IMP: Integrative Multi-species Prediction

Drosophila melanogaster

64 known processes

Mgat1 (Dmel_CG13431)

UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I

(Aliases: CG13431,MGAT1,Dmel\CG13431,dMGAT1,GlcNAc-TI)

Entrez: 37323
FLYBASE: FBgn0034521
UniProtKB: Q60GL7

Process Predictions
Disease Predictions

Mgat1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
melanotic encapsulation of foreign target	GO:0035011	30	0.691
protein modification process	GO:0036211	438	0.588
immune effector process	GO:0002252	98	0.524
detection of stimulus	GO:0051606	156	0.480
single organism behavior	GO:0044708	391	0.430
encapsulation of foreign target	GO:0035010	38	0.429
phenol containing compound metabolic process	GO:0018958	57	0.360
modification dependent macromolecule catabolic process	GO:0043632	79	0.318
organic hydroxy compound metabolic process	GO:1901615	83	0.283
single organism carbohydrate metabolic process	GO:0044723	72	0.278
protein n linked glycosylation	GO:0006487	9	0.262
n glycan processing	GO:0006491	3	0.234
vesicle mediated transport	GO:0016192	381	0.192
growth	GO:0040007	359	0.186
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.170
immune system process	GO:0002376	347	0.163
regulation of localization	GO:0032879	275	0.162
regulation of transport	GO:0051049	181	0.148
macromolecule catabolic process	GO:0009057	161	0.143
intracellular signal transduction	GO:0035556	300	0.143
protein catabolic process	GO:0030163	101	0.138
dendrite development	GO:0016358	204	0.136
dendrite morphogenesis	GO:0048813	199	0.131
carbohydrate derivative biosynthetic process	GO:1901137	85	0.131
regulation of cell proliferation	GO:0042127	163	0.128
regulation of multi organism process	GO:0043900	131	0.126
glycoprotein metabolic process	GO:0009100	41	0.122
ubiquitin dependent protein catabolic process	GO:0006511	78	0.109
cellular macromolecule catabolic process	GO:0044265	136	0.104
cellular response to organic substance	GO:0071310	132	0.099
regulation of nervous system development	GO:0051960	248	0.095
regulation of phosphorus metabolic process	GO:0051174	210	0.093
death	GO:0016265	284	0.092
modification dependent protein catabolic process	GO:0019941	78	0.090
neuron projection guidance	GO:0097485	241	0.088
gland development	GO:0048732	191	0.083
cell death	GO:0008219	279	0.082
cellular protein modification process	GO:0006464	438	0.081
carbohydrate metabolic process	GO:0005975	82	0.077
organelle fission	GO:0048285	340	0.077
secondary metabolic process	GO:0019748	75	0.074
regulation of cell development	GO:0060284	215	0.072
regulation of cell cycle	GO:0051726	291	0.071
chromosome organization	GO:0051276	360	0.070
regulation of cell differentiation	GO:0045595	302	0.070
positive regulation of nervous system development	GO:0051962	69	0.070
glycoprotein biosynthetic process	GO:0009101	41	0.065
phosphorylation	GO:0016310	294	0.065
positive regulation of cell differentiation	GO:0045597	64	0.064
negative regulation of growth	GO:0045926	84	0.062
programmed cell death	GO:0012501	257	0.061
chromatin organization	GO:0006325	207	0.059
positive regulation of cellular component organization	GO:0051130	156	0.058
ras protein signal transduction	GO:0007265	88	0.058
negative regulation of programmed cell death	GO:0043069	72	0.056
regulation of cellular localization	GO:0060341	136	0.055
pigment metabolic process	GO:0042440	84	0.055
homeostatic process	GO:0042592	199	0.053
negative regulation of cell communication	GO:0010648	223	0.052
organic substance catabolic process	GO:1901575	308	0.049
regulation of programmed cell death	GO:0043067	152	0.049
synaptic transmission	GO:0007268	288	0.049
endocytosis	GO:0006897	310	0.048
negative regulation of growth of symbiont involved in interaction with host	GO:0044146	9	0.048
protein localization	GO:0008104	284	0.048
protein deglycosylation	GO:0006517	1	0.048
regulation of organelle organization	GO:0033043	196	0.047
cell proliferation	GO:0008283	299	0.046
protein transport	GO:0015031	155	0.043
cell division	GO:0051301	248	0.041
regulation of cell death	GO:0010941	173	0.041
cellular macromolecule localization	GO:0070727	220	0.041
mushroom body development	GO:0016319	70	0.039
cellular response to ketone	GO:1901655	17	0.039
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.039
regulation of protein localization	GO:0032880	76	0.038
proteolysis	GO:0006508	192	0.037
