Drosophila melanogaster

104 known processes

Ubp64E (Dmel_CG5486)

Ubiquitin-specific protease 64E

(Aliases: E(var)3-64E,Dmel\CG5486,UBP,D-Ubp-64E,E-var(3)64E,E(var)1,ubp64E,BcDNA:LD12764,ubp64,D-UBP-64E,Ubp64,CG5486)

Ubp64E biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of gene expressionGO:00106293870.421
protein modification by small protein conjugation or removalGO:00706471060.175
regulation of gene expression epigeneticGO:00400291280.132
protein ubiquitinationGO:0016567700.121
spermatogenesisGO:00072832000.114
intracellular signal transductionGO:00355563000.108
Mouse
cellular macromolecule localizationGO:00707272200.098
regulation of response to stressGO:00801342000.096
Mouse
protein modification processGO:00362114380.086
cellular protein modification processGO:00064644380.086
imaginal disc derived appendage developmentGO:00487373990.072
response to other organismGO:00517072930.069
modification dependent macromolecule catabolic processGO:0043632790.066
negative regulation of rna biosynthetic processGO:19026792400.064
regulation of transcription from rna polymerase ii promoterGO:00063573780.064
appendage morphogenesisGO:00351073970.062
muscle structure developmentGO:00610612240.060
negative regulation of macromolecule biosynthetic processGO:00105582700.059
regulation of organelle organizationGO:00330431960.059
regulation of multicellular organismal developmentGO:20000264140.059
cellular macromolecule catabolic processGO:00442651360.058
chromosome organizationGO:00512763600.057
response to biotic stimulusGO:00096072940.057
positive regulation of nitrogen compound metabolic processGO:00511733540.054
response to bacteriumGO:00096171980.053
regulation of cell proliferationGO:00421271630.052
single organism intracellular transportGO:19025822070.050
nuclear divisionGO:00002803320.047
transcription from rna polymerase ii promoterGO:00063663680.046
regulation of cell differentiationGO:00455953020.046
mitotic spindle organizationGO:00070522200.046
response to external biotic stimulusGO:00432072930.046
immune system processGO:00023763470.044
defense response to bacteriumGO:00427421780.042
antimicrobial humoral responseGO:0019730990.042
humoral immune responseGO:00069591170.042
intracellular transportGO:00469072280.041
protein localizationGO:00081042840.041
columnar cuboidal epithelial cell differentiationGO:00020652560.040
positive regulation of nucleic acid templated transcriptionGO:19035082660.040
appendage developmentGO:00487364010.039
imaginal disc derived appendage morphogenesisGO:00351143950.038
modification dependent protein catabolic processGO:0019941780.037
cell cell signaling involved in cell fate commitmentGO:00451682100.037
negative regulation of immune system processGO:0002683500.036
lateral inhibitionGO:00463312060.036
cellular catabolic processGO:00442483720.036
cellular macromolecular complex assemblyGO:00346221530.036
macromolecule catabolic processGO:00090571610.035
programmed cell deathGO:00125012570.035
Human Mouse
cell proliferationGO:00082832990.035
pigment metabolic processGO:0042440840.035
regulation of cellular component biogenesisGO:00440872010.035
positive regulation of nucleobase containing compound metabolic processGO:00459353320.035
regulation of cellular protein metabolic processGO:00322682430.035
Human
negative regulation of transcription dna templatedGO:00458922370.034
mrna metabolic processGO:00160711240.034
single organism cellular localizationGO:19025801800.034
positive regulation of signal transductionGO:00099672230.034
catabolic processGO:00090564090.034
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.034
organic substance transportGO:00717022570.033
regulation of cell developmentGO:00602842150.033
immune responseGO:00069552460.031
ubiquitin dependent protein catabolic processGO:0006511780.031
deathGO:00162652840.031
Human Mouse
cell deathGO:00082192790.030
Human Mouse
negative regulation of biosynthetic processGO:00098902770.030
protein modification by small protein conjugationGO:0032446790.030
cytoplasmic transportGO:00164821300.029
positive regulation of response to stimulusGO:00485843230.029
regulation of multi organism processGO:00439001310.029
posttranscriptional gene silencingGO:0016441460.028
imaginal disc derived wing morphogenesisGO:00074763370.028
spermatid differentiationGO:00485151140.028
gene silencing by rnaGO:0031047570.028
dendrite developmentGO:00163582040.027
male gamete generationGO:00482322010.027
positive regulation of macromolecule biosynthetic processGO:00105572830.027
