Drosophila melanogaster

14 known processes

nAcRalpha-34E (Dmel_CG32975)

nicotinic Acetylcholine Receptor alpha 34E

(Aliases: Dalpha5,CG32975,Dmel\CG32975,CT14633,CG4498,CG16878,BG:DS05899.5,BG:DS05899.4,anon-WO02059370.44,nAChR)

nAcRalpha-34E biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
salt aversionGO:003519930.094
ion transportGO:00068111450.089
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.079
eye morphogenesisGO:00485922600.075
store operated calcium entryGO:000211530.072
rhythmic processGO:00485111060.071
eye developmentGO:00016543230.068
adult behaviorGO:00305341370.067
Fly
organonitrogen compound metabolic processGO:19015643180.066
circadian behaviorGO:0048512760.063
rhythmic behaviorGO:0007622760.061
behavioral response to ethanolGO:0048149490.056
taxisGO:00423303040.054
sensory perception of salty tasteGO:005091430.054
intracellular signal transductionGO:00355563000.052
Human
negative regulation of cellular metabolic processGO:00313243820.048
g protein coupled receptor signaling pathwayGO:00071861360.047
circadian rhythmGO:00076231050.046
locomotory behaviorGO:00076261760.045
Fly
single organism behaviorGO:00447083910.042
Fly
negative regulation of biosynthetic processGO:00098902770.042
nucleotide metabolic processGO:00091171610.041
neurological system processGO:00508773580.041
Human
phosphorylationGO:00163102940.040
Human
metal ion transportGO:0030001740.040
Human
synaptic transmissionGO:00072682880.040
Human Fly
small molecule metabolic processGO:00442813050.039
positive regulation of cellular biosynthetic processGO:00313283160.039
sensory organ morphogenesisGO:00905962600.038
ribose phosphate metabolic processGO:00196931450.038
regulation of circadian rhythmGO:0042752490.038
ras protein signal transductionGO:0007265880.037
regulation of phosphate metabolic processGO:00192202100.037
Human
neuropeptide signaling pathwayGO:0007218450.037
ion transmembrane transportGO:00342201220.036
response to oxygen containing compoundGO:19017002000.035
cellular catabolic processGO:00442483720.034
response to other organismGO:00517072930.034
biological adhesionGO:00226101380.033
purine containing compound metabolic processGO:00725211550.031
negative regulation of nitrogen compound metabolic processGO:00511722650.031
positive regulation of nitrogen compound metabolic processGO:00511733540.031
carbohydrate derivative metabolic processGO:19011352170.031
neuron projection guidanceGO:00974852410.031
regulation of mitotic cell cycleGO:00073461900.031
regulation of molecular functionGO:00650092170.030
Human
cation transmembrane transportGO:0098655880.030
positive regulation of response to stimulusGO:00485843230.030
Human
endocytosisGO:00068973100.030
vesicle mediated transportGO:00161923810.030
purine ribonucleotide metabolic processGO:00091501450.030
phagocytosisGO:00069092150.029
response to alcoholGO:0097305950.029
negative regulation of cellular biosynthetic processGO:00313272770.029
response to abiotic stimulusGO:00096283410.029
Human Fly
positive regulation of biosynthetic processGO:00098913160.029
regulation of multicellular organismal developmentGO:20000264140.029
Human
small gtpase mediated signal transductionGO:0007264880.028
regulation of synapse structure and activityGO:00508031280.028
organophosphate metabolic processGO:00196371950.028
transcription from rna polymerase ii promoterGO:00063663680.028
neuromuscular junction developmentGO:00075281490.028
catabolic processGO:00090564090.028
regulation of small gtpase mediated signal transductionGO:0051056930.028
positive regulation of nucleobase containing compound metabolic processGO:00459353320.027
protein modification processGO:00362114380.027
Human
axon developmentGO:00615642970.027
regionalizationGO:00030024160.027
neuron recognitionGO:00080381010.027
regulation of phosphorus metabolic processGO:00511742100.027
Human
forebrain developmentGO:003090020.026
synaptic growth at neuromuscular junctionGO:00511241190.026
cation transportGO:00068121100.026
positive regulation of signalingGO:00230562430.026
Human
intracellular transportGO:00469072280.026
