Drosophila melanogaster

24 known processes

TotC (Dmel_CG31508)

Turandot C

(Aliases: TOTc,totC,CG31508,Dmel\CG31508,tot)

TotC biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to other organismGO:00517072930.061
response to biotic stimulusGO:00096072940.060
response to bacteriumGO:00096171980.059
response to external biotic stimulusGO:00432072930.042
defense responseGO:00069523000.041
positive regulation of response to stimulusGO:00485843230.041
response to organic substanceGO:00100332840.041
Fly
organonitrogen compound metabolic processGO:19015643180.040
cellular response to heatGO:0034605240.039
intracellular signal transductionGO:00355563000.035
response to oxygen containing compoundGO:19017002000.034
Fly
phosphorylationGO:00163102940.034
body morphogenesisGO:001017120.034
cellular response to chemical stimulusGO:00708871990.032
Fly
neurological system processGO:00508773580.032
innate immune responseGO:00450871440.031
defense response to other organismGO:00985422250.030
single organism behaviorGO:00447083910.030
regulation of intracellular signal transductionGO:19025312360.030
positive regulation of macromolecule metabolic processGO:00106044050.029
organic substance catabolic processGO:19015753080.029
response to lipopolysaccharideGO:003249640.028
lateral inhibitionGO:00463312060.028
organic substance transportGO:00717022570.028
positive regulation of nitrogen compound metabolic processGO:00511733540.028
catabolic processGO:00090564090.027
response to temperature stimulusGO:00092661060.027
defense response to bacteriumGO:00427421780.026
endocytosisGO:00068973100.025
immune responseGO:00069552460.025
response to abiotic stimulusGO:00096283410.025
compound eye developmentGO:00487493070.024
vesicle mediated transportGO:00161923810.024
eye developmentGO:00016543230.024
regulation of multicellular organismal developmentGO:20000264140.024
immune response regulating signaling pathwayGO:000276420.023
cell deathGO:00082192790.023
organic acid metabolic processGO:00060821030.023
protein modification processGO:00362114380.023
cellular response to radiationGO:0071478520.023
cellular amino acid metabolic processGO:0006520610.023
chorion containing eggshell formationGO:00073041050.023
positive regulation of cellular biosynthetic processGO:00313283160.022
cellular protein modification processGO:00064644380.022
sensory perceptionGO:00076001960.022
imaginal disc derived wing morphogenesisGO:00074763370.022
carboxylic acid metabolic processGO:0019752920.022
eye morphogenesisGO:00485922600.021
macromolecule catabolic processGO:00090571610.021
imaginal disc derived appendage morphogenesisGO:00351143950.021
cellular catabolic processGO:00442483720.021
epithelial cell differentiationGO:00308553220.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
compound eye morphogenesisGO:00017452490.021
immune response activating signal transductionGO:000275720.020
regulation of cellular ketone metabolic processGO:001056530.020
immune system processGO:00023763470.020
cell proliferationGO:00082832990.020
regulation of immune responseGO:00507761180.020
appendage developmentGO:00487364010.020
camera type eye developmentGO:004301040.020
sensory organ morphogenesisGO:00905962600.020
regulation of phosphorus metabolic processGO:00511742100.020
humoral immune responseGO:00069591170.020
regulation of cellular amino acid metabolic processGO:000652100.019
cellular response to lipopolysaccharideGO:007122230.019
negative regulation of cellular metabolic processGO:00313243820.019
oxoacid metabolic processGO:00434361030.019
phagocytosisGO:00069092150.019
programmed cell deathGO:00125012570.019
positive regulation of gene expressionGO:00106282900.019
cellular component assembly involved in morphogenesisGO:00109271510.019
establishment of localization in cellGO:00516494020.019
response to mercury ionGO:004668930.019
Fly
regulation of cell cycleGO:00517262910.019
mitotic cell cycle phase transitionGO:00447721380.019
regulation of response to stressGO:00801342000.019
positive regulation of cell communicationGO:00106472500.019
homeostatic processGO:00425921990.019
cellular response to molecule of bacterial originGO:007121930.018
positive regulation of nucleobase containing compound metabolic processGO:00459353320.018
