Drosophila melanogaster

126 known processes

lea (Dmel_CG5481)

leak

(Aliases: Robo 2,CT17326,Robo2,Dmel\CG5481,clone 1.75,Robo-2,ROBO2,D-robo2,CG14347,D-Robo2,robo-2,anon-EST:Liang-1.75,dRobo-2,CG14348,robo2,CG5481,CG5574)

lea biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
motor neuron axon guidanceGO:0008045581.000
Fly
axon choice point recognitionGO:0016198260.996
Zebrafish Mouse Rat Fly
ventral cord developmentGO:0007419160.996
salivary gland boundary specificationGO:000743280.994
axon developmentGO:00615642970.991
dorsal ventral axon guidanceGO:003356320.991
Worm
axon midline choice point recognitionGO:0016199260.988
Zebrafish Mouse Rat Fly
regulation of cell differentiationGO:00455953020.988
Human Zebrafish Rat Fly
regulation of dendrite morphogenesisGO:0048814280.984
Rat
central nervous system developmentGO:00074172010.980
dendrite guidanceGO:0070983210.971
Fly
growthGO:00400073590.967
Zebrafish Mouse
neuron projection guidanceGO:00974852410.958
axon guidanceGO:00074112330.955
neuron recognitionGO:00080381010.944
negative regulation of growthGO:0045926840.929
Zebrafish
substrate dependent cell migrationGO:000692930.925
Human
central nervous system projection neuron axonogenesisGO:002195260.925
Zebrafish
central complex developmentGO:004803690.917
retinal ganglion cell axon guidanceGO:0031290120.917
Zebrafish Mouse
regulation of axon extension involved in axon guidanceGO:004884140.915
Zebrafish
dendrite developmentGO:00163582040.910
Rat Fly
cardioblast cell fate commitmentGO:0042684140.906
axon extension involved in axon guidanceGO:0048846100.906
Zebrafish
regulation of axon guidanceGO:1902667100.901
Zebrafish
axonogenesisGO:00074092900.899
regionalizationGO:00030024160.891
regulation of epithelial cell migrationGO:0010632120.884
regulation of cell developmentGO:00602842150.880
Human Zebrafish Rat Fly
regulation of apoptotic processGO:00429811300.860
Human
cell recognitionGO:00080371020.844
regulation of cell deathGO:00109411730.837
Human
positive regulation of axonogenesisGO:005077220.823
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.822
tube developmentGO:00352952440.818
brain developmentGO:00074201200.811
respiratory system developmentGO:00605412130.808
negative regulation of transcription dna templatedGO:00458922370.789
regulation of multicellular organismal developmentGO:20000264140.788
axon extensionGO:0048675320.783
Zebrafish
negative regulation of developmental growthGO:0048640640.782
Zebrafish
circulatory system developmentGO:0072359820.768
tissue migrationGO:00901301550.754
positive regulation of cellular biosynthetic processGO:00313283160.751
positive regulation of nitrogen compound metabolic processGO:00511733540.750
ameboidal type cell migrationGO:00016671510.738
apoptotic processGO:00069151590.729
Human
glial cell migrationGO:0008347310.726
epithelial cell migration open tracheal systemGO:0007427320.719
negative regulation of macromolecule biosynthetic processGO:00105582700.711
regulation of neuron projection developmentGO:0010975690.707
Human Zebrafish Rat Fly
cardiac cell fate commitmentGO:0060911170.697
regulation of response to external stimulusGO:00321011150.692
Human Zebrafish
cardioblast differentiationGO:0010002200.674
open tracheal system developmentGO:00074242040.671
salivary gland developmentGO:00074311620.666
neuroblast fate commitmentGO:0014017190.657
kidney epithelium developmentGO:007207330.650
Human Mouse
embryonic organ developmentGO:0048568500.638
developmental cell growthGO:0048588520.635
Zebrafish
heart developmentGO:0007507820.635
telencephalon developmentGO:002153720.621
Human Mouse
cell projection assemblyGO:0030031940.612
Zebrafish
positive regulation of signalingGO:00230562430.606
Zebrafish
cardiocyte differentiationGO:0035051290.601
regulation of epithelial cell migration open tracheal systemGO:2000274110.599
mushroom body developmentGO:0016319700.590