nucleobase containing small molecule metabolic processGO:00550861740.026
positive regulation of cell communicationGO:00106472500.026
Human
cell recognitionGO:00080371020.025
regulation of cellular ketone metabolic processGO:001056530.025
cell adhesionGO:00071551360.025
chemotaxisGO:00069352490.025
regulation of cellular amino acid metabolic processGO:000652100.025
response to organic substanceGO:00100332840.025
Human
larval behaviorGO:0030537420.025
transmembrane transportGO:00550851390.024
nucleobase containing compound catabolic processGO:00346551650.024
organic substance catabolic processGO:19015753080.024
protein complex biogenesisGO:00702712010.024
establishment of localization in cellGO:00516494020.024
positive regulation of signal transductionGO:00099672230.024
Human
protein localizationGO:00081042840.024
regulation of cell cycleGO:00517262910.024
regulation of cellular amine metabolic processGO:003323830.024
regulation of synaptic transmissionGO:0050804690.023
cognitionGO:00508901410.023
Human
peptide metabolic processGO:0006518800.023
circadian sleep wake cycleGO:0042745280.023
aromatic compound catabolic processGO:00194391660.023
cell cell adhesionGO:0098609260.023
regulation of nervous system developmentGO:00519602480.023
carbohydrate derivative biosynthetic processGO:1901137850.023
negative regulation of signalingGO:00230572190.023
cellular macromolecule localizationGO:00707272200.023
spindle organizationGO:00070512530.023
reproductive behaviorGO:00190981220.023
compound eye developmentGO:00487493070.023
synaptic target recognitionGO:0008039450.022
nucleoside phosphate metabolic processGO:00067531620.022
mitotic spindle organizationGO:00070522200.022
purine nucleoside triphosphate catabolic processGO:00091461080.022
multi organism behaviorGO:00517051750.022
body morphogenesisGO:001017120.022
regulation of localizationGO:00328792750.022
Human
negative regulation of nucleobase containing compound metabolic processGO:00459342610.022
purine nucleotide metabolic processGO:00061631460.022
regulation of anatomical structure sizeGO:00900661630.022
compound eye morphogenesisGO:00017452490.022
protein complex assemblyGO:00064612000.022
nucleoside catabolic processGO:00091641120.022
matingGO:00076181200.022
regulation of multi organism processGO:00439001310.022
purine ribonucleoside triphosphate metabolic processGO:00092051190.022
inorganic ion transmembrane transportGO:0098660730.022
Human
regulation of behaviorGO:0050795750.021
regulation of ras protein signal transductionGO:0046578930.021
purine nucleotide catabolic processGO:00061951090.021
negative regulation of cell communicationGO:00106482230.021
macromolecular complex assemblyGO:00650032560.021
single organism biosynthetic processGO:00447112060.021
protein phosphorylationGO:00064681690.021
Human
positive regulation of cellular catabolic processGO:0031331950.021
anatomical structure homeostasisGO:0060249970.021
synapse organizationGO:00508081960.021
neuromuscular synaptic transmissionGO:0007274670.021
regulation of cellular catabolic processGO:00313291570.021
sensory perceptionGO:00076001960.021
regulation of catalytic activityGO:00507901850.021
Human
negative regulation of multicellular organismal processGO:00512411420.021
Human
axon guidanceGO:00074112330.021
positive regulation of phosphorus metabolic processGO:00105621390.021
Human
camera type eye developmentGO:004301040.020
regulation of cellular component biogenesisGO:00440872010.020
telencephalon developmentGO:002153720.020
response to ethanolGO:0045471590.020
growthGO:00400073590.020
positive regulation of rna biosynthetic processGO:19026802660.020
positive regulation of gtpase activityGO:0043547430.020
regulation of purine nucleotide metabolic processGO:1900542620.020
organonitrogen compound biosynthetic processGO:19015661170.020
courtship behaviorGO:0007619680.020
eye photoreceptor cell developmentGO:0042462810.020
compound eye photoreceptor cell differentiationGO:00017511400.020
regulation of transcription from rna polymerase ii promoterGO:00063573780.020
multi organism reproductive behaviorGO:00447051210.020