steroid catabolic processGO:000670610.018
carbohydrate derivative metabolic processGO:19011352170.018
deathGO:00162652840.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
appendage morphogenesisGO:00351073970.018
organonitrogen compound biosynthetic processGO:19015661170.018
single organism catabolic processGO:00447122280.017
regulation of defense responseGO:00313471020.017
lipopolysaccharide mediated signaling pathwayGO:003166310.017
positive regulation of signal transductionGO:00099672230.017
positive regulation of biosynthetic processGO:00098913160.017
forebrain developmentGO:003090020.017
single organism biosynthetic processGO:00447112060.017
regulation of protein metabolic processGO:00512462560.017
small molecule metabolic processGO:00442813050.017
transcription from rna polymerase ii promoterGO:00063663680.017
negative regulation of response to stimulusGO:00485852580.017
regulation of cellular amine metabolic processGO:003323830.017
cell migrationGO:00164772380.017
agingGO:00075681430.017
chromosome organizationGO:00512763600.016
cellular response to dna damage stimulusGO:00069742230.016
cellular response to oxidative stressGO:0034599280.016
Fly
negative regulation of cell communicationGO:00106482230.016
spindle organizationGO:00070512530.016
kidney developmentGO:000182230.016
defense response to gram negative bacteriumGO:0050829940.016
epithelial cell developmentGO:00020642740.016
multicellular organismal agingGO:00102591400.016
wing disc morphogenesisGO:00074723440.016
proteolysisGO:00065081920.016
organonitrogen compound catabolic processGO:19015651280.016
positive regulation of signalingGO:00230562430.016
regulation of cellular protein metabolic processGO:00322682430.016
cellular response to abiotic stimulusGO:0071214580.016
response to organophosphorusGO:004668320.016
amine metabolic processGO:0009308120.016
cellular amine metabolic processGO:0044106120.016
cuticle developmentGO:0042335860.016
cellular macromolecule catabolic processGO:00442651360.016
cellular response to light stimulusGO:0071482370.016
imaginal disc derived appendage developmentGO:00487373990.016
determination of adult lifespanGO:00083401370.015
cell cycle phase transitionGO:00447701400.015
response to heatGO:0009408630.015
cellular response to biotic stimulusGO:007121640.015
cellular ketone metabolic processGO:0042180240.015
regulation of phosphorylationGO:00423251470.015
negative regulation of nitrogen compound metabolic processGO:00511722650.015
positive regulation of cell motilityGO:200014730.015
positive regulation of rna biosynthetic processGO:19026802660.015
ion transportGO:00068111450.015
developmental pigmentationGO:0048066680.015
regulation of multi organism processGO:00439001310.015
rna processingGO:00063961470.015
regulation of mitotic cell cycleGO:00073461900.015
response to light stimulusGO:00094161240.015
purine containing compound metabolic processGO:00725211550.015
axis specificationGO:00097981670.015
connective tissue developmentGO:006144830.015
organic cyclic compound catabolic processGO:19013611680.015
nucleobase containing small molecule metabolic processGO:00550861740.015
protein phosphorylationGO:00064681690.015
negative regulation of rna metabolic processGO:00512532510.015
growthGO:00400073590.015
post embryonic appendage morphogenesisGO:00351203850.015
negative regulation of developmental processGO:00510932010.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
taxisGO:00423303040.014
intracellular transportGO:00469072280.014
chemotaxisGO:00069352490.014
regulation of phosphate metabolic processGO:00192202100.014
chromosome segregationGO:00070591570.014
protein localizationGO:00081042840.014
regulation of mitotic cell cycle phase transitionGO:19019901300.014
response to radiationGO:00093141550.014
exocrine system developmentGO:00352721620.014
eye photoreceptor cell differentiationGO:00017541450.014
negative regulation of gene expressionGO:00106293870.014
regionalizationGO:00030024160.014
positive regulation of rna metabolic processGO:00512542710.014
regulation of localizationGO:00328792750.014
cellular response to organic substanceGO:00713101320.014
adult locomotory behaviorGO:0008344760.013
