Drosophila melanogaster

7 known processes

Rpn6 (Dmel_CG10149)

Proteasome p44.5 subunit

(Aliases: Pros44.5,BcDNA.LD18931,Dmel\CG10149,CG10149,BcDNA:LD18931,p42B,l(2)k00103)

Rpn6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of proteasomal protein catabolic processGO:1901800200.853
modification dependent macromolecule catabolic processGO:0043632790.845
Human Yeast Worm
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.623
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.568
ubiquitin dependent protein catabolic processGO:0006511780.545
Human Yeast Worm
cellular macromolecule catabolic processGO:00442651360.472
Human Yeast Worm
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.466
proteasome assemblyGO:004324820.455
Human Yeast Worm
proteolysisGO:00065081920.432
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.420
columnar cuboidal epithelial cell developmentGO:00020662490.387
positive regulation of proteolysisGO:0045862520.371
chemotaxisGO:00069352490.360
proteolysis involved in cellular protein catabolic processGO:0051603830.333
Human Yeast Worm
modification dependent protein catabolic processGO:0019941780.307
Human Yeast Worm
er associated ubiquitin dependent protein catabolic processGO:003043330.280
protein catabolic processGO:00301631010.275
Human Yeast Worm
positive regulation of endopeptidase activityGO:0010950260.275
determination of adult lifespanGO:00083401370.263
Worm
proteasomal protein catabolic processGO:0010498590.238
positive regulation of peptidase activityGO:0010952290.220
catabolic processGO:00090564090.210
Human Yeast Worm
cell proliferationGO:00082832990.207
autophagyGO:00069141080.193
macromolecule catabolic processGO:00090571610.189
Human Yeast Worm
rna catabolic processGO:0006401370.182
cullin deneddylationGO:001038830.178
spindle elongationGO:0051231830.174
neuron remodelingGO:0016322290.162
central nervous system developmentGO:00074172010.161
body morphogenesisGO:001017120.155
columnar cuboidal epithelial cell differentiationGO:00020652560.154
larval developmentGO:00021641040.154
Worm
multicellular organismal agingGO:00102591400.154
Worm
positive regulation of cellular component biogenesisGO:0044089800.149
positive regulation of catabolic processGO:00098961050.146
protein modification by small protein conjugation or removalGO:00706471060.142
regulation of endopeptidase activityGO:0052548360.131
cellular response to dna damage stimulusGO:00069742230.124
mitotic spindle elongationGO:0000022810.123
protein k48 linked ubiquitinationGO:007093630.110
cellular protein catabolic processGO:0044257830.109
Human Yeast Worm
embryo development ending in birth or egg hatchingGO:00097921520.106
Worm
protein deneddylationGO:000033880.099
dendrite developmentGO:00163582040.098
regulation of catabolic processGO:00098941700.097
regulation of cellular protein metabolic processGO:00322682430.096
neuron projection guidanceGO:00974852410.096
ovarian follicle cell developmentGO:00307072480.095
mushroom body developmentGO:0016319700.094
organic substance catabolic processGO:19015753080.091
Human Yeast Worm
protein ubiquitinationGO:0016567700.090
regulation of cell cycleGO:00517262910.089
compound eye photoreceptor cell differentiationGO:00017511400.089
wing disc morphogenesisGO:00074723440.087
regulation of proteasomal protein catabolic processGO:0061136390.086
axon midline choice point recognitionGO:0016199260.085
mitotic nuclear divisionGO:00070672130.085
regulation of proteolysisGO:0030162870.084
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.084
neuron maturationGO:0042551310.082
protein complex biogenesisGO:00702712010.082
Human Yeast Worm
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.082
positive regulation of cellular component organizationGO:00511301560.081
regulation of peptidase activityGO:0052547390.076
spindle assemblyGO:0051225800.073
posttranscriptional gene silencing by rnaGO:0035194450.070
cellular catabolic processGO:00442483720.069
Human Yeast Worm
regulation of cell developmentGO:00602842150.059
regulation of cellular catabolic processGO:00313291570.059
deathGO:00162652840.057
Worm
regulation of molecular functionGO:00650092170.057
synapse organizationGO:00508081960.056
positive regulation of cellular protein metabolic processGO:00322701180.055
protein modification processGO:00362114380.053
ribonucleotide metabolic processGO:00092591450.052
regulation of mitotic cell cycleGO:00073461900.051
positive regulation of protein complex assemblyGO:0031334220.051
regulation of multi organism processGO:00439001310.050
regulation of protein catabolic processGO:0042176550.049
cell deathGO:00082192790.049