regulation of notch signaling pathwayGO:00085931000.027
vesicle mediated transportGO:00161923810.027
negative regulation of multicellular organismal processGO:00512411420.026
negative regulation of nervous system developmentGO:0051961920.026
negative regulation of nucleobase containing compound metabolic processGO:00459342610.026
organic substance catabolic processGO:19015753080.026
protein complex assemblyGO:00064612000.025
macromolecular complex assemblyGO:00650032560.025
aromatic compound catabolic processGO:00194391660.025
regulation of immune system processGO:00026821760.025
negative regulation of protein metabolic processGO:0051248850.025
Human
cellular protein catabolic processGO:0044257830.025
negative regulation of cell proliferationGO:0008285690.025
regulation of cellular response to stressGO:0080135890.025
Mouse
positive regulation of cellular biosynthetic processGO:00313283160.025
positive regulation of intracellular signal transductionGO:19025331160.024
posttranscriptional regulation of gene expressionGO:00106081450.024
cellular protein localizationGO:00346131600.024
negative regulation of signal transductionGO:00099682060.023
Mouse
negative regulation of cellular biosynthetic processGO:00313272770.023
protein depolymerizationGO:0051261310.023
small gtpase mediated signal transductionGO:0007264880.023
establishment of protein localizationGO:00451841630.023
negative regulation of cellular protein metabolic processGO:0032269850.023
Human
chromatin organizationGO:00063252070.023
regionalizationGO:00030024160.022
spermatid developmentGO:0007286980.022
regulation of cellular catabolic processGO:00313291570.022
neurological system processGO:00508773580.022
positive regulation of rna metabolic processGO:00512542710.021
establishment of localization in cellGO:00516494020.021
translationGO:0006412690.021
post embryonic appendage morphogenesisGO:00351203850.021
proteolysis involved in cellular protein catabolic processGO:0051603830.021
positive regulation of signalingGO:00230562430.021
muscle tissue developmentGO:0060537300.020
defense responseGO:00069523000.020
notch signaling pathwayGO:00072191200.020
mitotic nuclear divisionGO:00070672130.020
positive regulation of cell communicationGO:00106472500.020
taxisGO:00423303040.020
positive regulation of transcription dna templatedGO:00458932660.020
regulation of localizationGO:00328792750.020
tube morphogenesisGO:00352391910.019
defense response to other organismGO:00985422250.019
regulation of cell deathGO:00109411730.019
Human Mouse
nuclear transportGO:0051169720.019
regulation of catabolic processGO:00098941700.019
organelle fissionGO:00482853400.019
anterior posterior pattern specificationGO:00099521360.019
positive regulation of multicellular organismal processGO:00512401430.019
axon developmentGO:00615642970.019
protein complex biogenesisGO:00702712010.018
negative regulation of developmental processGO:00510932010.018
chromosome segregationGO:00070591570.018
regulation of cell cycleGO:00517262910.018
Human
tripartite regional subdivisionGO:00073511030.018
regulation of microtubule cytoskeleton organizationGO:0070507410.018
secretionGO:00469031090.017
cytoskeleton dependent cytokinesisGO:0061640810.017
negative regulation of cell communicationGO:00106482230.017
Mouse
nucleocytoplasmic transportGO:0006913720.017
regulation of small gtpase mediated signal transductionGO:0051056930.017
regulation of programmed cell deathGO:00430671520.017
Human Mouse
regulation of molecular functionGO:00650092170.017
Human
rna interferenceGO:0016246270.017
regulation of immune responseGO:00507761180.016
phagocytosisGO:00069092150.016
cellular nitrogen compound catabolic processGO:00442701650.016
positive regulation of macromolecule metabolic processGO:00106044050.016
gene silencingGO:00164581380.016
regulation of phosphate metabolic processGO:00192202100.016
rrna processingGO:000636430.016
regulation of immune effector processGO:0002697520.016
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.016
positive regulation of rna biosynthetic processGO:19026802660.015
myoblast fusionGO:0007520430.015
phosphorylationGO:00163102940.015
protein processingGO:0016485680.015
Human
intracellular mrna localizationGO:0008298660.015
positive regulation of gene expressionGO:00106282900.014
muscle organ developmentGO:00075171270.014
skeletal muscle organ developmentGO:0060538480.014
axonogenesisGO:00074092900.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
