Drosophila melanogaster

38 known processes

PGRP-SC1b (Dmel_CG8577)

CG8577 gene product from transcript CG8577-RA

(Aliases: PGRP-SC,Dmel\CG8577,CT8705,CG8577,PGRP SC,PGRP-SC1B,SC1B,PGRP-SC1)

PGRP-SC1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glycosaminoglycan catabolic processGO:000602730.359
lipopolysaccharide mediated signaling pathwayGO:003166310.333
Fly
pigment metabolic processGO:0042440840.300
Fly
secondary metabolic processGO:0019748750.280
Fly
melanin metabolic processGO:0006582470.278
Fly
peptide metabolic processGO:0006518800.276
Fly
defense response to virusGO:0051607230.235
Fly
immune response regulating signaling pathwayGO:000276420.232
Human Fly
immune response activating signal transductionGO:000275720.225
Human Fly
pattern recognition receptor signaling pathwayGO:000222120.214
Human Fly
regulation of defense response to bacteriumGO:1900424300.199
Fly
response to external biotic stimulusGO:00432072930.198
Human Fly
defense response to bacteriumGO:00427421780.196
Human Fly
circadian behaviorGO:0048512760.195
Rat
circadian sleep wake cycle processGO:0022410240.177
Rat
response to lipopolysaccharideGO:003249640.170
Fly
rhythmic behaviorGO:0007622760.167
Rat
peptidoglycan catabolic processGO:000925330.164
phenol containing compound metabolic processGO:0018958570.160
Fly
regulation of defense responseGO:00313471020.151
defense responseGO:00069523000.148
antimicrobial peptide productionGO:0002775460.147
Fly
positive regulation of multi organism processGO:0043902400.140
Fly
cellular response to lipopolysaccharideGO:007122230.138
Fly
response to bacteriumGO:00096171980.138
Human Fly
defense response to other organismGO:00985422250.133
Human Fly
single organism behaviorGO:00447083910.130
Rat
innate immune responseGO:00450871440.129
rhythmic processGO:00485111060.126
Rat
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000696530.123
Fly
determination of adult lifespanGO:00083401370.123
Fly
immune system processGO:00023763470.123
peptidoglycan recognition protein signaling pathwayGO:0061057160.120
Fly
negative regulation of immune system processGO:0002683500.118
positive regulation of response to external stimulusGO:0032103440.118
Fly
antimicrobial humoral responseGO:0019730990.117
Fly
regulation of humoral immune responseGO:0002920510.116
Fly
positive regulation of production of molecular mediator of immune responseGO:0002702280.116
Fly
defense response to gram positive bacteriumGO:0050830410.115
Human Fly
immune effector processGO:0002252980.114
Mouse Fly
peptidoglycan metabolic processGO:000027030.112
response to organic substanceGO:00100332840.111
Fly
intracellular signal transductionGO:00355563000.111
Fly
response to other organismGO:00517072930.111
Human Fly
negative regulation of cell communicationGO:00106482230.110
Fly
regulation of antibacterial peptide productionGO:0002786220.108
Fly
negative regulation of defense responseGO:0031348350.107
positive regulation of defense response to bacteriumGO:1900426230.107
Fly
negative regulation of cellular metabolic processGO:00313243820.107
Fly
detection of stimulusGO:00516061560.106
Human
response to biotic stimulusGO:00096072940.105
Human Fly
sleepGO:0030431490.105
Rat
positive regulation of response to biotic stimulusGO:0002833310.104
Fly
regulation of immune system processGO:00026821760.102
humoral immune responseGO:00069591170.101
Fly
antibacterial peptide biosynthetic processGO:0002780220.098
Fly
cellular amide metabolic processGO:0043603800.096
Fly
peptide biosynthetic processGO:0043043420.096
Fly
regulation of circadian rhythmGO:0042752490.095
Rat
positive regulation of response to stimulusGO:00485843230.095
Human Fly
regulation of multi organism processGO:00439001310.095
Fly
positive regulation of immune effector processGO:0002699280.095
Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.093
Fly
catabolic processGO:00090564090.092
production of molecular mediator of immune responseGO:0002440460.091
