IMP: Integrative Multi-species Prediction

Drosophila melanogaster

98 known processes

Anp (Dmel_CG1361)

Andropin

(Aliases: And,Cec,CG1361,CEC,Dmel\CG1361,k-9)

Entrez: 43595
FLYBASE: FBgn0000094
UniProtKB: P21663

Process Predictions
Disease Predictions

Anp biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
mating	GO:0007618	120	0.074
insemination	GO:0007320	22	0.063
sperm competition	GO:0046692	21	0.057
sperm storage	GO:0046693	10	0.050
multi organism behavior	GO:0051705	175	0.047
small molecule metabolic process	GO:0044281	305	0.040
mating behavior	GO:0007617	106	0.039
response to biotic stimulus	GO:0009607	294	0.037
carboxylic acid metabolic process	GO:0019752	92	0.034
regulation of female receptivity	GO:0045924	24	0.034
vesicle mediated transport	GO:0016192	381	0.034
organic acid metabolic process	GO:0006082	103	0.031
multicellular organismal reproductive behavior	GO:0033057	110	0.030
body morphogenesis	GO:0010171	2	0.030
endocytosis	GO:0006897	310	0.029
female mating behavior	GO:0060180	30	0.028
response to external biotic stimulus	GO:0043207	293	0.028
g protein coupled receptor signaling pathway	GO:0007186	136	0.028
cellular catabolic process	GO:0044248	372	0.027
response to abiotic stimulus	GO:0009628	341	0.027
response to other organism	GO:0051707	293	0.026
negative regulation of gene expression	GO:0010629	387	0.025
death	GO:0016265	284	0.025
appendage development	GO:0048736	401	0.025
regionalization	GO:0003002	416	0.024
defense response to bacterium	GO:0042742	178	0.024
regulation of multicellular organismal development	GO:2000026	414	0.024
appendage morphogenesis	GO:0035107	397	0.023
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.023
imaginal disc derived appendage development	GO:0048737	399	0.023
multi organism reproductive behavior	GO:0044705	121	0.023
negative regulation of cellular metabolic process	GO:0031324	382	0.023
adult behavior	GO:0030534	137	0.023
epithelial cell differentiation	GO:0030855	322	0.022
reproductive behavior	GO:0019098	122	0.022
programmed cell death	GO:0012501	257	0.022
catabolic process	GO:0009056	409	0.022
single organism biosynthetic process	GO:0044711	206	0.022
regulation of multi organism process	GO:0043900	131	0.022
regulation of molecular function	GO:0065009	217	0.021
response to organic substance	GO:0010033	284	0.021
regulation of female receptivity post mating	GO:0046008	17	0.021
spermatogenesis	GO:0007283	200	0.021
organic substance catabolic process	GO:1901575	308	0.021
protein modification process	GO:0036211	438	0.021
developmental growth	GO:0048589	280	0.021
neurological system process	GO:0050877	358	0.021
phagocytosis	GO:0006909	215	0.021
response to lipopolysaccharide	GO:0032496	4	0.021
regulation of cellular ketone metabolic process	GO:0010565	3	0.021
positive regulation of response to stimulus	GO:0048584	323	0.021
negative regulation of female receptivity	GO:0007621	14	0.020
regulation of cellular protein metabolic process	GO:0032268	243	0.020
organophosphate metabolic process	GO:0019637	195	0.020
very long chain fatty acid metabolic process	GO:0000038	4	0.020
imaginal disc derived wing morphogenesis	GO:0007476	337	0.020
wing disc morphogenesis	GO:0007472	344	0.020
response to oxygen containing compound	GO:1901700	200	0.020
regulation of protein metabolic process	GO:0051246	256	0.020
regulation of cell differentiation	GO:0045595	302	0.020
cell death	GO:0008219	279	0.019
forebrain development	GO:0030900	2	0.019
compound eye development	GO:0048749	307	0.019
cholesterol homeostasis	GO:0042632	3	0.019
cellular ketone metabolic process	GO:0042180	24	0.019
post embryonic appendage morphogenesis	GO:0035120	385	0.019
