Drosophila melanogaster

41 known processes

TotA (Dmel_CG31509)

Turandot A

(Aliases: totA,Turt,Dmel\CG31509,tot,Tot,Tot-A,CG31509)

TotA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to mercury ionGO:004668930.434
insecticide catabolic processGO:004670110.363
lauric acid metabolic processGO:004825210.325
defense response to other organismGO:00985422250.231
insecticide metabolic processGO:001714320.222
secondary metabolite catabolic processGO:009048710.204
toxin catabolic processGO:000940710.177
response to other organismGO:00517072930.176
xenobiotic catabolic processGO:004217810.170
secondary metabolic processGO:0019748750.138
response to organophosphorusGO:004668320.131
fat soluble vitamin biosynthetic processGO:004236210.125
defense responseGO:00069523000.120
steroid catabolic processGO:000670610.117
response to organic substanceGO:00100332840.116
response to external biotic stimulusGO:00432072930.115
vitamin biosynthetic processGO:000911010.114
vitamin metabolic processGO:000676620.106
catabolic processGO:00090564090.103
response to bacteriumGO:00096171980.101
lipid metabolic processGO:00066291210.098
cellular catabolic processGO:00442483720.095
response to biotic stimulusGO:00096072940.095
defense response to bacteriumGO:00427421780.090
response to insecticideGO:0017085140.083
organonitrogen compound metabolic processGO:19015643180.073
positive regulation of gene expressionGO:00106282900.071
organic hydroxy compound metabolic processGO:1901615830.071
small molecule metabolic processGO:00442813050.068
organonitrogen compound catabolic processGO:19015651280.065
homeostatic processGO:00425921990.060
carboxylic acid metabolic processGO:0019752920.060
single organism behaviorGO:00447083910.059
polyol biosynthetic processGO:004617330.058
organic substance catabolic processGO:19015753080.057
immune system processGO:00023763470.056
oxoacid metabolic processGO:00434361030.056
single organism catabolic processGO:00447122280.056
cellular ketone metabolic processGO:0042180240.056
imaginal disc derived appendage morphogenesisGO:00351143950.055
developmental growthGO:00485892800.055
response to metal ionGO:0010038230.055
anion homeostasisGO:005508130.055
behavioral response to ethanolGO:0048149490.054
growthGO:00400073590.054
cellular response to chemical stimulusGO:00708871990.054
wing disc morphogenesisGO:00074723440.053
ion homeostasisGO:0050801550.053
cellular hormone metabolic processGO:0034754230.052
cellular ion homeostasisGO:0006873390.051
response to oxygen containing compoundGO:19017002000.050
imaginal disc derived appendage developmentGO:00487373990.050
response to abiotic stimulusGO:00096283410.050
multi organism behaviorGO:00517051750.048
response to toxic substanceGO:0009636220.048
nuclear divisionGO:00002803320.047
post embryonic appendage morphogenesisGO:00351203850.046
agingGO:00075681430.046
appendage developmentGO:00487364010.045
regulation of anatomical structure sizeGO:00900661630.045
response to organic cyclic compoundGO:0014070890.044
cellular lipid metabolic processGO:0044255830.043
organic hydroxy compound biosynthetic processGO:1901617210.043
aggressive behaviorGO:0002118630.042
ketone biosynthetic processGO:0042181160.042
organic acid metabolic processGO:00060821030.042
sensory perception of chemical stimulusGO:00076061160.042
steroid biosynthetic processGO:0006694160.041
medium chain fatty acid metabolic processGO:005179110.041
regulation of growthGO:00400082330.039
cellular nitrogen compound catabolic processGO:00442701650.038
imaginal disc derived wing morphogenesisGO:00074763370.038
positive regulation of macromolecule metabolic processGO:00106044050.038
chemical homeostasisGO:0048878920.038
cellular amine metabolic processGO:0044106120.038
response to nitrogen compoundGO:1901698900.038
single organism biosynthetic processGO:00447112060.037
defense response to gram negative bacteriumGO:0050829940.037
protein modification processGO:00362114380.037
hormone metabolic processGO:0042445330.037
organelle fissionGO:00482853400.036
phosphorylationGO:00163102940.036
immune responseGO:00069552460.036
columnar cuboidal epithelial cell developmentGO:00020662490.036
positive regulation of multicellular organismal processGO:00512401430.036
ecdysteroid metabolic processGO:0045455190.036
