Drosophila melanogaster

146 known processes

htl (Dmel_CG7223)

heartless

(Aliases: DmHD-38,DFGF-R2,DFGF-R1,Dmel\CG7223,DPR3,dtk1,DFR-1,FR1,FGF-R2,i150,Tk1,HTL/FGFR1,Dtk1,FGFR,j372,EMS2,DFR1/DFGF-R2,CT39172,DTRK(FR1),DFR1,Fr1,FGFR2,i79,CG7223,Dfr1,CT22273,Htl,Dfr-1,HD-38,i100)

htl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle structure developmentGO:00610612240.999
muscle attachmentGO:0016203360.997
mesoderm developmentGO:0007498780.997
cell migrationGO:00164772380.996
glial cell migrationGO:0008347310.991
skeletal muscle organ developmentGO:0060538480.987
muscle organ developmentGO:00075171270.986
cell motilityGO:00488702510.985
localization of cellGO:00516742570.981
gliogenesisGO:0042063800.978
tube developmentGO:00352952440.971
nephrocyte differentiationGO:0061319120.971
mesoderm morphogenesisGO:0048332220.969
regulation of cell developmentGO:00602842150.967
Human Mouse Rat Fly
regulation of multicellular organismal developmentGO:20000264140.962
Human Zebrafish Mouse Rat Fly
myoblast fusionGO:0007520430.946
neuron projection guidanceGO:00974852410.937
Worm
chemotaxisGO:00069352490.936
Worm
imaginal disc derived appendage morphogenesisGO:00351143950.932
axonogenesisGO:00074092900.926
Mouse Worm Fly
regulation of neurogenesisGO:00507671580.922
Human Mouse Rat Fly
embryonic organ developmentGO:0048568500.917
Human Mouse
regulation of phosphorus metabolic processGO:00511742100.908
Human Mouse Rat Fly
heart developmentGO:0007507820.906
larval visceral muscle developmentGO:000752390.906
mesoderm formationGO:0001707210.902
muscle cell differentiationGO:00426921030.887
embryonic morphogenesisGO:00485982060.866
pericardial nephrocyte differentiationGO:006132090.849
tube morphogenesisGO:00352391910.810
urogenital system developmentGO:0001655720.788
formation of primary germ layerGO:0001704240.786
tissue morphogenesisGO:00487292970.781
mesodermal cell fate commitmentGO:000171070.779
embryonic heart tube developmentGO:0035050220.778
renal filtration cell differentiationGO:0061318120.775
developmental growth involved in morphogenesisGO:0060560650.770
Mouse Fly
appendage morphogenesisGO:00351073970.769
Mouse
enzyme linked receptor protein signaling pathwayGO:00071671790.760
Human Zebrafish Mouse Rat Worm
regulation of phosphate metabolic processGO:00192202100.754
Human Mouse Rat Fly
cellular protein modification processGO:00064644380.748
Human Zebrafish Mouse Rat Worm Fly
glial cell developmentGO:0021782270.732
Mouse
cellular response to chemical stimulusGO:00708871990.730
Human Zebrafish Mouse Rat Worm
multi organism behaviorGO:00517051750.728
Worm
protein modification processGO:00362114380.718
Human Zebrafish Mouse Rat Worm Fly
phosphorylationGO:00163102940.714
Human Zebrafish Mouse Rat Worm Fly
wing disc morphogenesisGO:00074723440.714
appendage developmentGO:00487364010.707
Mouse
circulatory system developmentGO:0072359820.706
epithelial cell migrationGO:00106311480.699
Fly
positive regulation of molecular functionGO:00440931360.696
Human Fly
larval somatic muscle developmentGO:0007526190.684
cardiovascular system developmentGO:0072358820.683
syncytium formation by plasma membrane fusionGO:0000768430.674
positive regulation of phosphate metabolic processGO:00459371390.647
Human Mouse Rat Fly
ameboidal type cell migrationGO:00016671510.647
post embryonic appendage morphogenesisGO:00351203850.641
synapse organizationGO:00508081960.628
Mouse
growthGO:00400073590.628
Zebrafish Mouse Fly
synaptic growth at neuromuscular junctionGO:00511241190.627
regulation of neuron differentiationGO:00456641030.626
Human Mouse Rat Fly
intracellular signal transductionGO:00355563000.612
Human Mouse Rat Fly
positive regulation of nervous system developmentGO:0051962690.601
Human Mouse Rat
cardiocyte differentiationGO:0035051290.597
stem cell differentiationGO:00488631170.585
renal system developmentGO:0072001720.557
imaginal disc derived wing morphogenesisGO:00074763370.551
motor neuron axon guidanceGO:0008045580.547
amine metabolic processGO:0009308120.542
