IMP: Integrative Multi-species Prediction

Drosophila melanogaster

67 known processes

Ntl (Dmel_CG7075)

Neurotransmitter transporter-like

(Aliases: Dmel\CG7075,CG7075,ntl)

FLYBASE: FBgn0031934
Entrez: 34046
UniProtKB: Q8IPH3
UniProtKB: Q9VLY6

Process Predictions
Disease Predictions

Ntl biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
sperm motility	GO:0030317	12	0.533
localization of cell	GO:0051674	257	0.074
organelle assembly	GO:0070925	198	0.073
organonitrogen compound metabolic process	GO:1901564	318	0.063
cell motility	GO:0048870	251	0.061
regionalization	GO:0003002	416	0.042
protein complex assembly	GO:0006461	200	0.041
macromolecular complex assembly	GO:0065003	256	0.037
chromosome organization	GO:0051276	360	0.036
cilium morphogenesis	GO:0060271	39	0.036
transmembrane transport	GO:0055085	139	0.034
amine metabolic process	GO:0009308	12	0.034
cellular amino acid metabolic process	GO:0006520	61	0.033
regulation of protein metabolic process	GO:0051246	256	0.033
microtubule organizing center organization	GO:0031023	168	0.033
cell division	GO:0051301	248	0.032
cellular ketone metabolic process	GO:0042180	24	0.032
response to bacterium	GO:0009617	198	0.032
vesicle mediated transport	GO:0016192	381	0.031	Fly
exocrine system development	GO:0035272	162	0.030
positive regulation of response to stimulus	GO:0048584	323	0.029
response to abiotic stimulus	GO:0009628	341	0.029	Fly
post embryonic appendage morphogenesis	GO:0035120	385	0.029
death	GO:0016265	284	0.029
oxoacid metabolic process	GO:0043436	103	0.028
centrosome organization	GO:0051297	163	0.028
gland morphogenesis	GO:0022612	145	0.028
appendage development	GO:0048736	401	0.027
cellular component assembly involved in morphogenesis	GO:0010927	151	0.027
response to external biotic stimulus	GO:0043207	293	0.027
cellular catabolic process	GO:0044248	372	0.027
eye photoreceptor cell differentiation	GO:0001754	145	0.026
positive regulation of signaling	GO:0023056	243	0.026
cellular protein modification process	GO:0006464	438	0.026
response to temperature stimulus	GO:0009266	106	0.026
carboxylic acid metabolic process	GO:0019752	92	0.026
establishment of localization in cell	GO:0051649	402	0.025
regulation of immune system process	GO:0002682	176	0.025
regulation of cellular amino acid metabolic process	GO:0006521	0	0.025
organic acid metabolic process	GO:0006082	103	0.025
imaginal disc derived appendage development	GO:0048737	399	0.025
phagocytosis	GO:0006909	215	0.025	Fly
response to other organism	GO:0051707	293	0.025
spindle organization	GO:0007051	253	0.025
immune system process	GO:0002376	347	0.024
endocytosis	GO:0006897	310	0.024	Fly
wing disc morphogenesis	GO:0007472	344	0.024
regulation of cellular amine metabolic process	GO:0033238	3	0.024
regulation of molecular function	GO:0065009	217	0.024
appendage morphogenesis	GO:0035107	397	0.023
protein complex biogenesis	GO:0070271	201	0.023
catabolic process	GO:0009056	409	0.023
gland development	GO:0048732	191	0.023
photoreceptor cell differentiation	GO:0046530	170	0.022
organic substance catabolic process	GO:1901575	308	0.022
positive regulation of biosynthetic process	GO:0009891	316	0.022
regulation of catalytic activity	GO:0050790	185	0.022
response to biotic stimulus	GO:0009607	294	0.021
regulation of cellular ketone metabolic process	GO:0010565	3	0.021
protein localization	GO:0008104	284	0.021
cell proliferation	GO:0008283	299	0.021
cytoplasmic transport	GO:0016482	130	0.021
single organism behavior	GO:0044708	391	0.021
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.021
male gamete generation	GO:0048232	201	0.020
cell death	GO:0008219	279	0.020
imaginal disc derived wing morphogenesis	GO:0007476	337	0.020
cellularization	GO:0007349	90	0.020
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.019
modification dependent protein catabolic process	GO:0019941	78	0.019
neurological system process	GO:0050877	358	0.019	Fly
cellular protein catabolic process	GO:0044257	83	0.019
salivary gland morphogenesis	GO:0007435	145	0.019
autophagic cell death	GO:0048102	83	0.019
regulation of immune response	GO:0050776	118	0.019
proteasomal protein catabolic process	GO:0010498	59	0.018
mitotic spindle organization	GO:0007052	220	0.018
single organism intracellular transport	GO:1902582	207	0.018
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.018
epithelial cell development	GO:0002064	274	0.018
immune response	GO:0006955	246	0.018
tissue morphogenesis	GO:0048729	297	0.017
protein modification process	GO:0036211	438	0.017
intracellular transport	GO:0046907	228	0.017
small molecule metabolic process	GO:0044281	305	0.017
cellular macromolecule localization	GO:0070727	220	0.017
mitotic nuclear division	GO:0007067	213	0.017
gene silencing	GO:0016458	138	0.017
eye development	GO:0001654	323	0.016
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.016
salivary gland cell autophagic cell death	GO:0035071	83	0.016
programmed cell death	GO:0012501	257	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.016
morphogenesis of an epithelium	GO:0002009	276	0.016
positive regulation of cell communication	GO:0010647	250	0.016
negative regulation of cell communication	GO:0010648	223	0.016
rna processing	GO:0006396	147	0.016
negative regulation of gene expression epigenetic	GO:0045814	77	0.016
intracellular protein transport	GO:0006886	104	0.016
centrosome duplication	GO:0051298	121	0.015