response to ddtGO:004668050.036
organophosphate metabolic processGO:00196371950.035
vesicle mediated transportGO:00161923810.035
cellular amino acid metabolic processGO:0006520610.034
lipid biosynthetic processGO:0008610460.034
immune response regulating signaling pathwayGO:000276420.034
neurological system processGO:00508773580.034
small molecule biosynthetic processGO:0044283370.033
amine metabolic processGO:0009308120.033
negative regulation of cellular metabolic processGO:00313243820.033
intracellular signal transductionGO:00355563000.031
ethanolamine containing compound metabolic processGO:004243940.031
ecdysteroid biosynthetic processGO:0045456150.031
positive regulation of nitrogen compound metabolic processGO:00511733540.031
cellular homeostasisGO:0019725800.030
appendage morphogenesisGO:00351073970.029
positive regulation of cell communicationGO:00106472500.029
positive regulation of signalingGO:00230562430.029
epithelium migrationGO:00901321480.029
cellular protein modification processGO:00064644380.028
positive regulation of signal transductionGO:00099672230.028
cell proliferationGO:00082832990.027
cell deathGO:00082192790.027
taxisGO:00423303040.027
septate junction assemblyGO:0019991260.026
alcohol metabolic processGO:0006066250.026
cellular macromolecule localizationGO:00707272200.026
regulation of protein metabolic processGO:00512462560.026
columnar cuboidal epithelial cell differentiationGO:00020652560.026
adult behaviorGO:00305341370.026
regionalizationGO:00030024160.026
ras protein signal transductionGO:0007265880.026
oxidation reduction processGO:00551141230.026
ribonucleoside metabolic processGO:00091191270.026
regulation of developmental growthGO:00486381740.026
tissue morphogenesisGO:00487292970.026
response to extracellular stimulusGO:00099911160.026
response to transition metal nanoparticleGO:199026790.025
open tracheal system developmentGO:00074242040.025
negative regulation of cell communicationGO:00106482230.025
regulation of catalytic activityGO:00507901850.025
g protein coupled receptor signaling pathwayGO:00071861360.025
monocarboxylic acid metabolic processGO:0032787290.025
epithelial cell differentiationGO:00308553220.025
sensory perceptionGO:00076001960.025
endocytosisGO:00068973100.025
programmed cell deathGO:00125012570.025
negative regulation of gene expressionGO:00106293870.025
male gamete generationGO:00482322010.024
response to temperature stimulusGO:00092661060.024
negative regulation of signal transductionGO:00099682060.024
positive regulation of response to stimulusGO:00485843230.024
deathGO:00162652840.024
negative regulation of response to stimulusGO:00485852580.023
cellular response to heatGO:0034605240.023
circulatory system processGO:0003013370.023
neuron recognitionGO:00080381010.023
regulation of intracellular signal transductionGO:19025312360.023
establishment of localization in cellGO:00516494020.023
hormone biosynthetic processGO:0042446200.023
epidermis developmentGO:0008544650.023
carbohydrate derivative metabolic processGO:19011352170.023
response to copper ionGO:004668840.023
hormone catabolic processGO:004244730.023
phagocytosisGO:00069092150.023
alcohol biosynthetic processGO:0046165140.023
actin filament based processGO:00300292200.023
response to nutrient levelsGO:00316671140.023
response to oxidative stressGO:0006979860.023
small gtpase mediated signal transductionGO:0007264880.023
regulation of cellular amine metabolic processGO:003323830.023
positive regulation of nucleobase containing compound metabolic processGO:00459353320.023
regulation of cellular ketone metabolic processGO:001056530.023
regulation of hormone levelsGO:0010817400.022
purine nucleoside metabolic processGO:00422781270.022
cellular chemical homeostasisGO:0055082400.022
acetylcholine metabolic processGO:000829120.022
regulation of tube sizeGO:0035150460.022
ovarian follicle cell migrationGO:00072971210.022
regulation of molecular functionGO:00650092170.022
response to inorganic substanceGO:0010035440.022
steroid metabolic processGO:0008202200.022
acetate ester metabolic processGO:190061920.022
purine ribonucleoside metabolic processGO:00461281270.022
regulation of cellular amino acid metabolic processGO:000652100.022
regulation of phosphorus metabolic processGO:00511742100.022