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.037
response to ketone	GO:1901654	34	0.037
regulation of multicellular organismal development	GO:2000026	414	0.036
regulation of neurogenesis	GO:0050767	158	0.035
cell motility	GO:0048870	251	0.034
brain development	GO:0007420	120	0.034
open tracheal system development	GO:0007424	204	0.034
positive regulation of signaling	GO:0023056	243	0.033
positive regulation of cellular biosynthetic process	GO:0031328	316	0.033
regulation of protein transport	GO:0051223	57	0.033
oocyte axis specification	GO:0007309	108	0.033
cellular protein catabolic process	GO:0044257	83	0.032
regulation of vesicle mediated transport	GO:0060627	59	0.032
protein complex biogenesis	GO:0070271	201	0.031
positive regulation of phosphate metabolic process	GO:0045937	139	0.031
single organism biosynthetic process	GO:0044711	206	0.031
catabolic process	GO:0009056	409	0.030
response to biotic stimulus	GO:0009607	294	0.030
macromolecular complex assembly	GO:0065003	256	0.030
response to abiotic stimulus	GO:0009628	341	0.029
secretion by cell	GO:0032940	101	0.029
organophosphate biosynthetic process	GO:0090407	46	0.029
immune response	GO:0006955	246	0.029
regulation of intracellular transport	GO:0032386	64	0.028
sleep	GO:0030431	49	0.028
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.028
carbohydrate derivative metabolic process	GO:1901135	217	0.028
negative regulation of signal transduction	GO:0009968	206	0.028
positive regulation of gene expression	GO:0010628	290	0.027
heterocycle catabolic process	GO:0046700	166	0.027
regulation of growth	GO:0040008	233	0.027
positive regulation of neurogenesis	GO:0050769	41	0.027
intracellular transport	GO:0046907	228	0.027
positive regulation of developmental process	GO:0051094	143	0.027
cellular response to endogenous stimulus	GO:0071495	80	0.026
positive regulation of cell development	GO:0010720	61	0.026
establishment of localization in cell	GO:0051649	402	0.026
macromolecule glycosylation	GO:0043413	32	0.026
negative regulation of response to stimulus	GO:0048585	258	0.026
regulation of phosphate metabolic process	GO:0019220	210	0.025
response to organic cyclic compound	GO:0014070	89	0.025
cellular response to chemical stimulus	GO:0070887	199	0.025
apoptotic process	GO:0006915	159	0.025
organic substance transport	GO:0071702	257	0.024
cellular catabolic process	GO:0044248	372	0.024
response to other organism	GO:0051707	293	0.024
positive regulation of response to stimulus	GO:0048584	323	0.024
vesicle localization	GO:0051648	55	0.024
anatomical structure homeostasis	GO:0060249	97	0.023
proteasomal protein catabolic process	GO:0010498	59	0.023
developmental growth	GO:0048589	280	0.023
cellular response to lipid	GO:0071396	20	0.022
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.021
regulation of molecular function	GO:0065009	217	0.021
signal transduction by phosphorylation	GO:0023014	107	0.021
organ growth	GO:0035265	56	0.021
protein import into nucleus	GO:0006606	51	0.021
oligosaccharide metabolic process	GO:0009311	18	0.020
establishment of mitochondrion localization microtubule mediated	GO:0034643	6	0.020
regulation of ras protein signal transduction	GO:0046578	93	0.020
positive regulation of signal transduction	GO:0009967	223	0.020
positive regulation of phosphorus metabolic process	GO:0010562	139	0.020
nucleus organization	GO:0006997	45	0.020
positive regulation of catalytic activity	GO:0043085	118	0.019
intracellular mrna localization	GO:0008298	66	0.019
multi organism behavior	GO:0051705	175	0.019
cellularization	GO:0007349	90	0.019
inositol lipid mediated signaling	GO:0048017	4	0.019
establishment of organelle localization	GO:0051656	122	0.019
interspecies interaction between organisms	GO:0044419	16	0.019
regulation of secretion	GO:0051046	44	0.019
neurological system process	GO:0050877	358	0.018
regulation of transferase activity	GO:0051338	58	0.018
aromatic compound catabolic process	GO:0019439	166	0.018
regulation of synaptic transmission	GO:0050804	69	0.018
axonogenesis	GO:0007409	290	0.018
cellular response to organic cyclic compound	GO:0071407	32	0.018
mapk cascade	GO:0000165	107	0.018
negative regulation of gene expression	GO:0010629	387	0.017
positive regulation of multicellular organismal process	GO:0051240	143	0.017
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.017
