Drosophila melanogaster

58 known processes

Spn5 (Dmel_CG18525)

Serine protease inhibitor 5

(Aliases: Spn88Ea,Dmel\CG18525,Sp5,spn5,sp5,CG18525)

Spn5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune responseGO:00069552460.157
defense responseGO:00069523000.147
response to external biotic stimulusGO:00432072930.139
organonitrogen compound metabolic processGO:19015643180.116
cellular protein modification processGO:00064644380.110
regulation of defense responseGO:00313471020.099
response to bacteriumGO:00096171980.092
imaginal disc derived appendage developmentGO:00487373990.088
negative regulation of response to stimulusGO:00485852580.087
response to other organismGO:00517072930.087
endocytosisGO:00068973100.080
negative regulation of signalingGO:00230572190.080
response to biotic stimulusGO:00096072940.078
steroid catabolic processGO:000670610.078
regulation of protein metabolic processGO:00512462560.076
cell adhesionGO:00071551360.074
negative regulation of signal transductionGO:00099682060.073
defense response to bacteriumGO:00427421780.073
regulation of cellular protein metabolic processGO:00322682430.071
negative regulation of cell communicationGO:00106482230.064
vesicle mediated transportGO:00161923810.064
cellular amino acid metabolic processGO:0006520610.064
negative regulation of catalytic activityGO:0043086420.062
regulation of multi organism processGO:00439001310.059
regulation of cell projection organizationGO:0031344920.056
defense response to other organismGO:00985422250.056
negative regulation of cell developmentGO:0010721620.052
immune system processGO:00023763470.051
regionalizationGO:00030024160.051
homeostatic processGO:00425921990.049
defense response to fungusGO:0050832480.049
lateral inhibitionGO:00463312060.048
defense response to gram negative bacteriumGO:0050829940.047
innate immune responseGO:00450871440.047
phagocytosisGO:00069092150.047
regulation of neuron projection developmentGO:0010975690.046
regulation of catalytic activityGO:00507901850.046
cell cell signaling involved in cell fate commitmentGO:00451682100.046
response to abiotic stimulusGO:00096283410.045
amine metabolic processGO:0009308120.043
negative regulation of cellular component organizationGO:00511291080.042
protein maturationGO:0051604710.042
regulation of nervous system developmentGO:00519602480.040
appendage developmentGO:00487364010.040
negative regulation of cellular protein metabolic processGO:0032269850.040
regulation of cellular amine metabolic processGO:003323830.039
hormone metabolic processGO:0042445330.038
regulation of localizationGO:00328792750.037
regulation of neuron differentiationGO:00456641030.037
regulation of cell differentiationGO:00455953020.036
establishment of glial blood brain barrierGO:0060857140.036
biological adhesionGO:00226101380.036
cellular response to chemical stimulusGO:00708871990.036
response to lipopolysaccharideGO:003249640.036
organic acid metabolic processGO:00060821030.036
organic substance transportGO:00717022570.035
imaginal disc derived wing morphogenesisGO:00074763370.035
regulation of intracellular signal transductionGO:19025312360.035
oxoacid metabolic processGO:00434361030.034
humoral immune responseGO:00069591170.033
regulation of peptidase activityGO:0052547390.033
negative regulation of cellular metabolic processGO:00313243820.033
regulation of immune system processGO:00026821760.032
cellular response to hormone stimulusGO:0032870440.032
cellular ketone metabolic processGO:0042180240.032
regulation of response to biotic stimulusGO:0002831630.032
body morphogenesisGO:001017120.032
neurological system processGO:00508773580.032
response to fungusGO:0009620500.032
regulation of multicellular organismal developmentGO:20000264140.032
phosphorylationGO:00163102940.032
appendage morphogenesisGO:00351073970.031
negative regulation of protein metabolic processGO:0051248850.031
imaginal disc derived appendage morphogenesisGO:00351143950.031
regulation of response to external stimulusGO:00321011150.030
cell proliferationGO:00082832990.030
protein phosphorylationGO:00064681690.030
negative regulation of multicellular organismal processGO:00512411420.029
positive regulation of signalingGO:00230562430.029
antimicrobial humoral responseGO:0019730990.029
cellular amine metabolic processGO:0044106120.029
mapk cascadeGO:00001651070.029
forebrain developmentGO:003090020.029
response to woundingGO:0009611940.028
signal transduction by phosphorylationGO:00230141070.028
regulation of phosphorus metabolic processGO:00511742100.028
negative regulation of gene expressionGO:00106293870.028
regulation of cell developmentGO:00602842150.027
cellular response to endogenous stimulusGO:0071495800.027