positive regulation of nitrogen compound metabolic processGO:00511733540.531
Human Mouse Rat
digestive tract developmentGO:00485651490.529
cell adhesionGO:00071551360.522
striated muscle cell differentiationGO:0051146900.505
actin cytoskeleton organizationGO:00300362060.504
regulation of cell cell adhesionGO:0022407210.494
positive regulation of macromolecule metabolic processGO:00106044050.487
Human Mouse Rat Fly
developmental growthGO:00485892800.480
Zebrafish Mouse Fly
cardioblast differentiationGO:0010002200.479
regulation of nervous system developmentGO:00519602480.476
Human Mouse Rat Fly
organic acid metabolic processGO:00060821030.474
Human Mouse
regulation of cell differentiationGO:00455953020.468
Human Zebrafish Mouse Rat Fly
morphogenesis of embryonic epitheliumGO:0016331940.463
Mouse
mesodermal cell differentiationGO:004833370.463
regulation of transcription from rna polymerase ii promoterGO:00063573780.461
Mouse Rat
protein phosphorylationGO:00064681690.459
Human Zebrafish Mouse Rat Worm Fly
gastrulationGO:0007369700.457
compound eye developmentGO:00487493070.445
regulation of phosphorylationGO:00423251470.444
Human Mouse Rat Fly
regulation of protein metabolic processGO:00512462560.443
Human Mouse Fly
heart morphogenesisGO:0003007320.443
Mouse
synapse assemblyGO:00074161430.441
negative regulation of macromolecule biosynthetic processGO:00105582700.435
Mouse
regulation of protein modification processGO:00313991120.434
Human Mouse Fly
regulation of phosphatidylinositol 3 kinase activityGO:004355120.433
Human
regulation of cellular protein metabolic processGO:00322682430.425
Human Mouse Fly
regulation of anatomical structure morphogenesisGO:00226032420.424
imaginal disc derived appendage developmentGO:00487373990.424
cellular amine metabolic processGO:0044106120.423
cell migration involved in gastrulationGO:004207490.419
positive regulation of phosphorus metabolic processGO:00105621390.414
Human Mouse Rat Fly
connective tissue developmentGO:006144830.414
Mouse
gland morphogenesisGO:00226121450.413
Mouse
skeletal muscle fiber developmentGO:004874130.410
neurological system processGO:00508773580.408
Mouse Rat
oocyte developmentGO:00485991240.404
actin filament based processGO:00300292200.404
regulation of synaptic growth at neuromuscular junctionGO:0008582890.390
dorsal closureGO:0007391790.388
regulation of cellular amino acid metabolic processGO:000652100.383
regulation of intracellular signal transductionGO:19025312360.383
Human Mouse Rat Fly
single organismal cell cell adhesionGO:0016337450.379
neuromuscular junction developmentGO:00075281490.378
Mouse
bmp signaling pathwayGO:0030509270.377
kidney developmentGO:000182230.372
Mouse
axon developmentGO:00615642970.372
Mouse Worm Fly
cellular lipid metabolic processGO:0044255830.371
Human
syncytium formationGO:0006949430.366
single organism biosynthetic processGO:00447112060.365
Human Mouse
salivary gland developmentGO:00074311620.362
Mouse
regulation of cellular ketone metabolic processGO:001056530.362
Human Mouse
nephron developmentGO:007200630.351
cell fate specificationGO:0001708710.350
Zebrafish Mouse Fly
regulation of developmental growthGO:00486381740.349
Mouse Fly
oocyte differentiationGO:00099941450.347
taxisGO:00423303040.345
Worm
digestive tract morphogenesisGO:00485461270.341
purine containing compound metabolic processGO:00725211550.339
positive regulation of gliogenesisGO:001401550.336
regulation of reproductive processGO:2000241540.332
Mouse
embryonic development via the syncytial blastodermGO:00017001480.329
negative regulation of nucleobase containing compound metabolic processGO:00459342610.325
Mouse
axon guidanceGO:00074112330.324
Worm
visceral muscle developmentGO:0007522140.320
regulation of peptidyl tyrosine phosphorylationGO:0050730100.318
Human Mouse
response to organic substanceGO:00100332840.315
Human Zebrafish Mouse Rat Worm
organonitrogen compound metabolic processGO:19015643180.310
regulation of mapk cascadeGO:0043408920.309