oocyte axis specificationGO:00073091080.014
regulation of microtubule polymerization or depolymerizationGO:0031110270.014
eye morphogenesisGO:00485922600.014
cellular protein complex disassemblyGO:0043624350.014
endocytosisGO:00068973100.014
cytoplasm organizationGO:0007028640.014
positive regulation of cell motilityGO:200014730.014
endomembrane system organizationGO:00102561190.014
mitotic cytokinesisGO:0000281500.013
organophosphate metabolic processGO:00196371950.013
response to organic substanceGO:00100332840.013
positive regulation of cell deathGO:0010942690.013
protein complex disassemblyGO:0043241360.013
ras protein signal transductionGO:0007265880.013
regulation of neurogenesisGO:00507671580.013
regulation of defense response to bacteriumGO:1900424300.013
regulation of anatomical structure sizeGO:00900661630.013
intracellular protein transportGO:00068861040.013
establishment or maintenance of cell polarityGO:00071631670.013
regulation of proteasomal protein catabolic processGO:0061136390.013
photoreceptor cell differentiationGO:00465301700.012
protein catabolic processGO:00301631010.012
pole plasm rna localizationGO:0007316520.012
negative regulation of rna metabolic processGO:00512532510.012
sterol homeostasisGO:005509240.012
regulation of protein metabolic processGO:00512462560.012
Human
cellular component assembly involved in morphogenesisGO:00109271510.012
segmentationGO:00352822070.012
nucleobase containing compound catabolic processGO:00346551650.012
covalent chromatin modificationGO:00165691060.012
nucleoside phosphate metabolic processGO:00067531620.012
regulation of nervous system developmentGO:00519602480.012
biological adhesionGO:00226101380.012
positive regulation of biosynthetic processGO:00098913160.012
macromolecular complex disassemblyGO:0032984370.012
mrna catabolic processGO:0006402330.012
regulation of embryonic developmentGO:0045995680.012
g protein coupled receptor signaling pathwayGO:00071861360.012
regulation of cellular component sizeGO:0032535980.012
spindle organizationGO:00070512530.011
striated muscle myosin thick filament assemblyGO:007168830.011
antibacterial peptide productionGO:0002778220.011
cellular response to dna damage stimulusGO:00069742230.011
Human Mouse
maternal determination of anterior posterior axis embryoGO:0008358740.011
compound eye morphogenesisGO:00017452490.011
regulation of ras protein signal transductionGO:0046578930.011
tissue morphogenesisGO:00487292970.011
homeostatic processGO:00425921990.011
body morphogenesisGO:001017120.011
embryo development ending in birth or egg hatchingGO:00097921520.011
oocyte anterior posterior axis specificationGO:0007314720.011
regulation of cellular protein catabolic processGO:1903362440.011
muscle cell differentiationGO:00426921030.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
regulation of reproductive processGO:2000241540.011
developmental maturationGO:00217001720.011
negative regulation of notch signaling pathwayGO:0045746410.011
cell adhesionGO:00071551360.011
chromatin modificationGO:00165681470.011
single organism membrane organizationGO:0044802930.011
regulation of cellular amine metabolic processGO:003323830.011
nucleus organizationGO:0006997450.011
microtubule organizing center organizationGO:00310231680.010
sister chromatid segregationGO:0000819920.010
regulation of proteolysisGO:0030162870.010
Human
heterocycle catabolic processGO:00467001660.010
positive regulation of mapk cascadeGO:0043410630.010
cellular response to chemical stimulusGO:00708871990.010
negative regulation of signalingGO:00230572190.010
Mouse
developmental programmed cell deathGO:00106231380.010
oocyte differentiationGO:00099941450.010
actin filament polymerizationGO:0030041270.010
growthGO:00400073590.010
Human
centrosome organizationGO:00512971630.010
pole plasm oskar mrna localizationGO:0045451460.010
apoptotic processGO:00069151590.010
Human Mouse
organic acid metabolic processGO:00060821030.010
substrate adhesion dependent cell spreadingGO:003444620.010
protein transportGO:00150311550.010
regulation of intracellular signal transductionGO:19025312360.010
Mouse
positive regulation of organelle organizationGO:0010638650.010
cell divisionGO:00513012480.010

Ubp64E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
renal tubular transport diseaseDOID:44700.070
urinary system diseaseDOID:1800.070
kidney diseaseDOID:55700.070
disease of anatomical entityDOID:700.070
bartter diseaseDOID:44500.017
nervous system diseaseDOID:86300.013