Drosophila melanogaster

129 known processes

Atg7 (Dmel_CG5489)

Autophagy-specific gene 7

(Aliases: Dmel\CG5489,CG5489,atg7)

Atg7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval midgut histolysisGO:0035069220.993
response to starvationGO:0042594970.905
response to nutrient levelsGO:00316671140.892
response to extracellular stimulusGO:00099911160.876
cellular response to starvationGO:0009267610.875
organelle membrane fusionGO:0090174160.853
histolysisGO:00075591020.819
cellular response to extracellular stimulusGO:0031668640.771
macroautophagyGO:0016236420.765
larval midgut cell programmed cell deathGO:0035096190.736
tissue deathGO:00162711020.615
autophagic vacuole fusionGO:0000046150.585
autophagic vacuole assemblyGO:000004520.519
positive regulation of autophagyGO:0010508210.515
regulation of nurse cell apoptotic processGO:004547790.476
cellular catabolic processGO:00442483720.437
cellular response to external stimulusGO:0071496660.411
autophagyGO:00069141080.405
regulation of response to stressGO:00801342000.343
exocrine system developmentGO:00352721620.337
cellular response to nutrient levelsGO:0031669620.333
response to abiotic stimulusGO:00096283410.309
Human
immune system processGO:00023763470.306
regulation of immune system processGO:00026821760.299
peptide metabolic processGO:0006518800.259
response to other organismGO:00517072930.258
developmental programmed cell deathGO:00106231380.258
agingGO:00075681430.235
regulation of autophagyGO:0010506620.231
vesicle mediated transportGO:00161923810.219
cellular protein modification processGO:00064644380.212
gland developmentGO:00487321910.186
Mouse
programmed cell deathGO:00125012570.184
regulation of multi organism processGO:00439001310.182
catabolic processGO:00090564090.182
regulation of defense response to virusGO:0050688140.163
salivary gland morphogenesisGO:00074351450.161
autophagic cell deathGO:0048102830.157
single organism catabolic processGO:00447122280.157
skin developmentGO:0043588650.155
phagocytosisGO:00069092150.145
determination of adult lifespanGO:00083401370.144
salivary gland developmentGO:00074311620.142
protein modification processGO:00362114380.134
defense response to other organismGO:00985422250.129
salivary gland histolysisGO:0035070880.128
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.126
cell migrationGO:00164772380.126
deathGO:00162652840.125
organonitrogen compound metabolic processGO:19015643180.119
Mouse
endocytosisGO:00068973100.117
response to external biotic stimulusGO:00432072930.115
salivary gland cell autophagic cell deathGO:0035071830.107
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.107
gland morphogenesisGO:00226121450.106
epithelial cell differentiationGO:00308553220.105
organic substance transportGO:00717022570.104
regulation of cellular amino acid metabolic processGO:000652100.094
regulation of protein metabolic processGO:00512462560.093
Human Mouse
cell type specific apoptotic processGO:0097285380.093
response to bacteriumGO:00096171980.092
epithelial cell developmentGO:00020642740.090
regulation of macroautophagyGO:0016241150.089
actin filament based processGO:00300292200.089
single organism membrane fusionGO:0044801420.085
regulation of defense responseGO:00313471020.084
response to oxidative stressGO:0006979860.080
positive regulation of catabolic processGO:00098961050.077
small molecule metabolic processGO:00442813050.077
Mouse
single organism intracellular transportGO:19025822070.077
regulation of catalytic activityGO:00507901850.076
apoptotic process involved in developmentGO:1902742200.074
circadian rhythmGO:00076231050.071
regulation of multicellular organismal developmentGO:20000264140.071
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.069
regulation of immune responseGO:00507761180.066
regulation of catabolic processGO:00098941700.065
localization of cellGO:00516742570.062
negative regulation of notch signaling pathwayGO:0045746410.062
cellular response to oxidative stressGO:0034599280.061
regulation of cell cycleGO:00517262910.061
positive regulation of signal transductionGO:00099672230.061
hemopoiesisGO:0030097460.060
cellular amino acid metabolic processGO:0006520610.059
Mouse
innate immune responseGO:00450871440.058
negative regulation of erbb signaling pathwayGO:1901185290.057
response to inorganic substanceGO:0010035440.057
positive regulation of macromolecule biosynthetic processGO:00105572830.056
maintenance of locationGO:0051235730.053
cell deathGO:00082192790.052
regulation of cellular protein metabolic processGO:00322682430.051
Human Mouse