Worm
glycosyl compound metabolic processGO:19016571270.048
protein modification by small protein conjugationGO:0032446790.048
gene silencing by rnaGO:0031047570.047
neuromuscular synaptic transmissionGO:0007274670.047
compound eye developmentGO:00487493070.047
regulation of transforming growth factor beta receptor signaling pathwayGO:001701560.047
cellular protein modification processGO:00064644380.047
purine containing compound catabolic processGO:00725231120.046
regulation of cell differentiationGO:00455953020.045
eye developmentGO:00016543230.045
regulation of cellular protein catabolic processGO:1903362440.045
negative regulation of gene expressionGO:00106293870.045
endosome to lysosome transportGO:000833370.044
positive regulation of rna biosynthetic processGO:19026802660.044
protein modification by small protein removalGO:0070646280.044
cell divisionGO:00513012480.044
positive regulation of transcription dna templatedGO:00458932660.043
cellular macromolecular complex assemblyGO:00346221530.043
Human Yeast Worm
positive regulation of protein catabolic processGO:0045732340.043
regulation of protein complex assemblyGO:0043254420.042
regulation of cellular component sizeGO:0032535980.042
purine ribonucleotide catabolic processGO:00091541090.042
negative regulation of transcription dna templatedGO:00458922370.042
regulation of response to stressGO:00801342000.042
regulation of catalytic activityGO:00507901850.042
lamellipodium assemblyGO:0030032210.041
eggshell formationGO:00307031050.041
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.040
agingGO:00075681430.040
Worm
endosomal vesicle fusionGO:003405840.039
axon guidanceGO:00074112330.039
regulation of cellular component biogenesisGO:00440872010.039
macromolecular complex assemblyGO:00650032560.038
Human Yeast Worm
dendrite morphogenesisGO:00488131990.038
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589810.038
brain developmentGO:00074201200.037
positive regulation of cellular catabolic processGO:0031331950.037
positive regulation of mitotic cell cycleGO:0045931340.037
stem cell differentiationGO:00488631170.037
Human
phosphorylationGO:00163102940.036
response to abiotic stimulusGO:00096283410.036
regulation of epithelial cell proliferationGO:005067840.035
tissue deathGO:00162711020.035
cellular protein complex assemblyGO:0043623710.034
Human Yeast Worm
stem cell divisionGO:0017145690.034
regulation of lamellipodium organizationGO:1902743150.034
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:003114610.034
organophosphate metabolic processGO:00196371950.034
ribose phosphate metabolic processGO:00196931450.034
compound eye photoreceptor developmentGO:0042051780.033
posttranscriptional regulation of gene expressionGO:00106081450.033
nucleoside triphosphate metabolic processGO:00091411200.033
compound eye morphogenesisGO:00017452490.033
epithelial cell developmentGO:00020642740.032
double strand break repairGO:0006302260.032
positive regulation of protein metabolic processGO:00512471280.031
positive regulation of autophagyGO:0010508210.031
positive regulation of nucleobase containing compound metabolic processGO:00459353320.031
lipid storageGO:0019915380.031
multicellular organismal reproductive behaviorGO:00330571100.031
mitotic dna damage checkpointGO:0044773740.030
dna damage checkpointGO:0000077780.030
nuclear divisionGO:00002803320.030
dna templated transcriptional preinitiation complex assemblyGO:0070897200.030
apoptotic processGO:00069151590.030
Worm
regulation of multicellular organismal developmentGO:20000264140.030
cuticle pigmentationGO:0048067220.030
organelle assemblyGO:00709251980.029
mitotic g2 m transition checkpointGO:0044818700.029
regulation of dna templated transcription elongationGO:0032784170.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.029
cell maturationGO:00484691440.029
response to transforming growth factor betaGO:0071559180.029
response to ionizing radiationGO:0010212320.028
regulation of stem cell proliferationGO:0072091400.028
homeostatic processGO:00425921990.028
aromatic compound catabolic processGO:00194391660.027
regulation of cellular response to stressGO:0080135890.027
positive regulation of molecular functionGO:00440931360.027
purine nucleotide metabolic processGO:00061631460.027
response to organic substanceGO:00100332840.027
positive regulation of cell cycleGO:0045787430.027
regulation of neuron differentiationGO:00456641030.026
microtubule organizing center organizationGO:00310231680.026
histone ubiquitinationGO:001657440.026
ribonucleotide catabolic processGO:00092611090.026
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.026