Fly
regulation of immune responseGO:00507761180.090
organonitrogen compound biosynthetic processGO:19015661170.089
Fly
immune responseGO:00069552460.088
positive regulation of defense responseGO:0031349590.088
Human Fly
carbohydrate derivative metabolic processGO:19011352170.085
regulation of response to external stimulusGO:00321011150.084
Fly
regulation of response to stressGO:00801342000.084
regulation of intracellular signal transductionGO:19025312360.081
Fly
glycosaminoglycan metabolic processGO:0030203110.081
phosphorylationGO:00163102940.080
Fly
organonitrogen compound catabolic processGO:19015651280.079
response to virusGO:0009615280.078
Fly
response to nitrogen compoundGO:1901698900.075
Fly
negative regulation of response to stimulusGO:00485852580.074
regulation of innate immune responseGO:0045088710.073
amide biosynthetic processGO:0043604420.073
Fly
negative regulation of immune responseGO:0050777390.072
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.072
Fly
antibacterial peptide productionGO:0002778220.071
Fly
organonitrogen compound metabolic processGO:19015643180.070
cellular response to molecule of bacterial originGO:007121930.070
Fly
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.070
Fly
organic substance catabolic processGO:19015753080.069
biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002812140.069
Fly
regulation of antimicrobial peptide biosynthetic processGO:0002805380.068
Fly
positive regulation of humoral immune responseGO:0002922280.067
Fly
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0006964120.067
Fly
defense response to gram negative bacteriumGO:0050829940.065
Fly
regulation of antimicrobial humoral responseGO:0002759500.065
Fly
negative regulation of signalingGO:00230572190.063
Fly
response to oxygen containing compoundGO:19017002000.062
Fly
negative regulation of peptidoglycan recognition protein signaling pathwayGO:006106030.062
Fly
response to endogenous stimulusGO:00097191190.060
Fly
regulation of secondary metabolic processGO:004345570.059
Fly
signal transduction by phosphorylationGO:00230141070.059
Fly
multicellular organismal agingGO:00102591400.059
Fly
positive regulation of biosynthetic processGO:00098913160.059
Fly
regulation of phosphate metabolic processGO:00192202100.058
Fly
response to molecule of bacterial originGO:000223770.058
Fly
regulation of multicellular organismal developmentGO:20000264140.057
Mouse
regulation of circadian sleep wake cycle sleepGO:0045187210.056
Rat
growthGO:00400073590.056
Mouse
circadian sleep wake cycle sleepGO:0050802230.055
Rat
regulation of stress activated mapk cascadeGO:0032872410.052
Fly
stress activated protein kinase signaling cascadeGO:0031098550.052
Fly
regulation of jnk cascadeGO:0046328400.052
Fly
regulation of circadian sleep wake cycleGO:0042749250.051
Rat
regulation of immune effector processGO:0002697520.051
Mouse Fly
negative regulation of signal transductionGO:00099682060.050
Fly
response to lipidGO:0033993380.049
Fly
regulation of antimicrobial peptide productionGO:0002784440.048
Fly
response to peptidoglycanGO:003249420.047
Fly
positive regulation of cellular biosynthetic processGO:00313283160.047
Fly
cellular response to biotic stimulusGO:007121640.047
Fly
negative regulation of multicellular organismal processGO:00512411420.045
Mouse
regulation of cellular response to stressGO:0080135890.045
Fly
appendage developmentGO:00487364010.045
interspecies interaction between organismsGO:0044419160.044
Mouse
homeostatic processGO:00425921990.043
stress activated mapk cascadeGO:0051403520.043
Fly
vesicle mediated transportGO:00161923810.042
negative regulation of cell differentiationGO:00455961430.042
Mouse
defense response to fungusGO:0050832480.042
response to organonitrogen compoundGO:0010243750.041
Fly
small molecule metabolic processGO:00442813050.039
regulation of phosphorylationGO:00423251470.039
Fly
hematopoietic or lymphoid organ developmentGO:0048534570.039