cellular response to arsenic containing substanceGO:007124360.051
carboxylic acid metabolic processGO:0019752920.051
Mouse
intracellular transportGO:00469072280.050
positive regulation of macroautophagyGO:001623980.049
regulation of tor signalingGO:0032006210.049
positive regulation of cellular protein metabolic processGO:00322701180.048
Human Mouse
epidermal growth factor receptor signaling pathwayGO:0007173580.048
sensory perceptionGO:00076001960.048
positive regulation of apoptotic signaling pathwayGO:200123540.048
defense response to bacteriumGO:00427421780.046
response to biotic stimulusGO:00096072940.046
regulation of cell differentiationGO:00455953020.046
regulation of localizationGO:00328792750.045
Mouse
secretionGO:00469031090.045
Mouse
response to heatGO:0009408630.045
negative regulation of growthGO:0045926840.044
locomotory behaviorGO:00076261760.044
Mouse
spermatid developmentGO:0007286980.044
regulation of erbb signaling pathwayGO:1901184420.043
response to paraquatGO:190156240.043
regulation of cell deathGO:00109411730.043
Human Mouse
regulation of cellular ketone metabolic processGO:001056530.043
amine metabolic processGO:0009308120.043
cellular homeostasisGO:0019725800.042
positive regulation of macromolecule metabolic processGO:00106044050.041
Human Mouse
positive regulation of intracellular signal transductionGO:19025331160.041
positive regulation of response to stimulusGO:00485843230.041
cellular ketone metabolic processGO:0042180240.040
cellular amine metabolic processGO:0044106120.039
notch signaling pathwayGO:00072191200.038
peptidyl lysine acetylationGO:0018394390.038
Mouse
regulation of molecular functionGO:00650092170.037
positive regulation of tor signalingGO:0032008130.037
organic acid metabolic processGO:00060821030.037
Mouse
positive regulation of transcription dna templatedGO:00458932660.037
epidermal cell differentiationGO:0009913510.036
regulation of growthGO:00400082330.036
kidney developmentGO:000182230.036
rna localizationGO:00064031150.035
regulation of nervous system developmentGO:00519602480.035
response to radiationGO:00093141550.035
regulation of protein ubiquitinationGO:0031396220.035
Mouse
chromatin modificationGO:00165681470.035
Mouse
positive regulation of nurse cell apoptotic processGO:004585050.035
protein acetylationGO:0006473390.034
Mouse
regulation of cellular amine metabolic processGO:003323830.034
nucleoside phosphate metabolic processGO:00067531620.034
establishment of localization in cellGO:00516494020.033
regulation of innate immune responseGO:0045088710.033
positive regulation of gene expressionGO:00106282900.033
phosphatidylinositol mediated signalingGO:004801540.033
phosphorylationGO:00163102940.033
response to organophosphorusGO:004668320.033
cell cycle phase transitionGO:00447701400.033
response to glucoseGO:000974920.032
immune effector processGO:0002252980.032
negative regulation of cellular component organizationGO:00511291080.032
Mouse
immune responseGO:00069552460.032
negative regulation of growth of symbiont involved in interaction with hostGO:004414690.031
asymmetric protein localization involved in cell fate determinationGO:004516790.031
regulation of cell cycle g1 s phase transitionGO:1902806230.031
positive regulation of cellular biosynthetic processGO:00313283160.030
imaginal disc derived wing hair organizationGO:0035317450.030
regulation of apoptotic processGO:00429811300.030
Human Mouse
metal ion homeostasisGO:0055065440.030
chromatin organizationGO:00063252070.030
Mouse
regulation of mitotic cell cycleGO:00073461900.030
cellular metal ion homeostasisGO:0006875310.029
neurological system processGO:00508773580.029
Mouse
defense responseGO:00069523000.029
cellular response to hexose stimulusGO:007133110.029
apoptotic processGO:00069151590.029
Human Mouse
translationGO:0006412690.029
imaginal disc derived appendage developmentGO:00487373990.028
response to monosaccharideGO:003428440.028
negative regulation of response to stimulusGO:00485852580.027
epidermis developmentGO:0008544650.027
post embryonic appendage morphogenesisGO:00351203850.027
positive regulation of developmental processGO:00510941430.027
covalent chromatin modificationGO:00165691060.027
Mouse
regulation of hydrolase activityGO:0051336970.027
inositol lipid mediated signalingGO:004801740.027
regulation of neurogenesisGO:00507671580.027
nitrogen compound transportGO:0071705850.026
lipid localizationGO:0010876540.026
cell maturationGO:00484691440.026
regulation of mitotic cell cycle phase transitionGO:19019901300.026
regulation of response to biotic stimulusGO:0002831630.026
lipid modificationGO:0030258240.026