heart morphogenesisGO:0003007320.587
positive regulation of macromolecule metabolic processGO:00106044050.586
Human
convergent extensionGO:006002620.585
Zebrafish
developmental growth involved in morphogenesisGO:0060560650.582
Zebrafish Mouse
regulation of developmental growthGO:00486381740.574
Zebrafish
olfactory bulb axon guidanceGO:007167830.562
localization of cellGO:00516742570.562
regulation of programmed cell deathGO:00430671520.560
Human
renal system developmentGO:0072001720.558
Human Mouse
head developmentGO:00603221350.553
cardiovascular system developmentGO:0072358820.546
negative regulation of signalingGO:00230572190.545
Human
cell motilityGO:00488702510.541
negative regulation of axon extensionGO:003051730.540
Zebrafish
gonad developmentGO:0008406500.516
muscle structure developmentGO:00610612240.515
programmed cell deathGO:00125012570.513
Human
formation of anatomical boundaryGO:0048859370.496
organ formationGO:0048645390.496
stem cell differentiationGO:00488631170.493
internal protein amino acid acetylationGO:0006475380.492
regulation of axonogenesisGO:0050770320.491
Human Zebrafish
regulation of cell morphogenesisGO:00226041630.482
Human Zebrafish Rat
filopodium assemblyGO:0046847330.476
Zebrafish
deathGO:00162652840.473
Human
forebrain developmentGO:003090020.463
Human Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.459
Human
catabolic processGO:00090564090.456
anterior posterior pattern specificationGO:00099521360.456
negative regulation of gene expressionGO:00106293870.455
positive regulation of cell differentiationGO:0045597640.452
Human
embryonic development via the syncytial blastodermGO:00017001480.449
positive regulation of gene expressionGO:00106282900.444
synapse assemblyGO:00074161430.436
Zebrafish
outflow tract morphogenesisGO:000315140.432
cardioblast cell fate specificationGO:004268590.425
regulation of cell growthGO:0001558430.425
Zebrafish
neuron migrationGO:000176450.417
negative regulation of cellular biosynthetic processGO:00313272770.412
positive regulation of neurogenesisGO:0050769410.412
Human
intracellular signal transductionGO:00355563000.409
Zebrafish
positive regulation of cell projection organizationGO:0031346290.405
Human
negative regulation of nucleic acid templated transcriptionGO:19035072400.405
regulation of cellular component biogenesisGO:00440872010.403
Zebrafish
segmentationGO:00352822070.401
heart formationGO:006091460.401
Zebrafish
muscle organ developmentGO:00075171270.397
activation of cysteine type endopeptidase activityGO:0097202170.396
Human
negative regulation of cell communicationGO:00106482230.394
Human
epithelial tube morphogenesisGO:0060562880.392
Mouse
dendrite morphogenesisGO:00488131990.390
Rat Fly
positive regulation of rna biosynthetic processGO:19026802660.386
reproductive system developmentGO:0061458740.385
positive regulation of multicellular organismal processGO:00512401430.385
Human
morphogenesis of a branching epitheliumGO:0061138450.381
response to endogenous stimulusGO:00097191190.378
Human
regulation of synapse assemblyGO:0051963940.375
Zebrafish
positive regulation of transcription dna templatedGO:00458932660.375
positive regulation of nucleobase containing compound metabolic processGO:00459353320.364
cell fate specificationGO:0001708710.363
regulation of small gtpase mediated signal transductionGO:0051056930.353
Zebrafish
regulation of nervous system developmentGO:00519602480.351
Human Zebrafish Rat Fly
regulation of cell proliferationGO:00421271630.350
Human Mouse
exocrine system developmentGO:00352721620.348
cell migrationGO:00164772380.342
positive regulation of cysteine type endopeptidase activityGO:2001056240.342
Human
small gtpase mediated signal transductionGO:0007264880.340
Zebrafish
regulation of intracellular signal transductionGO:19025312360.337
Zebrafish
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.334