Human Mouse Rat Fly
small molecule metabolic processGO:00442813050.300
Human Mouse
glial cell differentiationGO:0010001350.298
regulation of organ morphogenesisGO:2000027780.298
Mouse
anatomical structure homeostasisGO:0060249970.297
Zebrafish
myotube cell developmentGO:001490430.291
regulation of cellular catabolic processGO:00313291570.289
determination of muscle attachment siteGO:001620470.284
digestive system developmentGO:00551231490.282
transmembrane transportGO:00550851390.281
oxoacid metabolic processGO:00434361030.281
Human Mouse
regulation of synapse structure and activityGO:00508031280.278
epidermal growth factor receptor signaling pathwayGO:0007173580.277
regulation of cellular amine metabolic processGO:003323830.269
cellular response to amino acid stimulusGO:007123060.267
regulation of erbb signaling pathwayGO:1901184420.262
cellular amino acid metabolic processGO:0006520610.255
regulation of localizationGO:00328792750.253
somatic muscle developmentGO:0007525660.252
regulation of epithelial cell proliferationGO:005067840.249
Mouse Rat
signal transduction by phosphorylationGO:00230141070.249
Human Mouse Rat Fly
endodermal cell differentiationGO:003598730.245
regulation of catabolic processGO:00098941700.242
positive regulation of cellular component organizationGO:00511301560.240
Mouse Rat
embryonic pattern specificationGO:00098801740.240
Mouse
positive regulation of phagocytosisGO:005076630.237
positive regulation of cell proliferationGO:0008284470.236
Human Mouse Rat
glycosyl compound catabolic processGO:19016581120.233
positive regulation of protein metabolic processGO:00512471280.232
Human Mouse Fly
single organism cell adhesionGO:0098602470.231
head developmentGO:00603221350.230
Zebrafish Mouse Rat
positive regulation of glial cell proliferationGO:006025250.230
sex differentiationGO:0007548810.226
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.223
Human Zebrafish Mouse Rat Worm
tissue migrationGO:00901301550.219
response to fibroblast growth factorGO:0071774100.219
Human Zebrafish Mouse Rat Worm
positive regulation of cellular amine metabolic processGO:003324000.215
determination of bilateral symmetryGO:0009855130.213
Zebrafish
regulation of cell proliferationGO:00421271630.211
Human Mouse Rat
regulation of actin filament based processGO:0032970420.210
positive regulation of phosphorylationGO:0042327870.209
Human Mouse Rat Fly
regulation of cellular component biogenesisGO:00440872010.206
extracellular structure organizationGO:0043062460.205
Human
wnt signaling pathwayGO:0016055980.203
Mouse
regulation of cell projection organizationGO:0031344920.200
Mouse Rat Worm Fly
immune responseGO:00069552460.200
cellular protein localizationGO:00346131600.194
negative regulation of cell differentiationGO:00455961430.192
Zebrafish Mouse Rat Fly
endodermal cell fate commitmentGO:000171130.190
positive regulation of cellular catabolic processGO:0031331950.188
negative regulation of erbb signaling pathwayGO:1901185290.188
organ formationGO:0048645390.186
Mouse
negative regulation of nervous system developmentGO:0051961920.183
Mouse Fly
carboxylic acid metabolic processGO:0019752920.182
Human Mouse
developmental maturationGO:00217001720.181
Mouse
peripheral nervous system developmentGO:0007422520.180
blood circulationGO:0008015260.179
negative regulation of rna biosynthetic processGO:19026792400.178
Mouse
negative regulation of response to stimulusGO:00485852580.177
Mouse
sensory perception of mechanical stimulusGO:0050954720.177
Mouse
ovipositionGO:0018991190.173
Worm
cellular component assembly involved in morphogenesisGO:00109271510.172
Zebrafish
regulation of molecular functionGO:00650092170.170
Human Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.169
Human Mouse Rat
positive regulation of muscle organ developmentGO:004863660.168
Mouse
positive regulation of biosynthetic processGO:00098913160.167
Human Mouse Rat
myotube differentiationGO:0014902460.166
positive regulation of cellular component biogenesisGO:0044089800.164
