IMP: Integrative Multi-species Prediction

Drosophila melanogaster

42 known processes

CG5871 (Dmel_CG5871)

CG5871 gene product from transcript CG5871-RA

(Aliases: Dmel\CG5871)

Entrez: 42518
FLYBASE: FBgn0038870
UniProtKB: Q9VDC9

Process Predictions
Disease Predictions

CG5871 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of gene expression	GO:0010629	387	0.242
gene silencing	GO:0016458	138	0.215
tube morphogenesis	GO:0035239	191	0.193
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.185
rna processing	GO:0006396	147	0.155
catabolic process	GO:0009056	409	0.144
dna conformation change	GO:0071103	105	0.143
transcription from rna polymerase ii promoter	GO:0006366	368	0.135
cellular protein modification process	GO:0006464	438	0.130
embryo development ending in birth or egg hatching	GO:0009792	152	0.125
cell proliferation	GO:0008283	299	0.122
locomotory behavior	GO:0007626	176	0.115
phosphorylation	GO:0016310	294	0.107
macromolecular complex assembly	GO:0065003	256	0.106
tube development	GO:0035295	244	0.106
positive regulation of transcription dna templated	GO:0045893	266	0.104
response to other organism	GO:0051707	293	0.103
tissue morphogenesis	GO:0048729	297	0.102
imaginal disc derived appendage development	GO:0048737	399	0.101
gene silencing by rna	GO:0031047	57	0.100
appendage morphogenesis	GO:0035107	397	0.097
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.096
regulation of protein metabolic process	GO:0051246	256	0.094
negative regulation of cellular biosynthetic process	GO:0031327	277	0.094
circadian rhythm	GO:0007623	105	0.092
positive regulation of biosynthetic process	GO:0009891	316	0.091
negative regulation of rna metabolic process	GO:0051253	251	0.089
defense response	GO:0006952	300	0.088
organic substance catabolic process	GO:1901575	308	0.086
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.086
regulation of cellular protein metabolic process	GO:0032268	243	0.082
regionalization	GO:0003002	416	0.082
macromolecule catabolic process	GO:0009057	161	0.081
protein localization	GO:0008104	284	0.081
defense response to other organism	GO:0098542	225	0.079
negative regulation of biosynthetic process	GO:0009890	277	0.076
single organism biosynthetic process	GO:0044711	206	0.072
oxoacid metabolic process	GO:0043436	103	0.070
organelle assembly	GO:0070925	198	0.069
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.066
endocytosis	GO:0006897	310	0.065
protein modification process	GO:0036211	438	0.061
mushroom body development	GO:0016319	70	0.058
response to organic substance	GO:0010033	284	0.058
response to biotic stimulus	GO:0009607	294	0.057
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.055
proteolysis	GO:0006508	192	0.055
response to external biotic stimulus	GO:0043207	293	0.055
cellular macromolecular complex assembly	GO:0034622	153	0.055
muscle structure development	GO:0061061	224	0.055
morphogenesis of an epithelium	GO:0002009	276	0.054
positive regulation of gene expression	GO:0010628	290	0.054
positive regulation of cellular biosynthetic process	GO:0031328	316	0.053
negative regulation of gene expression epigenetic	GO:0045814	77	0.051
chemotaxis	GO:0006935	249	0.051
developmental growth	GO:0048589	280	0.050
dna packaging	GO:0006323	91	0.050
cellular protein localization	GO:0034613	160	0.049
regulation of molecular function	GO:0065009	217	0.049
negative regulation of rna biosynthetic process	GO:1902679	240	0.049
eye development	GO:0001654	323	0.047
negative regulation of cellular metabolic process	GO:0031324	382	0.047
rhythmic process	GO:0048511	106	0.046
chromatin modification	GO:0016568	147	0.046
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.045
positive regulation of cellular protein metabolic process	GO:0032270	118	0.045
camera type eye morphogenesis	GO:0048593	2	0.043
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.042
response to bacterium	GO:0009617	198	0.042
