Drosophila melanogaster

52 known processes

Nak (Dmel_CG10637)

Numb-associated kinase

(Aliases: nak,CG10637,Dmel\CG10637)

Nak biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
microtubule organizing center organizationGO:00310231680.383
cellular protein modification processGO:00064644380.297
Human Yeast Mouse Rat
centrosome organizationGO:00512971630.223
regulation of cell differentiationGO:00455953020.151
imaginal disc derived appendage morphogenesisGO:00351143950.107
homeostatic processGO:00425921990.094
negative regulation of gene expressionGO:00106293870.090
regulation of cell developmentGO:00602842150.074
regulation of nervous system developmentGO:00519602480.069
positive regulation of dendrite morphogenesisGO:005077590.069
regulation of notch signaling pathwayGO:00085931000.067
Human
adult locomotory behaviorGO:0008344760.066
regulation of phosphorylationGO:00423251470.066
negative regulation of cell communicationGO:00106482230.060
regulation of cellular localizationGO:00603411360.058
response to abiotic stimulusGO:00096283410.055
rho protein signal transductionGO:0007266140.054
protein modification processGO:00362114380.051
Human Yeast Mouse Rat
deathGO:00162652840.050
catabolic processGO:00090564090.050
imaginal disc derived wing morphogenesisGO:00074763370.049
protein phosphorylationGO:00064681690.047
Human Yeast Mouse Rat
regulation of microtubule cytoskeleton organizationGO:0070507410.045
negative regulation of developmental processGO:00510932010.044
negative regulation of cellular metabolic processGO:00313243820.042
spermatogenesisGO:00072832000.042
centrosome cycleGO:00070981370.042
response to starvationGO:0042594970.040
regulation of nurse cell apoptotic processGO:004547790.040
regulation of neuron differentiationGO:00456641030.039
regulation of transcription from rna polymerase ii promoterGO:00063573780.038
spermatid differentiationGO:00485151140.038
positive regulation of signalingGO:00230562430.038
Human
microtubule polymerization or depolymerizationGO:0031109390.037
phosphorylationGO:00163102940.036
Human Yeast Mouse Rat
single organism cellular localizationGO:19025801800.035
response to nutrient levelsGO:00316671140.034
heterochromatin organizationGO:0070828250.034
regulation of intracellular signal transductionGO:19025312360.034
protein complex disassemblyGO:0043241360.034
cell cell signaling involved in cell fate commitmentGO:00451682100.033
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.033
regulation of neurogenesisGO:00507671580.032
negative regulation of rna biosynthetic processGO:19026792400.032
positive regulation of cellular biosynthetic processGO:00313283160.031
developmental maturationGO:00217001720.031
oocyte developmentGO:00485991240.031
negative regulation of macromolecule biosynthetic processGO:00105582700.030
endocytosisGO:00068973100.030
negative regulation of cell differentiationGO:00455961430.029
regulation of microtubule polymerization or depolymerizationGO:0031110270.029
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.029
protein transportGO:00150311550.028
single organism intracellular transportGO:19025822070.027
transmembrane transportGO:00550851390.027
negative regulation of nitrogen compound metabolic processGO:00511722650.026
regulation of microtubule based processGO:0032886490.026
cellular catabolic processGO:00442483720.026
vesicle mediated transportGO:00161923810.025
regulation of cellular catabolic processGO:00313291570.025
immune effector processGO:0002252980.025
developmental programmed cell deathGO:00106231380.024
negative regulation of microtubule depolymerizationGO:0007026210.024
nucleocytoplasmic transportGO:0006913720.024
response to oxygen containing compoundGO:19017002000.023
positive regulation of signal transductionGO:00099672230.023
Human
tube morphogenesisGO:00352391910.023
maintenance of locationGO:0051235730.022
autophagic cell deathGO:0048102830.022
regulation of hydrolase activityGO:0051336970.022
negative regulation of multicellular organismal processGO:00512411420.022
regulation of localizationGO:00328792750.022
organonitrogen compound metabolic processGO:19015643180.022
response to heatGO:0009408630.022
salivary gland histolysisGO:0035070880.022
meiosis iGO:0007127590.021
regulation of phosphorus metabolic processGO:00511742100.021
negative regulation of signal transductionGO:00099682060.021
negative regulation of protein metabolic processGO:0051248850.021
oocyte differentiationGO:00099941450.021
positive regulation of response to stimulusGO:00485843230.021
Human
regulation of transferase activityGO:0051338580.021
carbohydrate derivative metabolic processGO:19011352170.021
cell cycle checkpointGO:0000075950.021
cell maturationGO:00484691440.020
regulation of phosphate metabolic processGO:00192202100.020
mapk cascadeGO:00001651070.020
oxoacid metabolic processGO:00434361030.020
response to extracellular stimulusGO:00099911160.020
protein complex assemblyGO:00064612000.020
negative regulation of cell developmentGO:0010721620.020
microtubule depolymerizationGO:0007019250.019
negative regulation of cellular protein metabolic processGO:0032269850.019
regulation of microtubule depolymerizationGO:0031114240.019
pigment cell differentiationGO:005093130.018
dna integrity checkpointGO:0031570810.018
imaginal disc derived wing vein morphogenesisGO:0008586440.018
detection of stimulusGO:00516061560.018
positive regulation of cellular catabolic processGO:0031331950.018
regulation of transportGO:00510491810.018
multi organism reproductive behaviorGO:00447051210.018
atp catabolic processGO:0006200380.018
positive regulation of exocytosisGO:004592140.018
dna damage checkpointGO:0000077780.017
purine nucleotide metabolic processGO:00061631460.017
positive regulation of jun kinase activityGO:004350740.017
meiotic cell cycle processGO:19030461320.017
cell cycle phase transitionGO:00447701400.017