organophosphate catabolic processGO:00464341120.020
negative regulation of response to stimulusGO:00485852580.020
cell proliferationGO:00082832990.020
Human
cellular nitrogen compound catabolic processGO:00442701650.020
cellular amino acid metabolic processGO:0006520610.020
establishment of protein localizationGO:00451841630.020
homeostatic processGO:00425921990.020
Human
multi multicellular organism processGO:00447061230.020
developmental maturationGO:00217001720.019
bolwig s organ developmentGO:005503480.019
associative learningGO:0008306650.019
negative regulation of rna metabolic processGO:00512532510.019
sensory perception of chemical stimulusGO:00076061160.019
nucleoside triphosphate catabolic processGO:00091431080.019
carboxylic acid metabolic processGO:0019752920.019
dorsal ventral pattern formationGO:00099531330.019
mitotic nuclear divisionGO:00070672130.019
purine ribonucleoside triphosphate catabolic processGO:00092071080.019
single organism catabolic processGO:00447122280.019
purine ribonucleoside catabolic processGO:00461301120.019
regulation of circadian sleep wake cycleGO:0042749250.019
negative regulation of gene expressionGO:00106293870.019
response to external biotic stimulusGO:00432072930.019
response to biotic stimulusGO:00096072940.019
organic cyclic compound catabolic processGO:19013611680.018
positive regulation of cell migrationGO:003033520.018
regulation of synapse assemblyGO:0051963940.018
organelle fissionGO:00482853400.018
axis specificationGO:00097981670.018
response to light stimulusGO:00094161240.018
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.018
compound eye photoreceptor developmentGO:0042051780.018
heterocycle catabolic processGO:00467001660.018
synapse assemblyGO:00074161430.018
connective tissue developmentGO:006144830.018
developmental growthGO:00485892800.018
kidney developmentGO:000182230.018
positive regulation of phosphate metabolic processGO:00459371390.018
Human
organic acid metabolic processGO:00060821030.018
deathGO:00162652840.018
cellular protein modification processGO:00064644380.018
Human
organic substance transportGO:00717022570.018
regulation of mitotic cell cycle phase transitionGO:19019901300.018
intracellular protein transportGO:00068861040.017
camera type eye morphogenesisGO:004859320.017
cell cell signaling involved in cell fate commitmentGO:00451682100.017
response to monosaccharideGO:003428440.017
positive regulation of macromolecule metabolic processGO:00106044050.017
Human
positive regulation of molecular functionGO:00440931360.017
Human
positive regulation of gene expressionGO:00106282900.017
mating behaviorGO:00076171060.017
response to lipopolysaccharideGO:003249640.017
positive regulation of developmental processGO:00510941430.017
Human
positive regulation of cell motilityGO:200014730.017
male mating behaviorGO:0060179700.017
regulation of cell differentiationGO:00455953020.017
response to painGO:004826530.017
regulation of transportGO:00510491810.017
Human
feeding behaviorGO:0007631500.017
cellular amide metabolic processGO:0043603800.017
nucleoside metabolic processGO:00091161270.017
purine containing compound catabolic processGO:00725231120.017
protein heterooligomerizationGO:005129140.017
antimicrobial humoral responseGO:0019730990.017
purine nucleoside metabolic processGO:00422781270.017
regulation of cell cycle phase transitionGO:19019871300.016
regulation of cell cycle processGO:00105641810.016
regulation of nucleotide metabolic processGO:0006140620.016
cellular response to chemical stimulusGO:00708871990.016
cell cycle phase transitionGO:00447701400.016
intraspecies interaction between organismsGO:005170340.016
regulation of catabolic processGO:00098941700.016
single organism intracellular transportGO:19025822070.016
positive regulation of catabolic processGO:00098961050.016
ribonucleotide metabolic processGO:00092591450.016
positive regulation of exocytosisGO:004592140.016
positive regulation of nucleic acid templated transcriptionGO:19035082660.016
response to glucoseGO:000974920.016
negative regulation of rna biosynthetic processGO:19026792400.016