heterocycle catabolic processGO:00467001660.026
nucleobase containing compound catabolic processGO:00346551650.025
regulation of synapse assemblyGO:0051963940.025
axonogenesisGO:00074092900.025
single organism catabolic processGO:00447122280.025
rna interferenceGO:0016246270.025
positive regulation of rna metabolic processGO:00512542710.025
establishment of protein localizationGO:00451841630.025
small gtpase mediated signal transductionGO:0007264880.025
regulation of protein metabolic processGO:00512462560.025
sensory organ morphogenesisGO:00905962600.024
small molecule metabolic processGO:00442813050.024
regulation of hydrolase activityGO:0051336970.024
stem cell developmentGO:0048864790.024
nucleobase containing small molecule metabolic processGO:00550861740.024
negative regulation of cellular response to growth factor stimulusGO:009028860.023
male gamete generationGO:00482322010.023
synaptic transmissionGO:00072682880.023
positive regulation of catalytic activityGO:00430851180.023
gene silencingGO:00164581380.023
transcription initiation from rna polymerase ii promoterGO:0006367250.023
ribonucleoside triphosphate catabolic processGO:00092031080.023
endomembrane system organizationGO:00102561190.022
negative regulation of signalingGO:00230572190.022
protein complex disassemblyGO:0043241360.022
dna templated transcription elongationGO:0006354180.022
mesenchymal cell differentiationGO:004876210.022
axon developmentGO:00615642970.021
positive regulation of hydrolase activityGO:0051345780.021
negative regulation of cellular biosynthetic processGO:00313272770.021
cellular protein complex disassemblyGO:0043624350.021
stem cell proliferationGO:0072089880.021
regulation of transcription elongation from rna polymerase ii promoterGO:0034243150.021
nucleotide metabolic processGO:00091171610.021
oocyte microtubule cytoskeleton polarizationGO:0008103220.021
regulation of phosphate metabolic processGO:00192202100.020
spindle assembly involved in mitosisGO:0090307500.020
spermatid differentiationGO:00485151140.020
chromosome segregationGO:00070591570.020
positive regulation of cellular biosynthetic processGO:00313283160.019
regulation of intracellular signal transductionGO:19025312360.019
head developmentGO:00603221350.019
mitotic dna integrity checkpointGO:0044774750.019
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.019
lamellipodium organizationGO:0097581210.019
synapse assemblyGO:00074161430.019
taxisGO:00423303040.019
eye photoreceptor cell differentiationGO:00017541450.019
negative regulation of signal transductionGO:00099682060.019
positive regulation of cell cycle processGO:0090068280.019
maintenance of locationGO:0051235730.018
protein complex assemblyGO:00064612000.018
Human Yeast Worm
regulation of bmp signaling pathwayGO:0030510230.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.018
eye photoreceptor cell developmentGO:0042462810.018
organophosphate catabolic processGO:00464341120.018
eye morphogenesisGO:00485922600.018
purine containing compound metabolic processGO:00725211550.018
protein localizationGO:00081042840.017
cell recognitionGO:00080371020.017
glycosyl compound catabolic processGO:19016581120.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
positive regulation of phosphorus metabolic processGO:00105621390.017
multi organism behaviorGO:00517051750.017
regulation of ras protein signal transductionGO:0046578930.017
regulation of establishment of protein localizationGO:0070201610.016
regulation of gene expression epigeneticGO:00400291280.016
dna templated transcription initiationGO:0006352250.016
nucleoside metabolic processGO:00091161270.016
regulation of autophagyGO:0010506620.016
defense response to virusGO:0051607230.016
ribonucleoside catabolic processGO:00424541120.016
mesenchymal cell developmentGO:001403110.016
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.016
tube developmentGO:00352952440.016
positive regulation of cellular protein catabolic processGO:1903364240.015
multi multicellular organism processGO:00447061230.015
negative regulation of biosynthetic processGO:00098902770.015
early endosome to late endosome transportGO:004502230.015
negative regulation of cellular protein metabolic processGO:0032269850.015
histone h2a ubiquitinationGO:003352220.015
actin filament cappingGO:005169320.015
regulation of protein localizationGO:0032880760.015
positive regulation of gene expressionGO:00106282900.015
photoreceptor cell developmentGO:0042461960.014
purine nucleotide catabolic processGO:00061951090.014
larval midgut cell programmed cell deathGO:0035096190.014
purine nucleoside catabolic processGO:00061521120.014