response to bacterium	GO:0009617	198	0.019
regulation of cell cycle	GO:0051726	291	0.019
single organism behavior	GO:0044708	391	0.019
regulation of cellular amine metabolic process	GO:0033238	3	0.019
establishment of localization in cell	GO:0051649	402	0.019
positive regulation of cell communication	GO:0010647	250	0.019
defense response	GO:0006952	300	0.019
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.018
regulation of catalytic activity	GO:0050790	185	0.018
regulation of cellular amino acid metabolic process	GO:0006521	0	0.018
fatty acid elongation	GO:0030497	3	0.018
taxis	GO:0042330	304	0.018
regulation of localization	GO:0032879	275	0.018
defense response to other organism	GO:0098542	225	0.018
salivary gland development	GO:0007431	162	0.018
negative regulation of signaling	GO:0023057	219	0.018
amine metabolic process	GO:0009308	12	0.018
spindle organization	GO:0007051	253	0.017
response to hexose	GO:0009746	3	0.017
response to monosaccharide	GO:0034284	4	0.017
cellular protein modification process	GO:0006464	438	0.017
cell division	GO:0051301	248	0.017
negative regulation of developmental process	GO:0051093	201	0.017
protein localization	GO:0008104	284	0.017
cellular amino acid metabolic process	GO:0006520	61	0.017
photoreceptor cell differentiation	GO:0046530	170	0.017
homeostatic process	GO:0042592	199	0.017
organic substance transport	GO:0071702	257	0.017
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.017
positive regulation of cellular biosynthetic process	GO:0031328	316	0.017
negative regulation of cell communication	GO:0010648	223	0.016
carbohydrate derivative metabolic process	GO:1901135	217	0.016
organic cyclic compound catabolic process	GO:1901361	168	0.016
phosphorylation	GO:0016310	294	0.016
regulation of proteolysis	GO:0030162	87	0.016
antimicrobial humoral response	GO:0019730	99	0.016
aromatic compound catabolic process	GO:0019439	166	0.016
male gamete generation	GO:0048232	201	0.016
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.016
transcription from rna polymerase ii promoter	GO:0006366	368	0.016
single organism catabolic process	GO:0044712	228	0.016
ribonucleotide metabolic process	GO:0009259	145	0.016
macromolecular complex assembly	GO:0065003	256	0.016
intracellular signal transduction	GO:0035556	300	0.016
camera type eye development	GO:0043010	4	0.016
telencephalon development	GO:0021537	2	0.016
negative regulation of biosynthetic process	GO:0009890	277	0.015
epithelial cell development	GO:0002064	274	0.015
regulation of cellular catabolic process	GO:0031329	157	0.015
positive regulation of signal transduction	GO:0009967	223	0.015
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.015
anion homeostasis	GO:0055081	3	0.015
ribose phosphate metabolic process	GO:0019693	145	0.015
sensory perception of chemical stimulus	GO:0007606	116	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.015
proteolysis	GO:0006508	192	0.015
segmentation	GO:0035282	207	0.015
biological adhesion	GO:0022610	138	0.015
ovarian follicle cell development	GO:0030707	248	0.015
gland development	GO:0048732	191	0.015
single organism intracellular transport	GO:1902582	207	0.015
organelle fission	GO:0048285	340	0.015
multi multicellular organism process	GO:0044706	123	0.015
cellular nitrogen compound catabolic process	GO:0044270	165	0.015
eye morphogenesis	GO:0048592	260	0.015
negative regulation of cellular biosynthetic process	GO:0031327	277	0.015
immune response	GO:0006955	246	0.014
developmental programmed cell death	GO:0010623	138	0.014
eye development	GO:0001654	323	0.014
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.014
positive regulation of signaling	GO:0023056	243	0.014
