Drosophila melanogaster

81 known processes

bru (Dmel_CG2478)

brunelleschi

(Aliases: CG2478,Dmel\CG2478,38D.28)

bru biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiotic cytokinesisGO:0033206330.999
meiosis iiGO:0007135230.999
cytokinetic processGO:0032506270.997
meiotic nuclear divisionGO:00071261510.997
meiotic cell cycleGO:00513211710.997
meiotic cell cycle processGO:19030461320.995
meiosis iGO:0007127590.986
cytoskeleton dependent cytokinesisGO:0061640810.983
meiotic spindle organizationGO:0000212360.981
nuclear divisionGO:00002803320.980
organelle fissionGO:00482853400.978
meiosis ii cytokinesisGO:0007111110.975
meiosis i cytokinesisGO:0007110120.963
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.944
regulation of protein complex disassemblyGO:0043244290.943
actomyosin contractile ring contractionGO:0000916120.939
meiotic spindle stabilizationGO:004314780.932
contractile ring contractionGO:0036213120.922
regulation of spindle organizationGO:0090224170.881
spindle organizationGO:00070512530.866
cytokinesisGO:0000910900.854
male meiosisGO:0007140520.844
spindle stabilizationGO:0043146140.798
regulation of protein depolymerizationGO:1901879270.787
negative regulation of microtubule depolymerizationGO:0007026210.766
regulation of microtubule depolymerizationGO:0031114240.761
actomyosin contractile ring assemblyGO:0000915100.754
negative regulation of protein complex disassemblyGO:0043242230.754
negative regulation of protein depolymerizationGO:1901880230.752
microtubule depolymerizationGO:0007019250.718
male meiosis cytokinesisGO:0007112260.707
cell divisionGO:00513012480.703
regulation of microtubule cytoskeleton organizationGO:0070507410.702
actomyosin contractile ring organizationGO:0044837100.636
protein complex disassemblyGO:0043241360.617
protein depolymerizationGO:0051261310.560
assembly of actomyosin apparatus involved in cytokinesisGO:0000912110.529
negative regulation of cytoskeleton organizationGO:0051494300.502
regulation of cell cycle processGO:00105641810.485
regulation of microtubule based processGO:0032886490.480
microtubule polymerization or depolymerizationGO:0031109390.478
actomyosin structure organizationGO:0031032560.437
regulation of cytoskeleton organizationGO:0051493890.432
regulation of microtubule polymerization or depolymerizationGO:0031110270.398
negative regulation of cellular component organizationGO:00511291080.356
spermatocyte divisionGO:0048137130.281
regulation of cell cycleGO:00517262910.266
cellular protein complex disassemblyGO:0043624350.261
cellular component disassemblyGO:0022411460.231
male meiosis chromosome segregationGO:0007060100.205
spindle assemblyGO:0051225800.193
macromolecular complex assemblyGO:00650032560.188
regulation of organelle organizationGO:00330431960.182
meiotic chromosome segregationGO:0045132590.152
organelle assemblyGO:00709251980.117
macromolecular complex disassemblyGO:0032984370.113
chromosome segregationGO:00070591570.101
protein complex assemblyGO:00064612000.083
protein complex biogenesisGO:00702712010.078
spermatogenesisGO:00072832000.075
actin cytoskeleton organizationGO:00300362060.062
actin filament based processGO:00300292200.059
imaginal disc derived appendage developmentGO:00487373990.057
appendage morphogenesisGO:00351073970.055
endomembrane system organizationGO:00102561190.051
gland morphogenesisGO:00226121450.050
sphingolipid metabolic processGO:0006665190.047
positive regulation of macromolecule metabolic processGO:00106044050.046
organonitrogen compound metabolic processGO:19015643180.043
negative regulation of organelle organizationGO:0010639560.042
imaginal disc derived appendage morphogenesisGO:00351143950.041
vesicle mediated transportGO:00161923810.040
response to abiotic stimulusGO:00096283410.039
positive regulation of rna metabolic processGO:00512542710.039
wing disc morphogenesisGO:00074723440.038
membrane organizationGO:00610241120.037
regionalizationGO:00030024160.036
synaptic transmissionGO:00072682880.036
small molecule metabolic processGO:00442813050.035
male gamete generationGO:00482322010.035
catabolic processGO:00090564090.035
phagocytosisGO:00069092150.034
cell motilityGO:00488702510.033
embryonic axis specificationGO:00005781070.033
establishment of localization in cellGO:00516494020.033
nucleus organizationGO:0006997450.032
organic substance catabolic processGO:19015753080.032
aromatic compound catabolic processGO:00194391660.031
programmed cell deathGO:00125012570.031
positive regulation of nucleobase containing compound metabolic processGO:00459353320.029