retina development in camera type eyeGO:006004140.016
amine metabolic processGO:0009308120.016
cellular ketone metabolic processGO:0042180240.016
glycosyl compound catabolic processGO:19016581120.016
gtp catabolic processGO:0006184720.016
protein transportGO:00150311550.016
nucleotide catabolic processGO:00091661090.016
photoreceptor cell developmentGO:0042461960.016
carbohydrate derivative catabolic processGO:19011361180.016
multicellular organismal reproductive behaviorGO:00330571100.016
chemical homeostasisGO:0048878920.016
Human
positive regulation of macromolecule biosynthetic processGO:00105572830.016
appendage developmentGO:00487364010.016
photoreceptor cell differentiationGO:00465301700.016
defense response to other organismGO:00985422250.016
monovalent inorganic cation transportGO:0015672400.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
regulation of protein metabolic processGO:00512462560.016
Human
divalent metal ion transportGO:0070838260.015
Human
regulation of synaptic growth at neuromuscular junctionGO:0008582890.015
purine nucleoside triphosphate metabolic processGO:00091441190.015
olfactory learningGO:0008355560.015
regulation of immune system processGO:00026821760.015
cytoplasmic transportGO:00164821300.015
regulation of response to biotic stimulusGO:0002831630.015
nucleoside triphosphate metabolic processGO:00091411200.015
endomembrane system organizationGO:00102561190.015
memoryGO:0007613940.015
regulation of cyclic nucleotide metabolic processGO:0030799130.015
cell deathGO:00082192790.015
purine containing compound biosynthetic processGO:0072522300.015
oxoacid metabolic processGO:00434361030.015
negative regulation of signal transductionGO:00099682060.015
regulation of cellular protein metabolic processGO:00322682430.015
Human
embryonic morphogenesisGO:00485982060.015
ribonucleoside catabolic processGO:00424541120.015
response to extracellular stimulusGO:00099911160.015
cellular response to carbohydrate stimulusGO:007132240.015
open tracheal system developmentGO:00074242040.015
response to endogenous stimulusGO:00097191190.015
Human
gene silencingGO:00164581380.015
hindbrain developmentGO:003090220.015
regulation of developmental growthGO:00486381740.015
eye photoreceptor cell differentiationGO:00017541450.015
chromosome organizationGO:00512763600.015
mapk cascadeGO:00001651070.015
Human
positive regulation of nervous system developmentGO:0051962690.015
purine ribonucleotide catabolic processGO:00091541090.014
regulation of cell shapeGO:00083601130.014
negative regulation of transcription dna templatedGO:00458922370.014
immune system processGO:00023763470.014
imaginal disc derived wing morphogenesisGO:00074763370.014
ribonucleoside triphosphate metabolic processGO:00091991190.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
regulation of i kappab kinase nf kappab signalingGO:004312220.014
exocrine system developmentGO:00352721620.014
cellular amine metabolic processGO:0044106120.014
negative regulation of purine nucleotide biosynthetic processGO:190037230.014
nucleoside phosphate catabolic processGO:19012921100.014
positive regulation of nucleotide metabolic processGO:0045981550.014
cyclic nucleotide metabolic processGO:0009187280.014
positive regulation of purine nucleotide metabolic processGO:1900544550.014
positive regulation of gtp catabolic processGO:0033126430.014
programmed cell deathGO:00125012570.014
nuclear divisionGO:00002803320.014
ribonucleoside metabolic processGO:00091191270.014
nephron morphogenesisGO:007202830.014
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715780.014
positive regulation of rna metabolic processGO:00512542710.014
positive regulation of multicellular organismal processGO:00512401430.014
Human
actin filament based processGO:00300292200.014
regulation of adenylate cyclase activityGO:0045761120.014
embryonic development via the syncytial blastodermGO:00017001480.014
adult locomotory behaviorGO:0008344760.014
Fly
cell maturationGO:00484691440.014
inorganic cation transmembrane transportGO:0098662610.014
rna processingGO:00063961470.014
