Drosophila melanogaster

27 known processes

Wwox (Dmel_CG7221)

CG7221 gene product from transcript CG7221-RA

(Aliases: CG7221,Dmel\CG7221,DmWWOX,anon-EST:Posey177)

Wwox biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular protein modification processGO:00064644380.198
protein modification processGO:00362114380.166
small molecule metabolic processGO:00442813050.071
response to biotic stimulusGO:00096072940.065
phosphorylationGO:00163102940.064
organonitrogen compound metabolic processGO:19015643180.063
response to abiotic stimulusGO:00096283410.059
response to other organismGO:00517072930.058
response to external biotic stimulusGO:00432072930.057
intracellular signal transductionGO:00355563000.048
Mouse
actin filament based processGO:00300292200.048
compound eye developmentGO:00487493070.047
catabolic processGO:00090564090.046
chromosome organizationGO:00512763600.043
regulation of catalytic activityGO:00507901850.042
post embryonic appendage morphogenesisGO:00351203850.041
imaginal disc derived appendage morphogenesisGO:00351143950.041
single organism biosynthetic processGO:00447112060.040
appendage developmentGO:00487364010.040
response to bacteriumGO:00096171980.040
defense responseGO:00069523000.038
regulation of intracellular signal transductionGO:19025312360.038
carbohydrate derivative metabolic processGO:19011352170.034
neurological system processGO:00508773580.034
single organism behaviorGO:00447083910.033
establishment of localization in cellGO:00516494020.032
organic acid metabolic processGO:00060821030.030
programmed cell deathGO:00125012570.030
Mouse
negative regulation of phosphorus metabolic processGO:0010563450.029
imaginal disc derived wing morphogenesisGO:00074763370.029
protein phosphorylationGO:00064681690.029
immune system processGO:00023763470.029
mapk cascadeGO:00001651070.029
regulation of phosphorus metabolic processGO:00511742100.029
positive regulation of nitrogen compound metabolic processGO:00511733540.029
Mouse
positive regulation of signal transductionGO:00099672230.029
Mouse
homeostatic processGO:00425921990.028
wing disc morphogenesisGO:00074723440.028
positive regulation of catalytic activityGO:00430851180.028
organic substance catabolic processGO:19015753080.028
transcription from rna polymerase ii promoterGO:00063663680.027
Mouse
cellular catabolic processGO:00442483720.027
regulation of cell deathGO:00109411730.027
Mouse
response to extracellular stimulusGO:00099911160.027
immune responseGO:00069552460.026
negative regulation of cellular metabolic processGO:00313243820.026
dephosphorylationGO:0016311510.026
eye developmentGO:00016543230.026
regulation of transcription from rna polymerase ii promoterGO:00063573780.026
Mouse
defense response to other organismGO:00985422250.025
positive regulation of signalingGO:00230562430.025
Mouse
vesicle mediated transportGO:00161923810.024
proteolysisGO:00065081920.024
actin filament organizationGO:00070151260.024
positive regulation of phosphorus metabolic processGO:00105621390.024
protein localizationGO:00081042840.023
signal transduction by phosphorylationGO:00230141070.023
rna processingGO:00063961470.023
single organism catabolic processGO:00447122280.023
regulation of molecular functionGO:00650092170.023
regulation of hydrolase activityGO:0051336970.023
eye morphogenesisGO:00485922600.023
negative regulation of cell communicationGO:00106482230.023
Human
negative regulation of gene expressionGO:00106293870.023
organonitrogen compound catabolic processGO:19015651280.021
sensory perceptionGO:00076001960.021
carboxylic acid metabolic processGO:0019752920.021
imaginal disc derived appendage developmentGO:00487373990.021
cellular macromolecule localizationGO:00707272200.020
negative regulation of signal transductionGO:00099682060.020
Human
sensory organ morphogenesisGO:00905962600.020
regulation of cellular protein metabolic processGO:00322682430.020
regulation of cellular amine metabolic processGO:003323830.020
oocyte differentiationGO:00099941450.019
purine ribonucleotide metabolic processGO:00091501450.019
positive regulation of molecular functionGO:00440931360.019
regulation of mapk cascadeGO:0043408920.019
ion transportGO:00068111450.019
cell deathGO:00082192790.019
Mouse
sensory perception of chemical stimulusGO:00076061160.019
regulation of phosphate metabolic processGO:00192202100.019
positive regulation of cell deathGO:0010942690.019
Mouse
positive regulation of cell communicationGO:00106472500.018
Mouse
organic substance transportGO:00717022570.018
appendage morphogenesisGO:00351073970.018
oxoacid metabolic processGO:00434361030.018
actin cytoskeleton organizationGO:00300362060.018
negative regulation of phosphate metabolic processGO:0045936450.018
response to organophosphorusGO:004668320.018
response to oxygen containing compoundGO:19017002000.018
positive regulation of response to stimulusGO:00485843230.017
Mouse
regionalizationGO:00030024160.017
germarium derived egg chamber formationGO:00072931010.017
defense response to bacteriumGO:00427421780.017
positive regulation of phosphate metabolic processGO:00459371390.017
taxisGO:00423303040.017
response to organic substanceGO:00100332840.017
Human Mouse
cellular response to chemical stimulusGO:00708871990.017
Human Mouse
response to nutrient levelsGO:00316671140.017
carbohydrate derivative biosynthetic processGO:1901137850.017
synaptic transmissionGO:00072682880.017
cellular amino acid metabolic processGO:0006520610.017
metal ion transportGO:0030001740.017
negative regulation of cellular protein metabolic processGO:0032269850.016
small gtpase mediated signal transductionGO:0007264880.016
embryonic development via the syncytial blastodermGO:00017001480.016