regulation of synapse assemblyGO:0051963940.162
ribonucleotide metabolic processGO:00092591450.161
multi multicellular organism processGO:00447061230.160
Worm
activation of rac gtpase activityGO:003286330.160
transcription from rna polymerase ii promoterGO:00063663680.159
Mouse Rat
embryonic hemopoiesisGO:0035162260.159
purine nucleoside metabolic processGO:00422781270.157
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.156
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.155
Mouse Rat
chromatin organizationGO:00063252070.155
negative regulation of cellular component organizationGO:00511291080.154
Mouse Fly
malpighian tubule developmentGO:0072002640.153
positive regulation of cellular biosynthetic processGO:00313283160.152
Human Mouse Rat
cell chemotaxisGO:006032660.152
actin filament bundle organizationGO:0061572280.151
positive regulation of transcription dna templatedGO:00458932660.151
Mouse Rat
regulation of cellular component movementGO:0051270420.149
muscle fiber developmentGO:0048747120.149
positive regulation of response to stimulusGO:00485843230.148
germ cell migrationGO:0008354430.139
specification of symmetryGO:0009799130.139
Zebrafish
positive regulation of cell communicationGO:00106472500.139
Human Mouse Rat Fly
cell fate commitment involved in formation of primary germ layerGO:0060795100.138
positive regulation of multicellular organismal processGO:00512401430.137
Human Mouse Rat
positive regulation of cellular amino acid metabolic processGO:004576400.137
response to oxygen containing compoundGO:19017002000.136
kidney epithelium developmentGO:007207330.136
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.136
negative regulation of biosynthetic processGO:00098902770.135
Mouse
cell fate determinationGO:0001709910.135
morphogenesis of a polarized epitheliumGO:0001738930.135
regulation of stress fiber assemblyGO:005149260.134
regulation of apoptotic processGO:00429811300.133
Mouse
salivary gland morphogenesisGO:00074351450.132
Mouse
regulation of catalytic activityGO:00507901850.130
Human Fly
positive regulation of nucleic acid templated transcriptionGO:19035082660.128
Mouse Rat
positive regulation of cell developmentGO:0010720610.128
Human Mouse Rat
formation of anatomical boundaryGO:0048859370.128
defense responseGO:00069523000.128
digestive tract mesoderm developmentGO:000750250.125
regulation of small gtpase mediated signal transductionGO:0051056930.125
skeletal muscle tissue developmentGO:0007519130.122
cation homeostasisGO:0055080510.122
formation of organ boundaryGO:0010160300.121
camera type eye morphogenesisGO:004859320.121
Mouse
regulation of actin cytoskeleton organizationGO:0032956420.119
striated muscle tissue developmentGO:0014706270.118
Zebrafish Mouse
actin filament organizationGO:00070151260.116
nucleobase containing small molecule metabolic processGO:00550861740.116
cellular ketone metabolic processGO:0042180240.115
Human Mouse
cardiac cell fate commitmentGO:0060911170.115
ion transmembrane transportGO:00342201220.114
rhythmic behaviorGO:0007622760.114
peptidyl tyrosine modificationGO:0018212240.114
Human Zebrafish Mouse Rat Fly
establishment of tissue polarityGO:0007164870.113
positive regulation of lipid metabolic processGO:004583440.112
Human
convergent extension involved in gastrulationGO:006002720.111
regulation of ras gtpase activityGO:0032318380.111
regulation of hydrolase activityGO:0051336970.110
Human
single organism behaviorGO:00447083910.110
multi organism reproductive behaviorGO:00447051210.110
Worm
positive regulation of hydrolase activityGO:0051345780.110
Human
actomyosin structure organizationGO:0031032560.109
negative regulation of cellular metabolic processGO:00313243820.109
Mouse
organelle assemblyGO:00709251980.108
Zebrafish
positive regulation of phagocytosis engulfmentGO:006010010.107
inositol lipid mediated signalingGO:004801740.107
negative regulation of transcription dna templatedGO:00458922370.107
Mouse
agingGO:00075681430.106
positive regulation of cell motilityGO:200014730.105