cellular macromolecule localizationGO:00707272200.027
regulation of cellular amino acid metabolic processGO:000652100.027
regulation of neurogenesisGO:00507671580.027
wing disc morphogenesisGO:00074723440.027
negative regulation of neurogenesisGO:0050768530.027
glycosyl compound catabolic processGO:19016581120.026
regulation of immune responseGO:00507761180.026
protein processingGO:0016485680.026
regulation of mapk cascadeGO:0043408920.026
regulation of cellular ketone metabolic processGO:001056530.026
mushroom body developmentGO:0016319700.025
secretion by cellGO:00329401010.025
peptide metabolic processGO:0006518800.025
cation transportGO:00068121100.025
regulation of cell substrate adhesionGO:001081020.025
protein modification processGO:00362114380.024
regulation of hydrolase activityGO:0051336970.024
detection of stimulusGO:00516061560.024
proteolysisGO:00065081920.024
eye developmentGO:00016543230.024
cellular response to organic substanceGO:00713101320.024
establishment of localization in cellGO:00516494020.024
small molecule metabolic processGO:00442813050.024
positive regulation of cell communicationGO:00106472500.024
post embryonic appendage morphogenesisGO:00351203850.024
intracellular signal transductionGO:00355563000.023
single organism behaviorGO:00447083910.023
agingGO:00075681430.023
sensory perceptionGO:00076001960.023
regulation of proteolysisGO:0030162870.022
negative regulation of immune system processGO:0002683500.022
regulation of molecular functionGO:00650092170.021
signal releaseGO:0023061490.021
hormone catabolic processGO:004244730.021
peptidyl amino acid modificationGO:00181931050.021
programmed cell deathGO:00125012570.021
protein localizationGO:00081042840.021
negative regulation of developmental processGO:00510932010.021
response to organic substanceGO:00100332840.020
carboxylic acid metabolic processGO:0019752920.020
regulation of phosphate metabolic processGO:00192202100.020
ribonucleoside catabolic processGO:00424541120.020
negative regulation of nitrogen compound metabolic processGO:00511722650.020
negative regulation of molecular functionGO:0044092510.020
anatomical structure homeostasisGO:0060249970.019
cell deathGO:00082192790.019
chemotaxisGO:00069352490.019
open tracheal system developmentGO:00074242040.019
regulation of hormone levelsGO:0010817400.019
androgen metabolic processGO:000820910.018
immune response activating signal transductionGO:000275720.018
negative regulation of response to external stimulusGO:0032102220.018
cell cell junction organizationGO:0045216550.018
immune response regulating signaling pathwayGO:000276420.018
organic cyclic compound catabolic processGO:19013611680.018
neuron projection guidanceGO:00974852410.017
camera type eye developmentGO:004301040.017
ion transportGO:00068111450.017
positive regulation of response to stimulusGO:00485843230.017
regulation of tube size open tracheal systemGO:0035151430.017
regulation of cellular localizationGO:00603411360.017
actin cytoskeleton organizationGO:00300362060.016
regulation of cell adhesionGO:0030155270.016
developmental programmed cell deathGO:00106231380.016
embryonic pattern specificationGO:00098801740.016
deathGO:00162652840.016
antifungal humoral responseGO:0019732120.016
aromatic compound catabolic processGO:00194391660.016
axis specificationGO:00097981670.016
actin filament based processGO:00300292200.016
telencephalon developmentGO:002153720.016
central nervous system developmentGO:00074172010.016
cellular protein localizationGO:00346131600.016
growthGO:00400073590.016
g protein coupled receptor signaling pathwayGO:00071861360.015
ras protein signal transductionGO:0007265880.015
regulation of cell proliferationGO:00421271630.015
response to nutrient levelsGO:00316671140.015
taxisGO:00423303040.015
regulation of protein modification processGO:00313991120.015
regulation of membrane potentialGO:0042391350.015
negative regulation of nervous system developmentGO:0051961920.015
kidney developmentGO:000182230.015
compound eye developmentGO:00487493070.015
negative regulation of cell differentiationGO:00455961430.015
nitrogen compound transportGO:0071705850.015
substrate adhesion dependent cell spreadingGO:003444620.015
head developmentGO:00603221350.015
regulation of cell morphogenesis involved in differentiationGO:0010769610.015
cell cycle phase transitionGO:00447701400.015
tube developmentGO:00352952440.015
carbohydrate derivative metabolic processGO:19011352170.014
negative regulation of protein processingGO:0010955310.014
negative regulation of defense responseGO:0031348350.014
regulation of protein serine threonine kinase activityGO:0071900250.014
regulation of antimicrobial humoral responseGO:0002759500.014
ribonucleotide metabolic processGO:00092591450.014