regulation of cell projection organizationGO:0031344920.334
Human Zebrafish Rat Fly
synapse organizationGO:00508081960.333
Zebrafish
sex differentiationGO:0007548810.331
positive regulation of nervous system developmentGO:0051962690.328
Human
lamellipodium organizationGO:0097581210.325
Zebrafish
cardiac cell fate specificationGO:0060912100.324
regulation of photoreceptor cell axon guidanceGO:200028950.317
startle responseGO:0001964160.314
Fly
gastrulationGO:0007369700.312
negative regulation of developmental processGO:00510932010.302
Human Zebrafish
regulation of localizationGO:00328792750.298
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.294
regulation of cysteine type endopeptidase activityGO:2000116270.294
Human
negative regulation of biosynthetic processGO:00098902770.291
central nervous system neuron differentiationGO:002195380.286
Human Zebrafish Mouse
regulation of cell sizeGO:0008361630.282
Zebrafish
chemotaxisGO:00069352490.277
brain morphogenesisGO:0048854160.274
Fly
positive regulation of molecular functionGO:00440931360.274
Human
formation of organ boundaryGO:0010160300.272
developmental growthGO:00485892800.269
Zebrafish Mouse
tissue morphogenesisGO:00487292970.263
Zebrafish Mouse
cellular response to chemical stimulusGO:00708871990.263
Human Mouse
response to organic substanceGO:00100332840.251
Human
stem cell fate commitmentGO:0048865250.250
taxisGO:00423303040.249
reproductive structure developmentGO:0048608740.246
positive regulation of cell motilityGO:200014730.242
regulation of synapse organizationGO:00508071100.234
Zebrafish
cell proliferationGO:00082832990.228
Human Mouse
regulation of growthGO:00400082330.228
Zebrafish
regulation of cell morphogenesis involved in differentiationGO:0010769610.226
Human Zebrafish Rat
regulation of organelle organizationGO:00330431960.217
negative regulation of nucleobase containing compound metabolic processGO:00459342610.215
neuroblast developmentGO:0014019130.213
regulation of transcription from rna polymerase ii promoterGO:00063573780.212
roundabout signaling pathwayGO:003538540.211
Human Fly
negative regulation of apoptotic processGO:0043066630.209
peptidyl lysine acetylationGO:0018394390.206
neuron fate specificationGO:0048665120.205
negative regulation of nitrogen compound metabolic processGO:00511722650.203
ras protein signal transductionGO:0007265880.199
Zebrafish
neuroblast differentiationGO:0014016290.193
negative regulation of response to external stimulusGO:0032102220.191
Human Zebrafish
chromosome organizationGO:00512763600.190
appendage developmentGO:00487364010.186
regulation of neuron differentiationGO:00456641030.185
Human Zebrafish Rat Fly
positive regulation of axon guidanceGO:190266910.183
embryo development ending in birth or egg hatchingGO:00097921520.181
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.175
Human
neuroblast fate specificationGO:001401820.173
embryonic heart tube developmentGO:0035050220.167
negative regulation of synapse assemblyGO:0051964390.166
Zebrafish
positive regulation of cell adhesionGO:0045785100.163
cell maturationGO:00484691440.162
negative regulation of rna biosynthetic processGO:19026792400.158
malpighian tubule developmentGO:0072002640.156
transcription from rna polymerase ii promoterGO:00063663680.153
positive regulation of intracellular signal transductionGO:19025331160.148
Zebrafish
regulation of anatomical structure morphogenesisGO:00226032420.145
Human Zebrafish Rat
imaginal disc derived appendage developmentGO:00487373990.145
germ cell migrationGO:0008354430.141
anterior posterior axis specificationGO:00099481090.141
positive regulation of developmental processGO:00510941430.140
Human
leg disc developmentGO:0035218920.140
regulation of cell substrate adhesionGO:001081020.139
Zebrafish
positive regulation of macromolecule biosynthetic processGO:00105572830.136
positive regulation of proteolysisGO:0045862520.135