organonitrogen compound catabolic processGO:19015651280.014
regulation of intracellular signal transductionGO:19025312360.014
Human
negative regulation of developmental processGO:00510932010.014
regulation of ion transportGO:0043269390.014
Human
anterior posterior pattern specificationGO:00099521360.014
positive regulation of cellular component organizationGO:00511301560.014
olfactory behaviorGO:0042048970.013
regulation of gene expression epigeneticGO:00400291280.013
metal ion homeostasisGO:0055065440.013
Human
segmentationGO:00352822070.013
negative regulation of gene expression epigeneticGO:0045814770.013
purine nucleoside catabolic processGO:00061521120.013
positive regulation of intracellular signal transductionGO:19025331160.013
Human
regulation of mapk cascadeGO:0043408920.013
Human
response to radiationGO:00093141550.013
Fly
secretionGO:00469031090.013
chemosensory behaviorGO:00076351060.013
single organism cellular localizationGO:19025801800.013
positive regulation of hydrolase activityGO:0051345780.013
response to hexoseGO:000974630.013
cellular response to molecule of bacterial originGO:007121930.013
axonal defasciculationGO:0007414120.013
mitotic cell cycle phase transitionGO:00447721380.013
kidney epithelium developmentGO:007207330.013
potassium ion transportGO:0006813200.013
cell cell junction organizationGO:0045216550.013
cellular homeostasisGO:0019725800.013
Human
response to organophosphorusGO:004668320.013
positive regulation of phosphorylationGO:0042327870.013
Human
positive regulation of transcription dna templatedGO:00458932660.013
regulation of immune responseGO:00507761180.013
tissue morphogenesisGO:00487292970.013
alternative mrna splicing via spliceosomeGO:0000380600.013
sensory perception of painGO:001923340.013
imaginal disc derived appendage developmentGO:00487373990.013
regulation of cell developmentGO:00602842150.013
nephron tubule developmentGO:007208030.013
circadian sleep wake cycle processGO:0022410240.013
nephron developmentGO:007200630.013
signal transduction by phosphorylationGO:00230141070.013
Human
embryo development ending in birth or egg hatchingGO:00097921520.013
purine ribonucleoside metabolic processGO:00461281270.013
response to nutrient levelsGO:00316671140.013
glycosyl compound metabolic processGO:19016571270.012
rho protein signal transductionGO:0007266140.012
immune effector processGO:0002252980.012
imaginal disc pattern formationGO:0007447910.012
motor neuron axon guidanceGO:0008045580.012
regulation of cell deathGO:00109411730.012
digestive tract morphogenesisGO:00485461270.012
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.012
regulation of humoral immune responseGO:0002920510.012
spindle assemblyGO:0051225800.012
negative regulation of nucleic acid templated transcriptionGO:19035072400.012
regulation of antimicrobial humoral responseGO:0002759500.012
positive regulation of nucleoside metabolic processGO:0045979470.012
respiratory system developmentGO:00605412130.012
localization of cellGO:00516742570.012
actin cytoskeleton organizationGO:00300362060.012
dorsal ventral axis specificationGO:0009950660.012
nucleotide biosynthetic processGO:0009165340.012
mrna metabolic processGO:00160711240.012
regulation of response to stressGO:00801342000.012
regulation of programmed cell deathGO:00430671520.012
actin filament organizationGO:00070151260.012
heart processGO:0003015370.012
behavioral response to painGO:004826630.012
larval locomotory behaviorGO:0008345270.012
appendage morphogenesisGO:00351073970.012
positive regulation of nucleotide catabolic processGO:0030813460.012
regulation of cell proliferationGO:00421271630.012
Human
regulation of anatomical structure morphogenesisGO:00226032420.012
Human
mesenchymal cell differentiationGO:004876210.012
gastrulation involving germ band extensionGO:0010004360.012
production of molecular mediator of immune responseGO:0002440460.012
proteolysisGO:00065081920.012
ribonucleotide catabolic processGO:00092611090.012
cell divisionGO:00513012480.012
wing disc morphogenesisGO:00074723440.012
humoral immune responseGO:00069591170.012