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.042
protein transport	GO:0015031	155	0.041
multicellular organism growth	GO:0035264	46	0.038
organonitrogen compound metabolic process	GO:1901564	318	0.038
secretion by cell	GO:0032940	101	0.037
cellular macromolecule localization	GO:0070727	220	0.037
determination of adult lifespan	GO:0008340	137	0.036
eye morphogenesis	GO:0048592	260	0.036
chromatin organization	GO:0006325	207	0.036
head development	GO:0060322	135	0.036
aging	GO:0007568	143	0.036
regulation of protein modification process	GO:0031399	112	0.036
regulation of gene expression epigenetic	GO:0040029	128	0.035
cell motility	GO:0048870	251	0.034
negative regulation of transcription dna templated	GO:0045892	237	0.034
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.034
regulation of organelle organization	GO:0033043	196	0.032
neuron projection guidance	GO:0097485	241	0.032
posttranscriptional regulation of gene expression	GO:0010608	145	0.031
dna methylation or demethylation	GO:0044728	4	0.031
organic acid metabolic process	GO:0006082	103	0.031
regulation of multicellular organism growth	GO:0040014	40	0.030
multicellular organismal aging	GO:0010259	140	0.030
death	GO:0016265	284	0.030
positive regulation of macromolecule metabolic process	GO:0010604	405	0.030
cellular catabolic process	GO:0044248	372	0.030
mitotic cell cycle checkpoint	GO:0007093	88	0.029
mrna metabolic process	GO:0016071	124	0.029
intracellular protein transport	GO:0006886	104	0.029
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.029
taxis	GO:0042330	304	0.029
positive regulation of protein metabolic process	GO:0051247	128	0.028
response to oxygen containing compound	GO:1901700	200	0.028
peptidyl lysine modification	GO:0018205	57	0.028
digestive system development	GO:0055123	149	0.028
cellular response to dna damage stimulus	GO:0006974	223	0.028
mrna processing	GO:0006397	104	0.028
columnar cuboidal epithelial cell development	GO:0002066	249	0.028
axon development	GO:0061564	297	0.028
wing disc morphogenesis	GO:0007472	344	0.027
single organism intracellular transport	GO:1902582	207	0.027
immune system process	GO:0002376	347	0.027
small molecule metabolic process	GO:0044281	305	0.027
regulation of chromosome organization	GO:0033044	64	0.027
regulation of catabolic process	GO:0009894	170	0.027
regulation of cellular component biogenesis	GO:0044087	201	0.026
covalent chromatin modification	GO:0016569	106	0.026
cellular macromolecule catabolic process	GO:0044265	136	0.026
meiotic nuclear division	GO:0007126	151	0.026
positive regulation of rna biosynthetic process	GO:1902680	266	0.026
ncrna metabolic process	GO:0034660	43	0.026
positive regulation of developmental process	GO:0051094	143	0.025
appendage development	GO:0048736	401	0.025
dna metabolic process	GO:0006259	227	0.025
protein complex biogenesis	GO:0070271	201	0.025
protein complex assembly	GO:0006461	200	0.025
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.025
positive regulation of rna metabolic process	GO:0051254	271	0.025
response to nitrogen compound	GO:1901698	90	0.025
localization of cell	GO:0051674	257	0.024
protein catabolic process	GO:0030163	101	0.024
protein phosphorylation	GO:0006468	169	0.024
protein processing	GO:0016485	68	0.023
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.023
photoreceptor cell differentiation	GO:0046530	170	0.023
regulation of catalytic activity	GO:0050790	185	0.023
negative regulation of cell communication	GO:0010648	223	0.023
muscle organ development	GO:0007517	127	0.022
regulation of anatomical structure morphogenesis	GO:0022603	242	0.022
organelle fission	GO:0048285	340	0.022
protein maturation	GO:0051604	71	0.022
vesicle mediated transport	GO:0016192	381	0.022
ncrna processing	GO:0034470	30	0.022
camera type eye development	GO:0043010	4	0.022
positive regulation of cell communication	GO:0010647	250	0.022
