Drosophila melanogaster

149 known processes

cbt (Dmel_CG4427)

cabut

(Aliases: Cabut,EP(2)2237,dTIEG,Cabot,CG4427,EP2237,Dmel\CG4427)

cbt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic morphogenesisGO:00485982060.883
dorsal closureGO:0007391790.878
morphogenesis of an epitheliumGO:00020092760.847
morphogenesis of embryonic epitheliumGO:0016331940.565
head involutionGO:0008258350.544
embryonic development via the syncytial blastodermGO:00017001480.518
tissue morphogenesisGO:00487292970.487
cellular response to chemical stimulusGO:00708871990.487
Rat
regulation of intracellular signal transductionGO:19025312360.411
appendage developmentGO:00487364010.361
Fly
enzyme linked receptor protein signaling pathwayGO:00071671790.302
organonitrogen compound metabolic processGO:19015643180.266
gland morphogenesisGO:00226121450.258
cell divisionGO:00513012480.227
oxoacid metabolic processGO:00434361030.222
response to light stimulusGO:00094161240.214
homeostatic processGO:00425921990.206
negative regulation of cell communicationGO:00106482230.201
intracellular signal transductionGO:00355563000.183
vesicle mediated transportGO:00161923810.170
Worm
regulation of phosphate metabolic processGO:00192202100.166
regulation of cellular response to stressGO:0080135890.161
chaeta developmentGO:0022416970.160
negative regulation of gene expressionGO:00106293870.159
organic acid metabolic processGO:00060821030.153
positive regulation of phosphate metabolic processGO:00459371390.152
post embryonic appendage morphogenesisGO:00351203850.149
Fly
negative regulation of signal transductionGO:00099682060.149
programmed cell deathGO:00125012570.148
imaginal disc derived wing morphogenesisGO:00074763370.147
endocytosisGO:00068973100.141
Worm
regulation of cell proliferationGO:00421271630.129
Human
glycosyl compound catabolic processGO:19016581120.127
imaginal disc derived appendage morphogenesisGO:00351143950.123
Fly
cell maturationGO:00484691440.122
establishment of localization in cellGO:00516494020.120
autophagyGO:00069141080.119
negative regulation of response to stimulusGO:00485852580.110
positive regulation of nitrogen compound metabolic processGO:00511733540.109
Worm Fly
embryo development ending in birth or egg hatchingGO:00097921520.108
wing disc morphogenesisGO:00074723440.106
salivary gland cell autophagic cell deathGO:0035071830.105
digestive tract developmentGO:00485651490.102
Fly
actin filament organizationGO:00070151260.102
carboxylic acid metabolic processGO:0019752920.100
appendage morphogenesisGO:00351073970.098
Fly
regulation of programmed cell deathGO:00430671520.095
Human Worm
regulation of cell deathGO:00109411730.095
Human Worm
single organism biosynthetic processGO:00447112060.085
cell deathGO:00082192790.083
actin cytoskeleton organizationGO:00300362060.083
response to organic substanceGO:00100332840.082
Rat
regulation of response to stressGO:00801342000.081
regulation of neuron projection developmentGO:0010975690.081
regulation of immune system processGO:00026821760.078
Mouse
deathGO:00162652840.077
regulation of cellular ketone metabolic processGO:001056530.077
cellular response to abiotic stimulusGO:0071214580.074
regulation of catabolic processGO:00098941700.074
cell fate determinationGO:0001709910.074
negative regulation of cell differentiationGO:00455961430.074
Mouse
regulation of cell cycleGO:00517262910.073
peptidyl amino acid modificationGO:00181931050.073
regulation of phosphorylationGO:00423251470.072
phosphorylationGO:00163102940.070
immune responseGO:00069552460.067
purine nucleoside triphosphate metabolic processGO:00091441190.065
exocrine system developmentGO:00352721620.065
imaginal disc derived appendage developmentGO:00487373990.065
Fly
cellular response to starvationGO:0009267610.063
Mouse
regulation of cellular localizationGO:00603411360.062
positive regulation of cell proliferationGO:0008284470.062