cellular response to oxygen containing compoundGO:1901701790.105
negative regulation of developmental processGO:00510932010.104
Zebrafish Mouse Rat Fly
epithelial cell morphogenesis involved in gastrulationGO:000338170.104
deathGO:00162652840.104
Human Mouse
nephron epithelium developmentGO:007200930.103
cgmp metabolic processGO:0046068110.102
regionalizationGO:00030024160.102
Zebrafish Mouse
body morphogenesisGO:001017120.101
ribose phosphate metabolic processGO:00196931450.099
cellular macromolecule localizationGO:00707272200.099
mesodermal cell migrationGO:000807870.099
negative regulation of rna metabolic processGO:00512532510.099
Mouse
biological adhesionGO:00226101380.098
regulation of epithelial cell migration open tracheal systemGO:2000274110.097
epithelium migrationGO:00901321480.096
Fly
cell maturationGO:00484691440.096
Mouse
regulation of synapse organizationGO:00508071100.095
renal filtrationGO:009720570.095
purine nucleotide metabolic processGO:00061631460.092
regulation of neuron projection developmentGO:0010975690.092
Mouse Rat Fly
regulation of cell growthGO:0001558430.092
Fly
negative regulation of protein phosphorylationGO:0001933170.091
response to growth factorGO:0070848310.091
Human Zebrafish Mouse Rat Worm
response to organonitrogen compoundGO:0010243750.091
purine ribonucleotide metabolic processGO:00091501450.091
homeostatic processGO:00425921990.091
Zebrafish Mouse
regulation of transferase activityGO:0051338580.090
Human Fly
positive regulation of behaviorGO:0048520190.090
morphogenesis of an epitheliumGO:00020092760.090
Zebrafish Mouse Fly
response to endogenous stimulusGO:00097191190.090
Human Zebrafish Mouse Rat Worm
oocyte maturationGO:000155630.090
segmentationGO:00352822070.090
cardiac cell fate determinationGO:006091330.089
neuron recognitionGO:00080381010.089
positive regulation of cell migrationGO:003033520.088
cardioblast cell fate determinationGO:000751030.088
ventral cord developmentGO:0007419160.087
negative regulation of phosphate metabolic processGO:0045936450.087
negative regulation of signalingGO:00230572190.084
Mouse
negative regulation of multicellular organismal processGO:00512411420.084
Zebrafish Mouse Rat Fly
nucleoside triphosphate metabolic processGO:00091411200.084
organophosphate metabolic processGO:00196371950.084
Human
regulation of response to stressGO:00801342000.084
activation of protein kinase activityGO:0032147120.083
Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.083
regulation of protein phosphorylationGO:0001932640.083
Human Mouse Fly
rho protein signal transductionGO:0007266140.083
regulation of cell motilityGO:2000145230.082
positive regulation of developmental processGO:00510941430.081
Human Mouse Rat
ion transportGO:00068111450.081
regulation of growthGO:00400082330.080
Mouse Fly
regulation of cellular component sizeGO:0032535980.080
Fly
cellular catabolic processGO:00442483720.079
regulation of epithelial cell migrationGO:0010632120.079
regulation of purine nucleotide metabolic processGO:1900542620.077
nucleotide metabolic processGO:00091171610.077
carbohydrate derivative metabolic processGO:19011352170.076
central nervous system developmentGO:00074172010.076
chorion containing eggshell formationGO:00073041050.075
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.074
Human Mouse
regulation of anatomical structure sizeGO:00900661630.074
Fly
cellular response to growth factor stimulusGO:0071363300.074
Human Zebrafish Mouse Rat Worm
cranial nerve developmentGO:002154510.074
Zebrafish
peptidyl amino acid modificationGO:00181931050.073
Human Zebrafish Mouse Rat Fly
regulation of wnt signaling pathwayGO:0030111680.073
Mouse
regulation of cell cycleGO:00517262910.072
Mouse
mesodermal cell fate specificationGO:000750120.072
Mouse
response to biotic stimulusGO:00096072940.072
regulation of protein kinase activityGO:0045859510.071
Human Fly
reproductive system developmentGO:0061458740.071
actin cytoskeleton reorganizationGO:0031532220.071