Mouse
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281630.038
Fly
imaginal disc derived wing morphogenesisGO:00074763370.038
cellular catabolic processGO:00442483720.038
negative regulation of developmental processGO:00510932010.036
Mouse
regionalizationGO:00030024160.036
negative regulation of stress activated protein kinase signaling cascadeGO:0070303200.036
Fly
post embryonic appendage morphogenesisGO:00351203850.034
imaginal disc derived appendage morphogenesisGO:00351143950.033
imaginal disc derived appendage developmentGO:00487373990.033
l amino acid importGO:004309220.033
appendage morphogenesisGO:00351073970.033
positive regulation of signal transductionGO:00099672230.033
wing disc morphogenesisGO:00074723440.032
negative regulation of phosphorus metabolic processGO:0010563450.032
Fly
regulation of anatomical structure sizeGO:00900661630.031
positive regulation of immune system processGO:0002684680.031
Human Fly
negative regulation of intracellular signal transductionGO:1902532570.031
Fly
organic hydroxy compound metabolic processGO:1901615830.031
Fly
epithelial cell differentiationGO:00308553220.030
regulation of localizationGO:00328792750.030
negative regulation of phosphate metabolic processGO:0045936450.029
Fly
phagocytosisGO:00069092150.028
regulation of melanization defense responseGO:003500760.028
Fly
carboxylic acid metabolic processGO:0019752920.028
ovarian follicle cell developmentGO:00307072480.028
negative regulation of mapk cascadeGO:0043409230.028
Fly
organic acid metabolic processGO:00060821030.028
negative regulation of innate immune responseGO:0045824300.028
compound eye developmentGO:00487493070.027
oxoacid metabolic processGO:00434361030.027
epithelial cell developmentGO:00020642740.027
establishment of localization in cellGO:00516494020.027
body morphogenesisGO:001017120.026
cell deathGO:00082192790.026
cell proliferationGO:00082832990.026
columnar cuboidal epithelial cell developmentGO:00020662490.026
cellular response to chemical stimulusGO:00708871990.026
Fly
developmental growthGO:00485892800.025
regulation of peptidoglycan recognition protein signaling pathwayGO:006105840.025
Fly
response to fungusGO:0009620500.025
taxisGO:00423303040.025
eye developmentGO:00016543230.025
single organism catabolic processGO:00447122280.025
organelle fissionGO:00482853400.025
nuclear divisionGO:00002803320.024
cell migrationGO:00164772380.024
axon developmentGO:00615642970.024
columnar cuboidal epithelial cell differentiationGO:00020652560.024
response to extracellular stimulusGO:00099911160.024
axon guidanceGO:00074112330.024
morphogenesis of an epitheliumGO:00020092760.023
neurological system processGO:00508773580.023
single organism biosynthetic processGO:00447112060.023
cellular response to lipidGO:0071396200.023
Fly
tissue morphogenesisGO:00487292970.022
regulation of response to biotic stimulusGO:0002831630.022
Fly
negative regulation of gene expressionGO:00106293870.022
deathGO:00162652840.022
macromolecule catabolic processGO:00090571610.022
chemotaxisGO:00069352490.022
organic cyclic compound catabolic processGO:19013611680.022
regulation of transportGO:00510491810.021
vitamin biosynthetic processGO:000911010.021
protein localizationGO:00081042840.021
forebrain developmentGO:003090020.021
compound eye morphogenesisGO:00017452490.021
eye morphogenesisGO:00485922600.021
melanization defense responseGO:0035006450.021
Fly
endocytosisGO:00068973100.021
salivary gland developmentGO:00074311620.021
response to nutrient levelsGO:00316671140.020
anatomical structure homeostasisGO:0060249970.020
matingGO:00076181200.020
hemopoiesisGO:0030097460.020
Mouse
xenobiotic catabolic processGO:004217810.020
protein modification processGO:00362114380.020
regulation of cell cycleGO:00517262910.020
aromatic compound catabolic processGO:00194391660.020
cellular amino acid metabolic processGO:0006520610.019
organic substance transportGO:00717022570.019
Fly