regulation of production of molecular mediator of immune response	GO:0002700	44	0.014
open tracheal system development	GO:0007424	204	0.014
compound eye morphogenesis	GO:0001745	249	0.014
chromosome organization	GO:0051276	360	0.014
negative regulation of rna metabolic process	GO:0051253	251	0.014
regulation of catabolic process	GO:0009894	170	0.014
regulation of organelle organization	GO:0033043	196	0.014
nuclear division	GO:0000280	332	0.014
positive regulation of biosynthetic process	GO:0009891	316	0.014
response to organophosphorus	GO:0046683	2	0.014
columnar cuboidal epithelial cell development	GO:0002066	249	0.014
heterocycle catabolic process	GO:0046700	166	0.014
respiratory system development	GO:0060541	213	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.014
dna metabolic process	GO:0006259	227	0.014
positive regulation of cell motility	GO:2000147	3	0.014
sterol homeostasis	GO:0055092	4	0.014
kidney development	GO:0001822	3	0.014
multicellular organismal aging	GO:0010259	140	0.014
nucleoside phosphate metabolic process	GO:0006753	162	0.014
membrane organization	GO:0061024	112	0.014
morphogenesis of an epithelium	GO:0002009	276	0.014
negative regulation of response to stimulus	GO:0048585	258	0.013
cellular response to dna damage stimulus	GO:0006974	223	0.013
nucleotide metabolic process	GO:0009117	161	0.013
regulation of mitotic cell cycle	GO:0007346	190	0.013
organonitrogen compound biosynthetic process	GO:1901566	117	0.013
mitotic nuclear division	GO:0007067	213	0.013
immune system process	GO:0002376	347	0.013
response to alcohol	GO:0097305	95	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.013
eye photoreceptor cell differentiation	GO:0001754	145	0.013
oxoacid metabolic process	GO:0043436	103	0.013
mitotic spindle organization	GO:0007052	220	0.013
regulation of transport	GO:0051049	181	0.013
negative regulation of rna biosynthetic process	GO:1902679	240	0.013
connective tissue development	GO:0061448	3	0.013
regulation of behavior	GO:0050795	75	0.013
very long chain fatty acid biosynthetic process	GO:0042761	2	0.013
nucleobase containing small molecule metabolic process	GO:0055086	174	0.013
regulation of hydrolase activity	GO:0051336	97	0.013
intracellular transport	GO:0046907	228	0.013
growth	GO:0040007	359	0.013
gene silencing	GO:0016458	138	0.013
regulation of cell death	GO:0010941	173	0.013
cellular amine metabolic process	GO:0044106	12	0.013
regulation of notch signaling pathway	GO:0008593	100	0.013
antimicrobial peptide production	GO:0002775	46	0.013
actin cytoskeleton organization	GO:0030036	206	0.013
l amino acid import	GO:0043092	2	0.013
negative regulation of cell differentiation	GO:0045596	143	0.013
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.013
mitotic cell cycle phase transition	GO:0044772	138	0.013
retina development in camera type eye	GO:0060041	4	0.013
dorsal ventral pattern formation	GO:0009953	133	0.013
long chain fatty acid metabolic process	GO:0001676	3	0.013
response to radiation	GO:0009314	155	0.013
ion transport	GO:0006811	145	0.013
immune response activating signal transduction	GO:0002757	2	0.013
positive regulation of phosphorus metabolic process	GO:0010562	139	0.013
ras protein signal transduction	GO:0007265	88	0.013
compound eye photoreceptor cell differentiation	GO:0001751	140	0.013
regulation of immune system process	GO:0002682	176	0.013
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.013
embryonic pattern specification	GO:0009880	174	0.012
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.012
exocrine system development	GO:0035272	162	0.012
axis specification	GO:0009798	167	0.012
sensory organ morphogenesis	GO:0090596	260	0.012