axon guidance	GO:0007411	233	0.021
organic substance transport	GO:0071702	257	0.021
cellular amino acid metabolic process	GO:0006520	61	0.021
negative regulation of cellular protein metabolic process	GO:0032269	85	0.021
regulation of proteolysis	GO:0030162	87	0.021
body morphogenesis	GO:0010171	2	0.021
defense response to gram negative bacterium	GO:0050829	94	0.021
ribonucleoprotein complex assembly	GO:0022618	23	0.021
double strand break repair	GO:0006302	26	0.020
proteasomal protein catabolic process	GO:0010498	59	0.020
phagocytosis	GO:0006909	215	0.020
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.020
morphogenesis of a branching epithelium	GO:0061138	45	0.020
mitotic g2 m transition checkpoint	GO:0044818	70	0.019
regulation of protein catabolic process	GO:0042176	55	0.019
innate immune response	GO:0045087	144	0.019
regulation of cellular ketone metabolic process	GO:0010565	3	0.019
chromosome organization	GO:0051276	360	0.019
cellular response to nitrogen compound	GO:1901699	51	0.019
multi organism reproductive behavior	GO:0044705	121	0.019
immune response	GO:0006955	246	0.018
regulation of phosphate metabolic process	GO:0019220	210	0.018
g protein coupled receptor signaling pathway	GO:0007186	136	0.018
chromatin remodeling	GO:0006338	72	0.018
actin filament based process	GO:0030029	220	0.018
posttranscriptional gene silencing by rna	GO:0035194	45	0.018
negative regulation of protein metabolic process	GO:0051248	85	0.018
rna localization	GO:0006403	115	0.018
cell cycle checkpoint	GO:0000075	95	0.018
axonogenesis	GO:0007409	290	0.018
histone modification	GO:0016570	106	0.018
response to inorganic substance	GO:0010035	44	0.018
chemosensory behavior	GO:0007635	106	0.018
long term memory	GO:0007616	62	0.017
posttranscriptional gene silencing	GO:0016441	46	0.017
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.017
epithelial cell development	GO:0002064	274	0.017
positive regulation of response to stimulus	GO:0048584	323	0.017
cell death	GO:0008219	279	0.017
epithelial tube morphogenesis	GO:0060562	88	0.017
negative regulation of cell death	GO:0060548	81	0.016
brain development	GO:0007420	120	0.016
gland morphogenesis	GO:0022612	145	0.016
organic cyclic compound catabolic process	GO:1901361	168	0.016
chromatin assembly or disassembly	GO:0006333	52	0.016
exocrine system development	GO:0035272	162	0.016
gastrulation	GO:0007369	70	0.016
embryonic morphogenesis	GO:0048598	206	0.016
cell maturation	GO:0048469	144	0.016
negative regulation of mitotic cell cycle	GO:0045930	109	0.015
central nervous system development	GO:0007417	201	0.015
rna splicing via transesterification reactions	GO:0000375	73	0.015
phosphatidylinositol 3 kinase signaling	GO:0014065	4	0.015
establishment of protein localization	GO:0045184	163	0.015
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.015
protein localization to organelle	GO:0033365	82	0.015
response to lipopolysaccharide	GO:0032496	4	0.015
positive regulation of organelle organization	GO:0010638	65	0.015
organophosphate metabolic process	GO:0019637	195	0.015
regulation of cellular localization	GO:0060341	136	0.015
growth	GO:0040007	359	0.015
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.015
secretion	GO:0046903	109	0.015
heterochromatin organization	GO:0070828	25	0.015
mitotic cell cycle phase transition	GO:0044772	138	0.015
positive regulation of molecular function	GO:0044093	136	0.015
digestive tract morphogenesis	GO:0048546	127	0.015
dorsal ventral pattern formation	GO:0009953	133	0.014
single organism behavior	GO:0044708	391	0.014
intracellular signal transduction	GO:0035556	300	0.014
epithelial cell differentiation	GO:0030855	322	0.014
cellular response to oxygen containing compound	GO:1901701	79	0.014
positive regulation of protein modification process	GO:0031401	58	0.014
apoptotic process	GO:0006915	159	0.014
cellular amine metabolic process	GO:0044106	12	0.014