positive regulation of nitrogen compound metabolic processGO:00511733540.029
positive regulation of cellular biosynthetic processGO:00313283160.029
positive regulation of biosynthetic processGO:00098913160.028
regulation of cell cycle phase transitionGO:19019871300.027
rac protein signal transductionGO:001660130.027
cell cell signaling involved in cell fate commitmentGO:00451682100.025
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.025
membrane lipid metabolic processGO:0006643220.025
chromosome organizationGO:00512763600.025
organonitrogen compound biosynthetic processGO:19015661170.025
segmentationGO:00352822070.025
blastoderm segmentationGO:00073501590.025
regulation of cellular component biogenesisGO:00440872010.024
endocytosisGO:00068973100.024
carbohydrate derivative metabolic processGO:19011352170.024
mitotic spindle organizationGO:00070522200.024
mitotic cell cycle phase transitionGO:00447721380.024
histolysisGO:00075591020.024
macromolecule catabolic processGO:00090571610.024
establishment or maintenance of bipolar cell polarityGO:0061245340.024
male meiosis iGO:000714190.023
maintenance of protein locationGO:0045185280.023
body morphogenesisGO:001017120.022
regulation of cellular amine metabolic processGO:003323830.022
mesodermal cell migrationGO:000807870.022
regulation of synapse structure and activityGO:00508031280.022
salivary gland developmentGO:00074311620.022
nucleobase containing small molecule metabolic processGO:00550861740.022
regulation of developmental growthGO:00486381740.022
eye morphogenesisGO:00485922600.021
lateral inhibitionGO:00463312060.021
protein modification processGO:00362114380.021
microtubule cytoskeleton organization involved in mitosisGO:1902850520.021
regulation of intracellular signal transductionGO:19025312360.021
regulation of nervous system developmentGO:00519602480.020
compound eye photoreceptor cell differentiationGO:00017511400.020
photoreceptor cell differentiationGO:00465301700.020
cell deathGO:00082192790.019
anterior posterior pattern specificationGO:00099521360.019
localization of cellGO:00516742570.019
stem cell divisionGO:0017145690.019
carboxylic acid metabolic processGO:0019752920.019
rho protein signal transductionGO:0007266140.019
photoreceptor cell developmentGO:0042461960.019
regulation of synapse organizationGO:00508071100.018
cellular amine metabolic processGO:0044106120.018
purine containing compound metabolic processGO:00725211550.018
mrna processingGO:00063971040.018
purine ribonucleotide catabolic processGO:00091541090.018
salivary gland morphogenesisGO:00074351450.018
imaginal disc derived wing morphogenesisGO:00074763370.018
positive regulation of transcription dna templatedGO:00458932660.018
positive regulation of macromolecule biosynthetic processGO:00105572830.018
heterocycle catabolic processGO:00467001660.018
regulation of mitotic cell cycle phase transitionGO:19019901300.018
cellular catabolic processGO:00442483720.017
nucleobase containing compound catabolic processGO:00346551650.017
oxoacid metabolic processGO:00434361030.017
developmental growthGO:00485892800.017
positive regulation of gene expressionGO:00106282900.017
eye photoreceptor cell developmentGO:0042462810.017
ribonucleoside catabolic processGO:00424541120.017
single organism biosynthetic processGO:00447112060.017
embryonic pattern specificationGO:00098801740.017
compound eye photoreceptor developmentGO:0042051780.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.016
modification dependent macromolecule catabolic processGO:0043632790.016
cellular macromolecule localizationGO:00707272200.016
compound eye developmentGO:00487493070.016
regulation of cellular ketone metabolic processGO:001056530.016
cellular macromolecule catabolic processGO:00442651360.016
golgi organizationGO:0007030660.016
epithelial cell differentiationGO:00308553220.016
positive regulation of rna biosynthetic processGO:19026802660.016
regulation of programmed cell deathGO:00430671520.016
regulation of cellular amino acid metabolic processGO:000652100.016
gland developmentGO:00487321910.015
regulation of cell projection organizationGO:0031344920.015
tripartite regional subdivisionGO:00073511030.015
negative regulation of gene expressionGO:00106293870.015
regulation of cellular component sizeGO:0032535980.015
very long chain fatty acid metabolic processGO:000003840.015
mitotic nuclear divisionGO:00070672130.015
spindle assembly involved in mitosisGO:0090307500.015