steroid catabolic processGO:000670610.019
positive regulation of innate immune responseGO:0045089380.019
Human Fly
macromolecular complex assemblyGO:00650032560.019
ethanolamine containing compound metabolic processGO:004243940.019
response to hexoseGO:000974630.019
response to monosaccharideGO:003428440.019
response to organophosphorusGO:004668320.018
regulation of growthGO:00400082330.018
programmed cell deathGO:00125012570.018
anion homeostasisGO:005508130.017
epithelium migrationGO:00901321480.017
positive regulation of cell communicationGO:00106472500.017
cytoplasmic transportGO:00164821300.017
regulation of sequestering of triglycerideGO:001088930.017
exocrine system developmentGO:00352721620.017
regulation of developmental growthGO:00486381740.017
regulation of cell proliferationGO:00421271630.017
cellular amine metabolic processGO:0044106120.017
cholesterol transportGO:003030120.016
connective tissue developmentGO:006144830.016
cellular ketone metabolic processGO:0042180240.016
histolysisGO:00075591020.016
sterol homeostasisGO:005509240.016
regulation of cellular amine metabolic processGO:003323830.016
regulation of cellular ketone metabolic processGO:001056530.016
locomotory behaviorGO:00076261760.016
tissue migrationGO:00901301550.016
chaeta developmentGO:0022416970.016
ion transportGO:00068111450.016
organophosphate metabolic processGO:00196371950.016
regulation of mapk cascadeGO:0043408920.016
Fly
nucleobase containing compound catabolic processGO:00346551650.016
sensory perception of chemical stimulusGO:00076061160.016
fat soluble vitamin metabolic processGO:000677510.016
cellular response to dna damage stimulusGO:00069742230.016
ribonucleotide metabolic processGO:00092591450.015
cholesterol homeostasisGO:004263230.015
intracellular transportGO:00469072280.015
single organism intracellular transportGO:19025822070.015
cell divisionGO:00513012480.015
response to abiotic stimulusGO:00096283410.015
cell motilityGO:00488702510.015
developmental maturationGO:00217001720.015
cellular response to oxygen containing compoundGO:1901701790.015
Fly
multi organism behaviorGO:00517051750.015
activation of innate immune responseGO:000221840.015
Human Fly
fat soluble vitamin biosynthetic processGO:004236210.015
response to copper ionGO:004668840.015
regulation of phosphorus metabolic processGO:00511742100.015
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.015
regulation of protein metabolic processGO:00512462560.015
axis specificationGO:00097981670.015
neuron projection guidanceGO:00974852410.015
ribonucleoside metabolic processGO:00091191270.014
amine metabolic processGO:0009308120.014
lateral inhibitionGO:00463312060.014
telencephalon developmentGO:002153720.014
tissue deathGO:00162711020.014
vitamin metabolic processGO:000676620.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
cellular macromolecule localizationGO:00707272200.014
cellular protein modification processGO:00064644380.014
cell recognitionGO:00080371020.014
carbohydrate derivative catabolic processGO:19011361180.014
purine nucleotide metabolic processGO:00061631460.014
glycosyl compound metabolic processGO:19016571270.014
organophosphate catabolic processGO:00464341120.014
salivary gland histolysisGO:0035070880.014
cellular response to organic substanceGO:00713101320.014
Fly
ameboidal type cell migrationGO:00016671510.014
positive regulation of developmental processGO:00510941430.014
gland developmentGO:00487321910.013
negative regulation of multi organism processGO:0043901290.013
Fly
tube developmentGO:00352952440.013
response to starvationGO:0042594970.013
positive regulation of intracellular signal transductionGO:19025331160.013
negative regulation of cellular biosynthetic processGO:00313272770.013
positive regulation of cellular amide metabolic processGO:0034250260.013
Fly
regulation of cell deathGO:00109411730.013
camera type eye developmentGO:004301040.013
transcription from rna polymerase ii promoterGO:00063663680.013