carbohydrate homeostasisGO:0033500120.057
polysaccharide biosynthetic processGO:000027170.057
cellular response to organic substanceGO:00713101320.056
Rat
negative regulation of rna metabolic processGO:00512532510.055
protein phosphorylationGO:00064681690.054
stress activated mapk cascadeGO:0051403520.053
protein localizationGO:00081042840.052
cellular response to molecule of bacterial originGO:007121930.052
regulation of cellular amino acid metabolic processGO:000652100.051
positive regulation of protein metabolic processGO:00512471280.051
regulation of secretion by cellGO:1903530390.049
histolysisGO:00075591020.049
gene silencingGO:00164581380.048
salivary gland developmentGO:00074311620.048
establishment of organelle localizationGO:00516561220.048
actin filament based processGO:00300292200.047
cell proliferationGO:00082832990.046
Human
negative regulation of smoothened signaling pathwayGO:0045879160.046
neuroblast proliferationGO:0007405740.046
regulation of multicellular organismal developmentGO:20000264140.045
Mouse
positive regulation of transcription dna templatedGO:00458932660.045
Worm Fly
mesoderm developmentGO:0007498780.045
compound eye developmentGO:00487493070.044
response to radiationGO:00093141550.044
regulation of epithelial cell differentiationGO:003085640.044
stress activated protein kinase signaling cascadeGO:0031098550.044
positive regulation of cellular amine metabolic processGO:003324000.044
defense response to other organismGO:00985422250.044
Fly
salivary gland histolysisGO:0035070880.044
digestive tract morphogenesisGO:00485461270.042
Fly
salivary gland morphogenesisGO:00074351450.041
cardiac cell fate determinationGO:006091330.041
small molecule metabolic processGO:00442813050.041
positive regulation of rna biosynthetic processGO:19026802660.040
Worm Fly
synapse assemblyGO:00074161430.040
positive regulation of developmental processGO:00510941430.039
Mouse
rhythmic processGO:00485111060.039
Mouse Rat
positive regulation of phosphorus metabolic processGO:00105621390.039
compound eye morphogenesisGO:00017452490.039
cellular amino acid metabolic processGO:0006520610.039
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.038
tissue deathGO:00162711020.038
cellular ketone metabolic processGO:0042180240.037
response to external biotic stimulusGO:00432072930.037
Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.036
response to bacteriumGO:00096171980.036
regulation of mitotic cell cycleGO:00073461900.035
response to oxidative stressGO:0006979860.035
regulation of anatomical structure morphogenesisGO:00226032420.034
mapk cascadeGO:00001651070.034
negative regulation of wnt signaling pathwayGO:0030178280.034
regulation of molecular functionGO:00650092170.033
immune response regulating signaling pathwayGO:000276420.033
regulation of cell developmentGO:00602842150.033
female germ line stem cell asymmetric divisionGO:0048132140.032
establishment or maintenance of cell polarityGO:00071631670.032
glucose homeostasisGO:004259360.032
negative regulation of insulin secretionGO:004667610.032
body morphogenesisGO:001017120.032
Worm
organelle assemblyGO:00709251980.032
regulation of response to dna damage stimulusGO:2001020230.032
negative regulation of signalingGO:00230572190.032
carboxylic acid transportGO:0046942180.031
negative regulation of developmental processGO:00510932010.031
Mouse
organ formationGO:0048645390.031
cortical cytoskeleton organizationGO:0030865290.030
purine nucleoside catabolic processGO:00061521120.030
regulation of response to external stimulusGO:00321011150.030
ribonucleotide metabolic processGO:00092591450.030
negative regulation of cellular metabolic processGO:00313243820.030
regulation of cellular component biogenesisGO:00440872010.030
positive regulation of signalingGO:00230562430.030
regulation of gtpase activityGO:0043087440.030
regulation of cellular catabolic processGO:00313291570.030