morphogenesis of an epitheliumGO:00020092760.022
cellular response to abiotic stimulusGO:0071214580.021
ameboidal type cell migrationGO:00016671510.021
biological adhesionGO:00226101380.021
neurotransmitter catabolic processGO:004213510.021
regulation of nervous system developmentGO:00519602480.021
innate immune responseGO:00450871440.021
peptide metabolic processGO:0006518800.021
organic cyclic compound catabolic processGO:19013611680.021
eye morphogenesisGO:00485922600.020
purine containing compound metabolic processGO:00725211550.020
female meiosis chromosome segregationGO:0016321330.020
regulation of blood circulationGO:1903522210.020
macromolecule catabolic processGO:00090571610.020
meiotic cell cycleGO:00513211710.020
chemotaxisGO:00069352490.020
phosphatidic acid metabolic processGO:004647310.020
multi multicellular organism processGO:00447061230.020
neuron projection guidanceGO:00974852410.020
regulation of transportGO:00510491810.020
nucleoside phosphate metabolic processGO:00067531620.020
choline metabolic processGO:001969510.020
nucleobase containing compound catabolic processGO:00346551650.019
positive regulation of phosphate metabolic processGO:00459371390.019
negative regulation of protein metabolic processGO:0051248850.019
positive regulation of biosynthetic processGO:00098913160.019
negative regulation of signalingGO:00230572190.019
cell cell junction organizationGO:0045216550.019
response to light stimulusGO:00094161240.019
organic substance transportGO:00717022570.019
localization of cellGO:00516742570.019
sterol metabolic processGO:0016125120.019
regulation of response to stressGO:00801342000.019
cell motilityGO:00488702510.019
cell recognitionGO:00080371020.019
embryonic development via the syncytial blastodermGO:00017001480.019
regulation of mapk cascadeGO:0043408920.019
ion transmembrane transportGO:00342201220.019
response to alcoholGO:0097305950.018
nucleobase containing small molecule metabolic processGO:00550861740.018
regulation of transcription from rna polymerase ii promoterGO:00063573780.018
positive regulation of phosphorus metabolic processGO:00105621390.018
axon guidanceGO:00074112330.018
regulation of phosphate metabolic processGO:00192202100.018
immune effector processGO:0002252980.018
ecdysone metabolic processGO:0008205110.018
neurotransmitter metabolic processGO:004213320.018
chromosome segregationGO:00070591570.018
carbohydrate derivative catabolic processGO:19011361180.018
response to heatGO:0009408630.018
regulation of organelle organizationGO:00330431960.018
regulation of immune system processGO:00026821760.018
regulation of cellular protein metabolic processGO:00322682430.018
tissue migrationGO:00901301550.018
lipid catabolic processGO:0016042210.018
response to radiationGO:00093141550.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
nucleoside metabolic processGO:00091161270.018
actin cytoskeleton organizationGO:00300362060.018
spermatogenesisGO:00072832000.018
cell adhesionGO:00071551360.017
regulation of multicellular organismal developmentGO:20000264140.017
aromatic compound catabolic processGO:00194391660.017
cellular response to dna damage stimulusGO:00069742230.017
positive regulation of macromolecule biosynthetic processGO:00105572830.017
epithelial cell developmentGO:00020642740.017
transcription from rna polymerase ii promoterGO:00063663680.017
cellular protein localizationGO:00346131600.017
cation homeostasisGO:0055080510.017
fatty acid metabolic processGO:0006631200.017
synaptic transmissionGO:00072682880.017
cellular response to biotic stimulusGO:007121640.017
response to ethanolGO:0045471590.016
metal ion transportGO:0030001740.016
immune response activating signal transductionGO:000275720.016
mapk cascadeGO:00001651070.016
exocrine system developmentGO:00352721620.016
tergite morphogenesisGO:000749010.016
nucleoside catabolic processGO:00091641120.016
skin developmentGO:0043588650.016
organelle assemblyGO:00709251980.016
compound eye morphogenesisGO:00017452490.016
regulation of neurogenesisGO:00507671580.016
metal ion homeostasisGO:0055065440.016
meiotic nuclear divisionGO:00071261510.016
tube developmentGO:00352952440.016
pigment metabolic processGO:0042440840.016
antimicrobial humoral responseGO:0019730990.016