blastoderm segmentationGO:00073501590.071
cell cell signaling involved in cell fate commitmentGO:00451682100.070
Mouse
response to ethanolGO:0045471590.070
small gtpase mediated signal transductionGO:0007264880.068
camera type eye developmentGO:004301040.068
Mouse
forebrain developmentGO:003090020.067
Mouse Rat
regulation of locomotionGO:0040012420.067
regulation of cell migrationGO:0030334220.067
actin filament bundle assemblyGO:0051017260.067
pericardium morphogenesisGO:000334420.066
regulation of cell deathGO:00109411730.066
Mouse
nucleoside metabolic processGO:00091161270.065
positive regulation of protein complex assemblyGO:0031334220.065
epithelial cell migration open tracheal systemGO:0007427320.065
Fly
regulation of bmp signaling pathwayGO:0030510230.065
positive regulation of catabolic processGO:00098961050.064
reproductive structure developmentGO:0048608740.064
positive regulation of catalytic activityGO:00430851180.064
Human Fly
purine ribonucleoside metabolic processGO:00461281270.064
synaptic transmissionGO:00072682880.063
Mouse
cell proliferationGO:00082832990.063
Human Zebrafish Mouse Rat
associative learningGO:0008306650.063
larval heart developmentGO:000750860.062
regulation of cell morphogenesisGO:00226041630.062
inorganic cation transmembrane transportGO:0098662610.062
oocyte growthGO:000155550.062
cellular response to endogenous stimulusGO:0071495800.062
Human Zebrafish Mouse Rat Worm
cellular protein complex assemblyGO:0043623710.061
embryonic hindgut morphogenesisGO:0048619480.061
positive regulation of developmental growthGO:0048639620.061
Mouse
catabolic processGO:00090564090.061
Worm
nucleoside phosphate metabolic processGO:00067531620.059
sarcomere organizationGO:0045214260.059
negative regulation of phosphorus metabolic processGO:0010563450.059
regulation of glial cell proliferationGO:0060251110.058
regulation of muscle cell differentiationGO:005114780.058
Mouse
endoderm formationGO:000170630.058
protein complex assemblyGO:00064612000.057
renal tubule developmentGO:0061326640.057
regulation of kinase activityGO:0043549530.057
Human Fly
morphogenesis of a branching structureGO:0001763450.057
Mouse Fly
negative regulation of protein metabolic processGO:0051248850.057
positive regulation of growthGO:0045927750.056
Mouse
regulation of cellular localizationGO:00603411360.056
myofibril assemblyGO:0030239360.055
muscle cell developmentGO:0055001500.055
integrin mediated signaling pathwayGO:000722930.055
positive regulation of macromolecule biosynthetic processGO:00105572830.055
Human Mouse Rat
muscle organ morphogenesisGO:004864470.055
Mouse
response to radiationGO:00093141550.055
cell substrate adhesionGO:0031589100.055
garland nephrocyte differentiationGO:006132130.055
regulation of nucleotide metabolic processGO:0006140620.054
lymph gland developmentGO:0048542280.054
sensory perception of soundGO:0007605560.054
Mouse
stem cell divisionGO:0017145690.054
Mouse
reproductive behaviorGO:00190981220.053
Worm
circulatory system processGO:0003013370.053
negative regulation of kinase activityGO:0033673160.053
negative regulation of cellular biosynthetic processGO:00313272770.053
Mouse
peptidyl tyrosine phosphorylationGO:0018108240.053
Human Zebrafish Mouse Rat Fly
cognitionGO:00508901410.053
positive regulation of gene expressionGO:00106282900.053
Mouse Rat
positive regulation of cellular protein metabolic processGO:00322701180.052
Human Mouse Fly
eggshell formationGO:00307031050.052
protein localizationGO:00081042840.052
negative regulation of protein modification processGO:0031400290.050
mapk cascadeGO:00001651070.050
Human Mouse Rat Fly
positive regulation of rna biosynthetic processGO:19026802660.050
Mouse Rat
hematopoietic or lymphoid organ developmentGO:0048534570.050
cyclic nucleotide metabolic processGO:0009187280.050
muscle cell fate commitmentGO:0042693140.049
cellular response to organic substanceGO:00713101320.049
Human Zebrafish Mouse Rat Worm
cation transmembrane transportGO:0098655880.049