Human
neuron projection extension involved in neuron projection guidanceGO:1902284100.135
Zebrafish
negative regulation of cell deathGO:0060548810.134
proteolysisGO:00065081920.133
Human
neuron projection extensionGO:1990138320.132
Zebrafish
malpighian tubule morphogenesisGO:0007443440.131
cell fate determinationGO:0001709910.128
epidermis developmentGO:0008544650.127
eye photoreceptor cell fate commitmentGO:0042706370.126
cellular ketone metabolic processGO:0042180240.124
regulation of synapse structure and activityGO:00508031280.123
Zebrafish
negative regulation of chemotaxisGO:005092210.121
Human Zebrafish
body morphogenesisGO:001017120.121
urogenital system developmentGO:0001655720.120
Human Mouse
regulation of protein metabolic processGO:00512462560.120
Human
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.118
Human
epithelial cell migrationGO:00106311480.117
regulation of hydrolase activityGO:0051336970.117
Human
negative regulation of response to stimulusGO:00485852580.116
Human Zebrafish
dendrite self avoidanceGO:007059380.116
cardiac cell fate determinationGO:006091330.116
positive regulation of nucleic acid templated transcriptionGO:19035082660.115
regulation of cell migrationGO:0030334220.115
determination of ventral identityGO:004826410.114
Zebrafish
spinal cord developmentGO:002151010.112
Rat
positive regulation of hydrolase activityGO:0051345780.111
Human
chromatin organizationGO:00063252070.110
positive regulation of axon extensionGO:004577320.109
embryonic pattern specificationGO:00098801740.109
leg disc proximal distal pattern formationGO:000747990.108
positive regulation of cellular component organizationGO:00511301560.107
Human
regulation of locomotionGO:0040012420.107
mesodermal cell migrationGO:000807870.107
morphogenesis of an epitheliumGO:00020092760.106
Zebrafish Mouse
central nervous system neuron axonogenesisGO:002195570.103
Zebrafish
positive regulation of cell cell adhesionGO:002240990.103
determination of dorsal ventral asymmetryGO:004826230.101
Zebrafish
positive regulation of cell migrationGO:003033520.101
chromatin modificationGO:00165681470.101
terminal region determinationGO:0007362250.101
blastoderm segmentationGO:00073501590.100
photoreceptor cell axon guidanceGO:0072499230.098
Fly
negative regulation of rna metabolic processGO:00512532510.097
anterior commissure morphogenesisGO:002196020.096
epithelium migrationGO:00901321480.096
actin polymerization or depolymerizationGO:0008154310.093
organic substance catabolic processGO:19015753080.092
imaginal disc derived appendage morphogenesisGO:00351143950.091
positive regulation of cell deathGO:0010942690.090
Human
axonal defasciculationGO:0007414120.090
gland morphogenesisGO:00226121450.089
Mouse
positive regulation of ras protein signal transductionGO:0046579430.089
Zebrafish
positive regulation of rna metabolic processGO:00512542710.089
phosphatidylinositol 3 kinase signalingGO:001406540.088
camera type eye developmentGO:004301040.087
positive regulation of cell developmentGO:0010720610.087
Human
regulation of photoreceptor cell differentiationGO:0046532340.084
digestive tract developmentGO:00485651490.084
humoral immune responseGO:00069591170.083
response to biotic stimulusGO:00096072940.082
digestive system developmentGO:00551231490.080
cell migration involved in gastrulationGO:004207490.078
single organism cell adhesionGO:0098602470.078
camera type eye morphogenesisGO:004859320.077
gland developmentGO:00487321910.077
embryonic morphogenesisGO:00485982060.076
negative regulation of multicellular organismal processGO:00512411420.076
Human Zebrafish
sensory organ morphogenesisGO:00905962600.076
regulation of ras protein signal transductionGO:0046578930.075
Zebrafish
kidney developmentGO:000182230.074
Human Mouse
endocytosisGO:00068973100.073
purine ribonucleotide catabolic processGO:00091541090.072
phosphatidylinositol mediated signalingGO:004801540.072