dna metabolic processGO:00062592270.014
negative regulation of nucleic acid templated transcriptionGO:19035072400.014
mitochondrion organizationGO:0007005650.014
regulation of cell divisionGO:0051302720.014
female sex differentiationGO:0046660200.014
chorion containing eggshell formationGO:00073041050.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
synaptic vesicle recyclingGO:0036465280.014
nucleoside phosphate metabolic processGO:00067531620.014
transcription from rna polymerase ii promoterGO:00063663680.014
pigment biosynthetic processGO:0046148360.014
eggshell chorion gene amplificationGO:000730790.014
regulation of phosphorus metabolic processGO:00511742100.014
ras protein signal transductionGO:0007265880.013
camera type eye morphogenesisGO:004859320.013
macroautophagyGO:0016236420.013
transcription elongation from rna polymerase ii promoterGO:0006368180.013
cellular component disassemblyGO:0022411460.013
cell cycle phase transitionGO:00447701400.013
guanosine containing compound catabolic processGO:1901069740.013
positive regulation of organelle organizationGO:0010638650.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
cellularizationGO:0007349900.013
regulation of transportGO:00510491810.013
nuclear migrationGO:0007097200.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.013
histolysisGO:00075591020.013
regulation of protein stabilityGO:0031647430.013
cytoplasmic transportGO:00164821300.013
regulation of anatomical structure sizeGO:00900661630.013
protein deubiquitinationGO:0016579170.012
protein transportGO:00150311550.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.012
negative regulation of cell proliferationGO:0008285690.012
mrna catabolic processGO:0006402330.012
regulation of response to extracellular stimulusGO:0032104180.012
nucleoside catabolic processGO:00091641120.012
epithelial cell migrationGO:00106311480.012
synaptic growth at neuromuscular junctionGO:00511241190.012
negative regulation of developmental processGO:00510932010.012
heart developmentGO:0007507820.012
wnt signaling pathwayGO:0016055980.012
determination of dorsal ventral asymmetryGO:004826230.012
negative regulation of cellular metabolic processGO:00313243820.012
imaginal disc derived leg morphogenesisGO:0007480800.012
regulation of nucleotide metabolic processGO:0006140620.012
regulation of cell projection organizationGO:0031344920.012
negative regulation of response to stimulusGO:00485852580.012
response to radiationGO:00093141550.011
regulation of localizationGO:00328792750.011
positive regulation of synapse assemblyGO:0051965290.011
nucleotide catabolic processGO:00091661090.011
dendrite guidanceGO:0070983210.011
mitotic cell cycle checkpointGO:0007093880.011
regulation of gtp catabolic processGO:0033124440.011
posttranscriptional gene silencingGO:0016441460.011
programmed cell deathGO:00125012570.011
Worm
protein heterooligomerizationGO:005129140.011
protein deglycosylationGO:000651710.011
chromosome organizationGO:00512763600.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
guanosine containing compound metabolic processGO:1901068740.011
chromatin organizationGO:00063252070.011
regulation of synapse structure and activityGO:00508031280.011
female gonad developmentGO:0008585120.011
protein neddylationGO:004511650.011
actin filament organizationGO:00070151260.011
regulation of response to biotic stimulusGO:0002831630.011
positive regulation of phosphate metabolic processGO:00459371390.011
signal transduction in response to dna damageGO:004277030.011
hematopoietic progenitor cell differentiationGO:000224410.011
mitotic spindle organizationGO:00070522200.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.011
negative regulation of synapse assemblyGO:0051964390.011
salivary gland morphogenesisGO:00074351450.011
regulation of small gtpase mediated signal transductionGO:0051056930.010
gtp metabolic processGO:0046039720.010
negative regulation of protein metabolic processGO:0051248850.010
chromosome separationGO:0051304420.010
photoreceptor cell differentiationGO:00465301700.010
macromolecular complex disassemblyGO:0032984370.010
microtubule cytoskeleton organization involved in mitosisGO:1902850520.010
developmental growthGO:00485892800.010
morphogenesis of an epitheliumGO:00020092760.010
regulation of hemocyte differentiationGO:0045610220.010
negative regulation of cell deathGO:0060548810.010
translational terminationGO:000641520.010
embryonic development via the syncytial blastodermGO:00017001480.010
appendage morphogenesisGO:00351073970.010
multi organism reproductive behaviorGO:00447051210.010

Rpn6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013