positive regulation of cell migration	GO:0030335	2	0.012
nucleobase containing compound catabolic process	GO:0034655	165	0.012
regulation of programmed cell death	GO:0043067	152	0.012
apoptotic process	GO:0006915	159	0.012
response to temperature stimulus	GO:0009266	106	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
secondary metabolic process	GO:0019748	75	0.012
negative regulation of signal transduction	GO:0009968	206	0.012
regulation of intracellular signal transduction	GO:1902531	236	0.012
developmental maturation	GO:0021700	172	0.012
regulation of anatomical structure morphogenesis	GO:0022603	242	0.012
positive regulation of macromolecule metabolic process	GO:0010604	405	0.012
positive regulation of phosphate metabolic process	GO:0045937	139	0.012
small gtpase mediated signal transduction	GO:0007264	88	0.012
photoreceptor cell development	GO:0042461	96	0.012
nucleoside phosphate catabolic process	GO:1901292	110	0.012
cellular response to chemical stimulus	GO:0070887	199	0.012
salivary gland cell autophagic cell death	GO:0035071	83	0.012
localization of cell	GO:0051674	257	0.012
response to nutrient levels	GO:0031667	114	0.012
macromolecule catabolic process	GO:0009057	161	0.012
autophagic cell death	GO:0048102	83	0.012
regulation of developmental growth	GO:0048638	174	0.012
protein complex biogenesis	GO:0070271	201	0.012
regulation of response to external stimulus	GO:0032101	115	0.012
blastoderm segmentation	GO:0007350	159	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
embryonic axis specification	GO:0000578	107	0.012
cell adhesion	GO:0007155	136	0.012
positive regulation of catabolic process	GO:0009896	105	0.012
protein complex assembly	GO:0006461	200	0.012
positive regulation of catalytic activity	GO:0043085	118	0.012
histolysis	GO:0007559	102	0.012
cellular lipid metabolic process	GO:0044255	83	0.012
salivary gland histolysis	GO:0035070	88	0.012
chromosome segregation	GO:0007059	157	0.012
secretion by cell	GO:0032940	101	0.012
endomembrane system organization	GO:0010256	119	0.012
positive regulation of molecular function	GO:0044093	136	0.012
organonitrogen compound catabolic process	GO:1901565	128	0.012
actin filament based process	GO:0030029	220	0.012
cell proliferation	GO:0008283	299	0.012
regulation of response to stress	GO:0080134	200	0.011
sensory perception of salty taste	GO:0050914	3	0.011
regulation of phosphate metabolic process	GO:0019220	210	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.011
sensory perception	GO:0007600	196	0.011
tube morphogenesis	GO:0035239	191	0.011
chaeta development	GO:0022416	97	0.011
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
tissue death	GO:0016271	102	0.011
cell migration	GO:0016477	238	0.011
negative regulation of transcription dna templated	GO:0045892	237	0.011
organophosphate catabolic process	GO:0046434	112	0.011
salivary gland morphogenesis	GO:0007435	145	0.011
purine nucleoside metabolic process	GO:0042278	127	0.011
regulation of reproductive process	GO:2000241	54	0.011
cellular macromolecular complex assembly	GO:0034622	153	0.011
somatic muscle development	GO:0007525	66	0.011
mesenchymal cell differentiation	GO:0048762	1	0.011
cellular response to molecule of bacterial origin	GO:0071219	3	0.011
cellular response to lipopolysaccharide	GO:0071222	3	0.011
notch signaling pathway	GO:0007219	120	0.011
lipopolysaccharide mediated signaling pathway	GO:0031663	1	0.011
embryonic development via the syncytial blastoderm	GO:0001700	148	0.011
organelle assembly	GO:0070925	198	0.011
carbohydrate derivative catabolic process	GO:1901136	118	0.011
production of molecular mediator of immune response	GO:0002440	46	0.011
