Drosophila melanogaster

22 known processes

Atg4 (Dmel_CG4428)

Autophagy-specific gene 4

(Aliases: Dmel\CG4428,atg4,CG4428)

Atg4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval midgut histolysisGO:0035069220.942
regulation of autophagyGO:0010506620.827
autophagyGO:00069141080.782
autophagic vacuole assemblyGO:000004520.764
Human Yeast
larval midgut cell programmed cell deathGO:0035096190.635
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.420
cellular response to starvationGO:0009267610.398
Human Yeast
regulation of nurse cell apoptotic processGO:004547790.305
macroautophagyGO:0016236420.292
Human Yeast
positive regulation of autophagyGO:0010508210.288
cellular catabolic processGO:00442483720.234
histolysisGO:00075591020.221
Fly
catabolic processGO:00090564090.206
regulation of tor signalingGO:0032006210.192
regulation of cellular catabolic processGO:00313291570.191
cellular response to extracellular stimulusGO:0031668640.160
Human Yeast
regulation of catabolic processGO:00098941700.150
cell deathGO:00082192790.149
Fly
response to starvationGO:0042594970.147
Human Yeast
positive regulation of response to stimulusGO:00485843230.143
response to oxygen containing compoundGO:19017002000.140
response to extracellular stimulusGO:00099911160.135
Human Yeast
tissue deathGO:00162711020.127
Fly
inositol lipid mediated signalingGO:004801740.123
phosphatidylinositol mediated signalingGO:004801540.118
intracellular signal transductionGO:00355563000.103
organelle assemblyGO:00709251980.102
Human Yeast
regulation of intracellular signal transductionGO:19025312360.101
cellular response to external stimulusGO:0071496660.098
Human Yeast
positive regulation of signalingGO:00230562430.097
vesicle mediated transportGO:00161923810.094
cellular response to nutrient levelsGO:0031669620.087
Human Yeast
protein localizationGO:00081042840.087
Yeast
response to nutrient levelsGO:00316671140.086
Human Yeast
positive regulation of catabolic processGO:00098961050.083
establishment of localization in cellGO:00516494020.083
Yeast
cellular protein modification processGO:00064644380.075
Yeast
lipid modificationGO:0030258240.073
tor signalingGO:0031929320.071
single organism catabolic processGO:00447122280.067
Human Yeast
protein modification processGO:00362114380.065
Yeast
developmental programmed cell deathGO:00106231380.063
Fly
deathGO:00162652840.060
Fly
negative regulation of signalingGO:00230572190.058
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.057
agingGO:00075681430.056
intracellular transportGO:00469072280.055
Yeast
response to other organismGO:00517072930.054
response to organonitrogen compoundGO:0010243750.054
response to organic substanceGO:00100332840.050
cellular response to chemical stimulusGO:00708871990.050
lateral inhibitionGO:00463312060.049
regulation of protein metabolic processGO:00512462560.048
negative regulation of signal transductionGO:00099682060.047
protein secretionGO:0009306450.046
response to alcoholGO:0097305950.045
cellular response to oxidative stressGO:0034599280.045
single organism biosynthetic processGO:00447112060.042
small molecule metabolic processGO:00442813050.042
developmental growthGO:00485892800.042
carboxylic acid metabolic processGO:0019752920.042
response to nitrogen compoundGO:1901698900.042
programmed cell deathGO:00125012570.041
Fly
endomembrane system organizationGO:00102561190.041
positive regulation of signal transductionGO:00099672230.039
phagocytosisGO:00069092150.039
establishment of protein localizationGO:00451841630.039
Yeast
cellular protein localizationGO:00346131600.038
Yeast
positive regulation of cell communicationGO:00106472500.037
negative regulation of intracellular signal transductionGO:1902532570.037
organic substance transportGO:00717022570.037
Yeast
negative regulation of macromolecule biosynthetic processGO:00105582700.035
nurse cell apoptotic processGO:0045476170.035
growthGO:00400073590.034
phosphorylationGO:00163102940.033
anion homeostasisGO:005508130.032
phosphatidylinositol 3 kinase signalingGO:001406540.032
regulation of localizationGO:00328792750.032
protein transportGO:00150311550.032
Yeast
negative regulation of response to stimulusGO:00485852580.032
regulation of phosphorus metabolic processGO:00511742100.032
positive regulation of phosphorus metabolic processGO:00105621390.031
endocytosisGO:00068973100.031
organic substance catabolic processGO:19015753080.030
regulation of response to external stimulusGO:00321011150.030
immune system processGO:00023763470.030
regulation of multi organism processGO:00439001310.029
cytoplasmic transportGO:00164821300.029
Yeast
apoptotic processGO:00069151590.029
response to organic cyclic compoundGO:0014070890.029
gtp metabolic processGO:0046039720.029
regulation of protein transportGO:0051223570.028
multicellular organismal agingGO:00102591400.028
imaginal disc derived wing morphogenesisGO:00074763370.028
regulation of cellular protein metabolic processGO:00322682430.028
response to endogenous stimulusGO:00097191190.028