oxoacid metabolic processGO:00434361030.026
Mouse
cellular lipid metabolic processGO:0044255830.026
protein heterooligomerizationGO:005129140.025
protein phosphorylationGO:00064681690.025
negative regulation of cell cycleGO:00457861160.025
cellularizationGO:0007349900.025
tube developmentGO:00352952440.025
regulation of locomotionGO:0040012420.025
negative regulation of nitrogen compound metabolic processGO:00511722650.025
wing disc morphogenesisGO:00074723440.025
regulation of immune effector processGO:0002697520.024
histone h4 acetylationGO:0043967130.024
Mouse
protein localization to organelleGO:0033365820.024
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.024
kidney morphogenesisGO:006099330.024
nephron developmentGO:007200630.024
organic substance catabolic processGO:19015753080.024
Human Mouse
multicellular organismal agingGO:00102591400.024
positive regulation of signalingGO:00230562430.024
positive regulation of cellular catabolic processGO:0031331950.023
regulation of cellular catabolic processGO:00313291570.023
regulation of reactive oxygen species metabolic processGO:200037780.023
tor signalingGO:0031929320.023
response to virusGO:0009615280.023
adult chitin containing cuticle pigmentationGO:0048085160.023
heart morphogenesisGO:0003007320.023
vesicle organizationGO:0016050440.023
ovarian follicle cell developmentGO:00307072480.023
sex differentiationGO:0007548810.022
cellular response to ethanolGO:007136140.022
chromosome organizationGO:00512763600.022
Mouse
appendage developmentGO:00487364010.022
negative regulation of cellular biosynthetic processGO:00313272770.022
positive regulation of cell communicationGO:00106472500.022
non sensory hair organizationGO:0035316470.022
homeostatic processGO:00425921990.022
protein secretionGO:0009306450.022
phosphatidylinositol 3 kinase signalingGO:001406540.022
tissue migrationGO:00901301550.022
regulation of intracellular signal transductionGO:19025312360.022
spermatid differentiationGO:00485151140.021
regulation of developmental growthGO:00486381740.021
molting cycleGO:0042303560.021
head developmentGO:00603221350.021
Mouse
columnar cuboidal epithelial cell developmentGO:00020662490.021
erbb signaling pathwayGO:0038127580.021
phosphatidylinositol phosphorylationGO:0046854100.021
defense response to gram negative bacteriumGO:0050829940.021
macromolecular complex assemblyGO:00650032560.021
regulation of translationGO:0006417560.020
endomembrane system organizationGO:00102561190.020
organelle assemblyGO:00709251980.020
vitamin biosynthetic processGO:000911010.020
regulation of cell developmentGO:00602842150.020
multi multicellular organism processGO:00447061230.020
mitochondrion degradationGO:000042280.020
digestive tract morphogenesisGO:00485461270.020
establishment of rna localizationGO:0051236470.019
cellular cation homeostasisGO:0030003380.019
intracellular signal transductionGO:00355563000.019
positive regulation of jnk cascadeGO:0046330160.019
apical constrictionGO:0003383180.019
protein modification by small protein conjugation or removalGO:00706471060.019
positive regulation of phosphorylationGO:0042327870.019
eggshell formationGO:00307031050.019
imaginal disc derived wing morphogenesisGO:00074763370.019
developmental pigmentationGO:0048066680.019
positive regulation of cell deathGO:0010942690.019
Human
positive regulation of catalytic activityGO:00430851180.019
positive regulation of immune responseGO:0050778630.019
purine nucleotide catabolic processGO:00061951090.019
axonogenesisGO:00074092900.018
Mouse
lipid phosphorylationGO:0046834110.018
mitotic dna damage checkpointGO:0044773740.018
negative regulation of cell cycle processGO:00109481090.018
cellular protein catabolic processGO:0044257830.018
nephron epithelium developmentGO:007200930.018
actin filament organizationGO:00070151260.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
ethanolamine containing compound metabolic processGO:004243940.018
growthGO:00400073590.018
cell cycle g1 s phase transitionGO:0044843310.018
imaginal disc derived appendage morphogenesisGO:00351143950.018
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
regulation of anatomical structure sizeGO:00900661630.018
epithelium migrationGO:00901321480.018
mitotic dna integrity checkpointGO:0044774750.018
lipid storageGO:0019915380.017
organonitrogen compound catabolic processGO:19015651280.017
positive regulation of endopeptidase activityGO:0010950260.017
axon developmentGO:00615642970.017
Mouse
positive regulation of rna metabolic processGO:00512542710.017
positive regulation of cell migrationGO:003033520.017