homeostatic process	GO:0042592	199	0.014
programmed cell death	GO:0012501	257	0.014
compound eye morphogenesis	GO:0001745	249	0.014
salivary gland development	GO:0007431	162	0.014
response to abiotic stimulus	GO:0009628	341	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
establishment of protein localization to organelle	GO:0072594	62	0.014
nucleobase containing compound catabolic process	GO:0034655	165	0.014
regulation of localization	GO:0032879	275	0.014
modification dependent protein catabolic process	GO:0019941	78	0.014
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.013
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.013
intracellular transport	GO:0046907	228	0.013
protein import	GO:0017038	55	0.013
modification dependent macromolecule catabolic process	GO:0043632	79	0.013
dendrite development	GO:0016358	204	0.013
regulation of cell death	GO:0010941	173	0.013
cell migration	GO:0016477	238	0.013
production of small rna involved in gene silencing by rna	GO:0070918	15	0.013
oocyte construction	GO:0007308	112	0.013
cellular protein complex assembly	GO:0043623	71	0.013
regulation of anatomical structure size	GO:0090066	163	0.013
embryonic pattern specification	GO:0009880	174	0.013
compound eye photoreceptor cell differentiation	GO:0001751	140	0.013
signal transduction by phosphorylation	GO:0023014	107	0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.012
response to oxidative stress	GO:0006979	86	0.012
cellular response to organic substance	GO:0071310	132	0.012
organonitrogen compound catabolic process	GO:1901565	128	0.012
imaginal disc derived wing morphogenesis	GO:0007476	337	0.012
locomotor rhythm	GO:0045475	56	0.012
multi organism behavior	GO:0051705	175	0.012
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.012
ubiquitin dependent protein catabolic process	GO:0006511	78	0.012
rna 3 end processing	GO:0031123	45	0.012
regulation of defense response	GO:0031347	102	0.012
cardiovascular system development	GO:0072358	82	0.012
positive regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032436	19	0.012
peptidyl amino acid modification	GO:0018193	105	0.012
methylation	GO:0032259	47	0.012
regulation of proteasomal protein catabolic process	GO:0061136	39	0.012
protein targeting	GO:0006605	64	0.012
response to organonitrogen compound	GO:0010243	75	0.011
oocyte axis specification	GO:0007309	108	0.011
regulation of programmed cell death	GO:0043067	152	0.011
glycerophospholipid metabolic process	GO:0006650	23	0.011
digestive tract development	GO:0048565	149	0.011
regulation of cellular amine metabolic process	GO:0033238	3	0.011
protein targeting to nucleus	GO:0044744	51	0.011
axis specification	GO:0009798	167	0.011
organophosphate biosynthetic process	GO:0090407	46	0.011
pigment cell differentiation	GO:0050931	3	0.011
response to organic cyclic compound	GO:0014070	89	0.011
sensory organ morphogenesis	GO:0090596	260	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
nuclear division	GO:0000280	332	0.011
salivary gland morphogenesis	GO:0007435	145	0.011
positive regulation of growth	GO:0045927	75	0.011
reproductive behavior	GO:0019098	122	0.011
histone h2a acetylation	GO:0043968	1	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.010
regulation of transport	GO:0051049	181	0.010
gene silencing by mirna	GO:0035195	22	0.010
cellular component assembly involved in morphogenesis	GO:0010927	151	0.010
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.010
embryonic development via the syncytial blastoderm	GO:0001700	148	0.010
regulation of chromatin modification	GO:1903308	28	0.010
rna splicing	GO:0008380	83	0.010

CG5871 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
eye and adnexa disease	DOID:1492	0.037
nervous system disease	DOID:863	0.037
disease of anatomical entity	DOID:7	0.037
sensory system disease	DOID:0050155	0.037
eye disease	DOID:5614	0.019

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