regulation of programmed cell deathGO:00430671520.016
Mouse
secondary metabolic processGO:0019748750.016
endocytosisGO:00068973100.016
xenobiotic catabolic processGO:004217810.016
regulation of small gtpase mediated signal transductionGO:0051056930.016
regulation of cell cycleGO:00517262910.016
ribose phosphate metabolic processGO:00196931450.016
nuclear divisionGO:00002803320.015
regulation of phosphorylationGO:00423251470.015
phagocytosisGO:00069092150.015
positive regulation of biosynthetic processGO:00098913160.015
Mouse
innate immune responseGO:00450871440.015
male gamete generationGO:00482322010.015
macromolecule catabolic processGO:00090571610.015
organelle assemblyGO:00709251980.015
positive regulation of nucleobase containing compound metabolic processGO:00459353320.015
Mouse
muscle organ developmentGO:00075171270.015
regulation of proteolysisGO:0030162870.015
compound eye morphogenesisGO:00017452490.014
steroid catabolic processGO:000670610.014
cellular ketone metabolic processGO:0042180240.014
purine containing compound metabolic processGO:00725211550.014
regulation of endopeptidase activityGO:0052548360.014
negative regulation of protein metabolic processGO:0051248850.014
regulation of anatomical structure sizeGO:00900661630.013
organelle fissionGO:00482853400.013
nitrogen compound transportGO:0071705850.013
dendrite morphogenesisGO:00488131990.013
regulation of protein metabolic processGO:00512462560.013
aromatic compound catabolic processGO:00194391660.013
purine ribonucleotide catabolic processGO:00091541090.013
regulation of cellular component biogenesisGO:00440872010.013
segmentationGO:00352822070.013
ribonucleoside triphosphate catabolic processGO:00092031080.013
salivary gland morphogenesisGO:00074351450.013
cellular response to dna damage stimulusGO:00069742230.013
positive regulation of hydrolase activityGO:0051345780.013
deathGO:00162652840.013
Mouse
exocrine system developmentGO:00352721620.013
protein transportGO:00150311550.013
membrane organizationGO:00610241120.013
spermatogenesisGO:00072832000.013
heart processGO:0003015370.013
regulation of cellular ketone metabolic processGO:001056530.013
organic cyclic compound catabolic processGO:19013611680.012
negative regulation of signalingGO:00230572190.012
Human
macromolecular complex assemblyGO:00650032560.012
secretionGO:00469031090.012
neuromuscular junction developmentGO:00075281490.012
cellular nitrogen compound catabolic processGO:00442701650.012
nucleoside phosphate catabolic processGO:19012921100.012
regulation of notch signaling pathwayGO:00085931000.012
anatomical structure homeostasisGO:0060249970.012
regulation of localizationGO:00328792750.012
positive regulation of gene expressionGO:00106282900.012
Mouse
negative regulation of cell cycleGO:00457861160.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
cellular homeostasisGO:0019725800.012
regulation of organelle organizationGO:00330431960.012
purine nucleotide metabolic processGO:00061631460.012
camera type eye developmentGO:004301040.012
muscle structure developmentGO:00610612240.012
regulation of nervous system developmentGO:00519602480.012
erk1 and erk2 cascadeGO:0070371390.012
defense response to gram negative bacteriumGO:0050829940.012
regulation of cell cycle processGO:00105641810.011
regulation of immune system processGO:00026821760.011
gene silencingGO:00164581380.011
response to endogenous stimulusGO:00097191190.011
Human Mouse
salivary gland developmentGO:00074311620.011
gland morphogenesisGO:00226121450.011
apoptotic processGO:00069151590.011
Mouse
carbohydrate derivative catabolic processGO:19011361180.011
nucleotide metabolic processGO:00091171610.011
regulation of purine nucleotide metabolic processGO:1900542620.011
heterocycle catabolic processGO:00467001660.011
positive regulation of mapk cascadeGO:0043410630.011
positive regulation of intracellular signal transductionGO:19025331160.011
lipid metabolic processGO:00066291210.011
response to lipopolysaccharideGO:003249640.011
gland developmentGO:00487321910.011
negative regulation of nervous system developmentGO:0051961920.011
regulation of ras protein signal transductionGO:0046578930.011
response to temperature stimulusGO:00092661060.011
organonitrogen compound biosynthetic processGO:19015661170.011
embryonic pattern specificationGO:00098801740.011
peptidyl amino acid modificationGO:00181931050.011
protein modification by small protein conjugationGO:0032446790.011
dorsal ventral pattern formationGO:00099531330.011
covalent chromatin modificationGO:00165691060.011
regulation of transferase activityGO:0051338580.011
meiotic cell cycle processGO:19030461320.011
nucleobase containing compound catabolic processGO:00346551650.011
sensory perception of painGO:001923340.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
rna localizationGO:00064031150.011
adult behaviorGO:00305341370.011
response to hexoseGO:000974630.010
salivary gland histolysisGO:0035070880.010
regulation of cellular amino acid metabolic processGO:000652100.010
negative regulation of developmental processGO:00510932010.010
sensory perception of smellGO:0007608800.010
positive regulation of cellular biosynthetic processGO:00313283160.010
Mouse
regulation of mitotic cell cycleGO:00073461900.010
insecticide catabolic processGO:004670110.010
histone modificationGO:00165701060.010
vitamin metabolic processGO:000676620.010
cellular lipid metabolic processGO:0044255830.010

Wwox disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
cardiovascular system diseaseDOID:128700.028
vascular diseaseDOID:17800.015
artery diseaseDOID:005082800.015
nervous system diseaseDOID:86300.015
hypertensionDOID:1076300.011
central nervous system diseaseDOID:33100.010