purine nucleoside metabolic processGO:00422781270.029
neurological system processGO:00508773580.029
peptidyl threonine phosphorylationGO:001810720.029
positive regulation of catabolic processGO:00098961050.029
catabolic processGO:00090564090.029
regulation of cellular amine metabolic processGO:003323830.028
regionalizationGO:00030024160.028
nitrogen compound transportGO:0071705850.028
single organism behaviorGO:00447083910.028
protein modification processGO:00362114380.027
regulation of actin filament based processGO:0032970420.027
posttranscriptional regulation of gene expressionGO:00106081450.027
cellular protein localizationGO:00346131600.027
regulation of synapse assemblyGO:0051963940.027
synaptic growth at neuromuscular junctionGO:00511241190.026
gastrulationGO:0007369700.026
Fly
signal transduction by phosphorylationGO:00230141070.026
ras protein signal transductionGO:0007265880.026
regulation of notch signaling pathwayGO:00085931000.025
negative regulation of transcription dna templatedGO:00458922370.025
eye morphogenesisGO:00485922600.025
response to oxygen containing compoundGO:19017002000.025
Rat
autophagic cell deathGO:0048102830.025
larval developmentGO:00021641040.025
Worm
regulation of protein metabolic processGO:00512462560.025
regulation of epithelial cell proliferationGO:005067840.025
positive regulation of cellular biosynthetic processGO:00313283160.024
Worm Fly
response to endogenous stimulusGO:00097191190.024
Rat
cellular component assembly involved in morphogenesisGO:00109271510.024
defense responseGO:00069523000.024
Fly
jnk cascadeGO:0007254500.024
cytokinesisGO:0000910900.024
regulation of stem cell proliferationGO:0072091400.024
transcription from rna polymerase ii promoterGO:00063663680.024
response to other organismGO:00517072930.023
Fly
enteroendocrine cell differentiationGO:003588310.023
synapse organizationGO:00508081960.023
regulation of stress activated protein kinase signaling cascadeGO:0070302420.023
cellular catabolic processGO:00442483720.023
regulation of nervous system developmentGO:00519602480.023
positive regulation of macromolecule metabolic processGO:00106044050.023
Worm Fly
eye developmentGO:00016543230.023
regulation of cell differentiationGO:00455953020.022
Mouse
germline stem cell asymmetric divisionGO:0098728150.022
germ band shorteningGO:0007390190.021
dendrite developmentGO:00163582040.021
formation of primary germ layerGO:0001704240.021
regulation of organ morphogenesisGO:2000027780.021
cellular response to oxygen containing compoundGO:1901701790.021
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
Worm Fly
response to glucoseGO:000974920.021
single organism intracellular transportGO:19025822070.021
establishment of protein localizationGO:00451841630.021
small gtpase mediated signal transductionGO:0007264880.021
negative regulation of programmed cell deathGO:0043069720.021
negative regulation of hormone biosynthetic processGO:003235310.021
columnar cuboidal epithelial cell developmentGO:00020662490.020
dendrite morphogenesisGO:00488131990.020
response to woundingGO:0009611940.020
positive regulation of cell communicationGO:00106472500.020
positive regulation of developmental growthGO:0048639620.020
cellular protein modification processGO:00064644380.020
regulation of ras protein signal transductionGO:0046578930.020
response to starvationGO:0042594970.020
Mouse
regulation of jnk cascadeGO:0046328400.019
neural precursor cell proliferationGO:0061351750.019
regulation of phosphorus metabolic processGO:00511742100.019
negative regulation of kinase activityGO:0033673160.019
positive regulation of cell differentiationGO:0045597640.019
Mouse
heterocycle catabolic processGO:00467001660.019
defense response to bacteriumGO:00427421780.019
digestive system developmentGO:00551231490.019
Fly
spindle organizationGO:00070512530.018
positive regulation of phosphorylationGO:0042327870.018