response to other organismGO:00517072930.072
negative regulation of cell differentiationGO:00455961430.071
Zebrafish
negative regulation of nervous system developmentGO:0051961920.071
Zebrafish
regulation of extent of cell growthGO:006138780.071
Zebrafish
response to woundingGO:0009611940.070
cell deathGO:00082192790.070
Human
small molecule metabolic processGO:00442813050.070
regulation of proteolysisGO:0030162870.070
Human
signal transduction in response to dna damageGO:004277030.069
enzyme linked receptor protein signaling pathwayGO:00071671790.068
regulation of neurogenesisGO:00507671580.067
Human Zebrafish Rat Fly
digestive tract morphogenesisGO:00485461270.067
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.066
Human
positive regulation of cell communicationGO:00106472500.065
Zebrafish
synaptic target recognitionGO:0008039450.065
negative regulation of neurogenesisGO:0050768530.064
Zebrafish
regulation of catalytic activityGO:00507901850.064
Human
appendage morphogenesisGO:00351073970.062
cardioblast cell fate determinationGO:000751030.062
development of primary sexual characteristicsGO:0045137500.062
biological adhesionGO:00226101380.061
regulation of anatomical structure sizeGO:00900661630.060
Zebrafish
skin developmentGO:0043588650.060
positive regulation of response to stimulusGO:00485843230.059
Zebrafish
response to organic cyclic compoundGO:0014070890.059
oocyte anterior posterior axis specificationGO:0007314720.058
single organismal cell cell adhesionGO:0016337450.057
nucleoside phosphate catabolic processGO:19012921100.056
photoreceptor cell fate commitmentGO:0046552410.056
cell divisionGO:00513012480.055
oocyte axis specificationGO:00073091080.055
gliogenesisGO:0042063800.055
response to alcoholGO:0097305950.054
regulation of embryonic developmentGO:0045995680.054
organonitrogen compound metabolic processGO:19015643180.054
salivary gland morphogenesisGO:00074351450.054
regulation of circadian rhythmGO:0042752490.053
Fly
post embryonic appendage morphogenesisGO:00351203850.053
wound healingGO:0042060750.053
regulation of phosphatase activityGO:001092130.053
positive regulation of cellular protein metabolic processGO:00322701180.052
Human
regulation of endocytosisGO:0030100370.051
regulation of rac protein signal transductionGO:003502030.051
Zebrafish
cellular catabolic processGO:00442483720.051
columnar cuboidal epithelial cell developmentGO:00020662490.050
nucleotide catabolic processGO:00091661090.049
anatomical structure homeostasisGO:0060249970.049
Fly
neuron deathGO:0070997270.049
positive regulation of endopeptidase activityGO:0010950260.048
Human
zymogen activationGO:0031638200.048
Human
axonal fasciculationGO:0007413120.048
Zebrafish
regulation of epithelial cell differentiationGO:003085640.048
cellular nitrogen compound catabolic processGO:00442701650.047
positive regulation of signal transductionGO:00099672230.047
Zebrafish
negative regulation of cellular metabolic processGO:00313243820.047
cellular homeostasisGO:0019725800.047
Fly
negative regulation of cellular component organizationGO:00511291080.047
Zebrafish
anterior posterior axis specification embryoGO:00085951030.047
cell growthGO:00160491080.047
Zebrafish
regulation of protein acetylationGO:190198370.046
tripartite regional subdivisionGO:00073511030.046
single organism biosynthetic processGO:00447112060.046
branching involved in open tracheal system developmentGO:0060446450.046
regulation of cellular component movementGO:0051270420.045
positive regulation of peptidase activityGO:0010952290.045
Human
positive regulation of programmed cell deathGO:0043068620.045
Human
mesodermal cell fate commitmentGO:000171070.045
protein catabolic processGO:00301631010.045
response to external biotic stimulusGO:00432072930.045
negative regulation of rho protein signal transductionGO:003502410.045
cell matrix adhesionGO:000716060.044