chemical homeostasisGO:0048878920.017
cellular divalent inorganic cation homeostasisGO:0072503230.017
positive regulation of jun kinase activityGO:004350740.017
negative regulation of mitotic cell cycleGO:00459301090.016
actin cytoskeleton organizationGO:00300362060.016
gastrulation with mouth forming firstGO:0001703360.016
response to temperature stimulusGO:00092661060.016
membrane fusionGO:0061025420.016
protein modification by small protein conjugationGO:0032446790.016
circulatory system developmentGO:0072359820.016
Mouse
histone acetylationGO:0016573380.016
Mouse
rna transportGO:0050658460.016
nurse cell apoptotic processGO:0045476170.016
apical constriction involved in gastrulationGO:000338470.016
vesicle localizationGO:0051648550.016
appendage morphogenesisGO:00351073970.016
immune system developmentGO:0002520570.016
somatic muscle developmentGO:0007525660.016
cation transportGO:00068121100.016
larval developmentGO:00021641040.016
mitotic cell cycle phase transitionGO:00447721380.016
regulation of cellular component sizeGO:0032535980.016
membrane organizationGO:00610241120.016
Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.015
skeletal muscle organ developmentGO:0060538480.015
dna integrity checkpointGO:0031570810.015
lipid metabolic processGO:00066291210.015
nuclear divisionGO:00002803320.015
nephron tubule formationGO:007207930.015
modification dependent protein catabolic processGO:0019941780.015
developmental maturationGO:00217001720.015
proteolysisGO:00065081920.015
regulation of protein modification processGO:00313991120.015
Human Mouse
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.015
cell motilityGO:00488702510.015
response to oxygen containing compoundGO:19017002000.015
protein transportGO:00150311550.015
response to woundingGO:0009611940.015
endosomal transportGO:0016197440.015
negative regulation of cell cycle phase transitionGO:19019881030.015
secretion by cellGO:00329401010.015
regulation of neuron differentiationGO:00456641030.015
negative regulation of developmental growthGO:0048640640.014
regulation of cell divisionGO:0051302720.014
necrotic cell deathGO:007026510.014
regulation of notch signaling pathwayGO:00085931000.014
regulation of developmental pigmentationGO:0048070240.014
hormone catabolic processGO:004244730.014
cell junction organizationGO:0034330570.014
positive regulation of defense responseGO:0031349590.014
regulation of cell cycle processGO:00105641810.014
response to hexoseGO:000974630.014
heart developmentGO:0007507820.014
Mouse
glycerophospholipid metabolic processGO:0006650230.014
positive regulation of multicellular organismal processGO:00512401430.014
Mouse
proteolysis involved in cellular protein catabolic processGO:0051603830.014
positive regulation of multi organism processGO:0043902400.014
negative regulation of cell communicationGO:00106482230.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
negative regulation of developmental processGO:00510932010.014
protein ubiquitinationGO:0016567700.014
Mouse
spermatogenesisGO:00072832000.014
positive regulation of mapk cascadeGO:0043410630.014
response to copper ionGO:004668840.014
modification dependent macromolecule catabolic processGO:0043632790.014
regulation of epithelial cell proliferationGO:005067840.014
adult locomotory behaviorGO:0008344760.014
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.014
histone h4 k16 acetylationGO:004398440.013
Mouse
compound eye morphogenesisGO:00017452490.013
regulation of response to oxidative stressGO:190288240.013
cation homeostasisGO:0055080510.013
positive regulation of proteolysisGO:0045862520.013
cellular response to carbohydrate stimulusGO:007132240.013
hair cell differentiationGO:0035315470.013
organelle fissionGO:00482853400.013
positive regulation of response to external stimulusGO:0032103440.013
response to organic substanceGO:00100332840.013
membrane invaginationGO:0010324110.013
adult behaviorGO:00305341370.013
Mouse
peptidyl lysine modificationGO:0018205570.013
Mouse
regulation of anatomical structure morphogenesisGO:00226032420.013
protein complex biogenesisGO:00702712010.013
regulation of sequestering of calcium ionGO:005128230.013
neuron remodelingGO:0016322290.013
maintenance of location in cellGO:0051651280.013
cellular ion homeostasisGO:0006873390.012
positive regulation of phosphorus metabolic processGO:00105621390.012
negative regulation of homeostatic processGO:003284520.012
regulation of cytoskeleton organizationGO:0051493890.012
ras protein signal transductionGO:0007265880.012
single organism biosynthetic processGO:00447112060.012