positive regulation of cell motilityGO:200014730.018
developmental maturationGO:00217001720.018
ribonucleoside metabolic processGO:00091191270.018
anion transportGO:0006820410.018
maintenance of locationGO:0051235730.018
maintenance of protein location in cellGO:0032507260.018
positive regulation of response to stimulusGO:00485843230.018
rna processingGO:00063961470.018
lipopolysaccharide mediated signaling pathwayGO:003166310.017
polysaccharide metabolic processGO:0005976110.017
centrosome organizationGO:00512971630.017
mrna processingGO:00063971040.017
positive regulation of protein modification processGO:0031401580.017
regulation of cellular protein metabolic processGO:00322682430.017
negative regulation of autophagyGO:0010507160.017
multi organism behaviorGO:00517051750.017
positive regulation of apoptotic processGO:0043065470.017
Human Worm
regulation of localizationGO:00328792750.017
maintenance of location in cellGO:0051651280.017
positive regulation of cell migrationGO:003033520.017
germ line stem cell divisionGO:0042078250.017
organelle localizationGO:00516401480.017
microtubule organizing center organizationGO:00310231680.017
secretion by cellGO:00329401010.016
single organismal cell cell adhesionGO:0016337450.016
regulation of protein modification processGO:00313991120.016
heart processGO:0003015370.016
response to abiotic stimulusGO:00096283410.016
positive regulation of gene expressionGO:00106282900.016
Worm Fly
formation of anatomical boundaryGO:0048859370.016
positive regulation of cellular component biogenesisGO:0044089800.016
chorion containing eggshell formationGO:00073041050.016
regulation of ion transportGO:0043269390.016
single organism cellular localizationGO:19025801800.016
regulation of gene expression epigeneticGO:00400291280.016
negative regulation of multicellular organismal processGO:00512411420.015
stem cell proliferationGO:0072089880.015
regulation of cytoskeleton organizationGO:0051493890.015
localization of cellGO:00516742570.015
immune system processGO:00023763470.015
Mouse
regulation of immune responseGO:00507761180.015
intracellular transportGO:00469072280.015
positive regulation of signal transductionGO:00099672230.015
negative regulation of phosphorylationGO:0042326350.015
cytoskeleton dependent intracellular transportGO:0030705440.015
gliogenesisGO:0042063800.015
phagocytosisGO:00069092150.015
response to lipopolysaccharideGO:003249640.015
growthGO:00400073590.015
positive regulation of multicellular organism growthGO:0040018210.015
positive regulation of growthGO:0045927750.015
anatomical structure homeostasisGO:0060249970.015
regulation of autophagyGO:0010506620.015
nephron developmentGO:007200630.014
positive regulation of molecular functionGO:00440931360.014
epidermal growth factor receptor signaling pathwayGO:0007173580.014
purine ribonucleoside triphosphate metabolic processGO:00092051190.014
negative regulation of nervous system developmentGO:0051961920.014
regulation of response to woundingGO:1903034190.014
regulation of wnt signaling pathwayGO:0030111680.014
limb developmentGO:006017310.014
regulation of nucleoside metabolic processGO:0009118500.014
regulation of mapk cascadeGO:0043408920.014
erbb signaling pathwayGO:0038127580.014
positive regulation of catalytic activityGO:00430851180.014
cellular response to lipopolysaccharideGO:007122230.014
regulation of bmp signaling pathwayGO:0030510230.014
regulation of small gtpase mediated signal transductionGO:0051056930.014
positive regulation of cellular protein metabolic processGO:00322701180.014
gland developmentGO:00487321910.013
multicellular organismal agingGO:00102591400.013
Worm
detection of stimulusGO:00516061560.013
dna biosynthetic processGO:0071897240.013
mrna splicing via spliceosomeGO:0000398730.013
ion transportGO:00068111450.013
negative regulation of apoptotic processGO:0043066630.013
biological adhesionGO:00226101380.013