regulation of gene expression epigenetic	GO:0040029	128	0.015
cellular amine metabolic process	GO:0044106	12	0.015
organic substance transport	GO:0071702	257	0.015
protein catabolic process	GO:0030163	101	0.015
developmental programmed cell death	GO:0010623	138	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
positive regulation of signal transduction	GO:0009967	223	0.015
cell projection assembly	GO:0030031	94	0.015
spindle assembly	GO:0051225	80	0.015
salivary gland histolysis	GO:0035070	88	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.015
compound eye development	GO:0048749	307	0.015
regulation of localization	GO:0032879	275	0.015
histolysis	GO:0007559	102	0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.014
negative regulation of rna metabolic process	GO:0051253	251	0.014
negative regulation of signal transduction	GO:0009968	206	0.014
protein transport	GO:0015031	155	0.014
defense response to other organism	GO:0098542	225	0.014
negative regulation of gene expression	GO:0010629	387	0.014
cellular response to chemical stimulus	GO:0070887	199	0.014
negative regulation of response to stimulus	GO:0048585	258	0.014
negative regulation of rna biosynthetic process	GO:1902679	240	0.014
nicotinamide nucleotide metabolic process	GO:0046496	2	0.014
macromolecule catabolic process	GO:0009057	161	0.014
protein modification by small protein conjugation or removal	GO:0070647	106	0.014
cognition	GO:0050890	141	0.014
proteolysis	GO:0006508	192	0.014
organelle localization	GO:0051640	148	0.014
positive regulation of cellular biosynthetic process	GO:0031328	316	0.014
cellular protein localization	GO:0034613	160	0.014
single organism biosynthetic process	GO:0044711	206	0.013
nuclear division	GO:0000280	332	0.013
cytokinesis	GO:0000910	90	0.013
regulation of anatomical structure morphogenesis	GO:0022603	242	0.013
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.013
hematopoietic progenitor cell differentiation	GO:0002244	1	0.013
triglyceride catabolic process	GO:0019433	3	0.013
single organism cellular localization	GO:1902580	180	0.013
embryonic development via the syncytial blastoderm	GO:0001700	148	0.013
regulation of endopeptidase activity	GO:0052548	36	0.013
cellular macromolecule catabolic process	GO:0044265	136	0.013
actin filament based process	GO:0030029	220	0.013
protein modification by small protein conjugation	GO:0032446	79	0.013
establishment of protein localization	GO:0045184	163	0.013
regulation of multi organism process	GO:0043900	131	0.013
carbohydrate derivative metabolic process	GO:1901135	217	0.013
positive regulation of cellular protein metabolic process	GO:0032270	118	0.012
negative regulation of cellular protein metabolic process	GO:0032269	85	0.012
ubiquitin dependent protein catabolic process	GO:0006511	78	0.012
regulation of proteolysis	GO:0030162	87	0.012
regulation of nervous system development	GO:0051960	248	0.012
tissue death	GO:0016271	102	0.012
salivary gland development	GO:0007431	162	0.012
intracellular signal transduction	GO:0035556	300	0.012
developmental growth	GO:0048589	280	0.012	Fly
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.012
epithelial cell differentiation	GO:0030855	322	0.012
sterol homeostasis	GO:0055092	4	0.012
phosphorylation	GO:0016310	294	0.012
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.012
negative regulation of biosynthetic process	GO:0009890	277	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
adult behavior	GO:0030534	137	0.012
glycosyl compound metabolic process	GO:1901657	127	0.011
posttranscriptional regulation of gene expression	GO:0010608	145	0.011
single organism catabolic process	GO:0044712	228	0.011
sensory organ morphogenesis	GO:0090596	260	0.011
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.011
chromatin silencing	GO:0006342	76	0.011
actin cytoskeleton organization	GO:0030036	206	0.011
negative regulation of defense response	GO:0031348	35	0.011
spindle assembly involved in mitosis	GO:0090307	50	0.011
regulation of gene silencing	GO:0060968	63	0.011
adult locomotory behavior	GO:0008344	76	0.011
regulation of protein localization	GO:0032880	76	0.011
wnt signaling pathway	GO:0016055	98	0.011
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.011
regulation of defense response	GO:0031347	102	0.011
cilium organization	GO:0044782	41	0.011
positive regulation of protein metabolic process	GO:0051247	128	0.011
central nervous system development	GO:0007417	201	0.011
regulation of response to stress	GO:0080134	200	0.011	Fly
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
locomotory behavior	GO:0007626	176	0.010
homeostatic process	GO:0042592	199	0.010
mitochondrion organization	GO:0007005	65	0.010
negative regulation of signaling	GO:0023057	219	0.010
alditol phosphate metabolic process	GO:0052646	2	0.010
cytoskeleton dependent cytokinesis	GO:0061640	81	0.010
anatomical structure homeostasis	GO:0060249	97	0.010
sperm individualization	GO:0007291	48	0.010
lipid metabolic process	GO:0006629	121	0.010
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.010
defense response	GO:0006952	300	0.010
columnar cuboidal epithelial cell development	GO:0002066	249	0.010
nucleotide metabolic process	GO:0009117	161	0.010

Ntl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.027
	nervous system disease	DOID:863	0	0.011

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