Zebrafish
regulation of cell motilityGO:2000145230.044
eye photoreceptor cell differentiationGO:00017541450.044
gonad morphogenesisGO:003526270.044
spiracle morphogenesis open tracheal systemGO:0035277220.044
organic cyclic compound catabolic processGO:19013611680.043
ocellus developmentGO:000805640.043
peripheral nervous system developmentGO:0007422520.043
cell substrate adhesionGO:0031589100.042
Zebrafish
mesoderm developmentGO:0007498780.042
dorsal ventral pattern formationGO:00099531330.042
Zebrafish
formation of primary germ layerGO:0001704240.042
morphogenesis of embryonic epitheliumGO:0016331940.041
protein modification processGO:00362114380.040
brain segmentationGO:003528450.040
positive regulation of protein metabolic processGO:00512471280.040
Human
embryonic axis specificationGO:00005781070.040
embryonic hemopoiesisGO:0035162260.040
positive regulation of locomotionGO:004001780.040
neuron fate commitmentGO:0048663500.039
central nervous system segmentationGO:003528350.039
dorsal closureGO:0007391790.039
regulation of lamellipodium assemblyGO:0010591150.039
epithelial cell differentiationGO:00308553220.039
regulation of chemotaxisGO:0050920120.038
Human Zebrafish
skeletal muscle organ developmentGO:0060538480.037
glial cell differentiationGO:0010001350.037
mesoderm formationGO:0001707210.037
response to ethanolGO:0045471590.035
gonadal mesoderm developmentGO:000750680.035
regulation of molecular functionGO:00650092170.035
Human
positive regulation of catabolic processGO:00098961050.034
ectodermal placode developmentGO:007169640.034
purine nucleoside triphosphate catabolic processGO:00091461080.034
positive regulation of apoptotic processGO:0043065470.033
Human
branching morphogenesis of an epithelial tubeGO:0048754450.033
positive regulation of neuron projection developmentGO:0010976140.033
Human
regulation of axon extensionGO:003051680.033
Zebrafish
extrinsic apoptotic signaling pathwayGO:009719110.033
inositol lipid mediated signalingGO:004801740.033
nephron tubule morphogenesisGO:007207830.032
ribonucleotide catabolic processGO:00092611090.032
covalent chromatin modificationGO:00165691060.032
pole plasm oskar mrna localizationGO:0045451460.031
hindgut developmentGO:0061525580.031
eye developmentGO:00016543230.031
actin filament bundle organizationGO:0061572280.031
positive regulation of cellular component biogenesisGO:0044089800.030
pharynx developmentGO:006046510.030
regulation of cellular component sizeGO:0032535980.030
Zebrafish
cellular response to endogenous stimulusGO:0071495800.029
Human
neuron apoptotic processGO:0051402170.029
internal peptidyl lysine acetylationGO:0018393380.029
positive regulation of biosynthetic processGO:00098913160.029
vesicle mediated transportGO:00161923810.028
actin filament polymerizationGO:0030041270.028
antimicrobial humoral responseGO:0019730990.028
mesoderm morphogenesisGO:0048332220.028
developmental maturationGO:00217001720.028
central nervous system neuron developmentGO:002195480.028
Human Zebrafish Mouse
regulation of neuron deathGO:1901214260.027
apoptotic signaling pathwayGO:0097190270.027
stem cell fate specificationGO:004886620.027
regulation of chromatin modificationGO:1903308280.027
regulation of neuron apoptotic processGO:0043523160.026
negative regulation of programmed cell deathGO:0043069720.026
positive regulation of neuron differentiationGO:0045666260.025
Human
neuroblast divisionGO:0055057350.025
single organism catabolic processGO:00447122280.025
regulation of cell cycleGO:00517262910.025
negative regulation of phosphatase activityGO:001092330.025
neuroepithelial cell differentiationGO:006056360.024
regulation of cellular amine metabolic processGO:003323830.024
photoreceptor cell differentiationGO:00465301700.024
garland nephrocyte differentiationGO:006132130.024
positive regulation of cell substrate adhesionGO:001081110.024
Zebrafish