forebrain developmentGO:003090020.015
apoptotic processGO:00069151590.015
maintenance of protein location in cellGO:0032507260.015
synapse assemblyGO:00074161430.015
protein localizationGO:00081042840.014
amine metabolic processGO:0009308120.014
cell cycle phase transitionGO:00447701400.014
maintenance of location in cellGO:0051651280.014
multicellular organismal agingGO:00102591400.014
establishment or maintenance of apical basal cell polarityGO:0035088340.014
tissue deathGO:00162711020.014
compound eye morphogenesisGO:00017452490.014
exocrine system developmentGO:00352721620.014
metal ion homeostasisGO:0055065440.014
purine containing compound catabolic processGO:00725231120.014
organophosphate metabolic processGO:00196371950.014
pronuclear migrationGO:003504640.014
cell migrationGO:00164772380.014
nuclear envelope organizationGO:000699870.014
appendage developmentGO:00487364010.013
columnar cuboidal epithelial cell differentiationGO:00020652560.013
anterior posterior axis specification embryoGO:00085951030.013
positive regulation of multicellular organismal processGO:00512401430.013
mitotic cytokinesisGO:0000281500.013
sister chromatid segregationGO:0000819920.013
cilium organizationGO:0044782410.013
adult behaviorGO:00305341370.013
regulation of multicellular organismal developmentGO:20000264140.013
regulation of compound eye cone cell fate specificationGO:004268240.013
negative regulation of mitotic cell cycleGO:00459301090.013
nucleotide metabolic processGO:00091171610.013
spermatid developmentGO:0007286980.013
cellular ketone metabolic processGO:0042180240.013
regulation of neuron projection developmentGO:0010975690.013
cytoplasmic transport nurse cell to oocyteGO:0007303120.012
telencephalon developmentGO:002153720.012
maintenance of locationGO:0051235730.012
plasma membrane organizationGO:0007009260.012
protein catabolic processGO:00301631010.012
regulation of mitotic cell cycleGO:00073461900.012
positive regulation of protein localization to plasma membraneGO:190307830.012
lipid metabolic processGO:00066291210.012
neuroblast proliferationGO:0007405740.012
intracellular signal transductionGO:00355563000.012
pseudocleavage involved in syncytial blastoderm formationGO:003058990.012
cation homeostasisGO:0055080510.012
cellular response to dna damage stimulusGO:00069742230.012
regulation of phosphorus metabolic processGO:00511742100.012
regulation of mrna processingGO:0050684710.012
purine nucleotide metabolic processGO:00061631460.012
spindle elongationGO:0051231830.012
protein phosphorylationGO:00064681690.012
regulation of organ morphogenesisGO:2000027780.012
cell projection assemblyGO:0030031940.012
ras protein signal transductionGO:0007265880.012
regulation of neuron differentiationGO:00456641030.012
ribose phosphate metabolic processGO:00196931450.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of catabolic processGO:00098941700.011
germline ring canal formationGO:0030725130.011
fatty acid elongationGO:003049730.011
germ line stem cell divisionGO:0042078250.011
spindle assembly involved in male meiosisGO:000705350.011
alternative mrna splicing via spliceosomeGO:0000380600.011
regulation of anatomical structure sizeGO:00900661630.011
snrna processingGO:0016180140.011
transcription from rna polymerase ii promoterGO:00063663680.011
connective tissue developmentGO:006144830.011
establishment of mitotic spindle orientationGO:0000132130.011
carbohydrate metabolic processGO:0005975820.011
cellular response to radiationGO:0071478520.011
nucleoside catabolic processGO:00091641120.011
single organism behaviorGO:00447083910.011
phosphorylationGO:00163102940.010
single organism membrane organizationGO:0044802930.010
cellular protein modification processGO:00064644380.010
purine ribonucleoside metabolic processGO:00461281270.010
salivary gland histolysisGO:0035070880.010
establishment of planar polarityGO:0001736870.010
cytoplasmic transportGO:00164821300.010
cellular macromolecular complex assemblyGO:00346221530.010
establishment or maintenance of cell polarityGO:00071631670.010
chemotaxisGO:00069352490.010
regulation of cell developmentGO:00602842150.010
synaptic growth at neuromuscular junctionGO:00511241190.010
cellular amino acid metabolic processGO:0006520610.010

bru disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.026
disease of anatomical entityDOID:700.026
autosomal dominant nonsyndromic deafnessDOID:005056400.026
nonsyndromic deafnessDOID:005056300.026
nervous system diseaseDOID:86300.026
auditory system diseaseDOID:274200.026