localization of cellGO:00516742570.013
positive regulation of macromolecule metabolic processGO:00106044050.013
jak stat cascadeGO:0007259490.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
heterocycle catabolic processGO:00467001660.013
gland morphogenesisGO:00226121450.013
response to glucoseGO:000974920.013
regulation of catabolic processGO:00098941700.013
oocyte differentiationGO:00099941450.013
negative regulation of stress activated mapk cascadeGO:0032873190.013
Fly
ribose phosphate metabolic processGO:00196931450.013
salivary gland cell autophagic cell deathGO:0035071830.013
androgen metabolic processGO:000820910.013
leucine transportGO:001582030.013
circadian rhythmGO:00076231050.013
Rat
lipid metabolic processGO:00066291210.013
positive regulation of multicellular organismal processGO:00512401430.013
glycerolipid catabolic processGO:004650330.013
maintenance of locationGO:0051235730.013
synapse organizationGO:00508081960.013
regulation of cellular component biogenesisGO:00440872010.012
rna localizationGO:00064031150.012
developmental programmed cell deathGO:00106231380.012
ovarian follicle cell migrationGO:00072971210.012
activation of immune responseGO:000225350.012
Human Fly
protein maturationGO:0051604710.012
small gtpase mediated signal transductionGO:0007264880.012
stem cell divisionGO:0017145690.012
regulation of cell cycle processGO:00105641810.012
cellular response to ethanolGO:007136140.012
multicellular organismal homeostasisGO:0048871410.012
positive regulation of lipid storageGO:001088440.012
benzene containing compound metabolic processGO:004253730.012
apoptotic processGO:00069151590.012
cellular macromolecular complex assemblyGO:00346221530.012
multi multicellular organism processGO:00447061230.012
cation transmembrane transportGO:0098655880.012
blastoderm segmentationGO:00073501590.012
response to temperature stimulusGO:00092661060.012
regulation of cellular amino acid metabolic processGO:000652100.012
epithelial cell migrationGO:00106311480.012
regulation of cell cycle phase transitionGO:19019871300.012
regulation of anatomical structure morphogenesisGO:00226032420.012
single organism cellular localizationGO:19025801800.012
posttranscriptional regulation of gene expressionGO:00106081450.012
agingGO:00075681430.012
Fly
positive regulation of cell motilityGO:200014730.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
limb developmentGO:006017310.012
gene silencingGO:00164581380.012
purine containing compound catabolic processGO:00725231120.012
positive regulation of growthGO:0045927750.012
neurotransmitter metabolic processGO:004213320.012
regulation of cellular protein metabolic processGO:00322682430.012
cell cell signaling involved in cell fate commitmentGO:00451682100.012
nucleoside phosphate catabolic processGO:19012921100.012
purine nucleotide catabolic processGO:00061951090.012
mitotic nuclear divisionGO:00070672130.012
estrogen metabolic processGO:000821010.012
regulation of cellular localizationGO:00603411360.012
aminoglycan catabolic processGO:000602660.012
cellular response to endogenous stimulusGO:0071495800.011
border follicle cell migrationGO:00072981130.011
negative regulation of transcription dna templatedGO:00458922370.011
positive regulation of cell migrationGO:003033520.011
positive regulation of gene expressionGO:00106282900.011
regulation of cellular component sizeGO:0032535980.011
cellular protein localizationGO:00346131600.011
embryonic pattern specificationGO:00098801740.011
oocyte constructionGO:00073081120.011
establishment of protein localizationGO:00451841630.011
carbohydrate derivative biosynthetic processGO:1901137850.011
long term memoryGO:0007616620.011
ribonucleotide catabolic processGO:00092611090.011
ion transmembrane transportGO:00342201220.011
leucine importGO:006035630.011
l glutamate importGO:005193810.011
antibacterial humoral responseGO:0019731440.011
Fly
regulation of programmed cell deathGO:00430671520.011