establishment of protein localization	GO:0045184	163	0.011
ethanolamine containing compound metabolic process	GO:0042439	4	0.011
regulation of anatomical structure size	GO:0090066	163	0.011
gland morphogenesis	GO:0022612	145	0.011
defense response to gram negative bacterium	GO:0050829	94	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.011
monocarboxylic acid transport	GO:0015718	3	0.011
nucleoside metabolic process	GO:0009116	127	0.011
lateral inhibition	GO:0046331	206	0.011
chromatin remodeling	GO:0006338	72	0.011
hormone catabolic process	GO:0042447	3	0.011
regulation of cellular localization	GO:0060341	136	0.011
posttranscriptional regulation of gene expression	GO:0010608	145	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.011
cellular macromolecule catabolic process	GO:0044265	136	0.011
protein maturation	GO:0051604	71	0.011
negative regulation of female receptivity post mating	GO:0045434	12	0.011
humoral immune response	GO:0006959	117	0.011
positive regulation of cellular catabolic process	GO:0031331	95	0.011
secondary metabolite biosynthetic process	GO:0044550	24	0.010
purine ribonucleoside metabolic process	GO:0046128	127	0.010
central nervous system development	GO:0007417	201	0.010
rna processing	GO:0006396	147	0.010
single organism carbohydrate metabolic process	GO:0044723	72	0.010
ribonucleoside metabolic process	GO:0009119	127	0.010
regulation of antimicrobial humoral response	GO:0002759	50	0.010
protein phosphorylation	GO:0006468	169	0.010
purine containing compound metabolic process	GO:0072521	155	0.010
behavioral response to ethanol	GO:0048149	49	0.010
cell motility	GO:0048870	251	0.010
ribonucleoside catabolic process	GO:0042454	112	0.010
chemosensory behavior	GO:0007635	106	0.010
regulation of gene expression epigenetic	GO:0040029	128	0.010
limb development	GO:0060173	1	0.010
detection of stimulus	GO:0051606	156	0.010
single organism cellular localization	GO:1902580	180	0.010
purine ribonucleotide metabolic process	GO:0009150	145	0.010
cell cycle phase transition	GO:0044770	140	0.010
organonitrogen compound metabolic process	GO:1901564	318	0.010
purine containing compound catabolic process	GO:0072523	112	0.010
positive regulation of transport	GO:0051050	92	0.010
camera type eye morphogenesis	GO:0048593	2	0.010
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.010
purine nucleotide catabolic process	GO:0006195	109	0.010
mesenchymal cell development	GO:0014031	1	0.010
protein heterooligomerization	GO:0051291	4	0.010
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.010
cellular amide metabolic process	GO:0043603	80	0.010
androgen metabolic process	GO:0008209	1	0.010
negative regulation of cellular protein metabolic process	GO:0032269	85	0.010
purine ribonucleotide catabolic process	GO:0009154	109	0.010
single organism membrane organization	GO:0044802	93	0.010
anterior posterior pattern specification	GO:0009952	136	0.010
negative regulation of protein metabolic process	GO:0051248	85	0.010
mitotic sister chromatid segregation	GO:0000070	87	0.010
tripartite regional subdivision	GO:0007351	103	0.010
chemical homeostasis	GO:0048878	92	0.010

Anp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.031
nervous system disease	DOID:863	0.023
inherited metabolic disorder	DOID:655	0.013
disease of metabolism	DOID:0014667	0.013
sensory system disease	DOID:0050155	0.013
eye and adnexa disease	DOID:1492	0.011
eye disease	DOID:5614	0.011
cardiovascular system disease	DOID:1287	0.011
carbohydrate metabolism disease	DOID:0050013	0.010
acquired metabolic disease	DOID:0060158	0.010
glucose metabolism disease	DOID:4194	0.010
diabetes mellitus	DOID:9351	0.010

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