gene silencingGO:00164581380.017
positive regulation of cellular protein metabolic processGO:00322701180.017
cellular protein complex disassemblyGO:0043624350.017
protein complex biogenesisGO:00702712010.017
imaginal disc derived wing vein specificationGO:0007474480.017
intracellular transportGO:00469072280.017
nucleoside triphosphate metabolic processGO:00091411200.017
positive regulation of nucleobase containing compound metabolic processGO:00459353320.016
organic acid metabolic processGO:00060821030.016
meiotic chromosome segregationGO:0045132590.016
regulation of organ morphogenesisGO:2000027780.016
cellular response to chemical stimulusGO:00708871990.016
regulation of gtp catabolic processGO:0033124440.015
negative regulation of response to stimulusGO:00485852580.015
carbohydrate derivative catabolic processGO:19011361180.015
digestive tract developmentGO:00485651490.015
regulation of catalytic activityGO:00507901850.015
Mouse
apoptotic processGO:00069151590.015
positive regulation of nitrogen compound metabolic processGO:00511733540.015
spermatid developmentGO:0007286980.015
regulation of protein complex disassemblyGO:0043244290.015
chromatin remodelingGO:0006338720.015
chromosome condensationGO:0030261410.015
tissue deathGO:00162711020.015
positive regulation of macromolecule biosynthetic processGO:00105572830.014
cellular pigmentationGO:0033059120.014
organelle localizationGO:00516401480.014
regulation of multi organism processGO:00439001310.014
multicellular organismal agingGO:00102591400.014
regulation of protein phosphorylationGO:0001932640.014
cellular amide metabolic processGO:0043603800.014
skeletal muscle organ developmentGO:0060538480.014
positive regulation of nervous system developmentGO:0051962690.014
cellular response to oxygen containing compoundGO:1901701790.014
protein targeting to nucleusGO:0044744510.014
tube developmentGO:00352952440.014
telomere maintenanceGO:0000723210.013
regulation of hemocyte proliferationGO:0035206370.013
response to monosaccharideGO:003428440.013
negative regulation of transcription dna templatedGO:00458922370.013
organic substance transportGO:00717022570.013
centrosome duplicationGO:00512981210.013
protein modification by small protein conjugation or removalGO:00706471060.013
regulation of cell cycleGO:00517262910.013
germarium derived egg chamber formationGO:00072931010.013
positive regulation of cell differentiationGO:0045597640.013
heterocycle catabolic processGO:00467001660.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
positive regulation of intracellular signal transductionGO:19025331160.013
dna geometric changeGO:0032392160.013
purine ribonucleoside metabolic processGO:00461281270.013
positive regulation of rac gtpase activityGO:003285580.013
programmed cell deathGO:00125012570.012
purine ribonucleoside catabolic processGO:00461301120.012
protein alkylationGO:0008213430.012
positive regulation of apoptotic processGO:0043065470.012
ras protein signal transductionGO:0007265880.012
response to endogenous stimulusGO:00097191190.012
regulation of mapk cascadeGO:0043408920.012
cell deathGO:00082192790.012
chromatin organizationGO:00063252070.012
small molecule metabolic processGO:00442813050.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
organic substance catabolic processGO:19015753080.012
regulation of rho protein signal transductionGO:0035023200.012
peptidyl amino acid modificationGO:00181931050.012
regulation of vesicle mediated transportGO:0060627590.012
regulation of heterochromatin assemblyGO:003144580.012
methylationGO:0032259470.012
mitotic cell cycle checkpointGO:0007093880.012
intracellular signal transductionGO:00355563000.012
regulation of mitotic cell cycle phase transitionGO:19019901300.011
endomembrane system organizationGO:00102561190.011
cellular response to starvationGO:0009267610.011
single organism catabolic processGO:00447122280.011
regulation of proteolysisGO:0030162870.011
regulation of endocytosisGO:0030100370.011
positive regulation of rna biosynthetic processGO:19026802660.011
rna catabolic processGO:0006401370.011
signal transduction in response to dna damageGO:004277030.011
polyol biosynthetic processGO:004617330.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
positive regulation of cell developmentGO:0010720610.011
negative regulation of erbb signaling pathwayGO:1901185290.011
macromolecular complex assemblyGO:00650032560.011
mitotic cell cycle phase transitionGO:00447721380.011
cellular response to abiotic stimulusGO:0071214580.011
regulation of ras protein signal transductionGO:0046578930.011
nucleoside metabolic processGO:00091161270.011
dna methylation or demethylationGO:004472840.011
regulation of reproductive processGO:2000241540.011
immune system processGO:00023763470.011
negative regulation of biosynthetic processGO:00098902770.011
actin filament based processGO:00300292200.010
Yeast
organ formationGO:0048645390.010
gtp metabolic processGO:0046039720.010
protein processingGO:0016485680.010
small gtpase mediated signal transductionGO:0007264880.010
regulation of intracellular transportGO:0032386640.010
divalent metal ion transportGO:0070838260.010
pigmentationGO:0043473750.010
cytoplasmic transportGO:00164821300.010
positive regulation of cell communicationGO:00106472500.010
Human
cellular macromolecular complex assemblyGO:00346221530.010
innate immune responseGO:00450871440.010
purine ribonucleoside triphosphate metabolic processGO:00092051190.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
ribonucleoside catabolic processGO:00424541120.010
positive regulation of phosphorus metabolic processGO:00105621390.010
positive regulation of cellular amino acid metabolic processGO:004576400.010

Nak disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012
urinary system diseaseDOID:1800.011
kidney diseaseDOID:55700.011