negative regulation of signalingGO:00230572190.013
organelle fissionGO:00482853400.013
cell divisionGO:00513012480.013
antimicrobial humoral responseGO:0019730990.013
dna metabolic processGO:00062592270.013
response to oxidative stressGO:0006979860.013
mrna metabolic processGO:00160711240.013
nuclear divisionGO:00002803320.013
mitotic nuclear divisionGO:00070672130.013
nucleoside phosphate metabolic processGO:00067531620.013
response to nutrient levelsGO:00316671140.013
negative regulation of biosynthetic processGO:00098902770.013
signal transduction by phosphorylationGO:00230141070.013
response to hexoseGO:000974630.013
regulation of immune system processGO:00026821760.013
positive regulation of phosphorus metabolic processGO:00105621390.013
cellular nitrogen compound catabolic processGO:00442701650.013
regulation of cell deathGO:00109411730.013
positive regulation of cell migrationGO:003033520.013
male gamete generationGO:00482322010.013
regulation of catalytic activityGO:00507901850.013
heterocycle catabolic processGO:00467001660.013
mitotic spindle organizationGO:00070522200.013
eggshell formationGO:00307031050.013
regulation of cellular component biogenesisGO:00440872010.013
regulation of synapse structure and activityGO:00508031280.013
developmental maturationGO:00217001720.013
macromolecular complex assemblyGO:00650032560.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
segmentationGO:00352822070.013
neuron projection guidanceGO:00974852410.013
hindbrain developmentGO:003090220.013
cellular macromolecule localizationGO:00707272200.013
autophagic cell deathGO:0048102830.013
regulation of molecular functionGO:00650092170.013
regulation of cell cycle phase transitionGO:19019871300.013
protein transportGO:00150311550.013
regulation of organelle organizationGO:00330431960.013
mapk cascadeGO:00001651070.013
negative regulation of signal transductionGO:00099682060.013
response to nitrogen compoundGO:1901698900.013
nitrogen compound transportGO:0071705850.013
immune effector processGO:0002252980.013
activation of innate immune responseGO:000221840.013
carbohydrate derivative catabolic processGO:19011361180.012
innate immune response activating signal transductionGO:000275820.012
regulation of cell cycle processGO:00105641810.012
ovarian follicle cell developmentGO:00307072480.012
detection of chemical stimulusGO:0009593930.012
establishment of protein localizationGO:00451841630.012
matingGO:00076181200.012
organelle assemblyGO:00709251980.012
single organism cellular localizationGO:19025801800.012
positive regulation of transcription dna templatedGO:00458932660.012
regulation of mapk cascadeGO:0043408920.012
positive regulation of macromolecule biosynthetic processGO:00105572830.012
regulation of cell morphogenesisGO:00226041630.012
protein complex biogenesisGO:00702712010.012
regulation of innate immune responseGO:0045088710.012
small gtpase mediated signal transductionGO:0007264880.012
detection of stimulusGO:00516061560.012
tissue deathGO:00162711020.012
tripartite regional subdivisionGO:00073511030.012
chromatin modificationGO:00165681470.012
single organism intracellular transportGO:19025822070.012
androgen metabolic processGO:000820910.012
regulation of anatomical structure morphogenesisGO:00226032420.012
response to organic cyclic compoundGO:0014070890.012
developmental growthGO:00485892800.012
salivary gland morphogenesisGO:00074351450.012
negative regulation of cellular biosynthetic processGO:00313272770.012
organophosphate metabolic processGO:00196371950.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
chromatin organizationGO:00063252070.012
locomotory behaviorGO:00076261760.012
response to extracellular stimulusGO:00099911160.012
gland morphogenesisGO:00226121450.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
salivary gland histolysisGO:0035070880.012
pattern recognition receptor signaling pathwayGO:000222120.012
positive regulation of molecular functionGO:00440931360.012
transmembrane transportGO:00550851390.012
cholesterol homeostasisGO:004263230.012
pigment metabolic processGO:0042440840.012
endomembrane system organizationGO:00102561190.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