positive regulation of cellular amino acid metabolic processGO:004576400.011
cell junction organizationGO:0034330570.011
nephron epithelium morphogenesisGO:007208830.011
cell motilityGO:00488702510.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
post embryonic appendage morphogenesisGO:00351203850.011
dendrite developmentGO:00163582040.011
gtp metabolic processGO:0046039720.011
negative regulation of protein metabolic processGO:0051248850.011
establishment or maintenance of cell polarityGO:00071631670.011
regulation of immune effector processGO:0002697520.011
axonogenesisGO:00074092900.011
cellular response to lipopolysaccharideGO:007122230.011
wing disc pattern formationGO:0035222660.011
regulation of hydrolase activityGO:0051336970.011
nephron epithelium developmentGO:007200930.011
response to organic cyclic compoundGO:0014070890.011
Human
limb developmentGO:006017310.011
cyclic nucleotide biosynthetic processGO:0009190250.011
salivary gland developmentGO:00074311620.011
peptide biosynthetic processGO:0043043420.011
locomotor rhythmGO:0045475560.011
guanosine containing compound catabolic processGO:1901069740.011
activation of innate immune responseGO:000221840.011
detection of stimulusGO:00516061560.011
mrna processingGO:00063971040.011
embryonic axis specificationGO:00005781070.011
organelle assemblyGO:00709251980.011
cyclic purine nucleotide metabolic processGO:0052652250.011
embryonic hindgut morphogenesisGO:0048619480.011
spinal cord developmentGO:002151010.011
rhabdomere developmentGO:0042052380.011
regulation of gene silencingGO:0060968630.011
guanosine containing compound metabolic processGO:1901068740.011
response to nitrogen compoundGO:1901698900.011
Human
organophosphate biosynthetic processGO:0090407460.011
negative regulation of cellular protein metabolic processGO:0032269850.011
sleepGO:0030431490.011
Fly
salivary gland morphogenesisGO:00074351450.011
morphogenesis of an epitheliumGO:00020092760.011
rna localizationGO:00064031150.011
learning or memoryGO:00076111410.011
cellular protein localizationGO:00346131600.010
regulation of epithelial cell proliferationGO:005067840.010
anterior posterior axis specificationGO:00099481090.010
bolwig s organ morphogenesisGO:000174680.010
regulation of response to external stimulusGO:00321011150.010
positive regulation of cellular amine metabolic processGO:003324000.010
calcium ion transportGO:0006816240.010
Human
apoptotic processGO:00069151590.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.010
detection of stimulus involved in sensory perceptionGO:0050906920.010
single organism membrane organizationGO:0044802930.010
cellularizationGO:0007349900.010
cellular response to biotic stimulusGO:007121640.010
immune response activating signal transductionGO:000275720.010
negative regulation of molecular functionGO:0044092510.010
Human
developmental programmed cell deathGO:00106231380.010
carbohydrate metabolic processGO:0005975820.010
mesenchymal cell developmentGO:001403110.010
notch signaling pathwayGO:00072191200.010
cellular response to decreased oxygen levelsGO:0036294300.010
lateral inhibitionGO:00463312060.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.010
retina morphogenesis in camera type eyeGO:006004220.010
regulation of neuron differentiationGO:00456641030.010
posttranscriptional regulation of gene expressionGO:00106081450.010
regulation of tube sizeGO:0035150460.010
regulation of camp biosynthetic processGO:0030817120.010
inter male aggressive behaviorGO:0002121600.010
regulation of antimicrobial peptide productionGO:0002784440.010
regulation of system processGO:0044057360.010

nAcRalpha-34E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
nervous system diseaseDOID:86300.034
cardiovascular system diseaseDOID:128700.014
sensory system diseaseDOID:005015500.014
disease of metabolismDOID:001466700.014
eye and adnexa diseaseDOID:149200.013
eye diseaseDOID:561400.013
musculoskeletal system diseaseDOID:1700.012
urinary system diseaseDOID:1800.011
renal tubular transport diseaseDOID:44700.011
kidney diseaseDOID:55700.011
central nervous system diseaseDOID:33100.011