protein phosphorylationGO:00064681690.016
organonitrogen compound biosynthetic processGO:19015661170.016
sterol homeostasisGO:005509240.016
cellular response to lipopolysaccharideGO:007122230.016
ecdysone biosynthetic processGO:000669790.015
regulation of cell cycleGO:00517262910.015
positive regulation of molecular functionGO:00440931360.015
lipid localizationGO:0010876540.015
positive regulation of catalytic activityGO:00430851180.015
cuticle developmentGO:0042335860.015
macromolecular complex assemblyGO:00650032560.015
positive regulation of cell motilityGO:200014730.015
spindle organizationGO:00070512530.015
positive regulation of rna metabolic processGO:00512542710.015
regulation of neuron projection developmentGO:0010975690.015
positive regulation of cell migrationGO:003033520.015
response to paraquatGO:190156240.015
digestive tract developmentGO:00485651490.015
central nervous system developmentGO:00074172010.014
regulation of small gtpase mediated signal transductionGO:0051056930.014
mating behaviorGO:00076171060.014
epithelial cell migrationGO:00106311480.014
axon developmentGO:00615642970.014
salivary gland developmentGO:00074311620.014
response to lipopolysaccharideGO:003249640.014
positive regulation of immune system processGO:0002684680.014
cation transportGO:00068121100.014
signal transduction by phosphorylationGO:00230141070.014
protein localizationGO:00081042840.014
negative regulation of cellular protein metabolic processGO:0032269850.014
regulation of catabolic processGO:00098941700.014
choline catabolic processGO:004242610.014
regulation of phosphorylationGO:00423251470.014
terpenoid metabolic processGO:000672170.014
lipopolysaccharide mediated signaling pathwayGO:003166310.014
purine ribonucleoside triphosphate metabolic processGO:00092051190.014
nucleotide metabolic processGO:00091171610.014
positive regulation of intracellular signal transductionGO:19025331160.014
negative regulation of cellular component organizationGO:00511291080.014
body morphogenesisGO:001017120.014
transmembrane transportGO:00550851390.014
embryonic morphogenesisGO:00485982060.014
regulation of apoptotic processGO:00429811300.014
posttranscriptional regulation of gene expressionGO:00106081450.014
proteolysisGO:00065081920.014
cellular response to radiationGO:0071478520.014
response to monosaccharideGO:003428440.013
cellular response to molecule of bacterial originGO:007121930.013
maintenance of locationGO:0051235730.013
multicellular organismal agingGO:00102591400.013
actin filament organizationGO:00070151260.013
glycosyl compound metabolic processGO:19016571270.013
regulation of programmed cell deathGO:00430671520.013
digestive system developmentGO:00551231490.013
regulation of cell differentiationGO:00455953020.013
dna metabolic processGO:00062592270.013
regulation of cell proliferationGO:00421271630.013
transition metal ion homeostasisGO:0055076170.013
cellular response to oxygen containing compoundGO:1901701790.013
triglyceride homeostasisGO:0070328180.013
response to uvGO:0009411240.013
embryo development ending in birth or egg hatchingGO:00097921520.013
regulation of localizationGO:00328792750.013
positive regulation of rna biosynthetic processGO:19026802660.013
sterol biosynthetic processGO:001612690.013
cellular response to oxidative stressGO:0034599280.013
regulation of system processGO:0044057360.013
toxin metabolic processGO:000940420.013
regulation of cellular catabolic processGO:00313291570.013
blood circulationGO:0008015260.013
connective tissue developmentGO:006144830.013
autophagic cell deathGO:0048102830.013
chromosome organizationGO:00512763600.013
respiratory system developmentGO:00605412130.013
matingGO:00076181200.013
compound eye developmentGO:00487493070.013
regulation of ras protein signal transductionGO:0046578930.012
cell migrationGO:00164772380.012
response to woundingGO:0009611940.012
positive regulation of cellular catabolic processGO:0031331950.012
glycosyl compound catabolic processGO:19016581120.012
regulation of cell developmentGO:00602842150.012
heterocycle catabolic processGO:00467001660.012
ion transportGO:00068111450.012
sensory organ morphogenesisGO:00905962600.012
cellular metal ion homeostasisGO:0006875310.012
telencephalon developmentGO:002153720.012