kidney epithelium developmentGO:007207330.012
gastrulationGO:0007369700.012
nucleobase containing compound transportGO:0015931560.012
connective tissue developmentGO:006144830.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
cellular response to sterol depletionGO:007150130.012
mapk cascadeGO:00001651070.012
pole cell developmentGO:0007277260.012
dna damage checkpointGO:0000077780.012
protein catabolic processGO:00301631010.012
Human Mouse
germ line stem cell maintenanceGO:0030718500.012
positive regulation of nitrogen compound metabolic processGO:00511733540.012
induction of programmed cell death by ecdysoneGO:0035078120.012
regulation of stress activated mapk cascadeGO:0032872410.012
positive regulation of cellular component organizationGO:00511301560.012
regulation of endocytosisGO:0030100370.012
dendrite morphogenesisGO:00488131990.012
endosome organizationGO:000703290.012
muscle organ developmentGO:00075171270.012
positive regulation of protein metabolic processGO:00512471280.012
Human Mouse
negative regulation of cellular metabolic processGO:00313243820.012
Mouse
positive regulation of apoptotic processGO:0043065470.012
Human
response to metal ionGO:0010038230.012
membrane lipid metabolic processGO:0006643220.012
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.012
response to reactive oxygen speciesGO:0000302240.012
germarium derived female germ line cyst formationGO:0030727420.012
eye antennal disc developmentGO:0035214600.012
internal peptidyl lysine acetylationGO:0018393380.012
Mouse
establishment or maintenance of cytoskeleton polarityGO:0030952440.012
cytosolic calcium ion transportGO:006040120.012
oocyte microtubule cytoskeleton polarizationGO:0008103220.012
cytoplasmic transportGO:00164821300.011
regulation of response to external stimulusGO:00321011150.011
negative regulation of cell cycle g1 s phase transitionGO:1902807130.011
positive regulation of immune system processGO:0002684680.011
mitotic nuclear divisionGO:00070672130.011
eye pigment granule organizationGO:0008057120.011
release of sequestered calcium ion into cytosolGO:005120910.011
acetylcholine metabolic processGO:000829120.011
positive regulation of cell differentiationGO:0045597640.011
regulation of gene expression epigeneticGO:00400291280.011
cellular pigmentationGO:0033059120.011
regulation of secretionGO:0051046440.011
Mouse
positive regulation of peptidase activityGO:0010952290.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
dendrite developmentGO:00163582040.011
humoral immune responseGO:00069591170.011
sensory perception of chemical stimulusGO:00076061160.011
positive regulation of protein phosphorylationGO:0001934340.011
chorion containing eggshell formationGO:00073041050.011
oocyte maturationGO:000155630.011
actin mediated cell contractionGO:0070252210.011
epithelial cell morphogenesis involved in gastrulationGO:000338170.011
cellular response to mechanical stimulusGO:007126020.011
carbohydrate metabolic processGO:0005975820.011
regulation of cellular response to stressGO:0080135890.011
regulation of cellular response to oxidative stressGO:190040740.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
response to ionizing radiationGO:0010212320.011
cellular chemical homeostasisGO:0055082400.011
pigment granule organizationGO:0048753120.011
endosome to lysosome transportGO:000833370.011
purine nucleoside metabolic processGO:00422781270.011
cardiovascular system developmentGO:0072358820.011
Mouse
peptidyl amino acid modificationGO:00181931050.011
Mouse
positive regulation of rna biosynthetic processGO:19026802660.011
divalent inorganic cation homeostasisGO:0072507290.010
acetylcholine catabolic processGO:000658110.010
interspecies interaction between organismsGO:0044419160.010
Mouse
nephron epithelium morphogenesisGO:007208830.010
response to hypoxiaGO:0001666530.010
positive regulation of cell motilityGO:200014730.010
protein targeting to nucleusGO:0044744510.010
stress activated mapk cascadeGO:0051403520.010
cell fate determinationGO:0001709910.010
regulation of transportGO:00510491810.010
Mouse
organic hydroxy compound metabolic processGO:1901615830.010
regulation of compound eye retinal cell programmed cell deathGO:0046669180.010
positive regulation of hydrolase activityGO:0051345780.010
pigment metabolic processGO:0042440840.010
positive regulation of endocytosisGO:0045807220.010

Atg7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.121
nervous system diseaseDOID:86300.023
disease of cellular proliferationDOID:1456600.012
cardiovascular system diseaseDOID:128700.010
central nervous system diseaseDOID:33100.010