regulation of embryonic developmentGO:0045995680.013
regulation of synapse organizationGO:00508071100.013
ameboidal type cell migrationGO:00016671510.013
regulation of hemocyte proliferationGO:0035206370.013
positive regulation of secretion by cellGO:1903532200.013
protein polymerizationGO:0051258420.013
amine metabolic processGO:0009308120.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
negative regulation of biosynthetic processGO:00098902770.013
negative regulation of small gtpase mediated signal transductionGO:0051058130.013
endodermal cell differentiationGO:003598730.013
actin filament polymerizationGO:0030041270.013
cellular response to ethanolGO:007136140.013
sensory organ morphogenesisGO:00905962600.013
microtubule based movementGO:0007018510.012
positive regulation of lipid biosynthetic processGO:004688930.012
intracellular protein transportGO:00068861040.012
regulation of protein phosphorylationGO:0001932640.012
positive regulation of intracellular signal transductionGO:19025331160.012
dephosphorylationGO:0016311510.012
carbohydrate derivative metabolic processGO:19011352170.012
ribose phosphate metabolic processGO:00196931450.012
cellular response to radiationGO:0071478520.012
regulation of nucleotide catabolic processGO:0030811480.012
tube morphogenesisGO:00352391910.012
Fly
cell cycle phase transitionGO:00447701400.012
Human
carbohydrate biosynthetic processGO:0016051170.012
response to monosaccharideGO:003428440.012
developmental programmed cell deathGO:00106231380.012
actin filament bundle organizationGO:0061572280.012
chaeta morphogenesisGO:0008407420.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.011
regulation of synapse structure and activityGO:00508031280.011
feeding behaviorGO:0007631500.011
dorsal ventral pattern formationGO:00099531330.011
actin polymerization or depolymerizationGO:0008154310.011
negative regulation of intracellular signal transductionGO:1902532570.011
regulation of response to biotic stimulusGO:0002831630.011
embryonic hemopoiesisGO:0035162260.011
regulation of neuroblast proliferationGO:1902692340.011
positive regulation of cellular catabolic processGO:0031331950.011
organic substance transportGO:00717022570.011
smoothened signaling pathwayGO:0007224490.011
guanosine containing compound metabolic processGO:1901068740.011
purine containing compound metabolic processGO:00725211550.011
notch signaling pathwayGO:00072191200.011
response to transforming growth factor betaGO:0071559180.011
developmental growthGO:00485892800.011
actin cytoskeleton reorganizationGO:0031532220.011
agingGO:00075681430.011
Worm
cellular macromolecule localizationGO:00707272200.011
regulation of transferase activityGO:0051338580.011
purine nucleotide catabolic processGO:00061951090.011
nucleoside triphosphate catabolic processGO:00091431080.011
translationGO:0006412690.010
purine ribonucleoside metabolic processGO:00461281270.010
regulation of polysaccharide biosynthetic processGO:003288510.010
chemical homeostasisGO:0048878920.010
gene silencing by rnaGO:0031047570.010
columnar cuboidal epithelial cell differentiationGO:00020652560.010
smad protein import into nucleusGO:0007184110.010
divalent inorganic cation homeostasisGO:0072507290.010
nucleoside phosphate catabolic processGO:19012921100.010
immune system developmentGO:0002520570.010
Mouse
nucleoside phosphate metabolic processGO:00067531620.010

cbt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.027
nervous system diseaseDOID:86300.027
eye and adnexa diseaseDOID:149200.027
eye diseaseDOID:561400.027
disease of anatomical entityDOID:700.027
acquired metabolic diseaseDOID:006015800.016
disease of metabolismDOID:001466700.016
carbohydrate metabolism diseaseDOID:005001300.016
glucose metabolism diseaseDOID:419400.014
diabetes mellitusDOID:935100.014
inherited metabolic disorderDOID:65500.012
cardiovascular system diseaseDOID:128700.010