protein acylationGO:0043543420.023
negative regulation of cell developmentGO:0010721620.023
Zebrafish
cortical actin cytoskeleton organizationGO:0030866240.023
cell adhesionGO:00071551360.023
amnioserosa maintenanceGO:004666550.023
immune effector processGO:0002252980.023
tube morphogenesisGO:00352391910.023
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092051190.022
regulation of stem cell proliferationGO:0072091400.022
hindbrain developmentGO:003090220.022
synaptic growth at neuromuscular junctionGO:00511241190.022
embryonic organ morphogenesisGO:004856250.022
negative regulation of signal transductionGO:00099682060.022
Human
positive regulation of developmental growthGO:0048639620.022
cellular protein modification processGO:00064644380.021
macromolecular complex assemblyGO:00650032560.021
cellular response to fibroblast growth factor stimulusGO:0044344100.021
retina morphogenesis in camera type eyeGO:006004220.021
cellular response to hormone stimulusGO:0032870440.021
Human
compound eye morphogenesisGO:00017452490.021
regulation of cellular ketone metabolic processGO:001056530.021
stem cell divisionGO:0017145690.021
lamellipodium assemblyGO:0030032210.020
Zebrafish
protein processingGO:0016485680.020
Human
positive regulation of cellular catabolic processGO:0031331950.020
phosphorylationGO:00163102940.020
nucleoside metabolic processGO:00091161270.020
immune system processGO:00023763470.020
collateral sproutingGO:004866830.020
positive regulation of rho gtpase activityGO:0032321190.020
apoptotic process involved in morphogenesisGO:006056130.020
regulation of cellular protein metabolic processGO:00322682430.019
Human
locomotory behaviorGO:00076261760.019
Fly
nephron epithelium developmentGO:007200930.019
regulation of response to woundingGO:1903034190.019
regulation of rho protein signal transductionGO:0035023200.019
epidermal cell differentiationGO:0009913510.019
immune responseGO:00069552460.019
macromolecule catabolic processGO:00090571610.019
response to organonitrogen compoundGO:0010243750.019
regulation of response to stressGO:00801342000.019
negative regulation of cell projection organizationGO:0031345130.019
Zebrafish
regulation of behaviorGO:0050795750.019
Human Zebrafish
actin cytoskeleton organizationGO:00300362060.019
regulation of dendrite developmentGO:0050773370.019
Rat Fly
regulation of mitotic cell cycleGO:00073461900.019
hindgut morphogenesisGO:0007442580.018
positive regulation of gtpase activityGO:0043547430.018
antimicrobial peptide productionGO:0002775460.018
negative regulation of cell proliferationGO:0008285690.018
Human Mouse
positive regulation of phosphate metabolic processGO:00459371390.018
nucleoside triphosphate catabolic processGO:00091431080.018
regulation of histone modificationGO:0031056200.018
dna conformation changeGO:00711031050.018
response to lipidGO:0033993380.018
ribonucleoside triphosphate catabolic processGO:00092031080.018
embryonic epithelial tube formationGO:000183860.017
cellular amino acid metabolic processGO:0006520610.017
negative regulation of intracellular signal transductionGO:1902532570.017
histone modificationGO:00165701060.017
mesenchymal cell developmentGO:001403110.017
parallel actin filament bundle assemblyGO:003004620.017
nucleobase containing compound catabolic processGO:00346551650.017
induction of programmed cell death by hormonesGO:0035081120.017
positive chemotaxisGO:005091840.017
Mouse
leg disc morphogenesisGO:0007478800.017

lea disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.216
Human
nervous system diseaseDOID:86300.045
disease of cellular proliferationDOID:1456600.033
cancerDOID:16200.033
cardiovascular system diseaseDOID:128700.024
heart diseaseDOID:11400.024
congenital heart diseaseDOID:168200.024
urinary system diseaseDOID:1800.023
Human
sensory system diseaseDOID:005015500.023
eye and adnexa diseaseDOID:149200.023
eye diseaseDOID:561400.019