	148	0.037
cell junction assembly	GO:0034329	42	0.037
nucleoside metabolic process	GO:0009116	127	0.037
neuron projection extension	GO:1990138	32	0.037
protein polymerization	GO:0051258	42	0.037
positive regulation of response to stimulus	GO:0048584	323	0.037
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.037
synaptic vesicle priming	GO:0016082	1	0.036
negative regulation of cellular biosynthetic process	GO:0031327	277	0.036
negative regulation of developmental growth	GO:0048640	64	0.036
regulation of actin filament based process	GO:0032970	42	0.036
cellular response to organic substance	GO:0071310	132	0.036
organelle fission	GO:0048285	340	0.036
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.035
asymmetric protein localization	GO:0008105	33	0.035
gastrulation	GO:0007369	70	0.035
single organism membrane organization	GO:0044802	93	0.035
chromosome separation	GO:0051304	42	0.034
receptor mediated endocytosis	GO:0006898	21	0.034
regulation of nucleotide metabolic process	GO:0006140	62	0.034
vesicle organization	GO:0016050	44	0.034
circulatory system development	GO:0072359	82	0.033
feeding behavior	GO:0007631	50	0.033
glycosyl compound catabolic process	GO:1901658	112	0.033
positive regulation of feeding behavior	GO:2000253	8	0.033
ribonucleoside metabolic process	GO:0009119	127	0.033
regulation of purine nucleotide metabolic process	GO:1900542	62	0.032
purine ribonucleotide catabolic process	GO:0009154	109	0.032
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.032
secretion by cell	GO:0032940	101	0.031
purine ribonucleoside metabolic process	GO:0046128	127	0.031
chaeta development	GO:0022416	97	0.031
single organism cellular localization	GO:1902580	180	0.031
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.031
axis specification	GO:0009798	167	0.031
nucleotide catabolic process	GO:0009166	109	0.031
organophosphate metabolic process	GO:0019637	195	0.031
positive regulation of biosynthetic process	GO:0009891	316	0.031
developmental cell growth	GO:0048588	52	0.031
sensory perception of chemical stimulus	GO:0007606	116	0.031
molting cycle	GO:0042303	56	0.030
negative regulation of programmed cell death	GO:0043069	72	0.030
dorsal closure amnioserosa morphology change	GO:0046664	7	0.030
reproductive system development	GO:0061458	74	0.030
photoreceptor cell development	GO:0042461	96	0.030
motor neuron axon guidance	GO:0008045	58	0.030
biological adhesion	GO:0022610	138	0.029
heterocycle catabolic process	GO:0046700	166	0.029
regulation of cellular protein metabolic process	GO:0032268	243	0.029
decapentaplegic signaling pathway	GO:0008101	19	0.029
segmentation	GO:0035282	207	0.029
positive regulation of nervous system development	GO:0051962	69	0.028
cellular protein modification process	GO:0006464	438	0.028
response to endogenous stimulus	GO:0009719	119	0.028
purine ribonucleoside catabolic process	GO:0046130	112	0.028
necrotic cell death	GO:0070265	1	0.028
negative regulation of transcription dna templated	GO:0045892	237	0.028
regionalization	GO:0003002	416	0.028
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.028
ribonucleotide metabolic process	GO:0009259	145	0.028
negative regulation of apoptotic process	GO:0043066	63	0.028
head involution	GO:0008258	35	0.027
delamination	GO:0060232	8	0.027
cation transport	GO:0006812	110	0.027
aromatic compound catabolic process	GO:0019439	166	0.027
regulation of neurotransmitter secretion	GO:0046928	14	0.027
dendrite morphogenesis	GO:0048813	199	0.027
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.027
intracellular protein transport	GO:0006886	104	0.027
organophosphate catabolic process	GO:0046434	112	0.027
regulation of necrotic cell death	GO:0010939	1	0.027
chromosome segregation	GO:0007059	157	0.027
negative regulation of protein metabolic process	GO:0051248	85	0.026
regulation of pathway restricted smad protein phosphorylation	GO:0060393	1	0.026
positive regulation of phosphorus metabolic process	GO:0010562	139	0.026
positive regulation of protein metabolic process	GO:0051247	128	0.026
gtp catabolic process	GO:0006184	72	0.026
purine nucleoside metabolic process	GO:0042278	127	0.026
regulation of cell projection organization	GO:0031344	92	0.026
establishment of protein localization	GO:0045184	163	0.026
homeostatic process	GO:0042592	199	0.025
axon extension	GO:0048675	32	0.025
striated muscle cell differentiation	GO:0051146	90	0.025
neuron maturation	GO:0042551	31	0.025
anterior posterior axis specification embryo	GO:0008595	103	0.025
regulation of protein complex assembly	GO:0043254	42	0.025