sensory organ morphogenesisGO:00905962600.049
Mouse
cellular homeostasisGO:0019725800.049
malpighian tubule morphogenesisGO:0007443440.049
telencephalon developmentGO:002153720.049
Rat
transmission of nerve impulseGO:0019226120.049
Mouse
metal ion transportGO:0030001740.048
open tracheal system developmentGO:00074242040.048
Fly
guanosine containing compound metabolic processGO:1901068740.048
muscle system processGO:0003012210.047
cell cell junction organizationGO:0045216550.047
embryonic axis specificationGO:00005781070.047
ribonucleoside triphosphate catabolic processGO:00092031080.047
internal protein amino acid acetylationGO:0006475380.047
hemocyte migrationGO:0035099190.047
torso signaling pathwayGO:0008293210.047
sensory perceptionGO:00076001960.046
Mouse Rat
regulation of notch signaling pathwayGO:00085931000.046
hindgut developmentGO:0061525580.046
regulation of lipid metabolic processGO:0019216150.046
Human Mouse
cellular response to nitrogen compoundGO:1901699510.046
tripartite regional subdivisionGO:00073511030.046
neuron deathGO:0070997270.046
Mouse
multicellular organismal homeostasisGO:0048871410.046
muscle cell migrationGO:001481230.045
optokinetic behaviorGO:000763430.045
negative regulation of growthGO:0045926840.045
Mouse Fly
hindgut morphogenesisGO:0007442580.045
negative regulation of cellular protein metabolic processGO:0032269850.045
regulation of transmembrane transporter activityGO:002289860.044
filopodium assemblyGO:0046847330.044
Fly
anterior posterior pattern specification imaginal discGO:0007448160.044
response to other organismGO:00517072930.044
regulation of nucleotide catabolic processGO:0030811480.044
positive regulation of rna metabolic processGO:00512542710.043
Mouse Rat
regulation of synaptic transmissionGO:0050804690.043
regulation of proteolysisGO:0030162870.043
Human
fusion cell fate specificationGO:003515640.043
regulation of chemotaxisGO:0050920120.043
erbb signaling pathwayGO:0038127580.043
eye antennal disc developmentGO:0035214600.042
purine ribonucleoside triphosphate metabolic processGO:00092051190.042
cell growthGO:00160491080.042
Fly
anterior malpighian tubule developmentGO:0061327120.042
regulation of nucleotide biosynthetic processGO:0030808140.042
response to nitrogen compoundGO:1901698900.041
heart contractionGO:0060047260.041
regulation of cell adhesionGO:0030155270.041
negative regulation of cell communicationGO:00106482230.040
Mouse
positive regulation of nucleotide metabolic processGO:0045981550.040
regulation of actin polymerization or depolymerizationGO:0008064270.040
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.040
neural precursor cell proliferationGO:0061351750.040
Zebrafish Mouse
optic lobe placode formationGO:000174440.040
axon midline choice point recognitionGO:0016199260.040
regulation of mitotic cell cycle phase transitionGO:19019901300.039
covalent chromatin modificationGO:00165691060.039
extrinsic apoptotic signaling pathwayGO:009719110.039
Human Mouse
regulation of organelle organizationGO:00330431960.039
Mouse
cellular response to fibroblast growth factor stimulusGO:0044344100.039
Human Zebrafish Mouse Rat Worm
response to light stimulusGO:00094161240.038
negative regulation of nitrogen compound metabolic processGO:00511722650.038
Mouse
multicellular organismal signalingGO:0035637120.038
Mouse
exocrine system developmentGO:00352721620.038
Mouse
striated muscle cell developmentGO:0055002500.038
nephron tubule morphogenesisGO:007207830.038
apposition of dorsal and ventral imaginal disc derived wing surfacesGO:0007475150.037
purine ribonucleoside catabolic processGO:00461301120.037

htl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.292
Human
seminomaDOID:444000.292
Human
germ cell cancerDOID:299400.292
Human
cancerDOID:16200.292
Human
cell type cancerDOID:005068700.292
Human
disease of anatomical entityDOID:700.184
Human
heart diseaseDOID:11400.095
tetralogy of fallotDOID:641900.095
cardiovascular system diseaseDOID:128700.095
Human
congenital heart diseaseDOID:168200.095