defense responseGO:00069523000.028
negative regulation of cell communicationGO:00106482230.028
organonitrogen compound metabolic processGO:19015643180.027
regulation of response to stressGO:00801342000.027
appendage developmentGO:00487364010.027
response to biotic stimulusGO:00096072940.027
lipid metabolic processGO:00066291210.026
golgi vesicle transportGO:0048193270.026
positive regulation of transcription dna templatedGO:00458932660.026
positive regulation of multicellular organismal processGO:00512401430.025
regulation of phosphate metabolic processGO:00192202100.025
organophosphate metabolic processGO:00196371950.025
cellular response to endogenous stimulusGO:0071495800.025
nitrogen compound transportGO:0071705850.025
oxoacid metabolic processGO:00434361030.024
determination of adult lifespanGO:00083401370.024
positive regulation of intracellular signal transductionGO:19025331160.024
regulation of secretion by cellGO:1903530390.024
stress activated mapk cascadeGO:0051403520.023
organelle fissionGO:00482853400.023
embryonic morphogenesisGO:00485982060.023
interspecies interaction between organismsGO:0044419160.022
guanosine containing compound catabolic processGO:1901069740.022
cell cell signaling involved in cell fate commitmentGO:00451682100.022
regulation of mapk cascadeGO:0043408920.022
maintenance of locationGO:0051235730.022
positive regulation of gene expressionGO:00106282900.022
single organism behaviorGO:00447083910.022
regulation of protein secretionGO:0050708130.022
organic acid metabolic processGO:00060821030.022
response to organophosphorusGO:004668320.022
single organism membrane fusionGO:0044801420.022
regulation of cellular localizationGO:00603411360.021
single organism cellular localizationGO:19025801800.021
Yeast
apoptotic process involved in developmentGO:1902742200.021
signal transduction by phosphorylationGO:00230141070.020
regulation of response to biotic stimulusGO:0002831630.020
actin cytoskeleton organizationGO:00300362060.020
regulation of cell differentiationGO:00455953020.020
regulation of anatomical structure sizeGO:00900661630.020
regulation of establishment of protein localizationGO:0070201610.020
response to external biotic stimulusGO:00432072930.019
regulation of developmental growthGO:00486381740.019
regulation of transportGO:00510491810.019
membrane fusionGO:0061025420.019
positive regulation of cell migrationGO:003033520.019
mapk cascadeGO:00001651070.019
cell type specific apoptotic processGO:0097285380.019
defense response to other organismGO:00985422250.019
ribonucleoside metabolic processGO:00091191270.019
regulation of immune system processGO:00026821760.019
protein ubiquitinationGO:0016567700.019
cellular macromolecule localizationGO:00707272200.018
Yeast
positive regulation of tor signalingGO:0032008130.018
negative regulation of cellular metabolic processGO:00313243820.018
positive regulation of mapk cascadeGO:0043410630.018
imaginal disc derived appendage morphogenesisGO:00351143950.018
guanosine containing compound metabolic processGO:1901068740.018
protein complex biogenesisGO:00702712010.018
wing disc morphogenesisGO:00074723440.018
aggressive behaviorGO:0002118630.018
negative regulation of insulin receptor signaling pathwayGO:0046627110.017
positive regulation of phosphate metabolic processGO:00459371390.017
regulation of protein localizationGO:0032880760.017
protein catabolic processGO:00301631010.017
protein modification by small protein conjugationGO:0032446790.017
single organism intracellular transportGO:19025822070.017
Yeast
post embryonic appendage morphogenesisGO:00351203850.017
macromolecular complex assemblyGO:00650032560.017
cellular lipid metabolic processGO:0044255830.017
enzyme linked receptor protein signaling pathwayGO:00071671790.016
nucleoside phosphate metabolic processGO:00067531620.016
organic cyclic compound catabolic processGO:19013611680.016
positive regulation of developmental processGO:00510941430.016
cellular response to nitrogen compoundGO:1901699510.016
positive regulation of nucleobase containing compound metabolic processGO:00459353320.016
organic hydroxy compound metabolic processGO:1901615830.016
positive regulation of programmed cell deathGO:0043068620.016
cell proliferationGO:00082832990.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
regulation of cellular amine metabolic processGO:003323830.016
secretion by cellGO:00329401010.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.016
cellular response to oxygen containing compoundGO:1901701790.016
regulation of catalytic activityGO:00507901850.015
response to hexoseGO:000974630.015
macromolecule catabolic processGO:00090571610.015
protein modification by small protein conjugation or removalGO:00706471060.015
protein complex assemblyGO:00064612000.015
regulation of cellular component biogenesisGO:00440872010.015
positive regulation of phosphorylationGO:0042327870.015
appendage morphogenesisGO:00351073970.015
regulation of secretionGO:0051046440.015