cell cell junction assemblyGO:0007043380.014
negative regulation of phosphate metabolic processGO:0045936450.014
response to endogenous stimulusGO:00097191190.014
response to hormoneGO:0009725450.014
wound healingGO:0042060750.014
tissue morphogenesisGO:00487292970.014
nucleoside triphosphate catabolic processGO:00091431080.014
segmentationGO:00352822070.014
cuticle developmentGO:0042335860.014
cellular catabolic processGO:00442483720.014
tube morphogenesisGO:00352391910.014
respiratory system developmentGO:00605412130.014
lipid metabolic processGO:00066291210.014
regulation of cell morphogenesisGO:00226041630.013
multicellular organismal agingGO:00102591400.013
chemical homeostasisGO:0048878920.013
developmental maturationGO:00217001720.013
chitin based cuticle sclerotizationGO:0007593190.013
small gtpase mediated signal transductionGO:0007264880.013
regulation of phosphorylationGO:00423251470.013
regulation of protein processingGO:0070613320.013
catabolic processGO:00090564090.013
regulation of catabolic processGO:00098941700.013
embryonic axis specificationGO:00005781070.013
extracellular structure organizationGO:0043062460.013
regulation of anatomical structure morphogenesisGO:00226032420.013
regulation of secretionGO:0051046440.013
positive regulation of signal transductionGO:00099672230.013
carbohydrate metabolic processGO:0005975820.013
activation of innate immune responseGO:000221840.013
detection of external stimulusGO:0009581660.013
nucleoside phosphate catabolic processGO:19012921100.013
positive regulation of cell motilityGO:200014730.013
positive regulation of transportGO:0051050920.012
single organism cell adhesionGO:0098602470.012
nucleoside phosphate metabolic processGO:00067531620.012
response to oxygen containing compoundGO:19017002000.012
developmental growthGO:00485892800.012
dendrite developmentGO:00163582040.012
embryonic morphogenesisGO:00485982060.012
regulation of response to stressGO:00801342000.012
cellular response to molecule of bacterial originGO:007121930.012
response to copper ionGO:004668840.012
organic substance catabolic processGO:19015753080.012
single organism biosynthetic processGO:00447112060.012
nucleoside catabolic processGO:00091641120.012
glycoprotein metabolic processGO:0009100410.012
apical junction assemblyGO:0043297320.012
cellular cation homeostasisGO:0030003380.011
mesenchymal cell developmentGO:001403110.011
heterocycle catabolic processGO:00467001660.011
regulation of secretion by cellGO:1903530390.011
cellular response to lipopolysaccharideGO:007122230.011
regulation of cellular catabolic processGO:00313291570.011
single organism catabolic processGO:00447122280.011
adult behaviorGO:00305341370.011
salivary gland developmentGO:00074311620.011
regulation of tube architecture open tracheal systemGO:0035152680.011
regulation of cell deathGO:00109411730.011
positive regulation of intracellular signal transductionGO:19025331160.011
cell junction organizationGO:0034330570.011
positive regulation of cellular component biogenesisGO:0044089800.011
positive regulation of catalytic activityGO:00430851180.011
embryo development ending in birth or egg hatchingGO:00097921520.011
regenerationGO:0031099160.011
organophosphate catabolic processGO:00464341120.011
establishment of blood brain barrierGO:0060856160.011
determination of adult lifespanGO:00083401370.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
purine nucleotide metabolic processGO:00061631460.011
regulation of immune effector processGO:0002697520.011
cell motilityGO:00488702510.011
negative regulation of proteolysisGO:0045861310.010
regulation of growthGO:00400082330.010
purine nucleoside catabolic processGO:00061521120.010
detection of abiotic stimulusGO:0009582660.010
spinal cord developmentGO:002151010.010
nucleoside metabolic processGO:00091161270.010
olfactory behaviorGO:0042048970.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
cellular nitrogen compound catabolic processGO:00442701650.010
nucleotide metabolic processGO:00091171610.010
response to organonitrogen compoundGO:0010243750.010
synaptic transmissionGO:00072682880.010
chemosensory behaviorGO:00076351060.010
hormone mediated signaling pathwayGO:0009755160.010
dephosphorylationGO:0016311510.010
response to starvationGO:0042594970.010

Spn5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.051
nervous system diseaseDOID:86300.015
disease of metabolismDOID:001466700.013
sensory system diseaseDOID:005015500.012
connective tissue diseaseDOID:6500.010
musculoskeletal system diseaseDOID:1700.010
eye and adnexa diseaseDOID:149200.010
kidney diseaseDOID:55700.010
renal tubular transport diseaseDOID:44700.010
urinary system diseaseDOID:1800.010