ovarian follicle cell development	GO:0030707	248	0.025
ribonucleoside catabolic process	GO:0042454	112	0.024
non canonical wnt signaling pathway	GO:0035567	8	0.024
pole plasm protein localization	GO:0007318	10	0.024
regulation of system process	GO:0044057	36	0.024
neuroblast development	GO:0014019	13	0.024
synaptic vesicle fusion to presynaptic membrane	GO:0031629	7	0.024
blastoderm segmentation	GO:0007350	159	0.024
cellular hormone metabolic process	GO:0034754	23	0.024
oocyte axis specification	GO:0007309	108	0.024
establishment of mitotic spindle localization	GO:0040001	17	0.024
myofibril assembly	GO:0030239	36	0.023
small gtpase mediated signal transduction	GO:0007264	88	0.023
positive regulation of cellular component biogenesis	GO:0044089	80	0.023
embryonic pattern specification	GO:0009880	174	0.023
larval behavior	GO:0030537	42	0.023
regulation of proteolysis	GO:0030162	87	0.023
establishment of planar polarity	GO:0001736	87	0.023
guanosine containing compound metabolic process	GO:1901068	74	0.023
endodermal cell fate commitment	GO:0001711	3	0.023
asymmetric protein localization involved in cell fate determination	GO:0045167	9	0.023
positive regulation of cell motility	GO:2000147	3	0.023
positive regulation of signal transduction	GO:0009967	223	0.023
regulation of protein complex disassembly	GO:0043244	29	0.023
positive regulation of neuron differentiation	GO:0045666	26	0.023
positive regulation of catalytic activity	GO:0043085	118	0.023
negative regulation of mitotic cell cycle	GO:0045930	109	0.022
retina morphogenesis in camera type eye	GO:0060042	2	0.022
neural precursor cell proliferation	GO:0061351	75	0.022
regulation of apoptotic process	GO:0042981	130	0.022
spermatid differentiation	GO:0048515	114	0.022
purine ribonucleotide metabolic process	GO:0009150	145	0.022
heterotypic cell cell adhesion	GO:0034113	1	0.022
positive regulation of catabolic process	GO:0009896	105	0.022
membrane fusion	GO:0061025	42	0.022
cell division	GO:0051301	248	0.022
epithelial cell differentiation	GO:0030855	322	0.022
negative regulation of gene expression epigenetic	GO:0045814	77	0.022
reproductive structure development	GO:0048608	74	0.022
lipid storage	GO:0019915	38	0.022
positive regulation of cell projection organization	GO:0031346	29	0.022
organonitrogen compound biosynthetic process	GO:1901566	117	0.022
oxoacid metabolic process	GO:0043436	103	0.022
nucleoside triphosphate metabolic process	GO:0009141	120	0.021
organelle assembly	GO:0070925	198	0.021
imaginal disc growth	GO:0007446	37	0.021
regulation of tube size	GO:0035150	46	0.021
semaphorin plexin signaling pathway	GO:0071526	4	0.021
positive regulation of lipid biosynthetic process	GO:0046889	3	0.021
ribose phosphate metabolic process	GO:0019693	145	0.021
cellular component assembly involved in morphogenesis	GO:0010927	151	0.021
regulation of mitotic cell cycle	GO:0007346	190	0.021
purine nucleoside catabolic process	GO:0006152	112	0.021
positive regulation of cell development	GO:0010720	61	0.021
nitrogen compound transport	GO:0071705	85	0.021
single organism cell adhesion	GO:0098602	47	0.021
dorsal closure	GO:0007391	79	0.020
detection of abiotic stimulus	GO:0009582	66	0.020
dna metabolic process	GO:0006259	227	0.020
oocyte dorsal ventral axis specification	GO:0007310	34	0.020
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.020
sensory perception	GO:0007600	196	0.020
cellular homeostasis	GO:0019725	80	0.020
anatomical structure homeostasis	GO:0060249	97	0.019
stem cell maintenance	GO:0019827	67	0.019
cell junction organization	GO:0034330	57	0.019
regulation of actin polymerization or depolymerization	GO:0008064	27	0.019
septate junction assembly	GO:0019991	26	0.019
somatic stem cell division	GO:0048103	37	0.019
conditioned taste aversion	GO:0001661	3	0.019
chemical homeostasis	GO:0048878	92	0.019
protein localization to membrane	GO:0072657	19	0.019
tripartite regional subdivision	GO:0007351	103	0.019
adult behavior	GO:0030534	137	0.019
lamellipodium organization	GO:0097581	21	0.018
response to glucose	GO:0009749	2	0.018
positive regulation of gene expression	GO:0010628	290	0.018
cellular amine metabolic process	GO:0044106	12	0.018
striated muscle cell development	GO:0055002	50	0.018

beta-Spec disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.040
nervous system disease	DOID:863	0.040
disease of metabolism	DOID:0014667	0.029
disease of cellular proliferation	DOID:14566	0.026
cancer	DOID:162	0.021

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