respiratory system developmentGO:00605412130.011
oocyte developmentGO:00485991240.011
cellular component assembly involved in morphogenesisGO:00109271510.011
innate immune response activating signal transductionGO:000275820.011
Human Fly
ras protein signal transductionGO:0007265880.011
kidney developmentGO:000182230.011
spermatogenesisGO:00072832000.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
nucleoside metabolic processGO:00091161270.011
acid secretionGO:004671710.011
nucleotide catabolic processGO:00091661090.011
negative regulation of rna metabolic processGO:00512532510.011
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.011
endomembrane system organizationGO:00102561190.011
wound healingGO:0042060750.011
positive regulation of signalingGO:00230562430.011
toxin catabolic processGO:000940710.011
phospholipid homeostasisGO:005509110.011
dorsal ventral pattern formationGO:00099531330.011
mrna metabolic processGO:00160711240.011
glycosyl compound catabolic processGO:19016581120.011
chromosome organizationGO:00512763600.011
oocyte axis specificationGO:00073091080.011
autophagic cell deathGO:0048102830.011
photoreceptor cell differentiationGO:00465301700.011
cellular nitrogen compound catabolic processGO:00442701650.011
cell adhesionGO:00071551360.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
salivary gland morphogenesisGO:00074351450.011
wnt signaling pathwayGO:0016055980.011
regulation of molecular functionGO:00650092170.011
rna processingGO:00063961470.011
spindle organizationGO:00070512530.011
mapk cascadeGO:00001651070.011
Fly
proteolysisGO:00065081920.011
synaptic transmissionGO:00072682880.011
eye antennal disc developmentGO:0035214600.011
axonogenesisGO:00074092900.011
biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281530.011
Fly
positive regulation of phosphorus metabolic processGO:00105621390.011
hindbrain developmentGO:003090220.011
monocarboxylic acid transportGO:001571830.011
response to oxidative stressGO:0006979860.011
purine containing compound metabolic processGO:00725211550.011
cation transportGO:00068121100.010
regulation of mitotic cell cycle phase transitionGO:19019901300.010
chromosome segregationGO:00070591570.010
cellular macromolecule catabolic processGO:00442651360.010
acylglycerol biosynthetic processGO:004646320.010
medium chain fatty acid metabolic processGO:005179110.010
limb morphogenesisGO:003510810.010
positive regulation of nucleic acid templated transcriptionGO:19035082660.010
nucleoside phosphate metabolic processGO:00067531620.010
protein phosphorylationGO:00064681690.010
nucleoside triphosphate catabolic processGO:00091431080.010
segmentationGO:00352822070.010
nucleoside triphosphate metabolic processGO:00091411200.010
skeletal muscle fiber developmentGO:004874130.010
response to inorganic substanceGO:0010035440.010
muscle structure developmentGO:00610612240.010
convergent extensionGO:006002620.010
nitrogen compound transportGO:0071705850.010
Fly
anterior posterior axis specificationGO:00099481090.010
regulation of antibacterial peptide biosynthetic processGO:0002808220.010
Fly
cellular response to carbohydrate stimulusGO:007132240.010
regulation of mitotic cell cycleGO:00073461900.010
spinal cord developmentGO:002151010.010
positive regulation of transportGO:0051050920.010
regulation of nervous system developmentGO:00519602480.010

PGRP-SC1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.017
acquired metabolic diseaseDOID:006015800.017
nervous system diseaseDOID:86300.016
cardiovascular system diseaseDOID:128700.014
artery diseaseDOID:005082800.013
vascular diseaseDOID:17800.013
hypertensionDOID:1076300.013
type 2 diabetes mellitusDOID:935200.013
carbohydrate metabolism diseaseDOID:005001300.013
glucose metabolism diseaseDOID:419400.013
diabetes mellitusDOID:935100.013
lipid metabolism disorderDOID:314600.011
familial combined hyperlipidemiaDOID:1380900.011
familial hyperlipidemiaDOID:116800.011