cell maturationGO:00484691440.012
developmental maturationGO:00217001720.012
mitotic nuclear divisionGO:00070672130.012
cellular response to starvationGO:0009267610.012
regulation of cell deathGO:00109411730.012
cellular biogenic amine catabolic processGO:004240210.012
male mating behaviorGO:0060179700.012
cellular cation homeostasisGO:0030003380.012
transition metal ion transportGO:0000041160.012
negative regulation of biosynthetic processGO:00098902770.012
regulation of cell morphogenesisGO:00226041630.012
cellular macromolecule catabolic processGO:00442651360.012
endomembrane system organizationGO:00102561190.012
cellular response to organic substanceGO:00713101320.012
developmental programmed cell deathGO:00106231380.011
response to caffeineGO:0031000120.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
fat soluble vitamin metabolic processGO:000677510.011
positive regulation of cellular protein metabolic processGO:00322701180.011
apoptotic processGO:00069151590.011
mrna metabolic processGO:00160711240.011
rho protein signal transductionGO:0007266140.011
dorsal closureGO:0007391790.011
sensory perception of smellGO:0007608800.011
leg disc developmentGO:0035218920.011
eye developmentGO:00016543230.011
axis specificationGO:00097981670.011
positive regulation of developmental processGO:00510941430.011
dendrite morphogenesisGO:00488131990.011
gland developmentGO:00487321910.011
response to endogenous stimulusGO:00097191190.011
negative regulation of developmental processGO:00510932010.011
chitin based cuticle developmentGO:0040003490.011
wound healingGO:0042060750.011
glycerolipid metabolic processGO:0046486340.011
kidney developmentGO:000182230.011
regulation of immune responseGO:00507761180.011
establishment of protein localizationGO:00451841630.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
regulation of cellular component biogenesisGO:00440872010.011
positive regulation of transcription dna templatedGO:00458932660.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
cation transmembrane transportGO:0098655880.011
ovarian follicle cell developmentGO:00307072480.011
ribose phosphate metabolic processGO:00196931450.011
meiotic cell cycle processGO:19030461320.011
response to hexoseGO:000974630.011
neuropeptide signaling pathwayGO:0007218450.011
ribonucleotide metabolic processGO:00092591450.011
response to purine containing compoundGO:0014074120.011
cell junction assemblyGO:0034329420.011
ribonucleoside catabolic processGO:00424541120.011
purine ribonucleotide metabolic processGO:00091501450.011
determination of adult lifespanGO:00083401370.010
cellular component assembly involved in morphogenesisGO:00109271510.010
mitotic spindle organizationGO:00070522200.010
dendrite developmentGO:00163582040.010
gland morphogenesisGO:00226121450.010
drinking behaviorGO:004275620.010
negative regulation of macromolecule biosynthetic processGO:00105582700.010
purine nucleoside catabolic processGO:00061521120.010
negative regulation of rna metabolic processGO:00512532510.010
oxidoreduction coenzyme metabolic processGO:000673320.010
camera type eye developmentGO:004301040.010
positive regulation of cellular component organizationGO:00511301560.010
purine nucleotide metabolic processGO:00061631460.010
organic hydroxy compound catabolic processGO:190161640.010
synaptic target recognitionGO:0008039450.010
segmentationGO:00352822070.010
phosphatidylinositol mediated signalingGO:004801540.010
ribonucleoside triphosphate metabolic processGO:00091991190.010
amide biosynthetic processGO:0043604420.010
regulation of response to biotic stimulusGO:0002831630.010
regulation of vesicle mediated transportGO:0060627590.010
protein complex biogenesisGO:00702712010.010
purine containing compound catabolic processGO:00725231120.010

TotA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
essential hypertensionDOID:1082500.179
artery diseaseDOID:005082800.179
hypertensionDOID:1076300.179
disease of anatomical entityDOID:700.179
vascular diseaseDOID:17800.179
cardiovascular system diseaseDOID:128700.179
disease of metabolismDOID:001466700.019
nervous system diseaseDOID:86300.015
acquired metabolic diseaseDOID:006015800.011
inherited metabolic disorderDOID:65500.011
musculoskeletal system diseaseDOID:1700.010