establishment of protein localization	GO:0045184	163	0.017
embryonic pattern specification	GO:0009880	174	0.017
single organism intracellular transport	GO:1902582	207	0.017
cell aging	GO:0007569	2	0.017
regulation of establishment of protein localization	GO:0070201	61	0.017
transcription from rna polymerase ii promoter	GO:0006366	368	0.017
regulation of immune system process	GO:0002682	176	0.017
central nervous system development	GO:0007417	201	0.016
negative regulation of developmental process	GO:0051093	201	0.016
phagocytosis	GO:0006909	215	0.016
response to oxygen containing compound	GO:1901700	200	0.016
negative regulation of apoptotic process	GO:0043066	63	0.015
nitrogen compound transport	GO:0071705	85	0.015
eye development	GO:0001654	323	0.015
regulation of apoptotic process	GO:0042981	130	0.015
positive regulation of immune system process	GO:0002684	68	0.015
chemical homeostasis	GO:0048878	92	0.015
response to nitrogen compound	GO:1901698	90	0.015
protein complex assembly	GO:0006461	200	0.014
positive regulation of transport	GO:0051050	92	0.014
negative regulation of immune system process	GO:0002683	50	0.014
regulation of mitotic cell cycle	GO:0007346	190	0.014
regulation of cell morphogenesis	GO:0022604	163	0.014
innate immune response	GO:0045087	144	0.014
axon development	GO:0061564	297	0.014
regulation of protein catabolic process	GO:0042176	55	0.014
blastoderm segmentation	GO:0007350	159	0.014
erk1 and erk2 cascade	GO:0070371	39	0.013
positive regulation of rna metabolic process	GO:0051254	271	0.013
carbohydrate derivative catabolic process	GO:1901136	118	0.013
organophosphate metabolic process	GO:0019637	195	0.013
microtubule organizing center organization	GO:0031023	168	0.013
organonitrogen compound metabolic process	GO:1901564	318	0.013
positive regulation of intracellular signal transduction	GO:1902533	116	0.013
negative regulation of multi organism process	GO:0043901	29	0.013
regulation of intracellular protein transport	GO:0033157	46	0.013
regulation of cellular protein metabolic process	GO:0032268	243	0.013
negative regulation of cell differentiation	GO:0045596	143	0.013
regulation of neuron projection development	GO:0010975	69	0.013
regulation of phosphorylation	GO:0042325	147	0.013
regulation of catabolic process	GO:0009894	170	0.013
negative regulation of erk1 and erk2 cascade	GO:0070373	3	0.012
mitotic cell cycle checkpoint	GO:0007093	88	0.012
negative regulation of mitotic cell cycle	GO:0045930	109	0.012
protein phosphorylation	GO:0006468	169	0.012
establishment of mitochondrion localization	GO:0051654	7	0.012
embryonic morphogenesis	GO:0048598	206	0.012
mrna processing	GO:0006397	104	0.012
developmental maturation	GO:0021700	172	0.012
negative regulation of multicellular organismal process	GO:0051241	142	0.012
positive regulation of protein phosphorylation	GO:0001934	34	0.012
regulation of cell cycle process	GO:0010564	181	0.012
cellular response to oxygen containing compound	GO:1901701	79	0.012
response to oxidative stress	GO:0006979	86	0.012
regulation of cell division	GO:0051302	72	0.012
positive regulation of cell proliferation	GO:0008284	47	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
single organism membrane organization	GO:0044802	93	0.012
developmental programmed cell death	GO:0010623	138	0.011
detection of external stimulus	GO:0009581	66	0.011
rna localization	GO:0006403	115	0.011
positive regulation of cell communication	GO:0010647	250	0.011
cell maturation	GO:0048469	144	0.011
cytoskeleton dependent cytokinesis	GO:0061640	81	0.011
locomotory behavior	GO:0007626	176	0.011
cilium assembly	GO:0042384	38	0.011
negative regulation of intracellular signal transduction	GO:1902532	57	0.011
morphogenesis of embryonic epithelium	GO:0016331	94	0.011
response to alcohol	GO:0097305	95	0.010
symbiosis encompassing mutualism through parasitism	GO:0044403	16	0.010
mitotic nuclear division	GO:0007067	213	0.010
glycosylation	GO:0070085	36	0.010
secretion	GO:0046903	109	0.010
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.010
regulation of protein complex assembly	GO:0043254	42	0.010

Mgat1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.059
musculoskeletal system disease	DOID:17	0.016
connective tissue disease	DOID:65	0.016
bone disease	DOID:0080001	0.016
nervous system disease	DOID:863	0.011

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network