sensory perception of chemical stimulusGO:00076061160.011
positive regulation of phosphate metabolic processGO:00459371390.011
aromatic compound catabolic processGO:00194391660.011
protein catabolic processGO:00301631010.011
photoreceptor cell differentiationGO:00465301700.011
cellular response to external stimulusGO:0071496660.011
Fly
regulation of response to biotic stimulusGO:0002831630.011
g protein coupled receptor signaling pathwayGO:00071861360.011
developmental programmed cell deathGO:00106231380.011
adult behaviorGO:00305341370.011
salivary gland developmentGO:00074311620.011
positive regulation of intracellular signal transductionGO:19025331160.011
regulation of programmed cell deathGO:00430671520.011
central nervous system developmentGO:00074172010.011
spermatogenesisGO:00072832000.011
blastoderm segmentationGO:00073501590.011
mrna processingGO:00063971040.011
morphogenesis of an epitheliumGO:00020092760.011
sterol homeostasisGO:005509240.011
axon developmentGO:00615642970.011
nucleotide metabolic processGO:00091171610.011
axon guidanceGO:00074112330.011
negative regulation of transcription dna templatedGO:00458922370.011
negative regulation of rna biosynthetic processGO:19026792400.011
nucleobase containing compound catabolic processGO:00346551650.011
cell motilityGO:00488702510.011
rhythmic processGO:00485111060.011
response to woundingGO:0009611940.011
histolysisGO:00075591020.011
cellular response to uvGO:0034644120.011
wound healingGO:0042060750.011
ras protein signal transductionGO:0007265880.011
anion homeostasisGO:005508130.011
chemosensory behaviorGO:00076351060.011
cellular response to oxygen containing compoundGO:1901701790.011
epidermal growth factor receptor signaling pathwayGO:0007173580.011
chaeta developmentGO:0022416970.011
purine ribonucleotide metabolic processGO:00091501450.011
anterior posterior pattern specificationGO:00099521360.011
negative regulation of cellular component organizationGO:00511291080.011
protein complex assemblyGO:00064612000.011
cellular homeostasisGO:0019725800.011
regulation of apoptotic processGO:00429811300.011
embryonic axis specificationGO:00005781070.011
purine nucleotide metabolic processGO:00061631460.011
multi organism behaviorGO:00517051750.011
regulation of response to external stimulusGO:00321011150.011
defense response to gram positive bacteriumGO:0050830410.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
regulation of nervous system developmentGO:00519602480.011
mesenchymal cell developmentGO:001403110.011
telencephalon developmentGO:002153720.010
tissue morphogenesisGO:00487292970.010
negative regulation of immune responseGO:0050777390.010
camera type eye morphogenesisGO:004859320.010
open tracheal system developmentGO:00074242040.010
gland developmentGO:00487321910.010
actin cytoskeleton organizationGO:00300362060.010
regulation of cell developmentGO:00602842150.010
anterior posterior axis specificationGO:00099481090.010
photoreceptor cell developmentGO:0042461960.010
ribonucleoside metabolic processGO:00091191270.010
positive regulation of defense responseGO:0031349590.010
cellular protein localizationGO:00346131600.010
purine nucleoside metabolic processGO:00422781270.010
glycosyl compound metabolic processGO:19016571270.010
negative regulation of immune system processGO:0002683500.010
mesenchymal cell differentiationGO:004876210.010
dorsal ventral pattern formationGO:00099531330.010
positive regulation of lipid storageGO:001088440.010
enzyme linked receptor protein signaling pathwayGO:00071671790.010
vitamin metabolic processGO:000676620.010
regulation of transcription from rna polymerase ii promoterGO:00063573780.010
chitin based cuticle developmentGO:0040003490.010
regulation of gene expression epigeneticGO:00400291280.010

TotC disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
nervous system diseaseDOID:86300.020
disease of metabolismDOID:001466700.018
cardiovascular system diseaseDOID:128700.014
inherited metabolic disorderDOID:65500.014
acquired metabolic diseaseDOID:006015800.013
artery diseaseDOID:005082800.012
vascular diseaseDOID:17800.012
central nervous system diseaseDOID:33100.012
neurodegenerative diseaseDOID:128900.012
musculoskeletal system diseaseDOID:1700.010