inter male aggressive behaviorGO:0002121600.015
ras protein signal transductionGO:0007265880.014
body morphogenesisGO:001017120.014
response to ethanolGO:0045471590.014
vesicle localizationGO:0051648550.014
morphogenesis of an epitheliumGO:00020092760.014
phosphatidylinositol phosphorylationGO:0046854100.014
cellular response to hormone stimulusGO:0032870440.014
organelle localizationGO:00516401480.014
regulation of cell deathGO:00109411730.014
jnk cascadeGO:0007254500.014
nucleotide metabolic processGO:00091171610.014
positive regulation of nurse cell apoptotic processGO:004585050.014
regulation of nervous system developmentGO:00519602480.014
regulation of molecular functionGO:00650092170.014
sensory perception of smellGO:0007608800.013
regulation of cellular amino acid metabolic processGO:000652100.013
carbohydrate metabolic processGO:0005975820.013
protein heterooligomerizationGO:005129140.013
regulation of purine nucleotide catabolic processGO:0033121480.013
organonitrogen compound catabolic processGO:19015651280.013
regulation of phosphorylationGO:00423251470.013
response to acid chemicalGO:0001101250.013
heterocycle catabolic processGO:00467001660.013
regulation of protein modification processGO:00313991120.013
gastrulation involving germ band extensionGO:0010004360.013
nucleocytoplasmic transportGO:0006913720.013
regulation of hydrolase activityGO:0051336970.013
positive regulation of cell differentiationGO:0045597640.013
cellular response to ethanolGO:007136140.013
regionalizationGO:00030024160.012
regulation of gtpase activityGO:0043087440.012
triglyceride biosynthetic processGO:001943220.012
positive regulation of macromolecule biosynthetic processGO:00105572830.012
secretionGO:00469031090.012
digestive tract developmentGO:00485651490.012
actin filament organizationGO:00070151260.012
purine ribonucleoside metabolic processGO:00461281270.012
membrane organizationGO:00610241120.012
Yeast
positive regulation of rna biosynthetic processGO:19026802660.012
regulation of growthGO:00400082330.012
stress activated protein kinase signaling cascadeGO:0031098550.012
glycerophospholipid metabolic processGO:0006650230.012
carbohydrate derivative catabolic processGO:19011361180.012
regulation of immune responseGO:00507761180.012
positive regulation of macromolecule metabolic processGO:00106044050.012
embryonic development via the syncytial blastodermGO:00017001480.012
organophosphate catabolic processGO:00464341120.011
regulation of stress activated protein kinase signaling cascadeGO:0070302420.011
negative regulation of gene expressionGO:00106293870.011
cellular iron ion homeostasisGO:000687930.011
chaeta developmentGO:0022416970.011
regulation of defense responseGO:00313471020.011
regulation of tube sizeGO:0035150460.011
embryo development ending in birth or egg hatchingGO:00097921520.011
regulation of cell proliferationGO:00421271630.011
response to insulinGO:0032868290.011
cellular metal ion homeostasisGO:0006875310.011
endosomal transportGO:0016197440.011
intracellular protein transportGO:00068861040.011
Yeast
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
positive regulation of cell motilityGO:200014730.011
dendrite morphogenesisGO:00488131990.011
translationGO:0006412690.011
immune effector processGO:0002252980.011
nucleobase containing small molecule metabolic processGO:00550861740.011
central nervous system developmentGO:00074172010.011
cellular ketone metabolic processGO:0042180240.011
positive regulation of biosynthetic processGO:00098913160.011
cellular transition metal ion homeostasisGO:004691690.011
cell divisionGO:00513012480.011
chemical homeostasisGO:0048878920.011
transcription from rna polymerase ii promoterGO:00063663680.011
rna localizationGO:00064031150.011
ribonucleotide metabolic processGO:00092591450.011
spindle assemblyGO:0051225800.011
epithelial cell differentiationGO:00308553220.011
imaginal disc derived appendage developmentGO:00487373990.011
oxidation reduction processGO:00551141230.011
cellular amine metabolic processGO:0044106120.011
regulation of stress activated mapk cascadeGO:0032872410.010
response to inorganic substanceGO:0010035440.010
proteolysis involved in cellular protein catabolic processGO:0051603830.010
pyridine nucleotide metabolic processGO:001936220.010
positive regulation of cell deathGO:0010942690.010
protein processingGO:0016485680.010
Yeast
carbohydrate derivative metabolic processGO:19011352170.010
response to glucoseGO:000974920.010
negative regulation of protein metabolic processGO:0051248850.010
kidney developmentGO:000182230.010
positive regulation of multi organism processGO:0043902400.010
regulation of cell cycleGO:00517262910.010
positive regulation of apoptotic processGO:0043065470.010
negative regulation of notch signaling pathwayGO:0045746410.010

Atg4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.268
disease of metabolismDOID:001466700.014
nervous system diseaseDOID:86300.013
central nervous system diseaseDOID:33100.012